PubMed

Hypothalamic inflammation and energy homeostasis: Resolving the paradox.

Thaler JP, Choi SJ, Schwartz MW, Wisse BE.

Front Neuroendocrinol. 2009 Oct 12. [Epub ahead of print]PMID: 19822168 [PubMed - as supplied by publisher]Related articles

Atypical Protein Kinase C Activity in the Hypothalamus Is Required for Lipopolysaccharide-Mediated Sickness Responses.

Thaler JP, Choi SJ, Sajan MP, Ogimoto K, Nguyen HT, Matsen M, Benoit SC, Wisse BE, Farese RV, Schwartz MW.

Endocrinology. 2009 Oct 9. [Epub ahead of print]PMID: 19819945 [PubMed - as supplied by publisher]Related articles

Does hypothalamic inflammation cause obesity?

Wisse BE, Schwartz MW.

Cell Metab. 2009 Oct;10(4):241-2.PMID: 19808014 [PubMed - in process]Related articles

Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A.

Enns LC, Morton JF, Mangalindan RS, McKnight GS, Schwartz MW, Kaeberlein MR, Kennedy BK, Rabinovitch PS, Ladiges WC.

J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1221-31. Epub 2009 Sep 23.PMID: 19776218 [PubMed - in process]Related articlesFree article

Academic Research Training for a Nonacademic Workplace: a Case Study of Graduate Student Alumni Who Work in Conservation.

Muir MJ, Schwartz MW.

Conserv Biol. 2009 Sep 16. [Epub ahead of print]PMID: 19758390 [PubMed - as supplied by publisher]Related articles

Hindbrain leptin receptor stimulation enhances the anorexic response to cholecystokinin.

Williams DL, Baskin DG, Schwartz MW.

Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1238-46. Epub 2009 Sep 2.PMID: 19726710 [PubMed - in process]Related articles

A global synthesis of plant extinction rates in urban areas.

Hahs AK, McDonnell MJ, McCarthy MA, Vesk PA, Corlett RT, Norton BA, Clemants SE, Duncan RP, Thompson K, Schwartz MW, Williams NS.

Ecol Lett. 2009 Nov;12(11):1165-73. Epub 2009 Aug 31.PMID: 19723284 [PubMed - in process]Related articles

The precautionary principle in managed relocation is misguided advice.

Schwartz MW, Hellmann JJ, McLachlan JS.

Trends Ecol Evol. 2009 Sep;24(9):474; author reply 476-7. No abstract available. PMID: 19595477 [PubMed - indexed for MEDLINE]Related articles

Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve.

German J, Kim F, Schwartz GJ, Havel PJ, Rhodes CJ, Schwartz MW, Morton GJ.

Endocrinology. 2009 Oct;150(10):4502-11. Epub 2009 Jul 2.PMID: 19574396 [PubMed - indexed for MEDLINE]Related articles

Activation of NF-kappaB by palmitate in endothelial cells: a key role for NADPH oxidase-derived superoxide in response to TLR4 activation.

Maloney E, Sweet IR, Hockenbery DM, Pham M, Rizzo NO, Tateya S, Handa P, Schwartz MW, Kim F.

Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1370-5. Epub 2009 Jun 18.PMID: 19542021 [PubMed - indexed for MEDLINE]Related articles

Multidimensional evaluation of managed relocation.

Richardson DM, Hellmann JJ, McLachlan JS, Sax DF, Schwartz MW, Gonzalez P, Brennan EJ, Camacho A, Root TL, Sala OE, Schneider SH, Ashe DM, Clark JR, Early R, Etterson JR, Fielder ED, Gill JL, Minteer BA, Polasky S, Safford HD, Thompson AR, Vellend M.

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9721-4. Epub 2009 Jun 9.PMID: 19509337 [PubMed - indexed for MEDLINE]Related articlesFree article

Receptors for tumor necrosis factor-alpha play a protective role against obesity and alter adipose tissue macrophage status.

Pamir N, McMillen TS, Kaiyala KJ, Schwartz MW, LeBoeuf RC.

