PubMed

Validation of eight genetic risk factors in East Asian populations replicated the association of BRAP with coronary artery disease.

Hinohara K, Ohtani H, Nakajima T, Sasaoka T, Sawabe M, Lee BS, Ban J, Park JE, Izumi T, Kimura A.

J Hum Genet. 2009 Nov;54(11):642-6. Epub 2009 Aug 28.PMID: 19713974 [PubMed - in process]Related articles

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity.

Tao H, Suzuki M, Kiyonari H, Abe T, Sasaoka T, Ueno N.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14426-31. Epub 2009 Aug 11.PMID: 19706528 [PubMed - indexed for MEDLINE]Related articles

Validation of the association between AGTRL1 polymorphism and coronary artery disease in the Japanese and Korean populations.

Hinohara K, Nakajima T, Sasaoka T, Sawabe M, Lee BS, Ban JM, Park JE, Izumi T, Kimura A.

J Hum Genet. 2009 Sep;54(9):554-6. Epub 2009 Aug 14.PMID: 19680269 [PubMed - in process]Related articles

Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease.

Hinohara K, Nakajima T, Yasunami M, Houda S, Sasaoka T, Yamamoto K, Lee BS, Shibata H, Tanaka-Takahashi Y, Takahashi M, Arimura T, Sato A, Naruse T, Ban J, Inoko H, Yamada Y, Sawabe M, Park JE, Izumi T, Kimura A.

Hum Genet. 2009 Oct;126(4):539-47. Epub 2009 Jun 10.PMID: 19513752 [PubMed - indexed for MEDLINE]Related articles

Role of orexin in the regulation of glucose homeostasis.

Tsuneki H, Wada T, Sasaoka T.

Acta Physiol (Oxf). 2009 May 28. [Epub ahead of print]PMID: 19489767 [PubMed - as supplied by publisher]Related articles

The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain morphology in schizophrenia.

Takahashi T, Suzuki M, Tsunoda M, Maeno N, Kawasaki Y, Zhou SY, Hagino H, Niu L, Tsuneki H, Kobayashi S, Sasaoka T, Seto H, Kurachi M, Ozaki N.

Psychiatry Res. 2009 May 15;172(2):128-35. Epub 2009 Mar 21.PMID: 19304459 [PubMed - indexed for MEDLINE]Related articles

Replication studies for the association of PSMA6 polymorphism with coronary artery disease in East Asian populations.

Hinohara K, Nakajima T, Sasaoka T, Sawabe M, Lee BS, Ban J, Park JE, Izumi T, Kimura A.

J Hum Genet. 2009 Apr;54(4):248-51. Epub 2009 Mar 13.PMID: 19282875 [PubMed - in process]Related articles

Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3T3-L1 adipocytes.

Wada T, Ohshima S, Fujisawa E, Koya D, Tsuneki H, Sasaoka T.

Endocrinology. 2009 Apr;150(4):1662-9. Epub 2008 Dec 18.PMID: 19095745 [PubMed - indexed for MEDLINE]Related articles

Impact of lipid phosphatases SHIP2 and PTEN on the time- and Akt-isoform-specific amelioration of TNF-alpha-induced insulin resistance in 3T3-L1 adipocytes.

Ikubo M, Wada T, Fukui K, Ishiki M, Ishihara H, Asano T, Tsuneki H, Sasaoka T.

Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E157-64. Epub 2008 Nov 11.PMID: 19001549 [PubMed - indexed for MEDLINE]Related articles

Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts.

Sasaoka T, Egi Y, Tawa M, Yamamoto A, Ohkita M, Takaoka M, Maruyama T, Akira T, Matsumura Y.

J Cardiovasc Pharmacol. 2008 Aug;52(2):176-83.PMID: 18670361 [PubMed - indexed for MEDLINE]Related articles

Caveolin-3 deficiency decreases the gene expression level of osteopontin in mdx mouse skeletal muscle.

Hagiwara Y, Fujita M, Imamura M, Noguchi S, Sasaoka T.

