PubMed

Human recombinant angiotensin converting enzyme 2 reduces the progression of diabetic nephropathy.

Oudit GY, Liu GC, Zhong J, Basu R, Chow FL, Zhou J, Loibner H, Janzek E, Schuster M, Penninger JM, Herzenberg AM, Kassiri Z, Scholey JW.

Diabetes. 2009 Nov 23. [Epub ahead of print]PMID: 19934006 [PubMed - as supplied by publisher]

INFLUENCE OF GLUCOSAMINE ON GLOMERULAR MESEANGIAL CELL TURNOVER: IMPLICATIONS FOR HYPERGLYCEMIA AND HEXOSAMINE PATHWAY FLUX.

James LR, Le C, Scholey JW.

Am J Physiol Endocrinol Metab. 2009 Nov 10. [Epub ahead of print]PMID: 19903862 [PubMed - as supplied by publisher]Related articles

The Effect of Direct Renin Inhibition on Renal Hemodynamic Function, Arterial Stiffness and Endothelial Function in Humans with Uncomplicated Type 1 Diabetes Mellitus: A Pilot Study.

Cherney DZ, Lai V, Scholey JW, Miller JA, Zinman B, Reich HN.

Diabetes Care. 2009 Nov 4. [Epub ahead of print]PMID: 19889802 [PubMed - as supplied by publisher]Related articles

Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction.

Kassiri Z, Zhong J, Guo D, Basu R, Wang X, Liu PP, Scholey JW, Penninger JM, Oudit GY.

Circ Heart Fail. 2009 Sep;2(5):446-55. Epub 2009 Jun 15.PMID: 19808375 [PubMed - indexed for MEDLINE]Related articles

Loss of TIMP3 enhances interstitial nephritis and fibrosis.

Kassiri Z, Oudit GY, Kandalam V, Awad A, Wang X, Ziou X, Maeda N, Herzenberg AM, Scholey JW.

J Am Soc Nephrol. 2009 Jun;20(6):1223-35. Epub 2009 Apr 30.PMID: 19406980 [PubMed - indexed for MEDLINE]Related articles

The role of ACE2 in pulmonary diseases--relevance for the nephrologist.

Oudit GY, Imai Y, Kuba K, Scholey JW, Penninger JM.

Nephrol Dial Transplant. 2009 May;24(5):1362-5. Epub 2009 Feb 19. No abstract available. PMID: 19228756 [PubMed - indexed for MEDLINE]Related articles

Endothelial nitric oxide synthase gene polymorphisms and the renal hemodynamic response to L-arginine.

Cherney DZ, Scholey JW, Zhou J, Zimpelmann J, Kennedy C, Burns KD, Lai V, Miller JA.

Kidney Int. 2009 Feb;75(3):327-32. Epub 2008 Nov 26.PMID: 19037250 [PubMed - indexed for MEDLINE]Related articles

Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease.

Reich HN, Oudit GY, Penninger JM, Scholey JW, Herzenberg AM.

Kidney Int. 2008 Dec;74(12):1610-6. Epub 2008 Oct 1.PMID: 19034303 [PubMed - indexed for MEDLINE]Related articles

Insights into the regulation of renal hemodynamic function in diabetic mellitus.

Cherney DZ, Scholey JW, Miller JA.

Curr Diabetes Rev. 2008 Nov;4(4):280-90. Review.PMID: 18991597 [PubMed - indexed for MEDLINE]Related articles

Effect of protein kinase Cbeta inhibition on renal hemodynamic function and urinary biomarkers in humans with type 1 diabetes: a pilot study.

Cherney DZ, Konvalinka A, Zinman B, Diamandis EP, Soosaipillai A, Reich H, Lorraine J, Lai V, Scholey JW, Miller JA.

Diabetes Care. 2009 Jan;32(1):91-3. Epub 2008 Oct 22.PMID: 18945921 [PubMed - in process]Related articlesFree article

Renal hemodynamic effect of cyclooxygenase 2 inhibition in young men and women with uncomplicated type 1 diabetes mellitus.

Cherney DZ, Scholey JW, Nasrallah R, Dekker MG, Slorach C, Bradley TJ, Hébert RL, Sochett EB, Miller JA.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1336-41. Epub 2008 Apr 9.PMID: 18400871 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress.

