PubMed

Active HIF-1 in the Normal Human Retina.

Hughes JM, Groot AJ, van der Groep P, Sersansie R, Vooijs M, van Diest PJ, van Noorden CJ, Schlingemann RO, Klaassen I.

J Histochem Cytochem. 2009 Nov 9. [Epub ahead of print]PMID: 19901273 [PubMed - as supplied by publisher]Related articlesFree article

Treatment of retinal diseases with VEGF antagonists.

Schlingemann RO, Witmer AN.

Prog Brain Res. 2009;175:253-67. Review.PMID: 19660661 [PubMed - indexed for MEDLINE]Related articles

Altered expression of genes related to blood-retina barrier disruption in streptozotocin-induced diabetes.

Klaassen I, Hughes JM, Vogels IM, Schalkwijk CG, Van Noorden CJ, Schlingemann RO.

Exp Eye Res. 2009 Jun 15;89(1):4-15. Epub 2009 Jan 20.PMID: 19284967 [PubMed - indexed for MEDLINE]Related articles

Selective loss of inner retinal layer thickness in type 1 diabetic patients with minimal diabetic retinopathy.

van Dijk HW, Kok PH, Garvin M, Sonka M, Devries JH, Michels RP, van Velthoven ME, Schlingemann RO, Verbraak FD, Abràmoff MD.

Invest Ophthalmol Vis Sci. 2009 Jul;50(7):3404-9. Epub 2009 Jan 17.PMID: 19151397 [PubMed - indexed for MEDLINE]Related articles

The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy.

Kuiper EJ, Van Nieuwenhoven FA, de Smet MD, van Meurs JC, Tanck MW, Oliver N, Klaassen I, Van Noorden CJ, Goldschmeding R, Schlingemann RO.

PLoS One. 2008 Jul 16;3(7):e2675.PMID: 18628999 [PubMed - indexed for MEDLINE]Related articlesFree article

Connective tissue growth factor is necessary for retinal capillary basal lamina thickening in diabetic mice.

Kuiper EJ, van Zijderveld R, Roestenberg P, Lyons KM, Goldschmeding R, Klaassen I, Van Noorden CJ, Schlingemann RO.

J Histochem Cytochem. 2008 Aug;56(8):785-92. Epub 2008 May 12.PMID: 18474939 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes changes ionotropic glutamate receptor subunit expression level in the human retina.

Santiago AR, Hughes JM, Kamphuis W, Schlingemann RO, Ambrósio AF.

Brain Res. 2008 Mar 10;1198:153-9. Epub 2008 Feb 6.PMID: 18258217 [PubMed - indexed for MEDLINE]Related articles

The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1.

Jaalouk DE, Ozawa MG, Sun J, Lahdenranta J, Schlingemann RO, Pasqualini R, Arap W.

Cancer Res. 2007 Oct 15;67(20):9623-9.PMID: 17942890 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retina.

Kuiper EJ, Hughes JM, Van Geest RJ, Vogels IM, Goldschmeding R, Van Noorden CJ, Schlingemann RO, Klaassen I.

Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4267-76.PMID: 17724216 [PubMed - indexed for MEDLINE]Related articlesFree article

Guidance for the treatment of neovascular age-related macular degeneration.

Schmidt-Erfurth UM, Richard G, Augustin A, Aylward WG, Bandello F, Corcòstegui B, Cunha-Vaz J, Gaudric A, Leys A, Schlingemann RO; European Society for Retina Specialists' Guidelines Committee (EURETINA).

Acta Ophthalmol Scand. 2007 Aug;85(5):486-94. Review.PMID: 17655610 [PubMed - indexed for MEDLINE]Related articles

Angiogenesis is not impaired in connective tissue growth factor (CTGF) knock-out mice.

Kuiper EJ, Roestenberg P, Ehlken C, Lambert V, van Treslong-de Groot HB, Lyons KM, Agostini HJ, Rakic JM, Klaassen I, Van Noorden CJ, Goldschmeding R, Schlingemann RO.

J Histochem Cytochem. 2007 Nov;55(11):1139-47. Epub 2007 Jul 11.PMID: 17625227 [PubMed - indexed for MEDLINE]Related articlesFree article

[The practice guideline 'The red eye' (first revision) of the Dutch College of General Practitioners; a response from the perspective ofthe ophthalmologist]

Schlingemann RO, van der Meulen IJ, Nieuwendaal CP.

Ned Tijdschr Geneeskd. 2007 Jun 2;151(22):1219-21. Dutch. PMID: 17583088 [PubMed - indexed for MEDLINE]Related articles

Decreased optical coherence tomography-measured pericentral retinal thickness in patients with diabetes mellitus type 1 with minimal diabetic retinopathy.