Acta Myol. 2006 Oct;25(2):53-61.PMID: 18593005 [PubMed - indexed for MEDLINE]Related articles

Characteristics of signalling properties mediated by long-acting insulin analogue glargine and detemir in target cells of insulin.

Wada T, Azegami M, Sugiyama M, Tsuneki H, Sasaoka T.

Diabetes Res Clin Pract. 2008 Sep;81(3):269-77. Epub 2008 Jun 27.PMID: 18585815 [PubMed - indexed for MEDLINE]Related articles

The association of genotypic combination of the DRD3 and BDNF polymorphisms on the adhesio interthalamica and medial temporal lobe structures.

Takahashi T, Suzuki M, Tsunoda M, Kawamura Y, Takahashi N, Maeno N, Kawasaki Y, Zhou SY, Hagino H, Niu L, Tsuneki H, Kobayashi S, Sasaoka T, Seto H, Kurachi M, Ozaki N.

Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1236-42. Epub 2008 Mar 25.PMID: 18472202 [PubMed - indexed for MEDLINE]Related articles

Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells.

Kawasaki K, Watabe T, Sase H, Hirashima M, Koide H, Morishita Y, Yuki K, Sasaoka T, Suda T, Katsuki M, Miyazono K, Miyazawa K.

J Cell Biol. 2008 Apr 7;181(1):131-41.PMID: 18391074 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between the brain-derived neurotrophic factor Val66Met polymorphism and brain morphology in a Japanese sample of schizophrenia and healthy comparisons.

Takahashi T, Suzuki M, Tsunoda M, Kawamura Y, Takahashi N, Tsuneki H, Kawasaki Y, Zhou SY, Kobayashi S, Sasaoka T, Seto H, Kurachi M, Ozaki N.

Neurosci Lett. 2008 Apr 11;435(1):34-9. Epub 2008 Feb 9.PMID: 18325670 [PubMed - indexed for MEDLINE]Related articles

Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations.

Hinohara K, Nakajima T, Takahashi M, Hohda S, Sasaoka T, Nakahara K, Chida K, Sawabe M, Arimura T, Sato A, Lee BS, Ban JM, Yasunami M, Park JE, Izumi T, Kimura A.

J Hum Genet. 2008;53(4):357-9. Epub 2008 Feb 9.PMID: 18264662 [PubMed - indexed for MEDLINE]Related articles

Age-related insulin resistance in hypothalamus and peripheral tissues of orexin knockout mice.

Tsuneki H, Murata S, Anzawa Y, Soeda Y, Tokai E, Wada T, Kimura I, Yanagisawa M, Sakurai T, Sasaoka T.

Diabetologia. 2008 Apr;51(4):657-67. Epub 2008 Feb 7.PMID: 18256806 [PubMed - indexed for MEDLINE]Related articles

Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice.

Kagawa S, Soeda Y, Ishihara H, Oya T, Sasahara M, Yaguchi S, Oshita R, Wada T, Tsuneki H, Sasaoka T.

Endocrinology. 2008 Feb;149(2):642-50. Epub 2007 Nov 26.PMID: 18039790 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of BMP10 with Tcap may modulate the course of hypertensive cardiac hypertrophy.

Nakano N, Hori H, Abe M, Shibata H, Arimura T, Sasaoka T, Sawabe M, Chida K, Arai T, Nakahara K, Kubo T, Sugimoto K, Katsuya T, Ogihara T, Doi Y, Izumi T, Kimura A.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3396-403. Epub 2007 Oct 5.PMID: 17921333 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis of poison-frog alkaloids 233A, 235U, and 251AA and their inhibitory effects on neuronal nicotinic acetylcholine receptors.

Toyooka N, Kobayashi S, Zhou D, Tsuneki H, Wada T, Sakai H, Nemoto H, Sasaoka T, Garraffo HM, Spande TF, Daly JW.

