PubMed

Neurologic outcomes with cerebral oxygen monitoring in traumatic brain injury.

McCarthy MC, Moncrief H, Sands JM, Markert RJ, Hall LC, Wenker IC, Anderson HL 3rd, Ekeh AP, Walusimbi MS, Woods RJ, Saxe JM, Tchorz KM.

Surgery. 2009 Oct;146(4):585-90; discussion 590-1.PMID: 19789016 [PubMed - indexed for MEDLINE]Related articles

Geriatric nephrology: old or new subspecialty.

Schlanger LE, Bailey JL, Sands JM.

Clin Geriatr Med. 2009 Aug;25(3):311-24.PMID: 19765483 [PubMed - in process]Related articles

Epac regulates UT-A1 to increase urea transport in inner medullary collecting ducts.

Wang Y, Klein JD, Blount MA, Martin CF, Kent KJ, Pech V, Wall SM, Sands JM.

J Am Soc Nephrol. 2009 Sep;20(9):2018-24. Epub 2009 Aug 6.PMID: 19661162 [PubMed - indexed for MEDLINE]Related articles

The physiology of urinary concentration: an update.

Sands JM, Layton HE.

Semin Nephrol. 2009 May;29(3):178-95. Review.PMID: 19523568 [PubMed - indexed for MEDLINE]Related articles

Syntaxin specificity of aquaporins in the inner medullary collecting duct.

Mistry AC, Mallick R, Klein JD, Weimbs T, Sands JM, Fröhlich O.

Am J Physiol Renal Physiol. 2009 Aug;297(2):F292-300. Epub 2009 Jun 10.PMID: 19515809 [PubMed - indexed for MEDLINE]Related articles

Caveolin-1 directly interacts with UT-A1 urea transporter: the role of caveolae/lipid rafts in UT-A1 regulation at the cell membrane.

Feng X, Huang H, Yang Y, Fröhlich O, Klein JD, Sands JM, Chen G.

Am J Physiol Renal Physiol. 2009 Jun;296(6):F1514-20. Epub 2009 Apr 15.PMID: 19369293 [PubMed - indexed for MEDLINE]Related articles

Urea and NaCl regulate UT-A1 urea transporter in opposing directions via TonEBP pathway during osmotic diuresis.

Kim YM, Kim WY, Lee HW, Kim J, Kwon HM, Klein JD, Sands JM, Kim D.

Am J Physiol Renal Physiol. 2009 Jan;296(1):F67-77. Epub 2008 Oct 22.PMID: 18945830 [PubMed - indexed for MEDLINE]Related articles

Potential role of purinergic signaling in urinary concentration in inner medulla: insights from P2Y2 receptor gene knockout mice.

Zhang Y, Sands JM, Kohan DE, Nelson RD, Martin CF, Carlson NG, Kamerath CD, Ge Y, Klein JD, Kishore BK.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1715-24. Epub 2008 Oct 1.PMID: 18829742 [PubMed - indexed for MEDLINE]Related articles

MDM2 E3 ubiquitin ligase mediates UT-A1 urea transporter ubiquitination and degradation.

Chen G, Huang H, Fröhlich O, Yang Y, Klein JD, Price SR, Sands JM.

Am J Physiol Renal Physiol. 2008 Nov;295(5):F1528-34. Epub 2008 Sep 10.PMID: 18784257 [PubMed - indexed for MEDLINE]Related articlesFree article

Urea transporters UT-A1 and UT-A3 accumulate in the plasma membrane in response to increased hypertonicity.

Blessing NW, Blount MA, Sands JM, Martin CF, Klein JD.

Am J Physiol Renal Physiol. 2008 Nov;295(5):F1336-41. Epub 2008 Aug 20.PMID: 18715940 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of UT-A1 urea transporter at serines 486 and 499 is important for vasopressin-regulated activity and membrane accumulation.

Blount MA, Mistry AC, Fröhlich O, Price SR, Chen G, Sands JM, Klein JD.

Am J Physiol Renal Physiol. 2008 Jul;295(1):F295-9. Epub 2008 May 21.PMID: 18495802 [PubMed - indexed for MEDLINE]Related articlesFree article

Candesartan augments compensatory changes in medullary transport proteins in the diabetic rat kidney.

