PubMed

Protective vascular and myocardial effects of adiponectin.

Goldstein BJ, Scalia RG, Ma XL.

Nat Clin Pract Cardiovasc Med. 2009 Jan;6(1):27-35. Epub 2008 Nov 25. Review.PMID: 19029992 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial S100A1 modulates vascular function via nitric oxide.

Pleger ST, Harris DM, Shan C, Vinge LE, Chuprun JK, Berzins B, Pleger W, Druckman C, Völkers M, Heierhorst J, Øie E, Remppis A, Katus HA, Scalia R, Eckhart AD, Koch WJ, Most P.

Circ Res. 2008 Apr 11;102(7):786-94. Epub 2008 Feb 21.PMID: 18292599 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin protects against angiotensin II or tumor necrosis factor alpha-induced endothelial cell monolayer hyperpermeability: role of cAMP/PKA signaling.

Xu SQ, Mahadev K, Wu X, Fuchsel L, Donnelly S, Scalia RG, Goldstein BJ.

Arterioscler Thromb Vasc Biol. 2008 May;28(5):899-905. Epub 2008 Feb 21.PMID: 18292388 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of endothelial function by in vivo microscopy.

Scalia R.

Methods Mol Med. 2007;139:225-35.PMID: 18287675 [PubMed - indexed for MEDLINE]Related articles

Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function.

Elrod JW, Calvert JW, Morrison J, Doeller JE, Kraus DW, Tao L, Jiao X, Scalia R, Kiss L, Szabo C, Kimura H, Chow CW, Lefer DJ.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15560-5. Epub 2007 Sep 18.PMID: 17878306 [PubMed - indexed for MEDLINE]Related articlesFree article

Comment on: Hattori et al. (2007) Globular adiponectin activates nuclear factor-kappaB and activating protein-1 and enhances angiotensin II-induced proliferation in cardiac fibroblasts: Diabetes 56:804-808.

Goldstein BJ, Scalia R, Ma XL, Mahadev K, Wu X, Ouedraogo R.

Diabetes. 2007 Jul;56(7):e7-8; author reply e9-10. No abstract available. PMID: 17596407 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo.

Ouedraogo R, Gong Y, Berzins B, Wu X, Mahadev K, Hough K, Chan L, Goldstein BJ, Scalia R.

J Clin Invest. 2007 Jun;117(6):1718-26.PMID: 17549259 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycemia is a major determinant of albumin permeability in diabetic microcirculation: the role of mu-calpain.

Scalia R, Gong Y, Berzins B, Zhao LJ, Sharma K.

Diabetes. 2007 Jul;56(7):1842-9. Epub 2007 Apr 19.PMID: 17446533 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipokines and vascular disease in diabetes.

Goldstein BJ, Scalia R.

Curr Diab Rep. 2007 Feb;7(1):25-33. Review.PMID: 17254515 [PubMed - indexed for MEDLINE]Related articles

Herpes simplex virus in the saliva of peripheral Bell's palsy patients.

Lazarini PR, Vianna MF, Alcantara MP, Scalia RA, Caiaffa Filho HH.

Braz J Otorhinolaryngol. 2006 Jan-Feb;72(1):7-11.PMID: 16917546 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway.

Ouedraogo R, Wu X, Xu SQ, Fuchsel L, Motoshima H, Mahadev K, Hough K, Scalia R, Goldstein BJ.

Diabetes. 2006 Jun;55(6):1840-6.PMID: 16731851 [PubMed - indexed for MEDLINE]Related articlesFree article

Statins and the response to myocardial injury.

Scalia R.

Am J Cardiovasc Drugs. 2005;5(3):163-70. Review.PMID: 15901204 [PubMed - indexed for MEDLINE]Related articles

The calcium-dependent protease calpain causes endothelial dysfunction in type 2 diabetes.

Stalker TJ, Gong Y, Scalia R.

Diabetes. 2005 Apr;54(4):1132-40.PMID: 15793253 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection.

Wolfrum S, Dendorfer A, Rikitake Y, Stalker TJ, Gong Y, Scalia R, Dominiak P, Liao JK.

Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1842-7. Epub 2004 Aug 19.PMID: 15319269 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin: A novel adipokine linking adipocytes and vascular function.

Goldstein BJ, Scalia R.

J Clin Endocrinol Metab. 2004 Jun;89(6):2563-8. Review.PMID: 15181024 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel role for calpains in the endothelial dysfunction of hyperglycemia.

Stalker TJ, Skvarka CB, Scalia R.

FASEB J. 2003 Aug;17(11):1511-3. Epub 2003 Jun 3.PMID: 12824289 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes.

Wu X, Motoshima H, Mahadev K, Stalker TJ, Scalia R, Goldstein BJ.

Diabetes. 2003 Jun;52(6):1355-63.PMID: 12765944 [PubMed - indexed for MEDLINE]Related articlesFree article

Microcirculation as a target for the anti-inflammatory properties of statins.

Scalia R, Stalker TJ.