Oudit GY, Kassiri Z, Zhou J, Liu QC, Liu PP, Backx PH, Dawood F, Crackower MA, Scholey JW, Penninger JM.

Cardiovasc Res. 2008 Jun 1;78(3):505-14. Epub 2008 Feb 15.PMID: 18281373 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of sex in primary glomerulonephritis.

Cattran DC, Reich HN, Beanlands HJ, Miller JA, Scholey JW, Troyanov S; Genes, Gender and Glomerulonephritis Group.

Nephrol Dial Transplant. 2008 Jul;23(7):2247-53. Epub 2008 Jan 8.PMID: 18182409 [PubMed - indexed for MEDLINE]Related articles

The effect of cyclooxygenase-2 inhibition on renal hemodynamic function in humans with type 1 diabetes.

Cherney DZ, Miller JA, Scholey JW, Bradley TJ, Slorach C, Curtis JR, Dekker MG, Nasrallah R, Hébert RL, Sochett EB.

Diabetes. 2008 Mar;57(3):688-95. Epub 2007 Dec 14.PMID: 18083781 [PubMed - indexed for MEDLINE]Related articlesFree article

Remission of proteinuria improves prognosis in IgA nephropathy.

Reich HN, Troyanov S, Scholey JW, Cattran DC; Toronto Glomerulonephritis Registry.

J Am Soc Nephrol. 2007 Dec;18(12):3177-83. Epub 2007 Oct 31.PMID: 17978307 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of oral contraceptives on the nitric oxide system and renal function.

Cherney DZ, Scholey JW, Cattran DC, Kang AK, Zimpelmann J, Kennedy C, Lai V, Burns KD, Miller JA.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1539-44. Epub 2007 Aug 22.PMID: 17715260 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury.

Wong DW, Oudit GY, Reich H, Kassiri Z, Zhou J, Liu QC, Backx PH, Penninger JM, Herzenberg AM, Scholey JW.

Am J Pathol. 2007 Aug;171(2):438-51. Epub 2007 Jun 28.PMID: 17600118 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.

Oudit GY, Kassiri Z, Patel MP, Chappell M, Butany J, Backx PH, Tsushima RG, Scholey JW, Khokha R, Penninger JM.

Cardiovasc Res. 2007 Jul 1;75(1):29-39. Epub 2007 Apr 21.PMID: 17499227 [PubMed - indexed for MEDLINE]Related articlesFree article

Homocysteine induces mesangial cell apoptosis via activation of p38-mitogen-activated protein kinase.

Shastry S, Ingram AJ, Scholey JW, James LR.

Kidney Int. 2007 Feb;71(4):304-11. Epub 2006 Dec 6.PMID: 17149372 [PubMed - indexed for MEDLINE]Related articles

Gender differences in the renal response to renin-angiotensin system blockade.

Miller JA, Cherney DZ, Duncan JA, Lai V, Burns KD, Kennedy CR, Zimpelmann J, Gao W, Cattran DC, Scholey JW.

J Am Soc Nephrol. 2006 Sep;17(9):2554-60. Epub 2006 Aug 16.PMID: 16914541 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis.

Oudit GY, Herzenberg AM, Kassiri Z, Wong D, Reich H, Khokha R, Crackower MA, Backx PH, Penninger JM, Scholey JW.

Am J Pathol. 2006 Jun;168(6):1808-20.PMID: 16723697 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of renin angiotensin system modulation on the hyperfiltration state in type 1 diabetes.

Sochett EB, Cherney DZ, Curtis JR, Dekker MG, Scholey JW, Miller JA.

J Am Soc Nephrol. 2006 Jun;17(6):1703-9. Epub 2006 May 3.PMID: 16672313 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial nitric oxide synthase gene/gender interactions and the renal hemodynamic response to angiotensin II.

Page A, Reich H, Zhou J, Lai V, Cattran DC, Scholey JW, Miller JA.

J Am Soc Nephrol. 2005 Oct;16(10):3053-60. Epub 2005 Aug 10.PMID: 16093452 [PubMed - indexed for MEDLINE]Related articlesFree article

Albumin activates ERK via EGF receptor in human renal epithelial cells.