Blount MA, Sands JM, Kent KJ, Smith TD, Price SR, Klein JD.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1448-52. Epub 2008 Apr 16.PMID: 18417538 [PubMed - indexed for MEDLINE]Related articlesFree article

Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus.

Bedford JJ, Leader JP, Jing R, Walker LJ, Klein JD, Sands JM, Walker RJ.

Am J Physiol Renal Physiol. 2008 Apr;294(4):F812-20. Epub 2008 Jan 23.PMID: 18216143 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of UT-A1-mediated transepithelial urea flux in MDCK cells by lithium.

Fröhlich O, Aggarwal D, Klein JD, Kent KJ, Yang Y, Gunn RB, Sands JM.

Am J Physiol Renal Physiol. 2008 Mar;294(3):F518-24. Epub 2008 Jan 2.PMID: 18171999 [PubMed - indexed for MEDLINE]Related articlesFree article

The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein.

Mistry AC, Mallick R, Fröhlich O, Klein JD, Rehm A, Chen G, Sands JM.

J Biol Chem. 2007 Oct 12;282(41):30097-106. Epub 2007 Aug 16.PMID: 17702749 [PubMed - indexed for MEDLINE]Related articlesFree article

Forskolin stimulates phosphorylation and membrane accumulation of UT-A3.

Blount MA, Klein JD, Martin CF, Tchapyjnikov D, Sands JM.

Am J Physiol Renal Physiol. 2007 Oct;293(4):F1308-13. Epub 2007 Aug 8.PMID: 17686955 [PubMed - indexed for MEDLINE]Related articlesFree article

Downregulation of renal TonEBP in hypokalemic rats.

Jeon US, Han KH, Park SH, Lee SD, Sheen MR, Jung JY, Kim WY, Sands JM, Kim J, Kwon HM.

Am J Physiol Renal Physiol. 2007 Jul;293(1):F408-15. Epub 2007 Apr 4.PMID: 17409277 [PubMed - indexed for MEDLINE]Related articlesFree article

Adrenalectomy blocks the compensatory increases in UT-A1 and AQP2 in diabetic rat kidney.

Klein JD, Kozlowski S, Antoun TA, Sands JM.

J Membr Biol. 2006;212(2):139-44. Epub 2007 Jan 30.PMID: 17264983 [PubMed - indexed for MEDLINE]Related articles

Critical role of urea in the urine-concentrating mechanism.

Sands JM.

J Am Soc Nephrol. 2007 Mar;18(3):670-1. Epub 2007 Jan 24. No abstract available. PMID: 17251382 [PubMed - indexed for MEDLINE]Related articlesFree article

Significance of urea transport: the pioneering studies of Bodil Schmidt-Nielsen.

Kokko JP, Sands JM.

Am J Physiol Renal Physiol. 2006 Dec;291(6):F1109-12. No abstract available. PMID: 17082347 [PubMed - indexed for MEDLINE]Related articlesFree article

Vasopressin increases plasma membrane accumulation of urea transporter UT-A1 in rat inner medullary collecting ducts.

Klein JD, Fröhlich O, Blount MA, Martin CF, Smith TD, Sands JM.

J Am Soc Nephrol. 2006 Oct;17(10):2680-6. Epub 2006 Sep 7.PMID: 16959825 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of N-linked glycosylation reduces urea transporter UT-A1 response to vasopressin.

Chen G, Fröhlich O, Yang Y, Klein JD, Sands JM.

J Biol Chem. 2006 Sep 15;281(37):27436-42. Epub 2006 Jul 18.PMID: 16849333 [PubMed - indexed for MEDLINE]Related articlesFree article

Urea transporter UT-A1 and aquaporin-2 proteins decrease in response to angiotensin II or norepinephrine-induced acute hypertension.

Klein JD, Murrell BP, Tucker S, Kim YH, Sands JM.

Am J Physiol Renal Physiol. 2006 Nov;291(5):F952-9. Epub 2006 Jun 20.PMID: 16788141 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of UT-A1-mediated transepithelial urea flux in MDCK cells.

Fröhlich O, Klein JD, Smith PM, Sands JM, Gunn RB.