Biallosterski C, van Velthoven ME, Michels RP, Schlingemann RO, DeVries JH, Verbraak FD.

Br J Ophthalmol. 2007 Sep;91(9):1135-8. Epub 2007 Mar 23.PMID: 17383994 [PubMed - indexed for MEDLINE]Related articles

Expression of vascular endothelial growth factor, stromal cell-derived factor-1, and CXCR4 in human limb muscle with acute and chronic ischemia.

van Weel V, Seghers L, de Vries MR, Kuiper EJ, Schlingemann RO, Bajema IM, Lindeman JH, Delis-van Diemen PM, van Hinsbergh VW, van Bockel JH, Quax PH.

Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1426-32. Epub 2007 Mar 15.PMID: 17363691 [PubMed - indexed for MEDLINE]Related articlesFree article

Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina.

Hughes JM, Kuiper EJ, Klaassen I, Canning P, Stitt AW, Van Bezu J, Schalkwijk CG, Van Noorden CJ, Schlingemann RO.

Diabetologia. 2007 May;50(5):1089-98. Epub 2007 Feb 28.PMID: 17333105 [PubMed - indexed for MEDLINE]Related articlesFree article

[Screening for diabetic retinopathy]

Hartstra WW, Holleman F, Hoekstra JB, Schlingemann RO.

Ned Tijdschr Geneeskd. 2007 Jan 27;151(4):228-33. Review. Dutch. PMID: 17323877 [PubMed - indexed for MEDLINE]Related articles

Association of connective tissue growth factor with fibrosis in vitreoretinal disorders in the human eye.

Kuiper EJ, de Smet MD, van Meurs JC, Tan HS, Tanck MW, Oliver N, van Nieuwenhoven FA, Goldschmeding R, Schlingemann RO.

Arch Ophthalmol. 2006 Oct;124(10):1457-62. Erratum in: Arch Ophthalmol. 2007 Feb;125(2):277. PMID: 17030714 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factor a in eyes with uveal melanoma.

Missotten GS, Notting IC, Schlingemann RO, Zijlmans HJ, Lau C, Eilers PH, Keunen JE, Jager MJ.

Arch Ophthalmol. 2006 Oct;124(10):1428-34.PMID: 17030710 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined en-face optical coherence tomography and confocal ophthalmoscopy findings in active multifocal and serpiginous chorioretinitis.

van Velthoven ME, Ongkosuwito JV, Verbraak FD, Schlingemann RO, de Smet MD.

Am J Ophthalmol. 2006 May;141(5):972-5.PMID: 16678527 [PubMed - indexed for MEDLINE]Related articles

Added value of OCT in evaluating the presence of leakage in patients with age-related macular degeneration treated with PDT.

van Velthoven ME, de Smet MD, Schlingemann RO, Magnani M, Verbraak FD.

Graefes Arch Clin Exp Ophthalmol. 2006 Sep;244(9):1119-23. Epub 2006 Mar 8.PMID: 16523305 [PubMed - indexed for MEDLINE]Related articles

Single spot PDT in patients with circumscribed choroidal haemangioma and near normal visual acuity.

Verbraak FD, Schlingemann RO, de Smet MD, Keunen JE.

Graefes Arch Clin Exp Ophthalmol. 2006 Sep;244(9):1178-82. Epub 2006 Feb 28.PMID: 16506074 [PubMed - indexed for MEDLINE]Related articles

Evaluation of central serous retinopathy with en face optical coherence tomography.

van Velthoven ME, Verbraak FD, Garcia PM, Schlingemann RO, Rosen RB, de Smet MD.

Br J Ophthalmol. 2005 Nov;89(11):1483-8.PMID: 16234458 [PubMed - indexed for MEDLINE]Related articlesFree article

START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease.

van Royen N, Schirmer SH, Atasever B, Behrens CY, Ubbink D, Buschmann EE, Voskuil M, Bot P, Hoefer I, Schlingemann RO, Biemond BJ, Tijssen JG, Bode C, Schaper W, Oskam J, Legemate DA, Piek JJ, Buschmann I.

Circulation. 2005 Aug 16;112(7):1040-6. Epub 2005 Aug 8.PMID: 16087795 [PubMed - indexed for MEDLINE]Related articlesFree article

Value of routine funduscopy in patients with hypertension: systematic review.

van den Born BJ, Hulsman CA, Hoekstra JB, Schlingemann RO, van Montfrans GA.