Bioorg Med Chem Lett. 2007 Nov 1;17(21):5872-5. Epub 2007 Aug 26.PMID: 17827002 [PubMed - indexed for MEDLINE]Related articles

Platelet-derived growth factor (PDGF)-BB inhibits AMPA receptor-mediated synaptic transmission via PDGF receptor-beta in murine nucleus tractus solitarius.

Ohi Y, Ishii Y, Haji A, Noguchi S, Sasaoka T, Fujimori T, Nabeshima Y, Sasahara M, Hattori Y.

Brain Res. 2007 Jul 23;1159:77-85. Epub 2007 May 31.PMID: 17573050 [PubMed - indexed for MEDLINE]Related articles

Lack of association between LTA and LGALS2 polymorphisms and myocardial infarction in Japanese and Korean populations.

Kimura A, Takahashi M, Choi BY, Bae SW, Hohta S, Sasaoka T, Nakahara KI, Chida K, Sawabe M, Yasunami M, Naruse T, Izumi T, Park JE.

Tissue Antigens. 2007 Mar;69(3):265-9.PMID: 17493152 [PubMed - indexed for MEDLINE]Related articles

Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells.

Tsuneki H, Sekizaki N, Suzuki T, Kobayashi S, Wada T, Okamoto T, Kimura I, Sasaoka T.

Eur J Pharmacol. 2007 Jul 2;566(1-3):1-10. Epub 2007 Mar 19.PMID: 17434478 [PubMed - indexed for MEDLINE]Related articles

Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy.

Arimura T, Hayashi T, Matsumoto Y, Shibata H, Hiroi S, Nakamura T, Inagaki N, Hinohara K, Takahashi M, Manatsu SI, Sasaoka T, Izumi T, Bonne G, Schwartz K, Kimura A.

Biochem Biophys Res Commun. 2007 May 25;357(1):162-7. Epub 2007 Mar 30.PMID: 17416352 [PubMed - indexed for MEDLINE]Related articles

Telmisartan reduced blood pressure and HOMA-IR with increasing plasma leptin level in hypertensive and type 2 diabetic patients.

Usui I, Fujisaka S, Yamazaki K, Takano A, Murakami S, Yamazaki Y, Urakaze M, Hachiya H, Takata M, Senda S, Iwata M, Satoh A, Sasaoka T, Ak ND, Temaru R, Kobayashi M.

Diabetes Res Clin Pract. 2007 Aug;77(2):210-4. Epub 2007 Jan 19.PMID: 17240472 [PubMed - indexed for MEDLINE]Related articles

Cys669-Cys713 disulfide bridge formation is a key to dystroglycan cleavage and subunit association.

Watanabe N, Sasaoka T, Noguchi S, Nishino I, Tanaka T.

Genes Cells. 2007 Jan;12(1):75-88.PMID: 17212656 [PubMed - indexed for MEDLINE]Related articles

Novel G423S mutation of human alpha7 nicotinic receptor promotes agonist-induced desensitization by a protein kinase C-dependent mechanism.

Tsuneki H, Kobayashi S, Takagi K, Kagawa S, Tsunoda M, Murata M, Matsuoka T, Wada T, Kurachi M, Kimura I, Sasaoka T.

Mol Pharmacol. 2007 Mar;71(3):777-86. Epub 2006 Nov 28.PMID: 17132684 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic nicotine exposure enhances insulin-induced mitogenic signaling via up-regulation of alpha7 nicotinic receptors in isolated rat aortic smooth muscle cells.

Wada T, Naito M, Kenmochi H, Tsuneki H, Sasaoka T.

Endocrinology. 2007 Feb;148(2):790-9. Epub 2006 Oct 26.PMID: 17068140 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid phosphatases as a possible therapeutic target in cases of type 2 diabetes and obesity.

Sasaoka T, Wada T, Tsuneki H.

Pharmacol Ther. 2006 Dec;112(3):799-809. Epub 2006 Jul 13. Review.PMID: 16842857 [PubMed - indexed for MEDLINE]Related articles

Mouse brains deficient in neuronal PDGF receptor-beta develop normally but are vulnerable to injury.