Reich H, Tritchler D, Herzenberg AM, Kassiri Z, Zhou X, Gao W, Scholey JW.

J Am Soc Nephrol. 2005 May;16(5):1266-78. Epub 2005 Apr 13.PMID: 15829704 [PubMed - indexed for MEDLINE]Related articlesFree article

Focal and segmental glomerulosclerosis: definition and relevance of a partial remission.

Troyanov S, Wall CA, Miller JA, Scholey JW, Cattran DC; Toronto Glomerulonephritis Registry Group.

J Am Soc Nephrol. 2005 Apr;16(4):1061-8. Epub 2005 Feb 16.PMID: 15716334 [PubMed - indexed for MEDLINE]Related articlesFree article

Troponin I and T levels in renal failure patients without acute coronary syndrome: a systematic review of the literature.

Needham DM, Shufelt KA, Tomlinson G, Scholey JW, Newton GE.

Can J Cardiol. 2004 Oct;20(12):1212-8. Review.PMID: 15494773 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel in vivo lecithin-cholesterol acyltransferase (LCAT)-deficient mouse expressing predominantly LpX is associated with spontaneous glomerulopathy.

Zhu X, Herzenberg AM, Eskandarian M, Maguire GF, Scholey JW, Connelly PW, Ng DS.

Am J Pathol. 2004 Oct;165(4):1269-78.PMID: 15466392 [PubMed - indexed for MEDLINE]Related articlesFree article

Idiopathic membranous nephropathy: definition and relevance of a partial remission.

Troyanov S, Wall CA, Miller JA, Scholey JW, Cattran DC; Toronto Glomerulonephritis Registry Group.

Kidney Int. 2004 Sep;66(3):1199-205.PMID: 15327418 [PubMed - indexed for MEDLINE]Related articles

Activation of mesangial cell MAPK in response to homocysteine.

Ingram AJ, Krepinsky JC, James L, Austin RC, Tang D, Salapatek AM, Thai K, Scholey JW.

Kidney Int. 2004 Aug;66(2):733-45.PMID: 15253728 [PubMed - indexed for MEDLINE]Related articles

The impact of renin-angiotensin system polymorphisms on physiological and pathophysiological processes in humans.

Miller JA, Scholey JW.

Curr Opin Nephrol Hypertens. 2004 Jan;13(1):101-6. Review.PMID: 15090866 [PubMed - indexed for MEDLINE]Related articles

Characterization of the PGI2/IP system in cultured rat mesangial cells.

Nasrallah R, Landry A, Scholey JW, Hébert RL.

Prostaglandins Leukot Essent Fatty Acids. 2004 May;70(5):455-64.PMID: 15062848 [PubMed - indexed for MEDLINE]Related articles

Effects of oral contraceptive use on the renal and systemic vascular response to angiotensin II infusion.

Ahmed SB, Kang AK, Burns KD, Kennedy CR, Lai V, Cattran DC, Scholey JW, Miller JA.

J Am Soc Nephrol. 2004 Mar;15(3):780-6.PMID: 14978181 [PubMed - indexed for MEDLINE]Related articlesFree article

Necrotizing glomerulonephritis caused by Bartonella henselae endocarditis.

Bookman I, Scholey JW, Jassal SV, Lajoie G, Herzenberg AM.

Am J Kidney Dis. 2004 Feb;43(2):e25-30.PMID: 14750122 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide inhibits stretch-induced MAPK activation in mesangial cells through RhoA inactivation.

Krepinsky JC, Ingram AJ, Tang D, Wu D, Liu L, Scholey JW.

J Am Soc Nephrol. 2003 Nov;14(11):2790-800.PMID: 14569089 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II and the glomerulus: focus on diabetic kidney disease.

Scholey JW.

Curr Hypertens Rep. 2003 Apr;5(2):172-80. Review.PMID: 12642018 [PubMed - indexed for MEDLINE]Related articles

Interactions between gender and the angiotensin type 1 receptor gene polymorphism.

Reich H, Duncan JA, Weinstein J, Cattran DC, Scholey JW, Miller JA.

