PubMed

The road from discovery to clinic: adiponectin as a biomarker of metabolic status.

Kusminski CM, Scherer PE.

Clin Pharmacol Ther. 2009 Dec;86(6):592-5.PMID: 19915603 [PubMed - in process]Related articles

Impact of Simvastatin on Adipose Tissue: Pleiotropic Effects in Vivo.

Khan T, Hamilton MP, Mundy DI, Chua SC, Scherer PE.

Endocrinology. 2009 Oct 9. [Epub ahead of print]PMID: 19819942 [PubMed - as supplied by publisher]Related articles

Chagas disease, adipose tissue and the metabolic syndrome.

Nagajyothi F, Desruisseaux MS, Weiss LM, Chua S, Albanese C, Machado FS, Esper L, Lisanti MP, Teixeira MM, Scherer PE, Tanowitz HB.

Mem Inst Oswaldo Cruz. 2009 Jul;104 Suppl 1:219-25.PMID: 19753477 [PubMed - in process]Related articlesFree article

Mechanisms of obesity and related pathologies: the macro- and microcirculation of adipose tissue.

Rutkowski JM, Davis KE, Scherer PE.

FEBS J. 2009 Oct;276(20):5738-46. Epub 2009 Sep 15. Review.PMID: 19754873 [PubMed - indexed for MEDLINE]Related articles

Perspectives on adipose tissue, chagas disease and implications for the metabolic syndrome.

Nagajyothi F, Desruisseaux MS, Jelicks LA, Machado FS, Chua S, Scherer PE, Tanowitz HB.

Interdiscip Perspect Infect Dis. 2009;2009:824324. Epub 2009 Jul 26.PMID: 19644556 [PubMed - in process]Related articlesFree article

Systemic fate of the adipocyte-derived factor adiponectin.

Halberg N, Schraw TD, Wang ZV, Kim JY, Yi J, Hamilton MP, Luby-Phelps K, Scherer PE.

Diabetes. 2009 Sep;58(9):1961-70. Epub 2009 Jul 6.PMID: 19581422 [PubMed - indexed for MEDLINE]Related articles

The transcriptional response of the islet to pregnancy in mice.

Rieck S, White P, Schug J, Fox AJ, Smirnova O, Gao N, Gupta RK, Wang ZV, Scherer PE, Keller MP, Attie AD, Kaestner KH.

Mol Endocrinol. 2009 Oct;23(10):1702-12. Epub 2009 Jul 2.PMID: 19574445 [PubMed - in process]Related articles

C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists.

Vernochet C, Peres SB, Davis KE, McDonald ME, Qiang L, Wang H, Scherer PE, Farmer SR.

Mol Cell Biol. 2009 Sep;29(17):4714-28. Epub 2009 Jun 29.PMID: 19564408 [PubMed - indexed for MEDLINE]Related articles

Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

Halberg N, Khan T, Trujillo ME, Wernstedt-Asterholm I, Attie AD, Sherwani S, Wang ZV, Landskroner-Eiger S, Dineen S, Magalang UJ, Brekken RA, Scherer PE.

Mol Cell Biol. 2009 Aug;29(16):4467-83. Epub 2009 Jun 22.PMID: 19546236 [PubMed - indexed for MEDLINE]Related articles

Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo.

Landskroner-Eiger S, Qian B, Muise ES, Nawrocki AR, Berger JP, Fine EJ, Koba W, Deng Y, Pollard JW, Scherer PE.

Clin Cancer Res. 2009 May 15;15(10):3265-76. Epub 2009 May 15.PMID: 19447867 [PubMed - indexed for MEDLINE]Related articles

Diabetes and apoptosis: lipotoxicity.

Kusminski CM, Shetty S, Orci L, Unger RH, Scherer PE.

Apoptosis. 2009 Dec;14(12):1484-95.PMID: 19421860 [PubMed - in process]Related articles

Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies.

Shetty S, Kusminski CM, Scherer PE.

