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    Results: 1 to 50 of 307

    1.

    Mobility performance tests for discriminating high risk of frailty in community-dwelling older women.

    Kim MJ, Yabushita N, Kim MK, Nemoto M, Seino S, Tanaka K.

    Arch Gerontol Geriatr. 2009 Nov 23. [Epub ahead of print]PMID: 19939477 [PubMed - as supplied by publisher]

    2.

    Mature acinar cells are refractory to carcinoma development by targeted activation of Ras oncogene in adult rats.

    Tanaka H, Fukamachi K, Futakuchi M, Alexander DB, Long N, Tamamushi S, Minami K, Seino S, Ohara H, Joh T, Tsuda H.

    Cancer Sci. 2009 Oct 22. [Epub ahead of print]PMID: 19917056 [PubMed - as supplied by publisher]Related articles

    3.

    Gold nanoparticles prepared with a room-temperature ionic liquid-radiation irradiation method.

    Tsuda T, Seino S, Kuwabata S.

    Chem Commun (Camb). 2009 Nov 28;(44):6792-4. Epub 2009 Sep 30.PMID: 19885481 [PubMed - in process]Related articles

    4.

    Roles of cAMP signalling in insulin granule exocytosis.

    Seino S, Takahashi H, Fujimoto W, Shibasaki T.

    Diabetes Obes Metab. 2009 Nov;11 Suppl 4:180-8.PMID: 19817800 [PubMed - in process]Related articles

    5.

    beta-Cell research - A decade of rapid growth.

    Ahrén B, Accili D, Boitard C, Efendic S, Henquin JC, Seino S, Steiner DF, Cerasi E.

    Diabetes Obes Metab. 2009 Nov;11 Suppl 4:iv-ix. No abstract available. PMID: 19817782 [PubMed - in process]Related articles

    6.

    LKB1 regulates pancreatic beta cell size, polarity, and function.

    Granot Z, Swisa A, Magenheim J, Stolovich-Rain M, Fujimoto W, Manduchi E, Miki T, Lennerz JK, Stoeckert CJ Jr, Meyuhas O, Seino S, Permutt MA, Piwnica-Worms H, Bardeesy N, Dor Y.

    Cell Metab. 2009 Oct;10(4):296-308.PMID: 19808022 [PubMed - in process]Related articles

    7.

    The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylurea drugs.

    Zhang CL, Katoh M, Shibasaki T, Minami K, Sunaga Y, Takahashi H, Yokoi N, Iwasaki M, Miki T, Seino S.

    Science. 2009 Jul 31;325(5940):607-10.PMID: 19644119 [PubMed - indexed for MEDLINE]Related articles

    8.

    Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis.

    Sugawara K, Shibasaki T, Mizoguchi A, Saito T, Seino S.

    Genes Cells. 2009 Apr;14(4):445-56.PMID: 19335615 [PubMed - indexed for MEDLINE]Related articles

    9.

    Niflumic acid-sensitive ion channels play an important role in the induction of glucose-stimulated insulin secretion by cyclic AMP in mice.

    Fujimoto W, Miki T, Ogura T, Zhang M, Seino Y, Satin LS, Nakaya H, Seino S.

    Diabetologia. 2009 May;52(5):863-72. Epub 2009 Mar 6.PMID: 19266181 [PubMed - indexed for MEDLINE]Related articles

    10.

    Proteomic profiling of KATP channel-deficient hypertensive heart maps risk for maladaptive cardiomyopathic outcome.

    Zlatkovic J, Arrell DK, Kane GC, Miki T, Seino S, Terzic A.

    Proteomics. 2009 Mar;9(5):1314-25.PMID: 19253285 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Severe hypophosphatemic osteomalacia with Fanconi syndrome, renal tubular acidosis, vitamin D deficiency and primary biliary cirrhosis.

    Bando H, Hashimoto N, Hirota Y, Sakaguchi K, Hisa I, Inoue Y, Imanishi Y, Seino S, Kaji H.

    Intern Med. 2009;48(5):353-8. Epub 2009 Mar 2.PMID: 19252361 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function.

    Niimura M, Miki T, Shibasaki T, Fujimoto W, Iwanaga T, Seino S.

    J Cell Physiol. 2009 Jun;219(3):652-8.PMID: 19170062 [PubMed - indexed for MEDLINE]Related articles

    13.

    Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery.

