PubMed

Uracil misincorporation into DNA and folic acid supplementation.

Hazra A, Selhub J, Chao WH, Ueland PM, Hunter DJ, Baron JA.

Am J Clin Nutr. 2009 Nov 18. [Epub ahead of print]PMID: 19923375 [PubMed - as supplied by publisher]Related articles

Vitamin B-6 Intake Is Inversely Related to, and the Requirement Is Affected by, Inflammation Status.

Morris MS, Sakakeeny L, Jacques PF, Picciano MF, Selhub J.

J Nutr. 2009 Nov 11. [Epub ahead of print]PMID: 19906811 [PubMed - as supplied by publisher]Related articles

A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma.

Wu K, Platz EA, Willett WC, Fuchs CS, Selhub J, Rosner BA, Hunter DJ, Giovannucci E.

Am J Clin Nutr. 2009 Oct 28. [Epub ahead of print]PMID: 19864409 [PubMed - as supplied by publisher]Related articles

Serum creatinine and prostate cancer risk in a prospective study.

Weinstein SJ, Mackrain K, Stolzenberg-Solomon RZ, Selhub J, Virtamo J, Albanes D.

Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2643-9. Epub 2009 Sep 15.PMID: 19755655 [PubMed - in process]Related articles

Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.

Hazra A, Kraft P, Lazarus R, Chen C, Chanock SJ, Jacques P, Selhub J, Hunter DJ.

Hum Mol Genet. 2009 Dec 1;18(23):4677-87. Epub 2009 Sep 10.PMID: 19744961 [PubMed - in process]Related articlesFree article

Plasma vitamin B(6) and risk of myocardial infarction in women.

Page JH, Ma J, Chiuve SE, Stampfer MJ, Selhub J, Manson JE, Rimm EB.

Circulation. 2009 Aug 25;120(8):649-55. Epub 2009 Aug 10.PMID: 19667235 [PubMed - indexed for MEDLINE]Related articles

Plasma levels of B vitamins and colorectal cancer risk: the multiethnic cohort study.

Le Marchand L, White KK, Nomura AM, Wilkens LR, Selhub JS, Tiirikainen M, Goodman MT, Murphy SP, Henderson BE, Kolonel LN.

Cancer Epidemiol Biomarkers Prev. 2009 Aug;18(8):2195-201.PMID: 19661077 [PubMed - indexed for MEDLINE]Related articles

Telomere length in peripheral blood mononuclear cells is associated with folate status in men.

Paul L, Cattaneo M, D'Angelo A, Sampietro F, Fermo I, Razzari C, Fontana G, Eugene N, Jacques PF, Selhub J.

J Nutr. 2009 Jul;139(7):1273-8. Epub 2009 May 20.PMID: 19458030 [PubMed - indexed for MEDLINE]Related articles

Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community.

Joseph J, Pencina MJ, Wang TJ, Hayes L, Tofler GH, Jacques P, Selhub J, Levy D, D'Agostino RB Sr, Benjamin EJ, Vasan RS.

J Hypertens. 2009 Jun;27(6):1317-24.PMID: 19357531 [PubMed - indexed for MEDLINE]Related articles

Prospective study of plasma vitamin B6 and risk of colorectal cancer in men.

Lee JE, Li H, Giovannucci E, Lee IM, Selhub J, Stampfer M, Ma J.

Cancer Epidemiol Biomarkers Prev. 2009 Apr;18(4):1197-202. Epub 2009 Mar 31.PMID: 19336555 [PubMed - indexed for MEDLINE]Related articles

Mild methionine excess does not affect thymidylate synthesis or inflammation markers expression in human aortic endothelial cells.

Achón M, Alonso-Aperte E, Varela-Moreiras G, Selhub J.

Ann Nutr Metab. 2009;54(1):28-34. Epub 2009 Feb 27.PMID: 19246892 [PubMed - indexed for MEDLINE]Related articles

Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency.

Selhub J, Morris MS, Jacques PF, Rosenberg IH.

Am J Clin Nutr. 2009 Feb;89(2):702S-6S. Epub 2009 Jan 13. Erratum in: Am J Clin Nutr. 2009 Jun;89(6):1951. PMID: 19141696 [PubMed - indexed for MEDLINE]Related articles

High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial.