Am J Physiol Cell Physiol. 2006 Oct;291(4):C600-6. Epub 2006 Apr 26.PMID: 16641165 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of water restriction on gene expression in mouse renal medulla: identification of 3betaHSD4 as a collecting duct protein.

Cai Q, Keck M, McReynolds MR, Klein JD, Greer K, Sharma K, Hoying JB, Sands JM, Brooks HL.

Am J Physiol Renal Physiol. 2006 Jul;291(1):F218-24. Epub 2006 Feb 14.PMID: 16478974 [PubMed - indexed for MEDLINE]Related articlesFree article

Nephrogenic diabetes insipidus.

Sands JM, Bichet DG; American College of Physicians; American Physiological Society.

Ann Intern Med. 2006 Feb 7;144(3):186-94. Review. No abstract available. PMID: 16461963 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic restoration of aldose reductase to the collecting tubules restores maturation of the urine concentrating mechanism.

Yang JY, Tam WY, Tam S, Guo H, Wu X, Li G, Chau JF, Klein JD, Chung SK, Sands JM, Chung SS.

Am J Physiol Renal Physiol. 2006 Jul;291(1):F186-95. Epub 2006 Jan 31.PMID: 16449351 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in subcellular distribution of the ammonia transporter, Rhcg, in response to chronic metabolic acidosis.

Seshadri RM, Klein JD, Smith T, Sands JM, Handlogten ME, Verlander JW, Weiner ID.

Am J Physiol Renal Physiol. 2006 Jun;290(6):F1443-52. Epub 2006 Jan 24.PMID: 16434569 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue distribution of UT-A and UT-B mRNA and protein in rat.

Doran JJ, Klein JD, Kim YH, Smith TD, Kozlowski SD, Gunn RB, Sands JM.

Am J Physiol Regul Integr Comp Physiol. 2006 May;290(5):R1446-59. Epub 2005 Dec 22.PMID: 16373440 [PubMed - indexed for MEDLINE]Related articles

Ultrastructural localization of UT-A and UT-B in rat kidneys with different hydration status.

Lim SW, Han KH, Jung JY, Kim WY, Yang CW, Sands JM, Knepper MA, Madsen KM, Kim J.

Am J Physiol Regul Integr Comp Physiol. 2006 Feb;290(2):R479-92. Epub 2005 Sep 22.PMID: 16179486 [PubMed - indexed for MEDLINE]Related articles

Renal expression of the ammonia transporters, Rhbg and Rhcg, in response to chronic metabolic acidosis.

Seshadri RM, Klein JD, Kozlowski S, Sands JM, Kim YH, Han KH, Handlogten ME, Verlander JW, Weiner ID.

Am J Physiol Renal Physiol. 2006 Feb;290(2):F397-408. Epub 2005 Sep 6.PMID: 16144966 [PubMed - indexed for MEDLINE]Related articlesFree article

Vasopressin increases urea permeability in the initial IMCD from diabetic rats.

Pech V, Klein JD, Kozlowski SD, Wall SM, Sands JM.

Am J Physiol Renal Physiol. 2005 Sep;289(3):F531-5. Epub 2005 May 10.PMID: 15886274 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulated expression of renal and intestinal UT-B urea transporter in response to varying urea load.

Inoue H, Kozlowski SD, Klein JD, Bailey JL, Sands JM, Bagnasco SM.

Am J Physiol Renal Physiol. 2005 Aug;289(2):F451-8. Epub 2005 Mar 29.PMID: 15798087 [PubMed - indexed for MEDLINE]Related articlesFree article

Micropuncture: unlocking the secrets of renal function.

Sands JM.

Am J Physiol Renal Physiol. 2004 Nov;287(5):F866-7.PMID: 15475539 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel type of urea transporter, UT-C, is highly expressed in proximal tubule of seawater eel kidney.

Mistry AC, Chen G, Kato A, Nag K, Sands JM, Hirose S.

Am J Physiol Renal Physiol. 2005 Mar;288(3):F455-65. Epub 2004 Sep 21.PMID: 15383403 [PubMed - indexed for MEDLINE]Related articlesFree article

Renal urea transporters.

Sands JM.

Curr Opin Nephrol Hypertens. 2004 Sep;13(5):525-32. Review.PMID: 15300159 [PubMed - indexed for MEDLINE]Related articles

Urea may regulate urea transporter protein abundance during osmotic diuresis.

