PubMed

Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo.

Kenski DM, Cooper AJ, Li JJ, Willingham AT, Haringsma HJ, Young TA, Kuklin NA, Jones JJ, Cancilla MT, McMasters DR, Mathur M, Sachs AB, Flanagan WM.

Nucleic Acids Res. 2009 Nov 16. [Epub ahead of print]PMID: 19917641 [PubMed - as supplied by publisher]Related articlesFree article

Health care reform update.

Sachs A.

Am Nurse. 2009 Sep-Oct;41(5):1, 9. No abstract available. PMID: 19866551 [PubMed - in process]Related articles

Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment.

Abrams MT, Koser ML, Seitzer J, Williams SC, Dipietro MA, Wang W, Shaw AW, Mao X, Jadhav V, Davide JP, Burke PA, Sachs AB, Stirdivant SM, Sepp-Lorenzino L.

Mol Ther. 2009 Sep 8. [Epub ahead of print]PMID: 19738601 [PubMed - as supplied by publisher]Related articles

The diagnostic value of history and physical examination for COPD in suspected or known cases: a systematic review.

Broekhuizen BD, Sachs AP, Oostvogels R, Hoes AW, Verheij TJ, Moons KG.

Fam Pract. 2009 Aug;26(4):260-8. Epub 2009 May 7.PMID: 19423699 [PubMed - indexed for MEDLINE]Related articles

Nr2e3-directed transcriptional regulation of genes involved in photoreceptor development and cell-type specific phototransduction.

Haider NB, Mollema N, Gaule M, Yuan Y, Sachs AJ, Nystuen AM, Naggert JK, Nishina PM.

Exp Eye Res. 2009 Sep;89(3):365-72. Epub 2009 Apr 18. Review.PMID: 19379737 [PubMed - indexed for MEDLINE]Related articles

The other kind of downsizing. Losing weight in a recession is harder than you think.

Sachs A.

Time. 2009 Jan 12;173(1):47-8. No abstract available. PMID: 19209480 [PubMed - indexed for MEDLINE]Related articles

MicroRNA-like off-target transcript regulation by siRNAs is species specific.

Burchard J, Jackson AL, Malkov V, Needham RH, Tan Y, Bartz SR, Dai H, Sachs AB, Linsley PS.

RNA. 2009 Feb;15(2):308-15.PMID: 19144911 [PubMed - indexed for MEDLINE]Related articlesFree article

[How does the German DRG system differentiate and reimburse vitreoretinal surgery in diabetic patients?]

Krause M, Goldschmidt AJ, Berg M, Kropf S, Sachs A, Gatzioufas Z, Brückner K, Seitz B.

Klin Monbl Augenheilkd. 2008 Oct;225(10):880-7. Epub 2008 Oct 24. German. PMID: 18951309 [PubMed - indexed for MEDLINE]Related articles

LC-MS/MS analysis of differential centrifugation fractions from native inner medullary collecting duct of rat.

Sachs AN, Pisitkun T, Hoffert JD, Yu MJ, Knepper MA.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1799-806. Epub 2008 Oct 15.PMID: 18922883 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of novel trophoblast invasion-related genes: heme oxygenase-1 controls motility via peroxisome proliferator-activated receptor gamma.

Bilban M, Haslinger P, Prast J, Klinglmüller F, Woelfel T, Haider S, Sachs A, Otterbein LE, Desoye G, Hiden U, Wagner O, Knöfler M.

Endocrinology. 2009 Feb;150(2):1000-13. Epub 2008 Oct 9.PMID: 18845641 [PubMed - indexed for MEDLINE]Related articles

A novel mutation in Prph2, a gene regulated by Nr2e3, causes retinal degeneration and outer-segment defects similar to Nr2e3 ( rd7/rd7 ) retinas.

Nystuen AM, Sachs AJ, Yuan Y, Heuermann L, Haider NB.

Mamm Genome. 2008 Sep;19(9):623-33. Epub 2008 Sep 3.PMID: 18763016 [PubMed - indexed for MEDLINE]Related articles

Clinical value of anthropometric estimates of leg lean volume in nutritionally depleted and non-depleted patients with chronic obstructive pulmonary disease.

Villaça DS, Lerario MC, dal Corso S, Nápolis L, de Albuquerque AL, Lazaretti-Castro M, Sachs A, Nery LE, Neder JA.