Kidney Int. 2003 Apr;63(4):1443-9.PMID: 12631360 [PubMed - indexed for MEDLINE]Related articles

Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation.

James LR, Tang D, Ingram A, Ly H, Thai K, Cai L, Scholey JW.

Diabetes. 2002 Apr;51(4):1146-56.PMID: 11916938 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in the renin angiotensin system throughout the normal menstrual cycle.

Chidambaram M, Duncan JA, Lai VS, Cattran DC, Floras JS, Scholey JW, Miller JA.

J Am Soc Nephrol. 2002 Feb;13(2):446-52.PMID: 11805174 [PubMed - indexed for MEDLINE]Related articlesFree article

17beta -Estradiol modulates mechanical strain-induced MAPK activation in mesangial cells.

Krepinsky J, Ingram AJ, James L, Ly H, Thai K, Cattran DC, Miller JA, Scholey JW.

J Biol Chem. 2002 Mar 15;277(11):9387-94. Epub 2002 Jan 2.PMID: 11777903 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II activates the GFAT promoter in mesangial cells.

James LR, Ingram A, Ly H, Thai K, Cai L, Scholey JW.

Am J Physiol Renal Physiol. 2001 Jul;281(1):F151-62.PMID: 11399656 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II type 1 receptor gene polymorphisms in humans: physiology and pathophysiology of the genotypes.

Duncan JA, Scholey JW, Miller JA.

Curr Opin Nephrol Hypertens. 2001 Jan;10(1):111-6. Review.PMID: 11195043 [PubMed - indexed for MEDLINE]Related articles

Effect of oral contraceptives on the renin angiotensin system and renal function.

Kang AK, Duncan JA, Cattran DC, Floras JS, Lai V, Scholey JW, Miller JA.

Am J Physiol Regul Integr Comp Physiol. 2001 Mar;280(3):R807-13.PMID: 11171661 [PubMed - indexed for MEDLINE]Related articles

Effects of diabetes and hypertension on glomerular transforming growth factor-beta receptor expression.

Kang MJ, Ingram A, Ly H, Thai K, Scholey JW.

Kidney Int. 2000 Oct;58(4):1677-85.PMID: 11012901 [PubMed - indexed for MEDLINE]Related articlesFree article

Stretch activation of jun N-terminal kinase/stress-activated protein kinase in mesangial cells.

Ingram AJ, James L, Ly H, Thai K, Scholey JW.

Kidney Int. 2000 Oct;58(4):1431-9.PMID: 11012878 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of GFAT activates PAI-1 promoter in mesangial cells.

James LR, Fantus IG, Goldberg H, Ly H, Scholey JW.

Am J Physiol Renal Physiol. 2000 Oct;279(4):F718-27.PMID: 10997922 [PubMed - indexed for MEDLINE]Related articlesFree article

Stretch-induced mesangial cell ERK1/ERK2 activation is enhanced in high glucose by decreased dephosphorylation.

Dlugosz JA, Munk S, Kapor-Drezgic J, Goldberg HJ, Fantus IG, Scholey JW, Whiteside CI.

Am J Physiol Renal Physiol. 2000 Oct;279(4):F688-97.PMID: 10997919 [PubMed - indexed for MEDLINE]Related articlesFree article

NO inhibits stretch-induced MAPK activity by cytoskeletal disruption.

Ingram AJ, James L, Cai L, Thai K, Ly H, Scholey JW.

J Biol Chem. 2000 Dec 22;275(51):40301-6.PMID: 10984494 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide modulates stretch activation of mitogen-activated protein kinases in mesangial cells.

Ingram AJ, James L, Ly H, Thai K, Cai L, Scholey JW.

Kidney Int. 2000 Sep;58(3):1067-77.PMID: 10972671 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II type 1 receptor gene polymorphism and the response to hyperglycemia in early type 1 diabetes.

Miller JA, Thai K, Scholey JW.

Diabetes. 2000 Sep;49(9):1585-9.PMID: 10969844 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells.

Ingram AJ, James L, Thai K, Ly H, Cai L, Scholey JW.

Am J Physiol Renal Physiol. 2000 Aug;279(2):F243-51.PMID: 10919842 [PubMed - indexed for MEDLINE]Related articlesFree article