Trends Pharmacol Sci. 2009 May;30(5):234-9. Epub 2009 Apr 7. Review.PMID: 19359049 [PubMed - indexed for MEDLINE]Related articles

Trypanosoma cruzi infection of cultured adipocytes results in an inflammatory phenotype.

Nagajyothi F, Desruisseaux MS, Thiruvur N, Weiss LM, Braunstein VL, Albanese C, Teixeira MM, de Almeida CJ, Lisanti MP, Scherer PE, Tanowitz HB.

Obesity (Silver Spring). 2008 Sep;16(9):1992-7.PMID: 19186325 [PubMed - indexed for MEDLINE]Related articlesFree article

PAQRs: a counteracting force to ceramides?

Holland WL, Scherer PE.

Mol Pharmacol. 2009 Apr;75(4):740-3. Epub 2009 Jan 21. Review.PMID: 19158359 [PubMed - indexed for MEDLINE]Related articles

Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.

Khan T, Muise ES, Iyengar P, Wang ZV, Chandalia M, Abate N, Zhang BB, Bonaldo P, Chua S, Scherer PE.

Mol Cell Biol. 2009 Mar;29(6):1575-91. Epub 2008 Dec 29.PMID: 19114551 [PubMed - indexed for MEDLINE]Related articlesFree article

DsbA-L is a versatile player in adiponectin secretion.

Wang ZV, Scherer PE.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18077-8. Epub 2008 Nov 19. No abstract available. PMID: 19020096 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipocyte metabolism and obesity.

Attie AD, Scherer PE.

J Lipid Res. 2009 Apr;50 Suppl:S395-9. Epub 2008 Nov 17. Review.PMID: 19017614 [PubMed - indexed for MEDLINE]Related articles

Adiponectin: no longer the lone soul in the fight against insulin resistance?

Davis KE, Scherer PE.

Biochem J. 2008 Dec 1;416(2):e7-9.PMID: 18990088 [PubMed - indexed for MEDLINE]Related articles

The adipocyte as an endocrine cell.

Halberg N, Wernstedt-Asterholm I, Scherer PE.

Endocrinol Metab Clin North Am. 2008 Sep;37(3):753-68, x-xi. Review.PMID: 18775362 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin levels and genotype: a potential regulator of life span in humans.

Atzmon G, Pollin TI, Crandall J, Tanner K, Schechter CB, Scherer PE, Rincon M, Siegel G, Katz M, Lipton RB, Shuldiner AR, Barzilai N.

J Gerontol A Biol Sci Med Sci. 2008 May;63(5):447-53.PMID: 18511746 [PubMed - indexed for MEDLINE]Related articles

PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation.

Wang ZV, Mu J, Schraw TD, Gautron L, Elmquist JK, Zhang BB, Brownlee M, Scherer PE.

Diabetes. 2008 Aug;57(8):2137-48. Epub 2008 May 9.PMID: 18469203 [PubMed - indexed for MEDLINE]Related articlesFree article

Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.

Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A.

Diabetes. 2008 Aug;57(8):1999-2011. Epub 2008 May 5.PMID: 18458147 [PubMed - indexed for MEDLINE]Related articlesFree article

The adipokine SAA3 is induced by interleukin-1beta in mouse adipocytes.

Sommer G, Weise S, Kralisch S, Scherer PE, Lössner U, Blüher M, Stumvoll M, Fasshauer M.

J Cell Biochem. 2008 Aug 15;104(6):2241-7.PMID: 18452164 [PubMed - indexed for MEDLINE]Related articles

Analysis of the association of proteins with membranes.

Okamoto T, Schwab RB, Scherer PE, Lisanti MP.

Curr Protoc Cell Biol. 2001 May;Chapter 5:Unit 5.4.PMID: 18228372 [PubMed - indexed for MEDLINE]Related articles

Plasma adiponectin complexes have distinct biochemical characteristics.

Schraw T, Wang ZV, Halberg N, Hawkins M, Scherer PE.

Endocrinology. 2008 May;149(5):2270-82. Epub 2008 Jan 17.PMID: 18202126 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse Models of Lipodystrophy Key reagents for the understanding of the metabolic syndrome.

