PubMed

The novel radical scavenger IAC is effective in preventing and protecting against post-ischemic brain damage in Mongolian gerbils.

Canistro D, Affatato AA, Soleti A, Mollace V, Muscoli C, Sculco F, Sacco I, Visalli V, Bonamassa B, Martano M, Iannone M, Sapone A, Paolini M.

J Neurol Sci. 2009 Nov 27. [Epub ahead of print]PMID: 19945716 [PubMed - as supplied by publisher]Related articles

Differential Mucosal IL-17 Expression in Two Gliadin-Induced Disorders: Gluten Sensitivity and the Autoimmune Enteropathy Celiac Disease.

Sapone A, Lammers KM, Mazzarella G, Mikhailenko I, Cartenì M, Casolaro V, Fasano A.

Int Arch Allergy Immunol. 2009 Nov 24;152(1):75-80. [Epub ahead of print]PMID: 19940509 [PubMed - as supplied by publisher]Related articles

Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms.

Visser J, Rozing J, Sapone A, Lammers K, Fasano A.

Ann N Y Acad Sci. 2009 May;1165:195-205. Review.PMID: 19538307 [PubMed - indexed for MEDLINE]Related articles

Intestinal permeability in patients with chronic liver diseases: It's relationship with the aetiology and the entity of liver damage.

Cariello R, Federico A, Sapone A, Tuccillo C, Scialdone VR, Tiso A, Miranda A, Portincasa P, Carbonara V, Palasciano G, Martorelli L, Esposito P, Cartenì M, Del Vecchio Blanco C, Loguercio C.

Dig Liver Dis. 2009 Jun 5. [Epub ahead of print]PMID: 19502117 [PubMed - as supplied by publisher]Related articles

Hidden paradoxes in generic drug substitution affecting pharmacotherapy.

Sapone A, Canistro D, Bonamassa B, Biagi GL, Paolini M.

J Biomed Biotechnol. 2009;2009:801984. Epub 2009 May 21. No abstract available. PMID: 19478953 [PubMed - indexed for MEDLINE]Related articlesFree article

Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice.

Canistro D, Bonamassa B, Pozzetti L, Sapone A, Abdel-Rahman SZ, Biagi GL, Paolini M.

Food Chem Toxicol. 2009 Feb;47(2):454-61. Epub 2008 Dec 10.PMID: 19101601 [PubMed - indexed for MEDLINE]Related articles

High-dose vitamin A.

Sapone A, Bonamassa B, Canistro D, Pozzetti L, Paolini M.

Lancet. 2007 Sep 1;370(9589):740. No abstract available. PMID: 17765521 [PubMed - indexed for MEDLINE]Related articles

Perturbation of murine liver cyp-superfamily of isoforms by different combinations of pesticide mixtures.

Canistro D, Pozzetti L, Sapone A, Broccoli M, Affatato AA, Stradiotti A, Longo V, Menichini P, Barale R, Paolini M.

Food Chem Toxicol. 2008 Jan;46(1):34-42. Epub 2007 Jun 28.PMID: 17686559 [PubMed - indexed for MEDLINE]Related articles

Perturbation of rat hepatic metabolising enzymes by folic acid supplementation.

Canistro D, Pozzetti L, Sapone A, Broccoli M, Bonamassa B, Longo V, Lubrano V, Barillari J, Biagi GL, Paolini M.

Mutat Res. 2008 Jan 1;637(1-2):16-22. Epub 2007 Jun 28.PMID: 17681554 [PubMed - indexed for MEDLINE]Related articles

Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of brassicaceae, differently affect metabolizing enzymes in rats.

Barillari J, Iori R, Broccoli M, Pozzetti L, Canistro D, Sapone A, Bonamassa B, Biagi GL, Paolini M.

J Agric Food Chem. 2007 Jul 11;55(14):5505-11. Epub 2007 Jun 19.PMID: 17579433 [PubMed - indexed for MEDLINE]Related articles

Cruciferous vegetables and lung cancer.

Sapone A, Affatato A, Canistro D, Pozzetti L, Broccoli M, Barillari J, Iori R, Paolini M.

Mutat Res. 2007 May-Jun;635(2-3):146-8. Epub 2006 Dec 15. No abstract available. PMID: 17174594 [PubMed - indexed for MEDLINE]Related articles

Perturbation of cytochrome P450, generation of oxidative stress and induction of DNA damage in Cyprinus carpio exposed in situ to potable surface water.

Sapone A, Gustavino B, Monfrinotti M, Canistro D, Broccoli M, Pozzetti L, Affatato A, Valgimigli L, Forti GC, Pedulli GF, Biagi GL, Abdel-Rahman SZ, Paolini M.