Microcirculation. 2002 Dec;9(6):431-42. Review.PMID: 12483541 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of amelioration of glucose-induced endothelial dysfunction following inhibition of protein kinase C in vivo.

Booth G, Stalker TJ, Lefer AM, Scalia R.

Diabetes. 2002 May;51(5):1556-64.PMID: 11978656 [PubMed - indexed for MEDLINE]Related articlesFree article

HMG-CoA reductase inhibition protects the diabetic myocardium from ischemia-reperfusion injury.

Lefer DJ, Scalia R, Jones SP, Sharp BR, Hoffmeyer MR, Farvid AR, Gibson MF, Lefer AM.

FASEB J. 2001 Jun;15(8):1454-6. No abstract available. PMID: 11387255 [PubMed - indexed for MEDLINE]Related articlesFree article

Simvastatin exerts both anti-inflammatory and cardioprotective effects in apolipoprotein E-deficient mice.

Scalia R, Gooszen ME, Jones SP, Hoffmeyer M, Rimmer DM 3rd, Trocha SD, Huang PL, Smith MB, Lefer AM, Lefer DJ.

Circulation. 2001 May 29;103(21):2598-603.PMID: 11382730 [PubMed - indexed for MEDLINE]Related articlesFree article

A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: the role of mevalonic acid.

Stalker TJ, Lefer AM, Scalia R.

Br J Pharmacol. 2001 Jun;133(3):406-12.PMID: 11375257 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated ambient glucose induces acute inflammatory events in the microvasculature: effects of insulin.

Booth G, Stalker TJ, Lefer AM, Scalia R.

Am J Physiol Endocrinol Metab. 2001 Jun;280(6):E848-56.PMID: 11350766 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of nitric oxide in the regulation of acute and chronic inflammation.

Laroux FS, Lefer DJ, Kawachi S, Scalia R, Cockrell AS, Gray L, Van der Heyde H, Hoffman JM, Grisham MB.

Antioxid Redox Signal. 2000 Fall;2(3):391-6. Review.PMID: 11229352 [PubMed - indexed for MEDLINE]Related articles

Cardioprotective effects of citrulline in ischemia/reperfusion injury via a non-nitric oxide-mediated mechanism.

Ikeda Y, Young LH, Scalia R, Lefer AM.

Methods Find Exp Clin Pharmacol. 2000 Sep;22(7):563-71.PMID: 11196344 [PubMed - indexed for MEDLINE]Related articles

Vascular effects of HMG CoA-reductase inhibitors (statins) unrelated to cholesterol lowering: new concepts for cardiovascular disease.

Lefer AM, Scalia R, Lefer DJ.

Cardiovasc Res. 2001 Feb 1;49(2):281-7. Review. No abstract available. PMID: 11164838 [PubMed - indexed for MEDLINE]Related articlesFree article

PR-39, a proline/arginine-rich antimicrobial peptide, exerts cardioprotective effects in myocardial ischemia-reperfusion.

Ikeda Y, Young LH, Scalia R, Ross CR, Lefer AM.

Cardiovasc Res. 2001 Jan;49(1):69-77.PMID: 11121797 [PubMed - indexed for MEDLINE]Related articlesFree article

PR-39, a potent neutrophil inhibitor, attenuates myocardial ischemia-reperfusion injury in mice.

Hoffmeyer MR, Scalia R, Ross CR, Jones SP, Lefer DJ.

Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2824-8.PMID: 11087237 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial ischemia/reperfusion injury in NADPH oxidase-deficient mice.

Hoffmeyer MR, Jones SP, Ross CR, Sharp B, Grisham MB, Laroux FS, Stalker TJ, Scalia R, Lefer DJ.

Circ Res. 2000 Oct 27;87(9):812-7.PMID: 11055986 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide inhibits leukocyte-endothelium interaction in the microcirculation during acute endothelial dysfunction.

Scalia R, Coyle KM, Levine BJ, Booth G, Lefer AM.

FASEB J. 2000 Nov;14(14):2357-64.PMID: 11053258 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide exerts cardioprotective effects in myocardial ischemia-reperfusion.

Young LH, Ikeda Y, Scalia R, Lefer AM.

Am J Physiol Heart Circ Physiol. 2000 Oct;279(4):H1453-9.PMID: 11009429 [PubMed - indexed for MEDLINE]Related articlesFree article

Wortmannin, a potent antineutrophil agent, exerts cardioprotective effects in myocardial ischemia/reperfusion.

Young LH, Ikeda Y, Scalia R, Lefer AM.

J Pharmacol Exp Ther. 2000 Oct;295(1):37-43.PMID: 10991958 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapid restoration of normal endothelial functions in genetically hyperlipidemic mice by a synthetic mediator of reverse lipid transport.

Williams KJ, Scalia R, Mazany KD, Rodrigueza WV, Lefer AM.

Arterioscler Thromb Vasc Biol. 2000 Apr;20(4):1033-9.PMID: 10764669 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel lysophosphatidic acid analog, LXR-1035, inhibits leukocyte-endothelium interaction via inhibition of cell adhesion molecules.