BMJ. 2005 Jul 9;331(7508):73. Review.PMID: 16002881 [PubMed - indexed for MEDLINE]Related articlesFree article

Spare the rod and spoil the eye.

Arden GB, Sidman RL, Arap W, Schlingemann RO.

Br J Ophthalmol. 2005 Jun;89(6):764-9. Review.PMID: 15923516 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunohistochemical localization of vascular endothelial growth factor receptors-1, -2 and -3 in human spinal cord: altered expression in amyotrophic lateral sclerosis.

Spliet WG, Aronica E, Ramkema M, Witmer AN, Schlingemann RO, de Jong JM, Troost D.

Neuropathol Appl Neurobiol. 2004 Aug;30(4):351-9.PMID: 15305980 [PubMed - indexed for MEDLINE]Related articles

Orbital irradiation for Graves' ophthalmopathy: Is it safe? A long-term follow-up study.

Wakelkamp IM, Tan H, Saeed P, Schlingemann RO, Verbraak FD, Blank LE, Prummel MF, Wiersinga WM.

Ophthalmology. 2004 Aug;111(8):1557-62.PMID: 15288988 [PubMed - indexed for MEDLINE]Related articles

Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina.

Kuiper EJ, Witmer AN, Klaassen I, Oliver N, Goldschmeding R, Schlingemann RO.

Br J Ophthalmol. 2004 Aug;88(8):1082-7.PMID: 15258030 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factor overexpression in ischemic skeletal muscle enhances myoglobin expression in vivo.

van Weel V, Deckers MM, Grimbergen JM, van Leuven KJ, Lardenoye JH, Schlingemann RO, van Nieuw Amerongen GP, van Bockel JH, van Hinsbergh VW, Quax PH.

Circ Res. 2004 Jul 9;95(1):58-66. Epub 2004 May 20.PMID: 15155530 [PubMed - indexed for MEDLINE]Related articlesFree article

Connective tissue growth factor is increased in plasma of type 1 diabetic patients with nephropathy.

Roestenberg P, van Nieuwenhoven FA, Wieten L, Boer P, Diekman T, Tiller AM, Wiersinga WM, Oliver N, Usinger W, Weitz S, Schlingemann RO, Goldschmeding R.

Diabetes Care. 2004 May;27(5):1164-70.PMID: 15111539 [PubMed - indexed for MEDLINE]Related articlesFree article

[Routine funduscopic examination in hypertensive patients not useful]

van den Born BJ, Schlingemann RO, Hoekstra JB, van Montfrans GA.

Ned Tijdschr Geneeskd. 2004 Mar 6;148(10):464-8. Review. Dutch. PMID: 15042890 [PubMed - indexed for MEDLINE]Related articles

Vascular leucocyte adhesion molecules unaltered in the human retina in diabetes.

Hughes JM, Brink A, Witmer AN, Hanraads-de Riemer M, Klaassen I, Schlingemann RO.

Br J Ophthalmol. 2004 Apr;88(4):566-72.PMID: 15031178 [PubMed - indexed for MEDLINE]Related articlesFree article

Aminopeptidase A is a functional target in angiogenic blood vessels.

Marchiò S, Lahdenranta J, Schlingemann RO, Valdembri D, Wesseling P, Arap MA, Hajitou A, Ozawa MG, Trepel M, Giordano RJ, Nanus DM, Dijkman HB, Oosterwijk E, Sidman RL, Cooper MD, Bussolino F, Pasqualini R, Arap W.

Cancer Cell. 2004 Feb;5(2):151-62.PMID: 14998491 [PubMed - indexed for MEDLINE]Related articles

Are tumours angiogenesis-dependent?

Verheul HM, Voest EE, Schlingemann RO.

J Pathol. 2004 Jan;202(1):5-13. Review.PMID: 14694516 [PubMed - indexed for MEDLINE]Related articles

In vivo angiogenic phenotype of endothelial cells and pericytes induced by vascular endothelial growth factor-A.

Witmer AN, van Blijswijk BC, van Noorden CJ, Vrensen GF, Schlingemann RO.

J Histochem Cytochem. 2004 Jan;52(1):39-52.PMID: 14688216 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of growth factors and the wound healing response in age-related macular degeneration.

Schlingemann RO.

Graefes Arch Clin Exp Ophthalmol. 2004 Jan;242(1):91-101. Epub 2003 Dec 18. Review.PMID: 14685874 [PubMed - indexed for MEDLINE]Related articles

Longstanding symptomatic choroidal hemangioma managed with limited PDT as initial or salvage therapy.

Verbraak FD, Schlingemann RO, Keunen JE, de Smet MD.