    Kamei K, Mukai Y, Kojima H, Yoshikawa T, Yoshikawa M, Kiyohara G, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.

    Biomaterials. 2009 Mar;30(9):1809-14. Epub 2009 Jan 10.PMID: 19136151 [PubMed - indexed for MEDLINE]Related articles

    14.

    Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

    Ravier MA, Nenquin M, Miki T, Seino S, Henquin JC.

    Endocrinology. 2009 Jan;150(1):33-45. Epub 2008 Sep 11.PMID: 18787024 [PubMed - indexed for MEDLINE]Related articles

    15.

    Mutations in the small heterodimer partner gene increase morbidity risk in Japanese type 2 diabetes patients.

    Enya M, Horikawa Y, Kuroda E, Yonemaru K, Tonooka N, Tomura H, Oda N, Yokoi N, Yamagata K, Shihara N, Iizuka K, Saibara T, Seino S, Takeda J.

    Hum Mutat. 2008 Nov;29(11):E271-7.PMID: 18781616 [PubMed - indexed for MEDLINE]Related articles

    16.

    Embryonic stem cell therapy of heart failure in genetic cardiomyopathy.

    Yamada S, Nelson TJ, Crespo-Diaz RJ, Perez-Terzic C, Liu XK, Miki T, Seino S, Behfar A, Terzic A.

    Stem Cells. 2008 Oct;26(10):2644-53. Epub 2008 Jul 31.PMID: 18669912 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Identification of a major locus for islet inflammation and fibrosis in the spontaneously diabetic Torii rat.

    Fuse M, Yokoi N, Shinohara M, Masuyama T, Kitazawa R, Kitazawa S, Seino S.

    Physiol Genomics. 2008 Sep 17;35(1):96-105. Epub 2008 Jul 8.PMID: 18612083 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    The effects of rewarding ventral tegmental area stimulation and environmental enrichment on lipopolysaccharide-induced sickness behavior and cytokine expression in female rats.

    Kentner AC, Takeuchi A, James JS, Miki T, Seino S, Hayley S, Bielajew C.

    Brain Res. 2008 Jun 27;1217:50-61. Epub 2008 Apr 25.PMID: 18511025 [PubMed - indexed for MEDLINE]Related articles

    19.

    Pancreatic acinar-to-beta cell transdifferentiation in vitro.

    Minami K, Seino S.

    Front Biosci. 2008 May 1;13:5824-37. Review.PMID: 18508625 [PubMed - indexed for MEDLINE]Related articles

    20.

    Involvement of Exoc3l, a protein structurally related to the exocyst subunit Sec6, in insulin secretion.

    Saito T, Shibasaki T, Seino S.

    Biomed Res. 2008 Apr;29(2):85-91.PMID: 18480549 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    [Regeneration of the pancreas]

    Minami K, Seino S.

    Nippon Rinsho. 2008 May;66(5):926-31. Review. Japanese. PMID: 18464512 [PubMed - indexed for MEDLINE]Related articles

    22.

    Role of sarcolemmal ATP-sensitive K+ channels in the regulation of sinoatrial node automaticity: an evaluation using Kir6.2-deficient mice.

    Fukuzaki K, Sato T, Miki T, Seino S, Nakaya H.

    J Physiol. 2008 Jun 1;586(Pt 11):2767-78. Epub 2008 Apr 17.PMID: 18420708 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Role of cadherin-mediated cell-cell adhesion in pancreatic exocrine-to-endocrine transdifferentiation.

    Minami K, Okano H, Okumachi A, Seino S.

    J Biol Chem. 2008 May 16;283(20):13753-61. Epub 2008 Mar 10.PMID: 18332139 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Sonochemical immobilization of noble metal nanoparticles on the surface of maghemite: mechanism and morphological control of the products.

    Mizukoshi Y, Tsuru Y, Tominaga A, Seino S, Masahashi N, Tanabe S, Yamamoto TA.

    Ultrason Sonochem. 2008 Jul;15(5):875-80. Epub 2008 Jan 15.PMID: 18282732 [PubMed]Related articles

    25.

    Identification and functional analysis of CBLB mutations in type 1 diabetes.

    Yokoi N, Fujiwara Y, Wang HY, Kitao M, Hayashi C, Someya T, Kanamori M, Oiso Y, Tajima N, Yamada Y, Seino Y, Ikegami H, Seino S.