Asterholm IW, Halberg N, Scherer PE.

Drug Discov Today Dis Models. 2007;4(1):17-24.PMID: 18193096 [PubMed]Related articlesFree article

Adipocytokine and ghrelin levels in relation to cardiovascular disease risk factors in women at midlife: longitudinal associations.

Wildman RP, Mancuso P, Wang C, Kim M, Scherer PE, Sowers MR.

Int J Obes (Lond). 2008 May;32(5):740-8. Epub 2008 Jan 8.PMID: 18180784 [PubMed - indexed for MEDLINE]Related articles

Adiponectin, cardiovascular function, and hypertension.

Wang ZV, Scherer PE.

Hypertension. 2008 Jan;51(1):8-14. Epub 2007 Nov 12. Review. No abstract available. PMID: 17998473 [PubMed - indexed for MEDLINE]Related articlesFree article

Analytical validation and biological evaluation of a high molecular-weight adiponectin ELISA.

Sinha MK, Songer T, Xiao Q, Sloan JH, Wang J, Ji S, Alborn WE, Davis RA, Swarbrick MM, Stanhope KL, Wolfe BM, Havel PJ, Schraw T, Konrad RJ, Scherer PE, Mistry JS.

Clin Chem. 2007 Dec;53(12):2144-51. Epub 2007 Oct 19.PMID: 17951289 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity-associated improvements in metabolic profile through expansion of adipose tissue.

Kim JY, van de Wall E, Laplante M, Azzara A, Trujillo ME, Hofmann SM, Schraw T, Durand JL, Li H, Li G, Jelicks LA, Mehler MF, Hui DY, Deshaies Y, Shulman GI, Schwartz GJ, Scherer PE.

J Clin Invest. 2007 Sep;117(9):2621-37.PMID: 17717599 [PubMed - indexed for MEDLINE]Related articlesFree article

Within-individual stability of obesity-related biomarkers among women.

Kaplan RC, Ho GY, Xue X, Rajpathak S, Cushman M, Rohan TE, Strickler HD, Scherer PE, Anastos K.

Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1291-3.PMID: 17548700 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic resistin induces hepatic insulin resistance.

Muse ED, Lam TK, Scherer PE, Rossetti L.

J Clin Invest. 2007 Jun;117(6):1670-8. Epub 2007 May 24.PMID: 17525801 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects.

Basu R, Pajvani UB, Rizza RA, Scherer PE.

Diabetes. 2007 Aug;56(8):2174-7. Epub 2007 May 18.PMID: 17513700 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice.

Lin HV, Kim JY, Pocai A, Rossetti L, Shapiro L, Scherer PE, Accili D.

Diabetes. 2007 Aug;56(8):1969-76. Epub 2007 May 2.PMID: 17475934 [PubMed - indexed for MEDLINE]Related articlesFree article

Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection.

Ashton AW, Mukherjee S, Nagajyothi FN, Huang H, Braunstein VL, Desruisseaux MS, Factor SM, Lopez L, Berman JW, Wittner M, Scherer PE, Capra V, Coffman TM, Serhan CN, Gotlinger K, Wu KK, Weiss LM, Tanowitz HB.

J Exp Med. 2007 Apr 16;204(4):929-40. Epub 2007 Apr 9.PMID: 17420269 [PubMed - indexed for MEDLINE]Related articlesFree article

Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention.

Wang ZV, Schraw TD, Kim JY, Khan T, Rajala MW, Follenzi A, Scherer PE.

Mol Cell Biol. 2007 May;27(10):3716-31. Epub 2007 Mar 12.PMID: 17353260 [PubMed - indexed for MEDLINE]Related articlesFree article

Progressive loss of beta-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes.

Cnop M, Vidal J, Hull RL, Utzschneider KM, Carr DB, Schraw T, Scherer PE, Boyko EJ, Fujimoto WY, Kahn SE.