Kim D, Klein JD, Racine S, Murrell BP, Sands JM.

Am J Physiol Renal Physiol. 2005 Jan;288(1):F188-97. Epub 2004 Jul 13.PMID: 15251864 [PubMed - indexed for MEDLINE]Related articlesFree article

Upregulation of urea transporter UT-A2 and water channels AQP2 and AQP3 in mice lacking urea transporter UT-B.

Klein JD, Sands JM, Qian L, Wang X, Yang B.

J Am Soc Nephrol. 2004 May;15(5):1161-7.PMID: 15100356 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of nitrogen intake on nitrogen recycling and urea transporter abundance in lambs.

Marini JC, Klein JD, Sands JM, Van Amburgh ME.

J Anim Sci. 2004 Apr;82(4):1157-64.PMID: 15080338 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered expression of urea transporters in response to ureteral obstruction.

Li C, Klein JD, Wang W, Knepper MA, Nielsen S, Sands JM, Frøkiaer J.

Am J Physiol Renal Physiol. 2004 Jun;286(6):F1154-62. Epub 2004 Feb 24.PMID: 14982816 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldosterone decreases UT-A1 urea transporter expression via the mineralocorticoid receptor.

Gertner RA, Klein JD, Bailey JL, Kim DU, Luo XH, Bagnasco SM, Sands JM.

J Am Soc Nephrol. 2004 Mar;15(3):558-65.PMID: 14978157 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term treatment with cyclosporine decreases aquaporins and urea transporters in the rat kidney.

Lim SW, Li C, Sun BK, Han KH, Kim WY, Oh YW, Lee JU, Kador PF, Knepper MA, Sands JM, Kim J, Yang CW.

Am J Physiol Renal Physiol. 2004 Jul;287(1):F139-51. Epub 2004 Feb 10.PMID: 14871880 [PubMed - indexed for MEDLINE]Related articlesFree article

Urea transport in MDCK cells that are stably transfected with UT-A1.

Fröhlich O, Klein JD, Smith PM, Sands JM, Gunn RB.

Am J Physiol Cell Physiol. 2004 Jun;286(6):C1264-70. Epub 2004 Jan 28.PMID: 14749217 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of vasopressin in diabetes mellitus-induced changes in medullary transport proteins involved in urine concentration in Brattleboro rats.

Kim D, Sands JM, Klein JD.

Am J Physiol Renal Physiol. 2004 Apr;286(4):F760-6. Epub 2003 Nov 25.PMID: 14644754 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunohistochemical localization of urea transporters A and B in the rat cochlea.

Kwun YS, Yeo SW, Ahn YH, Lim SW, Jung JY, Kim WY, Sands JM, Kim J.

Hear Res. 2003 Sep;183(1-2):84-96.PMID: 13679141 [PubMed - indexed for MEDLINE]Related articles

Expression of urea transporters in potassium-depleted mouse kidney.

Jung JY, Madsen KM, Han KH, Yang CW, Knepper MA, Sands JM, Kim J.

Am J Physiol Renal Physiol. 2003 Dec;285(6):F1210-24. Epub 2003 Sep 2.PMID: 12952854 [PubMed - indexed for MEDLINE]Related articlesFree article

Urine-concentrating ability in the aging kidney.

Sands JM.

Sci Aging Knowledge Environ. 2003 Jun 18;2003(24):PE15.PMID: 12844542 [PubMed - indexed for MEDLINE]Related articles

Changes in renal medullary transport proteins during uncontrolled diabetes mellitus in rats.

Kim D, Sands JM, Klein JD.

Am J Physiol Renal Physiol. 2003 Aug;285(2):F303-9. Epub 2003 Apr 15.PMID: 12697581 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mechanisms of urea transport.

Sands JM.

J Membr Biol. 2003 Feb 1;191(3):149-63. Review.PMID: 12571750 [PubMed - indexed for MEDLINE]Related articles

Mammalian urea transporters.

Sands JM.

Annu Rev Physiol. 2003;65:543-66. Epub 2002 May 1. Review.PMID: 12524463 [PubMed - indexed for MEDLINE]Related articles