PubMed

Retinal ganglion cells are primarily affected in an animal model of OPA1 associated autosomal dominant optic atrophy.

Heiduschka P, Schnichels S, Fuhrmann N, Hofmeister S, Schraermeyer U, Wissinger B, Alavi MV.

Invest Ophthalmol Vis Sci. 2009 Oct 15. [Epub ahead of print]PMID: 19834041 [PubMed - as supplied by publisher]Related articles

Ultrastructural analysis of the pigment dispersion syndrome in DBA/2J mice.

Schraermeyer M, Schnichels S, Julien S, Heiduschka P, Bartz-Schmidt KU, Schraermeyer U.

Graefes Arch Clin Exp Ophthalmol. 2009 Nov;247(11):1493-504. Epub 2009 Jul 30.PMID: 19641932 [PubMed - indexed for MEDLINE]Related articles

Immunohistochemical localisation of intravitreally injected bevacizumab at the posterior pole of the primate eye: implication for the treatment of retinal vein occlusion.

Julien S, Heiduschka P, Hofmeister S, Schraermeyer U.

Br J Ophthalmol. 2008 Oct;92(10):1424-8.PMID: 18815425 [PubMed - indexed for MEDLINE]Related articles

[Localisation of bevacizumab in the monkey retina after an intravitreal injection of Avastin]

Schraermeyer U, Heiduschka P, Bartz-Schmidt KU.

Ophthalmologe. 2009 Jul;106(7):619-24. German. PMID: 18781309 [PubMed - indexed for MEDLINE]Related articles

[Chances and risks of anti-VEGF therapy]

Ziemssen F, Heiduschka P, Peters S, Grisanti S, Schraermeyer U.

Klin Monbl Augenheilkd. 2008 Sep;225(9):770-8. Review. German. PMID: 18759208 [PubMed - indexed for MEDLINE]Related articles

A reproducible and quantifiable model of choroidal neovascularization induced by VEGF A165 after subretinal adenoviral gene transfer in the rabbit.

Julien S, Kreppel F, Beck S, Heiduschka P, Brito V, Schnichels S, Kochanek S, Schraermeyer U.

Mol Vis. 2008 Jul 30;14:1358-72.PMID: 18682809 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of visual function in pigmented and albino rats by electroretinography and visual evoked potentials.

Heiduschka P, Schraermeyer U.

Graefes Arch Clin Exp Ophthalmol. 2008 Nov;246(11):1559-73. Epub 2008 Jul 25.PMID: 18654793 [PubMed - indexed for MEDLINE]Related articles

Immunohistochemical localisation of intravitreally injected bevacizumab in the anterior chamber angle, iris and ciliary body of the primate eye.

Peters S, Heiduschka P, Julien S, Bartz-Schmidt KU, Schraermeyer U.

Br J Ophthalmol. 2008 Apr;92(4):541-4. Epub 2008 Jan 22.PMID: 18211933 [PubMed - indexed for MEDLINE]Related articles

UV-A induced oxidative stress is more prominent in naturally pigmented aged human RPE cells compared to non-pigmented human RPE cells independent of zinc treatment.

Biesemeier A, Kokkinou D, Julien S, Heiduschka P, Berneburg M, Bartz-Schmidt KU, Schraermeyer U.

J Photochem Photobiol B. 2008 Feb 27;90(2):113-20. Epub 2007 Dec 4.PMID: 18203614 [PubMed - indexed for MEDLINE]Related articles

Bevacizumab (avastin) does not harm retinal function after intravitreal injection as shown by electroretinography in adult mice.

Heiduschka P, Julien S, Hofmeister S, Bartz-Schmidt KU, Schraermeyer U.

Retina. 2008 Jan;28(1):46-55.PMID: 18185137 [PubMed - indexed for MEDLINE]Related articles

Melanin precursor 5,6-dihydroxyindol: protective effects and cytotoxicity on retinal cells in vitro and in vivo.

Heiduschka P, Blitgen-Heinecke P, Tura A, Kokkinou D, Julien S, Hofmeister S, Bartz-Schmidt KU, Schraermeyer U.

Toxicol Pathol. 2007;35(7):1030-8.PMID: 18098047 [PubMed - indexed for MEDLINE]Related articles

Re: development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration.

Ziemssen F, Heiduschka P, Schraermeyer U; Tübingen Bevacizumab Study Group.

Retina. 2007 Oct;27(8):1154-6; author reply 1156-8. No abstract available. PMID: 18040264 [PubMed - indexed for MEDLINE]Related articles

Gene expression of the repulsive guidance molecules/neogenin in the developing and mature mouse visual system: C57BL/6J vs. the glaucoma model DBA/2J.

Schnichels S, Conrad S, Warstat K, Henke-Fahle S, Skutella T, Schraermeyer U, Julien S.