    Biochem Biophys Res Commun. 2008 Mar 28;368(1):37-42. Epub 2008 Jan 15.PMID: 18201552 [PubMed - indexed for MEDLINE]Related articles

    26.

    Isx participates in the maintenance of vitamin A metabolism by regulation of beta-carotene 15,15'-monooxygenase (Bcmo1) expression.

    Seino Y, Miki T, Kiyonari H, Abe T, Fujimoto W, Kimura K, Takeuchi A, Takahashi Y, Oiso Y, Iwanaga T, Seino S.

    J Biol Chem. 2008 Feb 22;283(8):4905-11. Epub 2007 Dec 19.PMID: 18093975 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    KATP channels confer survival advantage in cocaine overdose.

    Reyes S, Kane GC, Miki T, Seino S, Terzic A.

    Mol Psychiatry. 2007 Dec;12(12):1060-1. No abstract available. PMID: 18043710 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    KATP channel-deficient pancreatic beta-cells are streptozotocin resistant because of lower GLUT2 activity.

    Xu J, Zhang L, Chou A, Allaby T, Bélanger G, Radziuk J, Jasmin BJ, Miki T, Seino S, Renaud JM.

    Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E326-35. Epub 2007 Nov 27.PMID: 18042662 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.

    Shibasaki T, Takahashi H, Miki T, Sunaga Y, Matsumura K, Yamanaka M, Zhang C, Tamamoto A, Satoh T, Miyazaki J, Seino S.

    Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19333-8. Epub 2007 Nov 26.PMID: 18040047 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    Dmbx1 is essential in agouti-related protein action.

    Fujimoto W, Shiuchi T, Miki T, Minokoshi Y, Takahashi Y, Takeuchi A, Kimura K, Saito M, Iwanaga T, Seino S.

    Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15514-9. Epub 2007 Sep 14.PMID: 17873059 [PubMed - indexed for MEDLINE]Related articlesFree article

    31.

    Disruption of Kir6.2-containing ATP-sensitive potassium channels impairs maintenance of hypoxic gasping in mice.

    Miyake A, Yamada K, Kosaka T, Miki T, Seino S, Inagaki N.

    Eur J Neurosci. 2007 Apr;25(8):2349-63.PMID: 17445233 [PubMed - indexed for MEDLINE]Related articles

    32.

    Genetic reconstitution of autoimmune type 1 diabetes with two major susceptibility genes in the rat.

    Yokoi N, Hayashi C, Fujiwara Y, Wang HY, Seino S.

    Diabetes. 2007 Feb;56(2):506-12.PMID: 17259398 [PubMed - indexed for MEDLINE]Related articlesFree article

    33.

    KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation.

    Olson TM, Alekseev AE, Moreau C, Liu XK, Zingman LV, Miki T, Seino S, Asirvatham SJ, Jahangir A, Terzic A.

    Nat Clin Pract Cardiovasc Med. 2007 Feb;4(2):110-6.PMID: 17245405 [PubMed - indexed for MEDLINE]Related articlesFree article

    34.

    Induction by NeuroD of the components required for regulated exocytosis.

    Ishizuka N, Minami K, Okumachi A, Okuno M, Seino S.

    Biochem Biophys Res Commun. 2007 Mar 2;354(1):271-7. Epub 2007 Jan 10.PMID: 17217914 [PubMed - indexed for MEDLINE]Related articles

    35.

    KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart.

    Gumina RJ, O'Cochlain DF, Kurtz CE, Bast P, Pucar D, Mishra P, Miki T, Seino S, Macura S, Terzic A.

    Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H1706-13. Epub 2006 Dec 22.PMID: 17189350 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Gene knockout of the KCNJ8-encoded Kir6.1 K(ATP) channel imparts fatal susceptibility to endotoxemia.

    Kane GC, Lam CF, O'Cochlain F, Hodgson DM, Reyes S, Liu XK, Miki T, Seino S, Katusic ZS, Terzic A.

    FASEB J. 2006 Nov;20(13):2271-80.PMID: 17077304 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant.

    Yamada S, Kane GC, Behfar A, Liu XK, Dyer RB, Faustino RS, Miki T, Seino S, Terzic A.

    J Physiol. 2006 Dec 15;577(Pt 3):1053-65. Epub 2006 Oct 12.PMID: 17038430 [PubMed - indexed for MEDLINE]Related articlesFree article

    38.

    Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes.

    Okuno M, Minami K, Okumachi A, Miyawaki K, Yokoi N, Toyokuni S, Seino S.

    Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E158-65. Epub 2006 Aug 22.PMID: 16926384 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects.

    Yokoi N, Kanamori M, Horikawa Y, Takeda J, Sanke T, Furuta H, Nanjo K, Mori H, Kasuga M, Hara K, Kadowaki T, Tanizawa Y, Oka Y, Iwami Y, Ohgawara H, Yamada Y, Seino Y, Yano H, Cox NJ, Seino S.

    Diabetes. 2006 Aug;55(8):2379-86.PMID: 16873704 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    Cellular expression of Noc2, a Rab effector protein, in endocrine and exocrine tissues in the mouse.

    Teramae H, Fujimoto W, Seino S, Iwanaga T.

    Histochem Cell Biol. 2007 Jan;127(1):1-11. Epub 2006 Jul 12.PMID: 16835753 [PubMed - indexed for MEDLINE]Related articles

    41.

    Spontaneous recovery from hyperglycemia by regeneration of pancreatic beta-cells in Kir6.2G132S transgenic mice.

    Oyama K, Minami K, Ishizaki K, Fuse M, Miki T, Seino S.

    Diabetes. 2006 Jul;55(7):1930-8.PMID: 16804060 [PubMed - indexed for MEDLINE]Related articlesFree article

    42.

    Cerebral glucose transporters expression and spatial learning in the K-ATP Kir6.2(-/-) knockout mice.

    Choeiri C, Staines WA, Miki T, Seino S, Renaud JM, Teutenberg K, Messier C.

    Behav Brain Res. 2006 Sep 25;172(2):233-9. Epub 2006 Jun 23.PMID: 16797737 [PubMed - indexed for MEDLINE]Related articles

    43.

    KCNJ11 gene knockout of the Kir6.2 KATP channel causes maladaptive remodeling and heart failure in hypertension.

    Kane GC, Behfar A, Dyer RB, O'Cochlain DF, Liu XK, Hodgson DM, Reyes S, Miki T, Seino S, Terzic A.

    Hum Mol Genet. 2006 Aug 1;15(15):2285-97. Epub 2006 Jun 16.PMID: 16782803 [PubMed - indexed for MEDLINE]Related articlesFree article

    44.

    Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion.

    Kawaguchi M, Minami K, Nagashima K, Seino S.

    J Biol Chem. 2006 May 12;281(19):13015-20. Epub 2006 Mar 16.PMID: 16543239 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Behavioral phenotyping of mice lacking the K ATP channel subunit Kir6.2.

    Deacon RM, Brook RC, Meyer D, Haeckel O, Ashcroft FM, Miki T, Seino S, Liss B.

    Physiol Behav. 2006 Apr 15;87(4):723-33. Epub 2006 Mar 10.PMID: 16530794 [PubMed - indexed for MEDLINE]Related articles

    46.

    Physical and functional interaction of noc2/rab3 in exocytosis.

    Shibasaki T, Seino S.

    Methods Enzymol. 2005;403:408-19.PMID: 16473607 [PubMed - indexed for MEDLINE]Related articles

    47.

    PDX-1 protein is internalized by lipid raft-dependent macropinocytosis.

    Noguchi H, Matsumoto S, Okitsu T, Iwanaga Y, Yonekawa Y, Nagata H, Matsushita M, Wei FY, Matsui H, Minami K, Seino S, Masui Y, Futaki S, Tanaka K.

    Cell Transplant. 2005;14(9):637-45.PMID: 16405074 [PubMed - indexed for MEDLINE]Related articles

    48.

    International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels.

    Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA.

    Pharmacol Rev. 2005 Dec;57(4):509-26. Review. No abstract available. PMID: 16382105 [PubMed - indexed for MEDLINE]Related articlesFree article

    49.

    Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K+ channels.

    Sun HS, Feng ZP, Miki T, Seino S, French RJ.

    J Neurophysiol. 2006 Apr;95(4):2590-601. Epub 2005 Dec 14.PMID: 16354731 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    Identification and characterization of a novel member of the ATP-sensitive K+ channel subunit family, Kir6.3, in zebrafish.

    Zhang C, Miki T, Shibasaki T, Yokokura M, Saraya A, Seino S.

    Physiol Genomics. 2006 Feb 14;24(3):290-7. Epub 2005 Nov 29.PMID: 16317080 [PubMed - indexed for MEDLINE]Related articlesFree article

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