Mutat Res. 2007 Jan 10;626(1-2):143-54. Epub 2006 Dec 1.PMID: 17141554 [PubMed - indexed for MEDLINE]Related articles

Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives.

Sapone A, de Magistris L, Pietzak M, Clemente MG, Tripathi A, Cucca F, Lampis R, Kryszak D, Cartenì M, Generoso M, Iafusco D, Prisco F, Laghi F, Riegler G, Carratu R, Counts D, Fasano A.

Diabetes. 2006 May;55(5):1443-9.PMID: 16644703 [PubMed - indexed for MEDLINE]Related articlesFree article

Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines.

Drago S, El Asmar R, Di Pierro M, Grazia Clemente M, Tripathi A, Sapone A, Thakar M, Iacono G, Carroccio A, D'Agate C, Not T, Zampini L, Catassi C, Fasano A.

Scand J Gastroenterol. 2006 Apr;41(4):408-19.PMID: 16635908 [PubMed - indexed for MEDLINE]Related articles

Intestinal permeability and diabetes mellitus type 2.

Secondulfo M, de Magistris L, Sapone A, Di Monda G, Esposito P, Carratù R.

Minerva Gastroenterol Dietol. 1999 Sep;45(3):187-92. English, Italian. PMID: 16498329 [PubMed]Related articles

Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac disease.

Thomas KE, Sapone A, Fasano A, Vogel SN.

J Immunol. 2006 Feb 15;176(4):2512-21.PMID: 16456012 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver.

Perocco P, Bronzetti G, Canistro D, Valgimigli L, Sapone A, Affatato A, Pedulli GF, Pozzetti L, Broccoli M, Iori R, Barillari J, Sblendorio V, Legator MS, Paolini M, Abdel-Rahman SZ.

Mutat Res. 2006 Mar 20;595(1-2):125-36.PMID: 16442570 [PubMed - indexed for MEDLINE]Related articles

Green tea and its isolated constituents in cancer prevention.

Sapone A, Canistro D, Broccoli M, Pozzetti L, Affatato A, Vangelisti S, Biagi GL, Sblendorio V, Paolini M.

Mutat Res. 2005 Oct 15;578(1-2):434-5. Epub 2005 Mar 19. No abstract available. PMID: 16202797 [PubMed - indexed for MEDLINE]Related articles

Quantitative evaluation of oxidative stress status on peripheral blood in beta-thalassaemic patients by means of electron paramagnetic resonance spectroscopy.

Filosa A, Valgimigli L, Pedulli GF, Sapone A, Maggio A, Renda D, Scazzone C, Malizia R, Pitrolo L, Lo Pinto C, Borsellino Z, Cuccia L, Capra M, Canistro D, Broccoli M, Soleti A, Paolini M.

Br J Haematol. 2005 Oct;131(1):135-40.PMID: 16173974 [PubMed - indexed for MEDLINE]Related articles

Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats.

Watts T, Berti I, Sapone A, Gerarduzzi T, Not T, Zielke R, Fasano A.

Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2916-21. Epub 2005 Feb 14.PMID: 15710870 [PubMed - indexed for MEDLINE]Related articlesFree article

CYP superfamily perturbation by diflubenzuron or acephate in different tissues of CD1 mice.

Sapone A, Pozzetti L, Canistro D, Broccoli M, Bronzetti G, Potenza G, Affatato A, Biagi GL, Cantelli-Forti G, Paolini M.

Food Chem Toxicol. 2005 Jan;43(1):173-83.PMID: 15582210 [PubMed - indexed for MEDLINE]Related articles

Parkinson's disease, pesticides and individual vulnerability.

Paolini M, Sapone A, Gonzalez FJ.

Trends Pharmacol Sci. 2004 Mar;25(3):124-9. Review. No abstract available. PMID: 15019266 [PubMed - indexed for MEDLINE]Related articles

Ultrastructural mucosal alterations and increased intestinal permeability in non-celiac, type I diabetic patients.

Secondulfo M, Iafusco D, Carratù R, deMagistris L, Sapone A, Generoso M, Mezzogiomo A, Sasso FC, Cartenì M, De Rosa R, Prisco F, Esposito V.

Dig Liver Dis. 2004 Jan;36(1):35-45.PMID: 14971814 [PubMed - indexed for MEDLINE]Related articles

Antioxidant vitamins for prevention of cardiovascular disease.

Paolini M, Sapone A, Canistro D, Chieco P, Valgimigli L.

Lancet. 2003 Sep 13;362(9387):920; author reply 921. No abstract available. PMID: 13678992 [PubMed - indexed for MEDLINE]Related articles

Infection with Giardia and intestinal permeability in humans.