Gene Expr Patterns. 2007 Dec;8(1):1-11. Epub 2007 Sep 18.PMID: 17942375 [PubMed - indexed for MEDLINE]Related articles

Penetration of bevacizumab through the retina after intravitreal injection in the monkey.

Heiduschka P, Fietz H, Hofmeister S, Schultheiss S, Mack AF, Peters S, Ziemssen F, Niggemann B, Julien S, Bartz-Schmidt KU, Schraermeyer U; Tübingen Bevacizumab Study Group.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2814-23.PMID: 17525217 [PubMed - indexed for MEDLINE]Related articlesFree article

Ultrastructural findings in the primate eye after intravitreal injection of bevacizumab.

Peters S, Heiduschka P, Julien S, Ziemssen F, Fietz H, Bartz-Schmidt KU; Tübingen Bevacizumab Study Group, Schraermeyer U.

Am J Ophthalmol. 2007 Jun;143(6):995-1002. Epub 2007 Apr 23.PMID: 17449002 [PubMed - indexed for MEDLINE]Related articles

An overview on the toxic morphological changes in the retinal pigment epithelium after systemic compound administration.

Mecklenburg L, Schraermeyer U.

Toxicol Pathol. 2007;35(2):252-67. Review.PMID: 17366319 [PubMed - indexed for MEDLINE]Related articles

Comparative antiproliferative and cytotoxic profile of bevacizumab (Avastin), pegaptanib (Macugen) and ranibizumab (Lucentis) on different ocular cells.

Spitzer MS, Yoeruek E, Sierra A, Wallenfels-Thilo B, Schraermeyer U, Spitzer B, Bartz-Schmidt KU, Szurman P.

Graefes Arch Clin Exp Ophthalmol. 2007 Dec;245(12):1837-42. Epub 2007 Mar 9.PMID: 17347807 [PubMed - indexed for MEDLINE]Related articles

Tyrosinase biosynthesis and trafficking in adult human retinal pigment epithelial cells.

Julien S, Kociok N, Kreppel F, Kopitz J, Kochanek S, Biesemeier A, Blitgen-Heinecke P, Heiduschka P, Schraermeyer U.

Graefes Arch Clin Exp Ophthalmol. 2007 Oct;245(10):1495-505. Epub 2007 Feb 21.PMID: 17318568 [PubMed - indexed for MEDLINE]Related articles

A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy.

Alavi MV, Bette S, Schimpf S, Schuettauf F, Schraermeyer U, Wehrl HF, Ruttiger L, Beck SC, Tonagel F, Pichler BJ, Knipper M, Peters T, Laufs J, Wissinger B.

Brain. 2007 Apr;130(Pt 4):1029-42. Epub 2007 Feb 21.PMID: 17314202 [PubMed - indexed for MEDLINE]Related articlesFree article

Antipermeability and antiproliferative effects of standard and frozen bevacizumab on choroidal endothelial cells.

Peters S, Julien S, Heiduschka P, Grisanti S, Ziemssen F, Adler M, Schraermeyer U, Bartz-Schmidt KU.

Br J Ophthalmol. 2007 Jun;91(6):827-31. Epub 2006 Dec 19.PMID: 17179166 [PubMed - indexed for MEDLINE]Related articles

Ultrastructural changes after artificial retinal detachment with modified retinal adhesion.

Szurman P, Roters S, Grisanti S, Aisenbrey S, Schraermeyer U, Lüke M, Bartz-Schmidt KU, Thumann G.

Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4983-9.PMID: 17065517 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirally transduced bone marrow stromal cells differentiate into pigment epithelial cells and induce rescue effects in RCS rats.

Arnhold S, Heiduschka P, Klein H, Absenger Y, Basnaoglu S, Kreppel F, Henke-Fahle S, Kochanek S, Bartz-Schmidt KU, Addicks K, Schraermeyer U.

Invest Ophthalmol Vis Sci. 2006 Sep;47(9):4121-9.PMID: 16936132 [PubMed - indexed for MEDLINE]Related articlesFree article

Transplantation of bone marrow-derived mesenchymal stem cells rescue photoreceptor cells in the dystrophic retina of the rhodopsin knockout mouse.

Arnhold S, Absenger Y, Klein H, Addicks K, Schraermeyer U.

Graefes Arch Clin Exp Ophthalmol. 2007 Mar;245(3):414-22. Epub 2006 Aug 4.PMID: 16896916 [PubMed - indexed for MEDLINE]Related articles

Melanin protects choroidal blood vessels against light toxicity.

Peters S, Lamah T, Kokkinou D, Bartz-Schmidt KU, Schraermeyer U.