Endocrinology. 2009 Sep;150(9):4124-34. Epub 2009 May 28.PMID: 19477937 [PubMed - indexed for MEDLINE]Related articles

Activation in brain energy regulation and reward centers by food cues varies with choice of visual stimulus.

Schur EA, Kleinhans NM, Goldberg J, Buchwald D, Schwartz MW, Maravilla K.

Int J Obes (Lond). 2009 Jun;33(6):653-61. Epub 2009 Apr 14.PMID: 19365394 [PubMed - in process]Related articles

Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration.

Sweet IR, Gilbert M, Maloney E, Hockenbery DM, Schwartz MW, Kim F.

Diabetologia. 2009 May;52(5):921-31. Epub 2009 Feb 14.PMID: 19219423 [PubMed - indexed for MEDLINE]Related articles

Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet.

Posey KA, Clegg DJ, Printz RL, Byun J, Morton GJ, Vivekanandan-Giri A, Pennathur S, Baskin DG, Heinecke JW, Woods SC, Schwartz MW, Niswender KD.

Am J Physiol Endocrinol Metab. 2009 May;296(5):E1003-12. Epub 2008 Dec 30.PMID: 19116375 [PubMed - indexed for MEDLINE]Related articles

Forebrain melanocortin signaling enhances the hindbrain satiety response to CCK-8.

Blevins JE, Morton GJ, Williams DL, Caldwell DW, Bastian LS, Wisse BE, Schwartz MW, Baskin DG.

Am J Physiol Regul Integr Comp Physiol. 2009 Mar;296(3):R476-84. Epub 2008 Dec 24.PMID: 19109369 [PubMed - indexed for MEDLINE]Related articles

Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety.

Williams DL, Baskin DG, Schwartz MW.

Endocrinology. 2009 Apr;150(4):1680-7. Epub 2008 Dec 12.PMID: 19074583 [PubMed - indexed for MEDLINE]Related articles

Scientific societies in the 21st century: a membership crisis.

Schwartz MW, Hunter ML Jr, Boersma PD.

Conserv Biol. 2008 Oct;22(5):1087-9. No abstract available. PMID: 18954335 [PubMed - indexed for MEDLINE]Related articles

Expression of peroxisome proliferator-activated receptor-gamma in key neuronal subsets regulating glucose metabolism and energy homeostasis.

Sarruf DA, Yu F, Nguyen HT, Williams DL, Printz RL, Niswender KD, Schwartz MW.

Endocrinology. 2009 Feb;150(2):707-12. Epub 2008 Oct 9.PMID: 18845632 [PubMed - indexed for MEDLINE]Related articles

Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance.

Kim F, Pham M, Maloney E, Rizzo NO, Morton GJ, Wisse BE, Kirk EA, Chait A, Schwartz MW.

Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):1982-8. Epub 2008 Sep 4.PMID: 18772497 [PubMed - indexed for MEDLINE]Related articlesFree article

Deficiency of TNFalpha converting enzyme (TACE/ADAM17) causes a lean, hypermetabolic phenotype in mice.

Gelling RW, Yan W, Al-Noori S, Pardini A, Morton GJ, Ogimoto K, Schwartz MW, Dempsey PJ.

Endocrinology. 2008 Dec;149(12):6053-64. Epub 2008 Aug 7.PMID: 18687778 [PubMed - indexed for MEDLINE]Related articles

Quantifying plant population persistence in human-dominated landscapes.

Lawson DM, Lamar CK, Schwartz MW.

Conserv Biol. 2008 Aug;22(4):922-8. Epub 2008 Jun 9.PMID: 18544094 [PubMed - indexed for MEDLINE]Related articles

Increased lipid oxidation heralds diabetes onset in DR.lyp/lyp rats.

Akesson L, Gelling RW, Jensen R, Ogimoto K, Fuller JM, Pefley R, Manavi S, Lernmark A, Schwartz MW.

Exp Clin Endocrinol Diabetes. 2008 Aug;116(8):475-80. Epub 2008 May 9.PMID: 18465680 [PubMed - indexed for MEDLINE]Related articles

Immunocytochemistry and laser capture microdissection for real-time quantitative PCR identify hindbrain neurons activated by interaction between leptin and cholecystokinin.

