PubMed

Valproic acid at therapeutic plasma levels may increase 5-azacytidine efficacy in higher risk myelodysplastic syndromes.

Voso MT, Santini V, Finelli C, Musto P, Pogliani E, Angelucci E, Fioritoni G, Alimena G, Maurillo L, Cortelezzi A, Buccisano F, Gobbi M, Borin L, Di Tucci A, Zini G, Petti MC, Martinelli G, Fabiani E, Fazi P, Vignetti M, Piciocchi A, Liso V, Amadori S, Leone G.

Clin Cancer Res. 2009 Aug 1;15(15):5002-7. Epub 2009 Jul 28.PMID: 19638460 [PubMed - in process]Related articles

Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury.

McKee AC, Cantu RC, Nowinski CJ, Hedley-Whyte ET, Gavett BE, Budson AE, Santini VE, Lee HS, Kubilus CA, Stern RA.

J Neuropathol Exp Neurol. 2009 Jul;68(7):709-35. Review.PMID: 19535999 [PubMed - indexed for MEDLINE]Related articles

Is survival enough for myelodysplastic syndromes?

Santini V.

Leuk Res. 2009 Aug;33(8):1017-8. Epub 2009 Mar 5. No abstract available. PMID: 19268362 [PubMed - indexed for MEDLINE]Related articles

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study.

Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Santini V, Finelli C, Giagounidis A, Schoch R, Gattermann N, Sanz G, List A, Gore SD, Seymour JF, Bennett JM, Byrd J, Backstrom J, Zimmerman L, McKenzie D, Beach C, Silverman LR; International Vidaza High-Risk MDS Survival Study Group.

Lancet Oncol. 2009 Mar;10(3):223-32. Epub 2009 Feb 21.PMID: 19230772 [PubMed - indexed for MEDLINE]Related articles

Do parents know about the adverse effects of passive smoking and the relationship with respiratory illness on their children?

Jiménez-González C, Santini V, Figueroa Cosme WI, Parilla Idel C.

Bol Asoc Med P R. 2008 Apr-Jun;100(2):39-46.PMID: 19227729 [PubMed - indexed for MEDLINE]Related articles

Treatment options in myelodysplastic syndromes: a new frontier.

Santini V, Gozzini A, Bosi A.

J Chemother. 2008 Jun;20(3):291-6. Review.PMID: 18606581 [PubMed - indexed for MEDLINE]Related articles

The addition of liposomal doxorubicin to bortezomib, thalidomide and dexamethasone significantly improves clinical outcome of advanced multiple myeloma.

Ciolli S, Leoni F, Casini C, Breschi C, Santini V, Bosi A.

Br J Haematol. 2008 Jun;141(6):814-9. Epub 2008 Apr 10.PMID: 18410447 [PubMed - indexed for MEDLINE]Related articles

Clock drawing performance in cognitively normal elderly.

Hubbard EJ, Santini V, Blankevoort CG, Volkers KM, Barrup MS, Byerly L, Chaisson C, Jefferson AL, Kaplan E, Green RC, Stern RA.

Arch Clin Neuropsychol. 2008 May;23(3):295-327. Epub 2008 Feb 19.PMID: 18243644 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of JAK2V617F allele burden on phenotype in essential thrombocythemia.

Antonioli E, Guglielmelli P, Poli G, Bogani C, Pancrazzi A, Longo G, Ponziani V, Tozzi L, Pieri L, Santini V, Bosi A, Vannucchi AM; Myeloproliferative Disorders Research Consortium (MPD-RC).

Haematologica. 2008 Jan;93(1):41-8.PMID: 18166784 [PubMed - indexed for MEDLINE]Related articlesFree article

Polycythemia vera following autologous transplantation for AML: insights on the kinetics of JAK2V617F clonal dominance.

Antonioli E, Guglielmelli P, Poli G, Santini V, Bosi A, Vannucchi AM.

Blood. 2007 Dec 15;110(13):4620-1. No abstract available. PMID: 18056850 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells.

Barbetti V, Gozzini A, Rovida E, Morandi A, Spinelli E, Fossati G, Mascagni P, Lübbert M, Dello Sbarba P, Santini V.

Oncogene. 2008 Mar 13;27(12):1767-78. Epub 2007 Sep 24.PMID: 17891169 [PubMed - indexed for MEDLINE]Related articles

Histone deacetylase inhibitors: molecular and biological activity as a premise to clinical application.

Santini V, Gozzini A, Ferrari G.

Curr Drug Metab. 2007 May;8(4):383-93. Review.PMID: 17504226 [PubMed - indexed for MEDLINE]Related articles

QTc and autonomic neuropathy in diabetes: effects of acute hyperglycaemia and n-3 PUFA.