Ishii Y, Oya T, Zheng L, Gao Z, Kawaguchi M, Sabit H, Matsushima T, Tokunaga A, Ishizawa S, Hori E, Nabeshima Y, Sasaoka T, Fujimori T, Mori H, Sasahara M.

J Neurochem. 2006 Jul;98(2):588-600.PMID: 16805849 [PubMed - indexed for MEDLINE]Related articles

Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.

Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S.

Development. 2006 May;133(9):1735-44. Epub 2006 Mar 29. Erratum in: Development. 2006 May;133(9):1855. PMID: 16571631 [PubMed - indexed for MEDLINE]Related articlesFree article

Hydroponic cultivation offers a practical means of producing selenium-enriched garlic.

Tsuneyoshi T, Yoshida J, Sasaoka T.

J Nutr. 2006 Mar;136(3 Suppl):870S-872S.PMID: 16484583 [PubMed - indexed for MEDLINE]Related articlesFree article

Tetrahydro-beta-carboline derivatives in aged garlic extract show antioxidant properties.

Ichikawa M, Yoshida J, Ide N, Sasaoka T, Yamaguchi H, Ono K.

J Nutr. 2006 Mar;136(3 Suppl):726S-731S.PMID: 16484551 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered subcellular distribution of estrogen receptor alpha is implicated in estradiol-induced dual regulation of insulin signaling in 3T3-L1 adipocytes.

Nagira K, Sasaoka T, Wada T, Fukui K, Ikubo M, Hori S, Tsuneki H, Saito S, Kobayashi M.

Endocrinology. 2006 Feb;147(2):1020-8. Epub 2005 Nov 3.PMID: 16269459 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1alpha inhibits insulin signaling with phosphorylating insulin receptor substrate-1 on serine residues in 3T3-L1 adipocytes.

He J, Usui I, Ishizuka K, Kanatani Y, Hiratani K, Iwata M, Bukhari A, Haruta T, Sasaoka T, Kobayashi M.

Mol Endocrinol. 2006 Jan;20(1):114-24. Epub 2005 Sep 8.PMID: 16150868 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5'-phosphatase 2) on insulin signaling and glucose metabolism in mice.

Fukui K, Wada T, Kagawa S, Nagira K, Ikubo M, Ishihara H, Kobayashi M, Sasaoka T.

Diabetes. 2005 Jul;54(7):1958-67.PMID: 15983195 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular and cell biology of the sarcoglycan complex.

Ozawa E, Mizuno Y, Hagiwara Y, Sasaoka T, Yoshida M.

Muscle Nerve. 2005 Nov;32(5):563-76. Review.PMID: 15937871 [PubMed - indexed for MEDLINE]Related articles

Antiangiogenic activity of beta-eudesmol in vitro and in vivo.

Tsuneki H, Ma EL, Kobayashi S, Sekizaki N, Maekawa K, Sasaoka T, Wang MW, Kimura I.

Eur J Pharmacol. 2005 Apr 11;512(2-3):105-15.PMID: 15840394 [PubMed - indexed for MEDLINE]Related articles

Marine alkaloids (-)-pictamine and (-)-lepadin B block neuronal nicotinic acetylcholine receptors.

Tsuneki H, You Y, Toyooka N, Sasaoka T, Nemoto H, Dani JA, Kimura I.

Biol Pharm Bull. 2005 Apr;28(4):611-4.PMID: 15802796 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of SRC homology 2-containing inositol 5'-phosphatase 2 gene polymorphisms detected in a Japanese population on insulin signaling.

Kagawa S, Sasaoka T, Yaguchi S, Ishihara H, Tsuneki H, Murakami S, Fukui K, Wada T, Kobayashi S, Kimura I, Kobayashi M.

J Clin Endocrinol Metab. 2005 May;90(5):2911-9. Epub 2005 Feb 1.PMID: 15687335 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of endogenous SHIP2 ameliorates insulin resistance caused by chronic insulin treatment in 3T3-L1 adipocytes.

