PubMed

Synthesis and evaluation of a glibenclamide glucose-conjugate: a potential new lead compound for substituted glibenclamide derivatives as islet imaging agents.

Schneider S, Ueberberg S, Korobeynikov A, Schechinger W, Schwanstecher C, Schwanstecher M, Klein HH, Schirrmacher E.

Regul Pept. 2007 Mar 1;139(1-3):122-7. Epub 2007 Jan 10.PMID: 17222470 [PubMed - indexed for MEDLINE]Related articles

In vitro and in vivo evaluation of novel glibenclamide derivatives as imaging agents for the non-invasive assessment of the pancreatic islet cell mass in animals and humans.

Schneider S, Feilen PJ, Schreckenberger M, Schwanstecher M, Schwanstecher C, Buchholz HG, Thews O, Oberholzer K, Korobeynikov A, Bauman A, Comagic S, Piel M, Schirrmacher E, Shiue CY, Alavi AA, Bartenstein P, Rösch F, Weber MM, Klein HH, Schirrmacher R.

Exp Clin Endocrinol Diabetes. 2005 Jul;113(7):388-95.PMID: 16025400 [PubMed - indexed for MEDLINE]Related articles

Synthesis and in vitro evaluation of (S)-2-([11C]methoxy)-4-[3-methyl-1-(2-piperidine-1-yl-phenyl)-butyl-carbamoyl]-benzoic acid ([11C]methoxy-repaglinide): a potential beta-cell imaging agent.

Wängler B, Beck C, Shiue CY, Schneider S, Schwanstecher C, Schwanstecher M, Feilen PJ, Alavi A, Rösch F, Schirrmacher R.

Bioorg Med Chem Lett. 2004 Oct 18;14(20):5205-9.PMID: 15380228 [PubMed - indexed for MEDLINE]Related articles

Synthesis and evaluation of (S)-2-(2-[18F]fluoroethoxy)-4-([3-methyl-1-(2-piperidin-1-yl-phenyl)-butyl-carbamoyl]-methyl)-benzoic acid ([18F]repaglinide): a promising radioligand for quantification of pancreatic beta-cell mass with positron emission tomography (PET).

Wängler B, Schneider S, Thews O, Schirrmacher E, Comagic S, Feilen P, Schwanstecher C, Schwanstecher M, Shiue CY, Alavi A, Höhnemann S, Piel M, Rösch F, Schirrmacher R.

Nucl Med Biol. 2004 Jul;31(5):639-47.PMID: 15219283 [PubMed - indexed for MEDLINE]Related articles

Ca2+/calmodulin-dependent protein kinase II delta2 regulates gene expression of insulin in INS-1 rat insulinoma cells.

Osterhoff M, Möhlig M, Schwanstecher M, Seufert J, Ortmann J, Schatz H, Pfeiffer AF.

Cell Calcium. 2003 Mar;33(3):175-84.PMID: 12600804 [PubMed - indexed for MEDLINE]Related articles

The common single nucleotide polymorphism E23K in K(IR)6.2 sensitizes pancreatic beta-cell ATP-sensitive potassium channels toward activation through nucleoside diphosphates.

Schwanstecher C, Neugebauer B, Schulz M, Schwanstecher M.

Diabetes. 2002 Dec;51 Suppl 3:S363-7.PMID: 12475776 [PubMed - indexed for MEDLINE]Related articlesFree article

Nucleotide sensitivity of pancreatic ATP-sensitive potassium channels and type 2 diabetes.

Schwanstecher C, Schwanstecher M.

Diabetes. 2002 Dec;51 Suppl 3:S358-62. Review.PMID: 12475775 [PubMed - indexed for MEDLINE]Related articlesFree article

K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels.

Schwanstecher C, Meyer U, Schwanstecher M.

Diabetes. 2002 Mar;51(3):875-9.PMID: 11872696 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP4- mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites.

Markworth E, Schwanstecher C, Schwanstecher M.

Diabetes. 2000 Sep;49(9):1413-8.PMID: 10969823 [PubMed - indexed for MEDLINE]Related articlesFree article

Stoichiometry of potassium channel opener action.

Gross I, Toman A, Uhde I, Schwanstecher C, Schwanstecher M.

Mol Pharmacol. 1999 Dec;56(6):1370-3.PMID: 10570067 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural requirements of sulphonylureas and analogues for interaction with sulphonylurea receptor subtypes.

Meyer M, Chudziak F, Schwanstecher C, Schwanstecher M, Panten U.

Br J Pharmacol. 1999 Sep;128(1):27-34.PMID: 10498831 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of the potassium channel opener site on sulfonylurea receptors.

Uhde I, Toman A, Gross I, Schwanstecher C, Schwanstecher M.

J Biol Chem. 1999 Oct 1;274(40):28079-82.PMID: 10497157 [PubMed - indexed for MEDLINE]Related articlesFree article

Stoichiometry of sulfonylurea-induced ATP-sensitive potassium channel closure.

Dörschner H, Brekardin E, Uhde I, Schwanstecher C, Schwanstecher M.

Mol Pharmacol. 1999 Jun;55(6):1060-6.PMID: 10347249 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP-sensitive potassium channels.

Schwanstecher M, Schwanstecher C, Chudziak F, Panten U, Clement JP 4th, Gonzalez G, Aguilar-Bryan L, Bryan J.

Methods Enzymol. 1999;294:445-58. No abstract available. PMID: 9916242 [PubMed - indexed for MEDLINE]Related articles

Potassium channel openers require ATP to bind to and act through sulfonylurea receptors.