Williams DL, Schwartz MW, Bastian LS, Blevins JE, Baskin DG.

J Histochem Cytochem. 2008 Mar;56(3):285-93. Epub 2007 Nov 26.PMID: 18040081 [PubMed - indexed for MEDLINE]Related articlesFree article

Physiology. An integrative view of obesity.

Wisse BE, Kim F, Schwartz MW.

Science. 2007 Nov 9;318(5852):928-9. No abstract available. PMID: 17991852 [PubMed - indexed for MEDLINE]Related articles

Evidence that lipopolysaccharide-induced anorexia depends upon central, rather than peripheral, inflammatory signals.

Wisse BE, Ogimoto K, Tang J, Harris MK Jr, Raines EW, Schwartz MW.

Endocrinology. 2007 Nov;148(11):5230-7. Epub 2007 Aug 2.PMID: 17673516 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity.

Kim F, Pham M, Luttrell I, Bannerman DD, Tupper J, Thaler J, Hawn TR, Raines EW, Schwartz MW.

Circ Res. 2007 Jun 8;100(11):1589-96. Epub 2007 May 3.PMID: 17478729 [PubMed - indexed for MEDLINE]Related articlesFree article

A framework for debate of assisted migration in an era of climate change.

McLachlan JS, Hellmann JJ, Schwartz MW.

Conserv Biol. 2007 Apr;21(2):297-302. No abstract available. PMID: 17391179 [PubMed - indexed for MEDLINE]Related articles

Central interleukin-1 (IL1) signaling is required for pharmacological, but not physiological, effects of leptin on energy balance.

Wisse BE, Ogimoto K, Morton GJ, Williams DL, Schwartz MW.

Brain Res. 2007 May 4;1144:101-6. Epub 2007 Jan 27.PMID: 17320056 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation.

Williams DL, Baskin DG, Schwartz MW.

Diabetes. 2006 Dec;55(12):3387-93.PMID: 17130484 [PubMed - indexed for MEDLINE]Related articlesFree article

Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.

Weydt P, Pineda VV, Torrence AE, Libby RT, Satterfield TF, Lazarowski ER, Gilbert ML, Morton GJ, Bammler TK, Strand AD, Cui L, Beyer RP, Easley CN, Smith AC, Krainc D, Luquet S, Sweet IR, Schwartz MW, La Spada AR.

Cell Metab. 2006 Nov;4(5):349-62. Epub 2006 Oct 19.PMID: 17055784 [PubMed - indexed for MEDLINE]Related articles

How conservation scientists can help develop social capital for biodiversity.

Schwartz MW.

Conserv Biol. 2006 Oct;20(5):1550-2. No abstract available. PMID: 17002774 [PubMed - indexed for MEDLINE]Related articles

Central nervous system control of food intake and body weight.

Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW.

Nature. 2006 Sep 21;443(7109):289-95. Review.PMID: 16988703 [PubMed - indexed for MEDLINE]Related articles

Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis.

Pardini AW, Nguyen HT, Figlewicz DP, Baskin DG, Williams DL, Kim F, Schwartz MW.

Brain Res. 2006 Sep 27;1112(1):169-78. Epub 2006 Aug 22.PMID: 16925984 [PubMed - indexed for MEDLINE]Related articles

Predicting extinctions as a result of climate change.

Schwartz MW, Iverson LR, Prasad AM, Matthews SN, O'Connor RJ.

Ecology. 2006 Jul;87(7):1611-5.PMID: 16922312 [PubMed - indexed for MEDLINE]Related articles

Using population count data to assess the effects of changing river flow on an endangered Riparian plant.

Thomson DM, Schwartz MW.

Conserv Biol. 2006 Aug;20(4):1132-42.PMID: 16922229 [PubMed - indexed for MEDLINE]Related articles

Signal transducer and activator of transcription (stat) binding sites but not stat3 are required for fasting-induced transcription of agouti-related protein messenger ribonucleic acid.

Kaelin CB, Gong L, Xu AW, Yao F, Hockman K, Morton GJ, Schwartz MW, Barsh GS, MacKenzie RG.