Hodis HN, Mack WJ, Dustin L, Mahrer PR, Azen SP, Detrano R, Selhub J, Alaupovic P, Liu CR, Liu CH, Hwang J, Wilcox AG, Selzer RH; BVAIT Research Group.

Stroke. 2009 Mar;40(3):730-6. Epub 2008 Dec 31.PMID: 19118243 [PubMed - indexed for MEDLINE]Related articles

Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study.

Lieb W, Larson MG, Benjamin EJ, Yin X, Tofler GH, Selhub J, Jacques PF, Wang TJ, Vita JA, Levy D, Vasan RS, Mitchell GF.

Circulation. 2009 Jan 6;119(1):37-43. Epub 2008 Dec 22.PMID: 19103986 [PubMed - indexed for MEDLINE]Related articles

Not all cases of neural-tube defect can be prevented by increasing the intake of folic acid.

Heseker HB, Mason JB, Selhub J, Rosenberg IH, Jacques PF.

Br J Nutr. 2009 Jul;102(2):173-80. Epub 2008 Dec 16. Review.PMID: 19079944 [PubMed - indexed for MEDLINE]Related articles

The relation of plasma homocysteine to radiographic knee osteoarthritis.

Fayfman M, Niu J, Zhang YQ, Felson DT, Sack B, Aliabadi P, Selhub J, Hunter DJ.

Osteoarthritis Cartilage. 2009 Jun;17(6):766-71. Epub 2008 Nov 30.PMID: 19073367 [PubMed - in process]Related articlesFree article

Micronutrient deficiencies are associated with impaired immune response and higher burden of respiratory infections in elderly Ecuadorians.

Hamer DH, Sempértegui F, Estrella B, Tucker KL, Rodríguez A, Egas J, Dallal GE, Selhub J, Griffiths JK, Meydani SN.

J Nutr. 2009 Jan;139(1):113-9. Epub 2008 Dec 3.PMID: 19056665 [PubMed - indexed for MEDLINE]Related articles

Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine.

Troen AM, Chao WH, Crivello NA, D'Anci KE, Shukitt-Hale B, Smith DE, Selhub J, Rosenberg IH.

J Nutr. 2008 Dec;138(12):2502-9.PMID: 19022979 [PubMed - indexed for MEDLINE]Related articles

A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate.

Kalmbach RD, Choumenkovitch SF, Troen AP, Jacques PF, D'Agostino R, Selhub J.

J Nutr. 2008 Dec;138(12):2323-7.PMID: 19022952 [PubMed - indexed for MEDLINE]Related articles

Baseline characteristics of participants in the Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT) Trial.

Bostom AG, Carpenter MA, Hunsicker L, Jacques PF, Kusek JW, Levey AS, McKenney JL, Mercier RY, Pfeffer MA, Selhub J; FAVORIT Study Investigators.

Am J Kidney Dis. 2009 Jan;53(1):121-8. Epub 2008 Nov 20.PMID: 19022547 [PubMed - indexed for MEDLINE]Related articles

One-carbon metabolism biomarkers and risk of colon and rectal cancers.

Weinstein SJ, Albanes D, Selhub J, Graubard B, Lim U, Taylor PR, Virtamo J, Stolzenberg-Solomon R.

Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3233-40.PMID: 18990766 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating folic acid in plasma: relation to folic acid fortification.

Kalmbach RD, Choumenkovitch SF, Troen AM, D'Agostino R, Jacques PF, Selhub J.

Am J Clin Nutr. 2008 Sep;88(3):763-8.PMID: 18779294 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants of FUT2 are associated with plasma vitamin B12 levels.

Hazra A, Kraft P, Selhub J, Giovannucci EL, Thomas G, Hoover RN, Chanock SJ, Hunter DJ.

Nat Genet. 2008 Oct;40(10):1160-2. Epub 2008 Sep 7.PMID: 18776911 [PubMed - indexed for MEDLINE]Related articlesFree article

B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice.