Santini V, Ciampittiello G, Gigli F, Bracaglia D, Baroni A, Cicconetti E, Verri C, Gambardella S, Frontoni S.

Nutr Metab Cardiovasc Dis. 2007 Dec;17(10):712-8. Epub 2007 Feb 26.PMID: 17324562 [PubMed - indexed for MEDLINE]Related articles

A selective activity of DNMTi decitabine on AML1ETO positive cells?

Santini V.

Leuk Res. 2007 Jun;31(6):741-2. Epub 2007 Jan 22. Review. No abstract available. PMID: 17240447 [PubMed - indexed for MEDLINE]Related articles

Comparative proteomic analysis of chronic myelogenous leukemia cells: inside the mechanism of imatinib resistance.

Ferrari G, Pastorelli R, Buchi F, Spinelli E, Gozzini A, Bosi A, Santini V.

J Proteome Res. 2007 Jan;6(1):367-75.PMID: 17203980 [PubMed - indexed for MEDLINE]Related articles

The c-Jun-N-terminal-Kinase inhibitor SP600125 enhances the butyrate derivative D1-induced apoptosis via caspase 8 activation in Kasumi 1 t(8;21) acute myeloid leukaemia cells.

Rovida E, Gozzini A, Barbetti V, Giuntoli S, Santini V, Dello Sbarba P.

Br J Haematol. 2006 Dec;135(5):653-9. Epub 2006 Oct 19.PMID: 17054427 [PubMed - indexed for MEDLINE]Related articles

Hemolymphangiomatosis of the spleen: imaging features.

Santoro L, Santini V, Lollo SD, Valeri A, Colagrande S.

J Comput Assist Tomogr. 2005 Nov-Dec;29(6):831-3.PMID: 16272860 [PubMed - indexed for MEDLINE]Related articles

Butyrates and decitabine cooperate to induce histone acetylation and granulocytic maturation of t(8;21) acute myeloid leukemia blasts.

Gozzini A, Santini V.

Ann Hematol. 2005 Dec;84 Suppl 1:54-60.PMID: 16228241 [PubMed - indexed for MEDLINE]Related articles

No preferential sensitivity of t(8;21) acute myeloid leukemias to cytosine arabinoside in vitro: is intensity of therapy or high dose Ara-C crucial for response?

Visani G, Isidori A, Grafone T, Tosi P, Santini V, Malagola M, Martinelli G, Piccaluga PP, Gaziev D, Ottaviani E, Sparaventi G, Tura S.

Leuk Lymphoma. 2004 Jul;45(7):1361-4.PMID: 15359633 [PubMed - indexed for MEDLINE]Related articles

Evaluation of BCRP and MDR-1 co-expression by quantitative molecular assessment in AML patients.

Galimberti S, Guerrini F, Palumbo GA, Consoli U, Fazzi R, Morabito F, Santini V, Petrini M.

Leuk Res. 2004 Apr;28(4):367-72.PMID: 15109536 [PubMed - indexed for MEDLINE]Related articles

Butyrates, as a single drug, induce histone acetylation and granulocytic maturation: possible selectivity on core binding factor-acute myeloid leukemia blasts.

Gozzini A, Rovida E, Dello Sbarba P, Galimberti S, Santini V.

Cancer Res. 2003 Dec 15;63(24):8955-61. Erratum in: Cancer Res. 2004 May 15;;64(14):3725. Galimbert S [corrected to Galimberti S]. PMID: 14695213 [PubMed - indexed for MEDLINE]Related articlesFree article

Dependence of leukemic cell autofluorescence patterns on the degree of differentiation.

Monici M, Agati G, Fusi F, Pratesi R, Paglierani M, Santini V, Bernabei PA.

Photochem Photobiol Sci. 2003 Oct;2(10):981-7.PMID: 14606752 [PubMed - indexed for MEDLINE]Related articles

FLT3 mutations do not influence MDR-1 gene expression in acute myeloid leukemia.

Galimberti S, Rossi A, Palumbo GA, Morabito F, Guerrini F, Vincelli I, Fazzi R, Santini V, Petrini M.

Anticancer Res. 2003 Jul-Aug;23(4):3419-26.PMID: 12926083 [PubMed - indexed for MEDLINE]Related articles

In vitro antileukemic effect of a new anthracycline analogue, MEN 11079.

Biscardi M, Caporale R, Pagliai G, Leoni F, Bernabei P, Santini V, Ciolli S, Grossi A.

Leuk Res. 2003 Dec;27(12):1125-34.PMID: 12921951 [PubMed - indexed for MEDLINE]Related articles

The carboxy-terminal region of the granulocyte colony-stimulating factor receptor transduces a phagocytic signal.