Mol Endocrinol. 2006 Oct;20(10):2591-602. Epub 2006 May 18.PMID: 16709597 [PubMed - indexed for MEDLINE]Related articlesFree article

The promise and the potential consequences of the global transport of mycorrhizal fungal inoculum.

Schwartz MW, Hoeksema JD, Gehring CA, Johnson NC, Klironomos JN, Abbott LK, Pringle A.

Ecol Lett. 2006 May;9(5):501-15.PMID: 16643296 [PubMed - indexed for MEDLINE]Related articles

Central nervous system regulation of food intake.

Schwartz MW.

Obesity (Silver Spring). 2006 Feb;14 Suppl 1:1S-8S. Review. No abstract available. PMID: 16642956 [PubMed - indexed for MEDLINE]Related articles

Insulin action in the brain contributes to glucose lowering during insulin treatment of diabetes.

Gelling RW, Morton GJ, Morrison CD, Niswender KD, Myers MG Jr, Rhodes CJ, Schwartz MW.

Cell Metab. 2006 Jan;3(1):67-73.PMID: 16399506 [PubMed - indexed for MEDLINE]Related articles

Determinants of insulin availability in parenteral nutrition solutions.

Christianson MA, Schwartz MW, Suzuki N.

JPEN J Parenter Enteral Nutr. 2006 Jan-Feb;30(1):6-9.PMID: 16387892 [PubMed - indexed for MEDLINE]Related articles

Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons.

Morton GJ, Gelling RW, Niswender KD, Morrison CD, Rhodes CJ, Schwartz MW.

Cell Metab. 2005 Dec;2(6):411-20.PMID: 16330326 [PubMed - indexed for MEDLINE]Related articles

Effects of hypothalamic neurodegeneration on energy balance.

Xu AW, Kaelin CB, Morton GJ, Ogimoto K, Stanhope K, Graham J, Baskin DG, Havel P, Schwartz MW, Barsh GS.

PLoS Biol. 2005 Dec;3(12):e415. Epub 2005 Nov 29.PMID: 16296893 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of hypothalamic interleukin-1beta (IL-1beta) in regulation of energy homeostasis by melanocortins.

Wisse BE, Ogimoto K, Schwartz MW.

Peptides. 2006 Feb;27(2):265-73. Epub 2005 Nov 7. Review.PMID: 16274848 [PubMed - indexed for MEDLINE]Related articles

Working with amnesia.

Schwartz MW.

Pediatr Case Rev. 2003 Jan;3(1):1-2. No abstract available. PMID: 16222133 [PubMed - indexed for MEDLINE]Related articles

Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults.

Fishel MA, Watson GS, Montine TJ, Wang Q, Green PS, Kulstad JJ, Cook DG, Peskind ER, Baker LD, Goldgaber D, Nie W, Asthana S, Plymate SR, Schwartz MW, Craft S.

Arch Neurol. 2005 Oct;62(10):1539-44.PMID: 16216936 [PubMed - indexed for MEDLINE]Related articles

Out of synch: Clock mutation causes obesity in mice.

Williams DL, Schwartz MW.

Cell Metab. 2005 Jun;1(6):355-6.PMID: 16054082 [PubMed - indexed for MEDLINE]Related articles

Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling.

Morrison CD, Morton GJ, Niswender KD, Gelling RW, Schwartz MW.

Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1051-7. Epub 2005 Jul 26.PMID: 16046456 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of IKKbeta by glucose is necessary and sufficient to impair insulin signaling and nitric oxide production in endothelial cells.

Kim F, Tysseling KA, Rice J, Gallis B, Haji L, Giachelli CM, Raines EW, Corson MA, Schwartz MW.

J Mol Cell Cardiol. 2005 Aug;39(2):327-34.PMID: 15978611 [PubMed - indexed for MEDLINE]Related articles

The melanocortin system as a central integrator of direct and indirect controls of food intake.

Williams DL, Schwartz MW.

Am J Physiol Regul Integr Comp Physiol. 2005 Jul;289(1):R2-3. Review. No abstract available. PMID: 15956761 [PubMed - indexed for MEDLINE]Related articles