Br J Nutr. 2008 Aug;100(2):380-6. Epub 2008 Jan 10.PMID: 18184453 [PubMed - indexed for MEDLINE]Related articles

Enhanced severity of virus associated lower respiratory tract disease in asthma patients may not be associated with delayed viral clearance and increased viral load in the upper respiratory tract.

van Elden LJ, Sachs AP, van Loon AM, Haarman M, van de Vijver DA, Kimman TG, Zuithoff P, Schipper PJ, Verheij TJ, Nijhuis M.

J Clin Virol. 2008 Feb;41(2):116-21. Epub 2007 Dec 21.PMID: 18096430 [PubMed - indexed for MEDLINE]Related articles

[Summary of the practice guideline 'allergic and non-allergic rhinitis' (first revision) from the Dutch College of General Practitioners]

van Balen JA, Verduijn MM, Sachs AP, Berger MY, Lucassen PL, Wiersma TJ, Goudswaard AN.

Ned Tijdschr Geneeskd. 2007 Oct 13;151(41):2261-5. Review. Dutch. PMID: 17987893 [PubMed - indexed for MEDLINE]Related articles

The mouse mutants recoil wobbler and nmf373 represent a series of Grm1 mutations.

Sachs AJ, Schwendinger JK, Yang AW, Haider NB, Nystuen AM.

Mamm Genome. 2007 Nov;18(11):749-56. Epub 2007 Oct 13.PMID: 17934773 [PubMed - indexed for MEDLINE]Related articles

Quality of life in smokers: focus on functional limitations rather than on lung function?

Geijer RM, Sachs AP, Verheij TJ, Kerstjens HA, Kuyvenhoven MM, Hoes AW.

Br J Gen Pract. 2007 Jun;57(539):477-82.PMID: 17550673 [PubMed - indexed for MEDLINE]Related articlesFree article

Are patient characteristics helpful in recognizing mild COPD (GOLD I) in daily practice?

Geijer RM, Sachs AP, Verheij TJ, Lammers JW, Salomé PL, Hoes AW.

Scand J Prim Health Care. 2006 Dec;24(4):237-42.PMID: 17118864 [PubMed - indexed for MEDLINE]Related articles

A null mutation in VAMP1/synaptobrevin is associated with neurological defects and prewean mortality in the lethal-wasting mouse mutant.

Nystuen AM, Schwendinger JK, Sachs AJ, Yang AW, Haider NB.

Neurogenetics. 2007 Jan;8(1):1-10. Epub 2006 Nov 11.PMID: 17102983 [PubMed - indexed for MEDLINE]Related articles

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.

Majercak J, Ray WJ, Espeseth A, Simon A, Shi XP, Wolffe C, Getty K, Marine S, Stec E, Ferrer M, Strulovici B, Bartz S, Gates A, Xu M, Huang Q, Ma L, Shughrue P, Burchard J, Colussi D, Pietrak B, Kahana J, Beher D, Rosahl T, Shearman M, Hazuda D, Sachs AB, Koblan KS, Seabrook GR, Stone DJ.

Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17967-72. Epub 2006 Nov 10.PMID: 17098871 [PubMed - indexed for MEDLINE]Related articlesFree article

Incidence and determinants of moderate COPD (GOLD II) in male smokers aged 40-65 years: 5-year follow up.

Geijer RM, Sachs AP, Verheij TJ, Salomé PL, Lammers JW, Hoes AW.

Br J Gen Pract. 2006 Sep;56(530):656-61.PMID: 16953996 [PubMed - indexed for MEDLINE]Related articlesFree article

Chest radiography in general practice: indications, diagnostic yield and consequences for patient management.

Speets AM, van der Graaf Y, Hoes AW, Kalmijn S, Sachs AP, Rutten MJ, Gratama JW, Montauban van Swijndregt AD, Mali WP.

Br J Gen Pract. 2006 Aug;56(529):574-8.PMID: 16882374 [PubMed - indexed for MEDLINE]Related articlesFree article

Body composition in patients with chronic obstructive pulmonary disease: which method to use in clinical practice?

Lerario MC, Sachs A, Lazaretti-Castro M, Saraiva LG, Jardim JR.

Br J Nutr. 2006 Jul;96(1):86-92.PMID: 16869995 [PubMed - indexed for MEDLINE]Related articles

Chest radiography and pneumonia in primary care: diagnostic yield and consequences for patient management.

Speets AM, Hoes AW, van der Graaf Y, Kalmijn S, Sachs AP, Mali WP.