Graefes Arch Clin Exp Ophthalmol. 2003 Nov;241(11):891-8. Epub 2003 Oct 18.PMID: 14566571 [PubMed - indexed for MEDLINE]Related articles

Heat shock protein expression in the eye and in uveal melanoma.

Missotten GS, Journée-de Korver JG, de Wolff-Rouendaal D, Keunen JE, Schlingemann RO, Jager MJ.

Invest Ophthalmol Vis Sci. 2003 Jul;44(7):3059-65.PMID: 12824252 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factors and angiogenesis in eye disease.

Witmer AN, Vrensen GF, Van Noorden CJ, Schlingemann RO.

Prog Retin Eye Res. 2003 Jan;22(1):1-29. Review.PMID: 12597922 [PubMed - indexed for MEDLINE]Related articles

[Eye complaints indicative of a tumor elsewhere in the body]

Marinkovic M, van Lanschot JJ, Schlingemann RO, de Smet MD, Saeed P.

Ned Tijdschr Geneeskd. 2002 Dec 14;146(50):2393-6. Dutch. Erratum in: Ned Tijdschr Geneeskd. 2003 Dec 27;147(52):2612. Ned Tijdschr Geneeskd. 2003 Jan 18;147(3):136. PMID: 12518513 [PubMed - indexed for MEDLINE]Related articles

Blood-brain barrier integrity is unaltered in human brain cortex with diabetes mellitus.

Dai J, Vrensen GF, Schlingemann RO.

Brain Res. 2002 Nov 8;954(2):311-6.PMID: 12414115 [PubMed - indexed for MEDLINE]Related articles

[The practice guideline 'Refraction errors' from the Dutch College of General Practitioners: response from the perspective of ophthalmology]

Schlingemann RO, Brink HM, Völker-Dieben HJ.

Ned Tijdschr Geneeskd. 2002 Sep 21;146(38):1771-4. Dutch. PMID: 12369436 [PubMed - indexed for MEDLINE]Related articles

[Eye problems due to contact lenses; an advisory report from the Health Council of the Netherlands]

Schlingemann RO, Nieuwendaal CP.

Ned Tijdschr Geneeskd. 2002 Aug 31;146(35):1616-9. Dutch. PMID: 12233153 [PubMed - indexed for MEDLINE]Related articles

Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endothelia.

Witmer AN, Dai J, Weich HA, Vrensen GF, Schlingemann RO.

J Histochem Cytochem. 2002 Jun;50(6):767-77.PMID: 12019293 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered expression patterns of VEGF receptors in human diabetic retina and in experimental VEGF-induced retinopathy in monkey.

Witmer AN, Blaauwgeers HG, Weich HA, Alitalo K, Vrensen GF, Schlingemann RO.

Invest Ophthalmol Vis Sci. 2002 Mar;43(3):849-57.PMID: 11867607 [PubMed - indexed for MEDLINE]Related articlesFree article

VEGFR-3 in adult angiogenesis.

Witmer AN, van Blijswijk BC, Dai J, Hofman P, Partanen TA, Vrensen GF, Schlingemann RO.

J Pathol. 2001 Nov;195(4):490-7.PMID: 11745682 [PubMed - indexed for MEDLINE]Related articles

An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration.

Lahdenranta J, Pasqualini R, Schlingemann RO, Hagedorn M, Stallcup WB, Bucana CD, Sidman RL, Arap W.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10368-73.PMID: 11526242 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular localization of heparan sulfate proteoglycans in retinas of patients with diabetes mellitus and in VEGF-induced retinopathy using domain-specific antibodies.

Witmer AN, van den Born J, Vrensen GF, Schlingemann RO.

Curr Eye Res. 2001 Mar;22(3):190-7.PMID: 11462155 [PubMed - indexed for MEDLINE]Related articles

Endothelial cell hypertrophy induced by vascular endothelial growth factor in the retina: new insights into the pathogenesis of capillary nonperfusion.

Hofman P, van Blijswijk BC, Gaillard PJ, Vrensen GF, Schlingemann RO.

Arch Ophthalmol. 2001 Jun;119(6):861-6.PMID: 11405837 [PubMed - indexed for MEDLINE]Related articles

Role of VEGF-A in endothelial phenotypic shift in human diabetic retinopathy and VEGF-A-induced retinopathy in monkeys.

Hofman P, Blaauwgeers HG, Vrensen GF, Schlingemann RO.

Ophthalmic Res. 2001 May-Jun;33(3):156-62.PMID: 11340407 [PubMed - indexed for MEDLINE]Related articles