Troen AM, Shea-Budgell M, Shukitt-Hale B, Smith DE, Selhub J, Rosenberg IH.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12474-9. Epub 2008 Aug 18.PMID: 18711131 [PubMed - indexed for MEDLINE]Related articlesFree article

Public health significance of supplementation or fortification of grain products with folic acid.

Selhub J, Rosenberg IH.

Food Nutr Bull. 2008 Jun;29(2 Suppl):S173-6. Review. No abstract available. PMID: 18709890 [PubMed - indexed for MEDLINE]Related articles

Public health significance of elevated homocysteine.

Selhub J.

Food Nutr Bull. 2008 Jun;29(2 Suppl):S116-25. Review.PMID: 18709886 [PubMed - indexed for MEDLINE]Related articles

The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B12 status.

Selhub J, Jacques PF, Dallal G, Choumenkovitch S, Rogers G.

Food Nutr Bull. 2008 Jun;29(2 Suppl):S67-73. Review.PMID: 18709882 [PubMed - indexed for MEDLINE]Related articles

Prediagnostic plasma folate and the risk of death in patients with colorectal cancer.

Wolpin BM, Wei EK, Ng K, Meyerhardt JA, Chan JA, Selhub J, Giovannucci EL, Fuchs CS.

J Clin Oncol. 2008 Jul 1;26(19):3222-8.PMID: 18591557 [PubMed - indexed for MEDLINE]Related articles

Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study.

Seshadri S, Wolf PA, Beiser AS, Selhub J, Au R, Jacques PF, Yoshita M, Rosenberg IH, D'Agostino RB, DeCarli C.

Arch Neurol. 2008 May;65(5):642-9.PMID: 18474741 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004.

Morris MS, Picciano MF, Jacques PF, Selhub J.

Am J Clin Nutr. 2008 May;87(5):1446-54.PMID: 18469270 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and women.

McLean RR, Jacques PF, Selhub J, Fredman L, Tucker KL, Samelson EJ, Kiel DP, Cupples LA, Hannan MT.

J Clin Endocrinol Metab. 2008 Jun;93(6):2206-12. Epub 2008 Mar 25.PMID: 18364381 [PubMed - indexed for MEDLINE]Related articlesFree article

Correspondence: will increasing folic acid in fortified grain products further reduce neural tube defects without causing harm?

Morris MS, Jacques PF, Rosenberg IH, Selhub J.

Pediatr Res. 2008 Apr;63(4):450; author reply 450-1. No abstract available. PMID: 18356757 [PubMed - indexed for MEDLINE]Related articles

Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women.

Lin J, Lee IM, Cook NR, Selhub J, Manson JE, Buring JE, Zhang SM.

Am J Clin Nutr. 2008 Mar;87(3):734-43.PMID: 18326613 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations.

Selhub J, Morris MS, Jacques PF.

Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19995-20000. Epub 2007 Dec 4.PMID: 18056804 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma cysteinylglycine levels and breast cancer risk in women.

Lin J, Manson JE, Selhub J, Buring JE, Zhang SM.

Cancer Res. 2007 Dec 1;67(23):11123-7.PMID: 18056435 [PubMed - indexed for MEDLINE]Related articlesFree article

Preliminary evidence shows that folic acid fortification of the food supply is associated with higher methotrexate dosing in patients with rheumatoid arthritis.

Arabelovic S, Sam G, Dallal GE, Jacques PF, Selhub J, Rosenberg IH, Roubenoff R.

J Am Coll Nutr. 2007 Oct;26(5):453-5.PMID: 17914133 [PubMed - indexed for MEDLINE]Related articlesFree article

Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study.

Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF, Fox CS, Meigs JB, Levy D, Larson MG, Selhub J, D'Agostino RB Sr, Wang TJ, Vasan RS.

Circulation. 2007 Aug 28;116(9):984-92. Epub 2007 Aug 13.PMID: 17698726 [PubMed - indexed for MEDLINE]Related articlesFree article

A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis.

Mason JB, Dickstein A, Jacques PF, Haggarty P, Selhub J, Dallal G, Rosenberg IH.

Cancer Epidemiol Biomarkers Prev. 2007 Jul;16(7):1325-9.PMID: 17626997 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: the Framingham Heart Study.