Eur Respir J. 2006 Nov;28(5):933-8. Epub 2006 Jul 12.PMID: 16837505 [PubMed - indexed for MEDLINE]Related articlesFree article

[Optimizing the antibiotics policy in The Netherlands. VIII. Revised SWAB guidelines for antimicrobial therapy in adults with community-acquired pneumonia]

Schouten JA, Prins JM, Bonten M, Degener JE, Janknegt R, Hollander JM, Jonkers R, Wijnands W, Verheij T, Sachs A, Kullberg BJ.

Ned Tijdschr Geneeskd. 2005 Nov 5;149(45):2495-500. Review. Dutch. PMID: 16304886 [PubMed - indexed for MEDLINE]Related articles

Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment.

Simon JS, Karnoub MC, Devlin DJ, Arreaza MG, Qiu P, Monks SA, Severino ME, Deutsch P, Palmisano J, Sachs AB, Bayne ML, Plump AS, Schadt EE.

Genomics. 2005 Dec;86(6):648-56. Epub 2005 Nov 16.PMID: 16297596 [PubMed - indexed for MEDLINE]Related articles

Skin biopsies for the measurement of clinical pharmacodynamic biomarkers.

Phillips RL, Sachs AB.

Curr Opin Biotechnol. 2005 Dec;16(6):687-90. Epub 2005 Oct 28. Review.PMID: 16257524 [PubMed - indexed for MEDLINE]Related articles

Revised SWAB guidelines for antimicrobial therapy of community-acquired pneumonia.

Schouten JA, Prins JM, Bonten MJ, Degener J, Janknegt RE, Hollander JM, Jonkers RE, Wijnands WJ, Verheij TJ, Sachs AP, Kullberg BJ; Dutch Working Party on Antibiotic Policy.

Neth J Med. 2005 Sep;63(8):323-35. Review.PMID: 16186645 [PubMed - indexed for MEDLINE]Related articlesFree article

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels.

Cervino AC, Li G, Edwards S, Zhu J, Laurie C, Tokiwa G, Lum PY, Wang S, Castellani LW, Lusis AJ, Carlson S, Sachs AB, Schadt EE.

Genomics. 2005 Nov;86(5):505-17. Epub 2005 Aug 29. Erratum in: Genomics. 2009 Apr;93(4):399. Castellini, Lawrence W [corrected to Castellani, Lawrence W]. PMID: 16126366 [PubMed - indexed for MEDLINE]Related articles

Embracing complexity, inching closer to reality.

Schadt EE, Sachs A, Friend S.

Sci STKE. 2005 Aug 2;2005(295):pe40. Review.PMID: 16077086 [PubMed - indexed for MEDLINE]Related articles

An integrative genomics approach to infer causal associations between gene expression and disease.

Schadt EE, Lamb J, Yang X, Zhu J, Edwards S, Guhathakurta D, Sieberts SK, Monks S, Reitman M, Zhang C, Lum PY, Leonardson A, Thieringer R, Metzger JM, Yang L, Castle J, Zhu H, Kash SF, Drake TA, Sachs A, Lusis AJ.

Nat Genet. 2005 Jul;37(7):710-7. Epub 2005 Jun 19.PMID: 15965475 [PubMed - indexed for MEDLINE]Related articles

Prevalence of undetected persistent airflow obstruction in male smokers 40-65 years old.

Geijer RM, Sachs AP, Hoes AW, Salomé PL, Lammers JW, Verheij TJ.

Fam Pract. 2005 Oct;22(5):485-9. Epub 2005 Jun 17.PMID: 15964866 [PubMed - indexed for MEDLINE]Related articlesFree article

A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients.

Dai H, van't Veer L, Lamb J, He YD, Mao M, Fine BM, Bernards R, van de Vijver M, Deutsch P, Sachs A, Stoughton R, Friend S.

Cancer Res. 2005 May 15;65(10):4059-66.PMID: 15899795 [PubMed - indexed for MEDLINE]Related articlesFree article

Unrecognized heart failure in elderly patients with stable chronic obstructive pulmonary disease.

Rutten FH, Cramer MJ, Grobbee DE, Sachs AP, Kirkels JH, Lammers JW, Hoes AW.

Eur Heart J. 2005 Sep;26(18):1887-94. Epub 2005 Apr 28.PMID: 15860516 [PubMed - indexed for MEDLINE]Related articlesFree article

How the petite eat.

Sachs A.

Time. 2005 Jan 24;165(4):67. No abstract available. PMID: 15700710 [PubMed - indexed for MEDLINE]Related articles

Towards functional transplant donor matching by measurement of granzyme A and granzyme B production levels.