Z Naturforsch C. 2006 May-Jun;61(5-6):427-33.PMID: 16869503 [PubMed - indexed for MEDLINE]Related articles

Tyrosinase biosynthesis in adult mammalian retinal pigment epithelial cells.

Schraermeyer U, Kopitz J, Peters S, Henke-Fahle S, Blitgen-Heinecke P, Kokkinou D, Schwarz T, Bartz-Schmidt KU.

Exp Eye Res. 2006 Aug;83(2):315-21. Epub 2006 Mar 31.PMID: 16579986 [PubMed - indexed for MEDLINE]Related articles

Quantitative chemical analysis of ocular melanosomes in the TEM.

Eibl O, Schultheiss S, Blitgen-Heinecke P, Schraermeyer U.

Micron. 2006;37(3):262-76. Epub 2005 Sep 21.PMID: 16364648 [PubMed - indexed for MEDLINE]Related articles

Inhibition of lysosomal degradation in retinal pigment epithelium cells induces exocytosis of phagocytic residual material at the basolateral plasma membrane.

Peters S, Reinthal E, Blitgen-Heinecke P, Bartz-Schmidt KU, Schraermeyer U.

Ophthalmic Res. 2006;38(2):83-8. Epub 2005 Dec 12.PMID: 16352920 [PubMed - indexed for MEDLINE]Related articles

Zinc uptake and storage: the role of fundus pigmentation.

Kokkinou D, Kasper HU, Schwarz T, Bartz-Schmidt KU, Schraermeyer U.

Graefes Arch Clin Exp Ophthalmol. 2005 Oct;243(10):1050-5. Epub 2005 Oct 20.PMID: 15906061 [PubMed - indexed for MEDLINE]Related articles

Neurally selected embryonic stem cells induce tumor formation after long-term survival following engraftment into the subretinal space.

Arnhold S, Klein H, Semkova I, Addicks K, Schraermeyer U.

Invest Ophthalmol Vis Sci. 2004 Dec;45(12):4251-5.PMID: 15557428 [PubMed - indexed for MEDLINE]Related articlesFree article

The pigmentation of human iris influences the uptake and storing of zinc.

Kokkinou D, Kasper HU, Bartz-Schmidt KU, Schraermeyer U.

Pigment Cell Res. 2004 Oct;17(5):515-8.PMID: 15357838 [PubMed - indexed for MEDLINE]Related articles

A central role for inflammation in the pathogenesis of diabetic retinopathy.

Joussen AM, Poulaki V, Le ML, Koizumi K, Esser C, Janicki H, Schraermeyer U, Kociok N, Fauser S, Kirchhof B, Kern TS, Adamis AP.

FASEB J. 2004 Sep;18(12):1450-2. Epub 2004 Jul 1.PMID: 15231732 [PubMed - indexed for MEDLINE]Related articlesFree article

Iris pigment epithelial cells: a possible cell source for the future treatment of neurodegenerative diseases.

Arnhold S, Semkova I, Andressen C, Lenartz D, Meissner G, Sturm V, Kochanek S, Addicks K, Schraermeyer U.

Exp Neurol. 2004 Jun;187(2):410-7.PMID: 15144867 [PubMed - indexed for MEDLINE]Related articles

Investigation of laser-induced choroidal neovascularization in the rat.

Semkova I, Peters S, Welsandt G, Janicki H, Jordan J, Schraermeyer U.

Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5349-54.PMID: 14638737 [PubMed - indexed for MEDLINE]Related articlesFree article

An example of neural plasticity evoked by putative behavioral demand and early use of vibrissal hairs after facial nerve transection.

Tomov TL, Guntinas-Lichius O, Grosheva M, Streppel M, Schraermeyer U, Neiss WF, Angelov DN.

Exp Neurol. 2002 Dec;178(2):207-18.PMID: 12504880 [PubMed - indexed for MEDLINE]Related articles

Autologous transplantation of genetically modified iris pigment epithelial cells: a promising concept for the treatment of age-related macular degeneration and other disorders of the eye.

Semkova I, Kreppel F, Welsandt G, Luther T, Kozlowski J, Janicki H, Kochanek S, Schraermeyer U.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13090-5. Epub 2002 Sep 18.PMID: 12239351 [PubMed - indexed for MEDLINE]Related articlesFree article

Ultrastructural localization of light-induced lipid peroxides.

Kayatz P, Thumann G, Schraermeyer U.

Methods Enzymol. 2002;352:378-91. No abstract available. PMID: 12125365 [PubMed - indexed for MEDLINE]Related articles

Vitreous treatment of cultured human RPE cells results in differential expression of 10 new genes.

Kociok N, Hueber A, Esser P, Schraermeyer U, Thumann G, Luther TT, Jordan J, Welsandt G, Kirchhof B.