De Magistris L, Secondulfo M, Sapone A, Carratù R, Iafusco D, Prisco F, Generoso M, Cartenì M, Mezzogiorno A, Esposito V.

Gastroenterology. 2003 Jul;125(1):277-9; author reply 279. No abstract available. PMID: 12870499 [PubMed - indexed for MEDLINE]Related articles

The clinical role of cytochrome p450 genotypes in Helicobacter pylori management.

Sapone A, Vaira D, Trespidi S, Perna F, Gatta L, Tampieri A, Ricci C, Cantelli-Forti G, Miglioli M, Biagi GL, Paolini M.

Am J Gastroenterol. 2003 May;98(5):1010-5.PMID: 12809821 [PubMed - indexed for MEDLINE]Related articles

Avoidance of bioflavonoid supplements during pregnancy: a pathway to infant leukemia?

Paolini M, Sapone A, Valgimigli L.

Mutat Res. 2003 Jun 19;527(1-2):99-101. No abstract available. PMID: 12787918 [PubMed - indexed for MEDLINE]Related articles

Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice.

Sapone A, Affatato A, Canistro D, Broccoli M, Trespidi S, Pozzetti L, Biagi GL, Cantelli-Forti G, Paolini M.

Mutat Res. 2003 Jun 19;527(1-2):67-80.PMID: 12787915 [PubMed - indexed for MEDLINE]Related articles

Beta-carotene: a cancer chemopreventive agent or a co-carcinogen?

Paolini M, Abdel-Rahman SZ, Sapone A, Pedulli GF, Perocco P, Cantelli-Forti G, Legator MS.

Mutat Res. 2003 Jun;543(3):195-200.PMID: 12787812 [PubMed - indexed for MEDLINE]Related articles

Diet and risk of cancer.

Paolini M, Sapone A, Canistro D, Antonelli MA, Chieco P.

Lancet. 2003 Jan 18;361(9353):257-8. No abstract available. PMID: 12547566 [PubMed - indexed for MEDLINE]Related articles

Dietary effect on blood pressure.

Paolini M, Sapone A, Canistro D, Chieco P, Bauer C.

Lancet. 2002 Nov 30;360(9347):1786. No abstract available. PMID: 12480457 [PubMed - indexed for MEDLINE]Related articles

In vitro induction of benzo(a)pyrene cell-transforming activity by the glucosinolate gluconasturtiin found in cruciferous vegetables.

Perocco P, Iori R, Barillari J, Broccoli M, Sapone A, Affatato A, Paolini M.

Cancer Lett. 2002 Oct 8;184(1):65-71.PMID: 12104049 [PubMed - indexed for MEDLINE]Related articles

The pressing need for combined genotype-phenotype analysis in clinical practice.

Sapone A, Paolini M, Biagi GL, Cantelli-Forti G, Gonzalez FJ.

Trends Pharmacol Sci. 2002 Jun;23(6):260-1. No abstract available. PMID: 12084629 [PubMed - indexed for MEDLINE]Related articles

Identification of novel polymorphisms in the 5' flanking region of CYP1A2, characterization of interethnic variability, and investigation of their functional significance.

Aitchison KJ, Gonzalez FJ, Quattrochi LC, Sapone A, Zhao JH, Zaher H, Elizondo G, Bryant C, Munro J, Collier DA, Makoffa AI, Kerwin RW.

Pharmacogenetics. 2000 Nov;10(8):695-704.PMID: 11186132 [PubMed - indexed for MEDLINE]Related articles

The human peroxisome proliferator-activated receptor alpha gene: identification and functional characterization of two natural allelic variants.

Sapone A, Peters JM, Sakai S, Tomita S, Papiha SS, Dai R, Friedman FK, Gonzalez FJ.

Pharmacogenetics. 2000 Jun;10(4):321-33.PMID: 10862523 [PubMed - indexed for MEDLINE]Related articles

CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity.

Sata F, Sapone A, Elizondo G, Stocker P, Miller VP, Zheng W, Raunio H, Crespi CL, Gonzalez FJ.

Clin Pharmacol Ther. 2000 Jan;67(1):48-56.PMID: 10668853 [PubMed - indexed for MEDLINE]Related articles

Nomenclature for human DPYD alleles.

McLeod HL, Collie-Duguid ES, Vreken P, Johnson MR, Wei X, Sapone A, Diasio RB, Fernandez-Salguero P, van Kuilenberg AB, van Gennip AH, Gonzalez FJ.

Pharmacogenetics. 1998 Dec;8(6):455-9.PMID: 9918128 [PubMed - indexed for MEDLINE]Related articles

Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects.