Levy D, Hwang SJ, Kayalar A, Benjamin EJ, Vasan RS, Parise H, Larson MG, Wang TJ, Selhub J, Jacques PF, Vita JA, Keyes MJ, Mitchell GF.

Circulation. 2007 Jun 19;115(24):3079-85. Epub 2007 May 28.PMID: 17533184 [PubMed - indexed for MEDLINE]Related articlesFree article

Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet.

Troen AM, French EE, Roberts JF, Selhub J, Ordovas JM, Parnell LD, Lai CQ.

Age (Dordr). 2007 Mar;29(1):29-39. Epub 2006 Nov 25.PMID: 19424828 [PubMed - in process]Related articlesFree article

Multiple biomarkers and the risk of incident hypertension.

Wang TJ, Gona P, Larson MG, Levy D, Benjamin EJ, Tofler GH, Jacques PF, Meigs JB, Rifai N, Selhub J, Robins SJ, Newton-Cheh C, Vasan RS.

Hypertension. 2007 Mar;49(3):432-8. Epub 2007 Jan 22.PMID: 17242302 [PubMed - indexed for MEDLINE]Related articlesFree article

Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification.

Morris MS, Jacques PF, Rosenberg IH, Selhub J.

Am J Clin Nutr. 2007 Jan;85(1):193-200.PMID: 17209196 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple biomarkers for the prediction of first major cardiovascular events and death.

Wang TJ, Gona P, Larson MG, Tofler GH, Levy D, Newton-Cheh C, Jacques PF, Rifai N, Selhub J, Robins SJ, Benjamin EJ, D'Agostino RB, Vasan RS.

N Engl J Med. 2006 Dec 21;355(25):2631-9.PMID: 17182988 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of the affinity/HPLC method for quantitative estimation of folic acid in enriched cereal-grain products.

Póo-Prieto R, Haytowitz DB, Holden JM, Rogers G, Choumenkovitch SF, Jacques PF, Selhub J.

J Nutr. 2006 Dec;136(12):3079-83.PMID: 17116723 [PubMed - indexed for MEDLINE]Related articlesFree article

The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice.

Troen AM, Shukitt-Hale B, Chao WH, Albuquerque B, Smith DE, Selhub J, Rosenberg J.

J Alzheimers Dis. 2006 Aug;9(4):381-92.PMID: 16917146 [PubMed - indexed for MEDLINE]Related articles

Association of a 31 bp VNTR in the CBS gene with postload homocysteine concentrations in the Framingham Offspring Study.

Lievers KJ, Kluijtmans LA, Blom HJ, Wilson PW, Selhub J, Ordovas JM.

Eur J Hum Genet. 2006 Oct;14(10):1125-9. Epub 2006 Jun 21.PMID: 16791140 [PubMed - indexed for MEDLINE]Related articlesFree article

The many facets of hyperhomocysteinemia: studies from the Framingham cohorts.

Selhub J.

J Nutr. 2006 Jun;136(6 Suppl):1726S-1730S. Review.PMID: 16702347 [PubMed - indexed for MEDLINE]Related articlesFree article

The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population.

Scott TM, Peter I, Tucker KL, Arsenault L, Bergethon P, Bhadelia R, Buell J, Collins L, Dashe JF, Griffith J, Hibberd P, Leins D, Liu T, Ordovas JM, Patz S, Price LL, Qiu WQ, Sarnak M, Selhub J, Smaldone L, Wagner C, Wang L, Weiner D, Yee J, Rosenberg I, Folstein M.

Int J Geriatr Psychiatry. 2006 Jun;21(6):519-28.PMID: 16645938 [PubMed - indexed for MEDLINE]Related articles

Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase.

Anguera MC, Field MS, Perry C, Ghandour H, Chiang EP, Selhub J, Shane B, Stover PJ.

J Biol Chem. 2006 Jul 7;281(27):18335-42. Epub 2006 Apr 20.PMID: 16627483 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study.

Cho E, Zeisel SH, Jacques P, Selhub J, Dougherty L, Colditz GA, Willett WC.

Am J Clin Nutr. 2006 Apr;83(4):905-11.PMID: 16600945 [PubMed - indexed for MEDLINE]Related articlesFree article