Santini V, Scappini B, Indik ZK, Gozzini A, Ferrini PR, Schreiber AD.

Blood. 2003 Jun 1;101(11):4615-22. Epub 2003 Feb 13.PMID: 12586631 [PubMed - indexed for MEDLINE]Related articlesFree article

Lyn kinase is activated following thrombopoietin stimulation of the megakaryocytic cell line B1647.

Santini V, Scappini B, Grossi A, Gozzini A, Bonsi L, Pagliai G, Rossi Ferrini P, Bagnara GP.

Haematologica. 2002 Dec;87(12):1242-7.PMID: 12495897 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined therapy with amifostine plus erythropoietin for the treatment of myelodysplastic syndromes.

Grossi A, Musto P, Santini V, Balestri F, Fabbri A, Falcone A, Sanpaolo G.

Haematologica. 2002 Mar;87(3):322-3.PMID: 11869946 [PubMed - indexed for MEDLINE]Related articlesFree article

Homoharringtonine: history, current research, and future direction.

Kantarjian HM, Talpaz M, Santini V, Murgo A, Cheson B, O'Brien SM.

Cancer. 2001 Sep 15;92(6):1591-605. Review.PMID: 11745238 [PubMed - indexed for MEDLINE]Related articlesFree article

Searching for the magic bullet against cancer: the butyrate saga.

Santini V, Gozzini A, Scappini B, Grossi A, Rossi Ferrini P.

Leuk Lymphoma. 2001 Jul;42(3):275-89. Review.PMID: 11699392 [PubMed - indexed for MEDLINE]Related articles

Amifostine: chemotherapeutic and radiotherapeutic protective effects.

Santini V.

Expert Opin Pharmacother. 2001 Mar;2(3):479-89. Review.PMID: 11336600 [PubMed - indexed for MEDLINE]Related articles

Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

Santini V, Kantarjian HM, Issa JP.

Ann Intern Med. 2001 Apr 3;134(7):573-86. Review.PMID: 11281740 [PubMed - indexed for MEDLINE]Related articlesFree article

Fludarabine, cytarabine and topotecan (FLAT) as induction therapy for acute myeloid leukemia in the elderly: a preliminary report.

Leoni F, Ciolli S, Nozzoli C, Santini V, Fanci R, Rossi Ferrini P.

Haematologica. 2001 Jan;86(1):104. No abstract available. PMID: 11146581 [PubMed - indexed for MEDLINE]Related articlesFree article

Amifostine in the treatment of low-risk myelodysplastic syndromes.

Grossi A, Fabbri A, Santini V, Leoni F, Nozzoli C, Longo G, Pagliai G, Ciolli S, Rossi Ferrini P.

Haematologica. 2000 Apr;85(4):367-71.PMID: 10756361 [PubMed - indexed for MEDLINE]Related articlesFree article

Sequential cis-platinum and fludarabine with or without arabinosyl cytosine in patients failing prior fludarabine therapy for chronic lymphocytic leukemia: a phase II study.

Giles FJ, O'Brien SM, Santini V, Gandhi V, Plunkett W, Seymour JF, Robertson LE, Kantarjian HM, Keating MJ.

Leuk Lymphoma. 1999 Dec;36(1-2):57-65.PMID: 10613450 [PubMed - indexed for MEDLINE]Related articles

The potential of amifostine: from cytoprotectant to therapeutic agent.

Santini V, Giles FJ.

Haematologica. 1999 Nov;84(11):1035-42. Review.PMID: 10553165 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunohistochemistry applied to the study of bone marrow Gaucher's cells: a case report.

Alterini R, Rigacci L, Stefanacci S, Innocenti F, Santini V, Carrai V, Rossi Ferrini P.

Eur J Histochem. 1999;43(3):235-9.PMID: 10563256 [PubMed - indexed for MEDLINE]Related articles

Induction of apoptosis by monosaccharide butyrate stable derivatives in chronic lymphocytic leukemia cells.

Santini V, Gozzini A, Scappini B, Caporale R, Zoccolante A, Rigacci L, Gelardi E, Grossi A, Alterini R, Ferrini PR.

Haematologica. 1999 Oct;84(10):897-904.PMID: 10509037 [PubMed - indexed for MEDLINE]Related articlesFree article

Activity of vinorelbine on B-chronic lymphocytic leukemia cells in vitro.

Bernabei PA, Landini I, Bartolozzi B, Banchelli I, Degli Innocenti o Nocentini A, Santini V, Ematologia UO.

Adv Exp Med Biol. 1999;457:473-6.PMID: 10500824 [PubMed - indexed for MEDLINE]Related articles

Natural fluorescence imaging of leukemic cells for studying uptake and retention of anthracyclines.