Ridge SA, Sludden J, Brown O, Robertson L, Wei X, Sapone A, Fernandez-Salguero PM, Gonzalez FJ, Vreken P, van Kuilenburg AB, van Gennip AH, McLeod HL.

Br J Clin Pharmacol. 1998 Aug;46(2):151-6.PMID: 9723824 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the human dihydropyrimidine dehydrogenase gene.

Wei X, Elizondo G, Sapone A, McLeod HL, Raunio H, Fernandez-Salguero P, Gonzalez FJ.

Genomics. 1998 Aug 1;51(3):391-400.PMID: 9721209 [PubMed - indexed for MEDLINE]Related articles

Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer.

Ridge SA, Sludden J, Wei X, Sapone A, Brown O, Hardy S, Canney P, Fernandez-Salguero P, Gonzalez FJ, Cassidy J, McLeod HL.

Br J Cancer. 1998;77(3):497-500.PMID: 9472650 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of licorice and glycyrrhizin on murine liver CYP-dependent monooxygenases.

Paolini M, Pozzetti L, Sapone A, Cantelli-Forti G.

Life Sci. 1998;62(6):571-82.PMID: 9464470 [PubMed - indexed for MEDLINE]Related articles

Development of basal and induced testosterone hydroxylase activity in the chicken embryo in ovo.

Paolini M, Pozzetti L, Sapone A, Biagi GL, Cantelli-Forti G.

Br J Pharmacol. 1997 Sep;122(2):344-50.PMID: 9313945 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular non-genetic biomarkers of effect related to acephate cocarcinogenesis: sex- and tissue-dependent induction or suppression of murine CYPs.

Paolini M, Pozzetti L, Sapone A, Mesirca R, Perocco P, Mazzullo M, Cantelli-Forti G.

Cancer Lett. 1997 Jul 15;117(1):7-15.PMID: 9233825 [PubMed - indexed for MEDLINE]Related articles

Lack of correlation between phenotype and genotype for the polymorphically expressed dihydropyrimidine dehydrogenase in a family of Pakistani origin.

Fernandez-Salguero PM, Sapone A, Wei X, Holt JR, Jones S, Idle JR, Gonzalez FJ.

Pharmacogenetics. 1997 Apr;7(2):161-3.PMID: 9170156 [PubMed - indexed for MEDLINE]Related articles

Biomarkers of effect in evaluating dithianon cocarcinogenesis: selective induction and suppression of murine CYP3A isoform.

Paolini M, Mesirca R, Pozzetti L, Sapone A, Cantelli-Forti G.

Cancer Lett. 1997 Feb 26;113(1-2):221-8.PMID: 9065825 [PubMed - indexed for MEDLINE]Related articles

Biomarkers of effect in evaluating metalaxyl cocarcinogenesis. Selective induction of murine CYP 3A isoform.

Paolini M, Mesirca R, Pozzetti L, Sapone A, Cantelli-Forti G.

Mutat Res. 1996 Dec 12;361(2-3):157-64.PMID: 8980701 [PubMed - indexed for MEDLINE]Related articles

Molecular non-genetic biomarkers related to Fenarimol cocarcinogenesis: organ- and sex-specific CYP induction in rat.

Paolini M, Mesirca R, Pozzetti L, Sapone A, Cantelli-Forti G.

Cancer Lett. 1996 Mar 29;101(2):171-8.PMID: 8620466 [PubMed - indexed for MEDLINE]Related articles

[Experimental osteoporosis caused by estrogen deficiency in rats. Role of a lactose, L-arginine and L-lysine combination in the prevention and therapy]

Fini M, Giardino R, Mongiorgi R, Cantelli Forti G, Gnudi S, Nicoli Aldini N, Valdrè C, Piotti D, Giavaresi G, Orienti L, Rocca M, Sapone A, Rossetti A.

Minerva Med. 1996 Mar;87(3):81-8. Italian. PMID: 8668292 [PubMed - indexed for MEDLINE]Related articles

Testosterone hydroxylase in evaluating induction and suppression of murine CYP isoenzymes by fenarimol.

Paolini M, Pozzetti L, Mesirca R, Sapone A, Cantelli-Forti G.

Arch Toxicol. 1996;70(7):451-6.PMID: 8740540 [PubMed - indexed for MEDLINE]Related articles

[Role of lactose, arginine and lysine combination in fracture healing (an experimental study)]

Fini M, Giardino R, Nicoli Aldini N, Martini L, Rocca M, Bertoni F, Capelli S, Cantelli Forti G, Sapone A, Rossetti A, Morrone G, Giavaresi G.

Ann Ital Chir. 1996 Jan-Feb;67(1):77-82; discussion 82-3. Italian. PMID: 8712622 [PubMed - indexed for MEDLINE]Related articles