Scalia R, Pruefer D, Lefer AM.

J Leukoc Biol. 2000 Jan;67(1):26-33.PMID: 10647994 [PubMed - indexed for MEDLINE]Related articlesFree article

Homocysteine provokes leukocyte-endothelium interaction by downregulation of nitric oxide.

Pruefer D, Scalia R, Lefer AM.

Gen Pharmacol. 1999 Dec;33(6):487-98.PMID: 10647774 [PubMed - indexed for MEDLINE]Related articles

Simvastatin inhibits leukocyte-endothelial cell interactions and protects against inflammatory processes in normocholesterolemic rats.

Pruefer D, Scalia R, Lefer AM.

Arterioscler Thromb Vasc Biol. 1999 Dec;19(12):2894-900.PMID: 10591666 [PubMed - indexed for MEDLINE]Related articlesFree article

Simvastatin preserves the ischemic-reperfused myocardium in normocholesterolemic rat hearts.

Lefer AM, Campbell B, Shin YK, Scalia R, Hayward R, Lefer DJ.

Circulation. 1999 Jul 13;100(2):178-84.PMID: 10402448 [PubMed - indexed for MEDLINE]Related articlesFree article

Leukocyte-endothelial cell interactions in nitric oxide synthase-deficient mice.

Lefer DJ, Jones SP, Girod WG, Baines A, Grisham MB, Cockrell AS, Huang PL, Scalia R.

Am J Physiol. 1999 Jun;276(6 Pt 2):H1943-50.PMID: 10362674 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factor attenuates leukocyte-endothelium interaction during acute endothelial dysfunction: essential role of endothelium-derived nitric oxide.

Scalia R, Booth G, Lefer DJ.

FASEB J. 1999 Jun;13(9):1039-46.PMID: 10336886 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant soluble P-selectin glycoprotein ligand-1 protects against myocardial ischemic reperfusion injury in cats.

Hayward R, Campbell B, Shin YK, Scalia R, Lefer AM.

Cardiovasc Res. 1999 Jan;41(1):65-76.PMID: 10325954 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role of P-selectin in the initiation of the inflammatory response induced by hemorrhage and reinfusion.

Scalia R, Armstead VE, Minchenko AG, Lefer AM.

J Exp Med. 1999 Mar 15;189(6):931-8.PMID: 10075976 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of recombinant soluble P-selectin glycoprotein ligand-1 on leukocyte-endothelium interaction in vivo. Role in rat traumatic shock.

Scalia R, Hayward R, Armstead VE, Minchenko AG, Lefer AM.

Circ Res. 1999 Jan 8-22;84(1):93-102.PMID: 9915778 [PubMed - indexed for MEDLINE]Related articlesFree article

Beneficial effects of N,N,N-trimethylsphingosine following ischemia and reperfusion in the isolated perfused rat heart.

Campbell B, Shin YK, Scalia R, Lefer AM.

Cardiovasc Res. 1998 Aug;39(2):393-400.PMID: 9798524 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of LEX032, a novel recombinant serine protease inhibitor, on N(G)-nitro-L-arginine methyl ester induced leukocyte-endothelial cell interactions.

Bains AS, Scalia R, Lefer AM.

Eur J Pharmacol. 1998 Aug 28;356(1):67-72.PMID: 9761425 [PubMed - indexed for MEDLINE]Related articles

Synergism between platelets and neutrophils in provoking cardiac dysfunction after ischemia and reperfusion: role of selectins.

Lefer AM, Campbell B, Scalia R, Lefer DJ.

Circulation. 1998 Sep 29;98(13):1322-8.PMID: 9751682 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo regulation of PECAM-1 activity during acute endothelial dysfunction in the rat mesenteric microvasculature.

Scalia R, Lefer AM.

J Leukoc Biol. 1998 Aug;64(2):163-9.PMID: 9715254 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular mechanisms of heparinase III protection in rat traumatic shock.

Hayward R, Scalia R, Hopper B, Appel JZ 3rd, Lefer AM.

Am J Physiol. 1998 Jul;275(1 Pt 2):H23-30.PMID: 9688892 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of cardioprotection by peroxynitrite in myocardial ischemia and reperfusion injury.

Nossuli TO, Hayward R, Jensen D, Scalia R, Lefer AM.

Am J Physiol. 1998 Aug;275(2 Pt 2):H509-19.PMID: 9683439 [PubMed - indexed for MEDLINE]Related articlesFree article

Leukocyte-endothelium interaction during the early stages of hypercholesterolemia in the rabbit: role of P-selectin, ICAM-1, and VCAM-1.

Scalia R, Appel JZ 3rd, Lefer AM.

Arterioscler Thromb Vasc Biol. 1998 Jul;18(7):1093-100.PMID: 9672069 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardioprotective effect of interleukin-10 in murine myocardial ischemia-reperfusion.

Hayward R, Nossuli TO, Scalia R, Lefer AM.

Eur J Pharmacol. 1997 Sep 10;334(2-3):157-63.PMID: 9369344 [PubMed - indexed for MEDLINE]Related articles