Monici M, Fusi F, Mazzinghi P, Degli Innocenti o Nocentini A, Landini I, Banchelli I, Bartolozzi B, Santini V, Bernabei PA.

Adv Exp Med Biol. 1999;457:89-94. No abstract available. PMID: 10500784 [PubMed - indexed for MEDLINE]Related articles

Maturation and apoptosis of primary human acute myeloblastic leukemia cells are determined by TNF-alpha exclusively through CD120A stimulation.

Santini V, Gozzini A, Scappini B, Rossi Ferrini P.

Haematologica. 1999 Apr;84(4):291-7.PMID: 10190941 [PubMed - indexed for MEDLINE]Related articlesFree article

Pure red cell aplasia in autoimmune polyglandular syndrome with T lymphocytosis.

Grossi A, Nozzoli C, Gheri R, Santini V, Marrani C, Zoccolante A, Ferrini PR.

Haematologica. 1998 Nov;83(11):1043-5.PMID: 9864928 [PubMed - indexed for MEDLINE]Related articlesFree article

Regioselective synthesis and biological profiling of butyric and phenylalkylcarboxylic esters derivated from D-mannose and xylitol: influence of alkyl chain length on acute toxicity.

Pouillart P, Douillet O, Scappini B, Gozzini A, Santini V, Grossi A, Pagliai G, Strippoli P, Rigacci L, Ronco G, Villa P.

Eur J Pharm Sci. 1999 Jan;7(2):93-106.PMID: 9845786 [PubMed - indexed for MEDLINE]Related articles

Coexpression of erythroid and megakaryocytic genes in acute erythroblastic (FAB M6) and megakaryoblastic (FAB M7) leukaemias.

Linari S, Vannucchi AM, Ciolli S, Leoni F, Caporale R, Grossi A, Pagliai G, Santini V, Paoletti F, Ferrini PR.

Br J Haematol. 1998 Sep;102(5):1335-7.PMID: 9753066 [PubMed - indexed for MEDLINE]Related articles

Differentiation therapy of myelodysplastic syndromes: fact or fiction?

Santini V, Ferrini PR.

Br J Haematol. 1998 Sep;102(5):1124-38. Review. No abstract available. PMID: 9753034 [PubMed - indexed for MEDLINE]Related articles

Butyrate-stable monosaccharide derivatives induce maturation and apoptosis in human acute myeloid leukaemia cells.

Santini V, Scappini B, Gozzini A, Grossi A, Villa P, Ronco G, Douillet O, Pouillart P, Bernabei PA, Rossi Ferrini P.

Br J Haematol. 1998 Jun;101(3):529-38.PMID: 9633898 [PubMed - indexed for MEDLINE]Related articles

Proliferation signaling and activation of Shc, p21Ras, and Myc via tyrosine 764 of human granulocyte colony-stimulating factor receptor.

de Koning JP, Soede-Bobok AA, Schelen AM, Smith L, van Leeuwen D, Santini V, Burgering BM, Bos JL, Lowenberg B, Touw IP.

Blood. 1998 Mar 15;91(6):1924-33.PMID: 9490675 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic lesions associated with blastic transformation of polycythemia vera and essential thrombocythemia.

Gaidano G, Pastore C, Santini V, Nomdedeu J, Gamberi B, Capello D, Vischia F, Resegotti L, Mazza U, Ferrini PR, Lo Coco F, Saglio G.

Genes Chromosomes Cancer. 1997 Aug;19(4):250-5.PMID: 9258660 [PubMed - indexed for MEDLINE]Related articles

Apoptotic and antiproliferative effects of gemcitabine and gemcitabine plus Ara-C on blast cells from patients with blast crisis chronic myeloproliferative disorders.

Santini V, Bernabei A, Gozzini A, Scappini B, Zoccolante A, D'Ippolito G, Figuccia M, Ferrini PR.

Haematologica. 1997 Jan-Feb;82(1):11-5.PMID: 9172997 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of bcr/abl transcripts by RT-PCR and their colorimetric evaluation in chronic myeloid leukemia patients receiving allogeneic bone marrow transplantation.

Santini V, Zoccolante A, Bosi A, Guidi S, Saccardi R, Vannucchi AM, Martinazzo G, Bernabei PA, Ferrini PR.

Haematologica. 1996 May-Jun;81(3):201-7.PMID: 8767524 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of fludarabine and gemcitabine on human acute myeloid leukemia cell line HL 60: direct comparison of cytotoxicity and cellular Ara-C uptake enhancement.

Santini V, D'Ippolito G, Bernabei PA, Zoccolante A, Ermini A, Rossi-Ferrini P.

Leuk Res. 1996 Jan;20(1):37-45.PMID: 8632676 [PubMed - indexed for MEDLINE]Related articles