Diabetes Care. 2007 Mar;30(3):677-82.PMID: 17327340 [PubMed - indexed for MEDLINE]Related articlesFree article

Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies.

Semple RK, Halberg NH, Burling K, Soos MA, Schraw T, Luan J, Cochran EK, Dunger DB, Wareham NJ, Scherer PE, Gorden P, O'Rahilly S.

Diabetes. 2007 Jun;56(6):1712-7. Epub 2007 Feb 26.PMID: 17325257 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2.

Kim JJ, Kido Y, Scherer PE, White MF, Accili D.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1694-701. Epub 2007 Feb 13.PMID: 17299086 [PubMed - indexed for MEDLINE]Related articlesFree article

Visceral fat adipokine secretion is associated with systemic inflammation in obese humans.

Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S.

Diabetes. 2007 Apr;56(4):1010-3. Epub 2007 Feb 7.PMID: 17287468 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin complexes in human cerebrospinal fluid: distinct complex distribution from serum.

Kusminski CM, McTernan PG, Schraw T, Kos K, O'Hare JP, Ahima R, Kumar S, Scherer PE.

Diabetologia. 2007 Mar;50(3):634-42. Epub 2007 Jan 23.PMID: 17242917 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor gamma agonists inhibit adipocyte expression of alpha1-acid glycoprotein.

Castriota G, Thompson GM, Lin Y, Scherer PE, Moller DE, Berger JP.

Cell Biol Int. 2007 Jun;31(6):586-91. Epub 2006 Dec 15.PMID: 17240171 [PubMed - indexed for MEDLINE]Related articles

Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle.

Li W, Tonelli J, Kishore P, Owen R, Goodman E, Scherer PE, Hawkins M.

Am J Physiol Endocrinol Metab. 2007 May;292(5):E1301-7. Epub 2007 Jan 9. Erratum in: Am J Physiol Endocrinol Metab. 2009 Feb;296(2):E402. PMID: 17213476 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain adipocytokine action and metabolic regulation.

Ahima RS, Qi Y, Singhal NS, Jackson MB, Scherer PE.

Diabetes. 2006 Dec;55 Suppl 2:S145-54. Review.PMID: 17130638 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipocyte, adipose tissue, and infectious disease.

Desruisseaux MS, Nagajyothi, Trujillo ME, Tanowitz HB, Scherer PE.

Infect Immun. 2007 Mar;75(3):1066-78. Epub 2006 Nov 21. Review. No abstract available. PMID: 17118983 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of resistin improves glucose homeostasis in leptin deficiency.

Qi Y, Nie Z, Lee YS, Singhal NS, Scherer PE, Lazar MA, Ahima RS.

Diabetes. 2006 Nov;55(11):3083-90.PMID: 17065346 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue-derived factors: impact on health and disease.

Trujillo ME, Scherer PE.

Endocr Rev. 2006 Dec;27(7):762-78. Epub 2006 Oct 20. Review.PMID: 17056740 [PubMed - indexed for MEDLINE]Related articlesFree article

Keystone meeting summary: 'Adipogenesis, obesity, and inflammation' and 'Diabetes mellitus and the control of cellular energy metabolism, ' January 21-26, 2006, Vancouver, Canada.

Corvera S, Burkart A, Kim JY, Christianson J, Wang Z, Scherer PE.

Genes Dev. 2006 Aug 15;20(16):2193-201.PMID: 16912272 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of transcription factor NFAT in glucose and insulin homeostasis.

Yang TT, Suk HY, Yang X, Olabisi O, Yu RY, Durand J, Jelicks LA, Kim JY, Scherer PE, Wang Y, Feng Y, Rossetti L, Graef IA, Crabtree GR, Chow CW.

Mol Cell Biol. 2006 Oct;26(20):7372-87. Epub 2006 Aug 14.PMID: 16908540 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin.

Zhao Z, Deocharan B, Scherer PE, Ozelius LJ, Putterman C.

J Immunol. 2006 Jun 15;176(12):7704-14.PMID: 16751418 [PubMed - indexed for MEDLINE]Related articlesFree article