Sasaoka T, Fukui K, Wada T, Murakami S, Kawahara J, Ishihara H, Funaki M, Asano T, Kobayashi M.

Diabetologia. 2005 Feb;48(2):336-44. Epub 2005 Jan 15.PMID: 15654601 [PubMed - indexed for MEDLINE]Related articles

Deletion of the PDGFR-beta gene affects key fibroblast functions important for wound healing.

Gao Z, Sasaoka T, Fujimori T, Oya T, Ishii Y, Sabit H, Kawaguchi M, Kurotaki Y, Naito M, Wada T, Ishizawa S, Kobayashi M, Nabeshima Y, Sasahara M.

J Biol Chem. 2005 Mar 11;280(10):9375-89. Epub 2004 Dec 6.PMID: 15590688 [PubMed - indexed for MEDLINE]Related articlesFree article

Nicotinic enhancement of proliferation in bovine and porcine cerebral microvascular endothelial cells.

Tsuneki H, Ito K, Sekizaki N, Ma EL, You Y, Kawakami J, Adachi I, Sasaoka T, Kimura I.

Biol Pharm Bull. 2004 Dec;27(12):1951-6.PMID: 15577211 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans.

Tsuneki H, Ishizuka M, Terasawa M, Wu JB, Sasaoka T, Kimura I.

BMC Pharmacol. 2004 Aug 26;4:18.PMID: 15331020 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-synemin localizes to regions of high stress in human skeletal myofibers.

Mizuno Y, Guyon JR, Watkins SC, Mizushima K, Sasaoka T, Imamura M, Kunkel LM, Okamoto K.

Muscle Nerve. 2004 Sep;30(3):337-46.PMID: 15318345 [PubMed - indexed for MEDLINE]Related articles

Alkaloids indolizidine 235B', quinolizidine 1-epi-207I, and the tricyclic 205B are potent and selective noncompetitive inhibitors of nicotinic acetylcholine receptors.

Tsuneki H, You Y, Toyooka N, Kagawa S, Kobayashi S, Sasaoka T, Nemoto H, Kimura I, Dani JA.

Mol Pharmacol. 2004 Oct;66(4):1061-9. Epub 2004 Jul 16.PMID: 15258256 [PubMed - indexed for MEDLINE]Related articlesFree article

Nelfinavir-induced insulin resistance is associated with impaired plasma membrane recruitment of the PI 3-kinase effectors Akt/PKB and PKC-zeta.

Ben-Romano R, Rudich A, Tirosh A, Potashnik R, Sasaoka T, Riesenberg K, Schlaeffer F, Bashan N.

Diabetologia. 2004 Jun;47(6):1107-17. Epub 2004 May 28.PMID: 15168016 [PubMed - indexed for MEDLINE]Related articles

Impact of Src homology 2-containing inositol 5'-phosphatase 2 on the regulation of insulin signaling leading to protein synthesis in 3T3-L1 adipocytes cultured with excess amino acids.

Murakami S, Sasaoka T, Wada T, Fukui K, Nagira K, Ishihara H, Usui I, Kobayashi M.

Endocrinology. 2004 Jul;145(7):3215-23. Epub 2004 Mar 24.PMID: 15044364 [PubMed - indexed for MEDLINE]Related articlesFree article

[Ectopic ACTH-producing bronchial carcinoid tumor]

Iwata M, Yamamoto Y, Fujita T, Hayashi R, Igarashi Y, Satou A, Sasaoka T, Maruyama M, Kobayashi M, Matsui K.

Nippon Naika Gakkai Zasshi. 2004 Feb 10;93(2):370-2. Japanese. No abstract available. PMID: 15007946 [PubMed - indexed for MEDLINE]Related articles

[Recombinant antibodies: basics and application to medicine]

Tanaka T, Sasaoka T.

Seikagaku. 2003 Dec;75(12):1551-5. Review. Japanese. No abstract available. PMID: 14748151 [PubMed - indexed for MEDLINE]Related articles