Invest Ophthalmol Vis Sci. 2002 Jul;43(7):2474-80.PMID: 12091453 [PubMed - indexed for MEDLINE]Related articlesFree article

Iris pigment epithelial cells transplanted into the vitreous accumulate at the optic nerve head.

Jordan JF, Semkova I, Kociok N, Welsandt GR, Krieglstein GK, Schraermeyer U.

Graefes Arch Clin Exp Ophthalmol. 2002 May;240(5):403-7. Epub 2002 Mar 20.PMID: 12073064 [PubMed - indexed for MEDLINE]Related articles

Long-term transgene expression in the RPE after gene transfer with a high-capacity adenoviral vector.

Kreppel F, Luther TT, Semkova I, Schraermeyer U, Kochanek S.

Invest Ophthalmol Vis Sci. 2002 Jun;43(6):1965-70.PMID: 12037006 [PubMed - indexed for MEDLINE]Related articlesFree article

Subretinally transplanted embryonic stem cells rescue photoreceptor cells from degeneration in the RCS rats.

Schraermeyer U, Thumann G, Luther T, Kociok N, Armhold S, Kruttwig K, Andressen C, Addicks K, Bartz-Schmidt KU.

Cell Transplant. 2001;10(8):673-80.PMID: 11814109 [PubMed - indexed for MEDLINE]Related articles

[Characteristics and functions of melanin in retinal pigment epithelium]

Peters S, Schraermeyer U.

Ophthalmologe. 2001 Dec;98(12):1181-5. Review. German. PMID: 11799902 [PubMed - indexed for MEDLINE]Related articles

Transplantation of iris pigment epithelium into the choroid slows down the degeneration of photoreceptors in the RCS rat.

Schraermeyer U, Kayatz P, Thumann G, Luther TT, Szurman P, Kociok N, Bartz-Schmidt KU.

Graefes Arch Clin Exp Ophthalmol. 2000 Dec;238(12):979-84.PMID: 11196361 [PubMed - indexed for MEDLINE]Related articles

Oxidation causes melanin fluorescence.

Kayatz P, Thumann G, Luther TT, Jordan JF, Bartz-Schmidt KU, Esser PJ, Schraermeyer U.

Invest Ophthalmol Vis Sci. 2001 Jan;42(1):241-6.PMID: 11133875 [PubMed - indexed for MEDLINE]Related articlesFree article

Multidrug resistance-associated proteins in glaucoma surgery.

Esser J, Esser P, Mietz H, Hueber A, Kociok N, Schraermeyer U, Krieglstein GK.

Graefes Arch Clin Exp Ophthalmol. 2000 Sep;238(9):727-32.PMID: 11045339 [PubMed - indexed for MEDLINE]Related articles

Transplantation of autologous iris pigment epithelium after removal of choroidal neovascular membranes.

Thumann G, Aisenbrey S, Schraermeyer U, Lafaut B, Esser P, Walter P, Bartz-Schmidt KU.

Arch Ophthalmol. 2000 Oct;118(10):1350-5.PMID: 11030816 [PubMed - indexed for MEDLINE]Related articles

Subretinal injection of rod outer segments leads to an increase in the number of early-stage melanosomes in retinal pigment epithelial cells.

Peters S, Kayatz P, Heimann K, Schraermeyer U.

Ophthalmic Res. 2000 Mar-Jun;32(2-3):52-6.PMID: 10754434 [PubMed - indexed for MEDLINE]Related articles

Detection of mRNA for proteins involved in retinol metabolism in iris pigment epithelium.

Thumann G, Kociok N, Bartz-Schmidt KU, Esser P, Schraermeyer U, Heimann K.

Graefes Arch Clin Exp Ophthalmol. 1999 Dec;237(12):1046-51.PMID: 10654176 [PubMed - indexed for MEDLINE]Related articles

Cellular transport of subretinal material into choroidal and scleral blood vessels: an electron microscopic study.

Peters S, Kayatz P, Kociok N, Heimann K, Schraermeyer U.

Graefes Arch Clin Exp Ophthalmol. 1999 Dec;237(12):976-83.PMID: 10654166 [PubMed - indexed for MEDLINE]Related articles

Comparative study of ROS degradation by IPE and RPE cells in vitro.

Dintelmann TS, Heimann K, Kayatz P, Schraermeyer U.

Graefes Arch Clin Exp Ophthalmol. 1999 Oct;237(10):830-9.PMID: 10502058 [PubMed - indexed for MEDLINE]Related articles

Ultrastructural localization of light-induced lipid peroxides in the rat retina.

Kayatz P, Heimann K, Schraermeyer U.

Invest Ophthalmol Vis Sci. 1999 Sep;40(10):2314-21.PMID: 10476798 [PubMed - indexed for MEDLINE]Related articlesFree article