Schwanstecher M, Sieverding C, Dörschner H, Gross I, Aguilar-Bryan L, Schwanstecher C, Bryan J.

EMBO J. 1998 Oct 1;17(19):5529-35.PMID: 9755153 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of N-benzoyl-D-phenylalanine and related compounds with the sulphonylurea receptor of beta-cells.

Schwanstecher C, Meyer M, Schwanstecher M, Panten U.

Br J Pharmacol. 1998 Mar;123(6):1023-30.PMID: 9559882 [PubMed - indexed for MEDLINE]Related articlesFree article

Association and stoichiometry of K(ATP) channel subunits.

Clement JP 4th, Kunjilwar K, Gonzalez G, Schwanstecher M, Panten U, Aguilar-Bryan L, Bryan J.

Neuron. 1997 May;18(5):827-38.PMID: 9182806 [PubMed - indexed for MEDLINE]Related articles

Sulfonylurea receptors and mechanism of sulfonylurea action.

Panten U, Schwanstecher M, Schwanstecher C.

Exp Clin Endocrinol Diabetes. 1996;104(1):1-9. Review.PMID: 8750563 [PubMed - indexed for MEDLINE]Related articles

Interaction of fluorescein derivatives with sulfonylurea binding in insulin-secreting cells.

Schwanstecher M, Bachmann C, Löser S, Panten U.

Pharmacology. 1995 Mar;50(3):182-91.PMID: 7746835 [PubMed - indexed for MEDLINE]Related articles

Location of the sulphonylurea receptor at the cytoplasmic face of the beta-cell membrane.

Schwanstecher M, Schwanstecher C, Dickel C, Chudziak F, Moshiri A, Panten U.

Br J Pharmacol. 1994 Nov;113(3):903-11.PMID: 7858884 [PubMed - indexed for MEDLINE]Related articlesFree article

Photoaffinity labeling of the cerebral sulfonylurea receptor using a novel radioiodinated azidoglibenclamide analogue.

Schwanstecher M, Löser S, Chudziak F, Bachmann C, Panten U.

J Neurochem. 1994 Aug;63(2):698-708.PMID: 8035194 [PubMed - indexed for MEDLINE]Related articles

Inhibition of K+ channels and stimulation of insulin secretion by the sulfonylurea, glimepiride, in relation to its membrane binding in pancreatic islets.

Schwanstecher M, Mnner K, Panten U.

Pharmacology. 1994 Aug;49(2):105-11.PMID: 7972319 [PubMed - indexed for MEDLINE]Related articles

Identification of a 38-kDa high affinity sulfonylurea-binding peptide in insulin-secreting cells and cerebral cortex.

Schwanstecher M, Löser S, Chudziak F, Panten U.

J Biol Chem. 1994 Jul 8;269(27):17768-71.PMID: 8027029 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic and extrapancreatic sulfonylurea receptors.

Panten U, Schwanstecher M, Schwanstecher C.

Horm Metab Res. 1992 Dec;24(12):549-54. Review.PMID: 1478610 [PubMed - indexed for MEDLINE]Related articles

The binding properties of the particulate and solubilized sulfonylurea receptor from cerebral cortex are modulated by the Mg2+ complex of ATP.

Schwanstecher M, Schaupp U, Löser S, Panten U.

J Neurochem. 1992 Oct;59(4):1325-35.PMID: 1402884 [PubMed - indexed for MEDLINE]Related articles

The binding properties of the solubilized sulfonylurea receptor from a pancreatic B-cell line are modulated by the Mg(++)-complex of ATP.

Schwanstecher M, Behrends S, Brandt C, Panten U.

J Pharmacol Exp Ther. 1992 Aug;262(2):495-502.PMID: 1501109 [PubMed - indexed for MEDLINE]Related articles

Effect of MgATP on pinacidil-induced displacement of glibenclamide from the sulphonylurea receptor in a pancreatic beta-cell line and rat cerebral cortex.

Schwanstecher M, Brandt C, Behrends S, Schaupp U, Panten U.

Br J Pharmacol. 1992 Jun;106(2):295-301.PMID: 1393263 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenine nucleotide-induced inhibition of binding of sulphonylureas to their receptor in pancreatic islets.

Schwanstecher M, Löser S, Brandt C, Scheffer K, Rosenberger F, Panten U.

Br J Pharmacol. 1992 Mar;105(3):531-4.PMID: 1628141 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphate and thiophosphate group donating adenine and guanine nucleotides inhibit glibenclamide binding to membranes from pancreatic islets.

Schwanstecher M, Löser S, Rietze I, Panten U.

Naunyn Schmiedebergs Arch Pharmacol. 1991 Jan;343(1):83-9.PMID: 1903188 [PubMed - indexed for MEDLINE]Related articles

Control of insulin secretion by sulfonylureas, meglitinide and diazoxide in relation to their binding to the sulfonylurea receptor in pancreatic islets.

Panten U, Burgfeld J, Goerke F, Rennicke M, Schwanstecher M, Wallasch A, Zünkler BJ, Lenzen S.

Biochem Pharmacol. 1989 Apr 15;38(8):1217-29.PMID: 2650685 [PubMed - indexed for MEDLINE]Related articles

Glucose both inhibits and stimulates insulin secretion from isolated pancreatic islets exposed to maximally effective concentrations of sulfonylureas.

Panten U, Schwanstecher M, Wallasch A, Lenzen S.

Naunyn Schmiedebergs Arch Pharmacol. 1988 Oct;338(4):459-62.PMID: 3149719 [PubMed - indexed for MEDLINE]Related articles