Kircher B, Hack CE, Dickinson AM, Wang XN, Oudshoorn M, Sachs A, Wolbink A, Niederwieser D, Eibl GJ, van Houwelingen HC, Goulmy E.

J Immunol Methods. 2004 Oct;293(1-2):51-9.PMID: 15541276 [PubMed - indexed for MEDLINE]Related articles

Genetic inheritance of gene expression in human cell lines.

Monks SA, Leonardson A, Zhu H, Cundiff P, Pietrusiak P, Edwards S, Phillips JW, Sachs A, Schadt EE.

Am J Hum Genet. 2004 Dec;75(6):1094-105. Epub 2004 Oct 21.PMID: 15514893 [PubMed - indexed for MEDLINE]Related articlesFree article

An integrative genomics approach to the reconstruction of gene networks in segregating populations.

Zhu J, Lum PY, Lamb J, GuhaThakurta D, Edwards SW, Thieringer R, Berger JP, Wu MS, Thompson J, Sachs AB, Schadt EE.

Cytogenet Genome Res. 2004;105(2-4):363-74.PMID: 15237224 [PubMed - indexed for MEDLINE]Related articles

Loss of translational control in yeast compromised for the major mRNA decay pathway.

Holmes LE, Campbell SG, De Long SK, Sachs AB, Ashe MP.

Mol Cell Biol. 2004 Apr;24(7):2998-3010.PMID: 15024087 [PubMed - indexed for MEDLINE]Related articlesFree article

Psychophysical receptive fields of edge detection mechanisms.

Elder JH, Sachs AJ.

Vision Res. 2004 Apr;44(8):795-813.PMID: 14967206 [PubMed - indexed for MEDLINE]Related articles

Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.

Gross JD, Moerke NJ, von der Haar T, Lugovskoy AA, Sachs AB, McCarthy JE, Wagner G.

Cell. 2003 Dec 12;115(6):739-50.PMID: 14675538 [PubMed - indexed for MEDLINE]Related articles

Is asthma in 2-12 year-old children associated with physician-attended recurrent upper respiratory tract infections?

Hak E, Rovers MM, Sachs AP, Stalman WA, Verheij TJ.

Eur J Epidemiol. 2003;18(9):899-902.PMID: 14561050 [PubMed - indexed for MEDLINE]Related articles

Interactions of the eukaryotic translation initiation factor eIF4E.

Gross JD, Matsuo H, Fletcher M, Sachs AB, Wagner G.

Cold Spring Harb Symp Quant Biol. 2001;66:397-402. Review. No abstract available. PMID: 12762042 [PubMed - indexed for MEDLINE]Related articles

Panic control treatment for agoraphobia.

Craske MG, DeCola JP, Sachs AD, Pontillo DC.

J Anxiety Disord. 2003;17(3):321-33.PMID: 12727125 [PubMed - indexed for MEDLINE]Related articles

The other side of the world. Why does anyone care about sustainability?

Sachs A.

World Watch. 1998 May-Jun;11(3):31-8.PMID: 12293665 [PubMed - indexed for MEDLINE]Related articles

One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs.

Inada T, Winstall E, Tarun SZ Jr, Yates JR 3rd, Schieltz D, Sachs AB.

RNA. 2002 Jul;8(7):948-58.PMID: 12166649 [PubMed - indexed for MEDLINE]Related articlesFree article

Development and characterization of a reconstituted yeast translation initiation system.

Algire MA, Maag D, Savio P, Acker MG, Tarun SZ Jr, Sachs AB, Asano K, Nielsen KH, Olsen DS, Phan L, Hinnebusch AG, Lorsch JR.

RNA. 2002 Mar;8(3):382-97.PMID: 12008673 [PubMed - indexed for MEDLINE]Related articlesFree article

Fixing the rift.

Sachs A.

Time. 2002 Apr 15;159(15):F9. No abstract available. PMID: 11975009 [PubMed - indexed for MEDLINE]Related articles

Appropriate antibiotic use for acute pharyngitis.

Zwart S, Sachs A.

Ann Intern Med. 2002 Apr 16;136(8):632-3; author reply 632-3. No abstract available. PMID: 11955037 [PubMed - indexed for MEDLINE]Related articlesFree article

[Meningococcal disease in the Netherlands: media hype, but not an epidemic]

Zwart S, Sachs AP.

Ned Tijdschr Geneeskd. 2001 Nov 17;145(46):2253. Dutch. No abstract available. PMID: 11757253 [PubMed - indexed for MEDLINE]Related articles

New ways of initiating translation in eukaryotes.

Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donzé O, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M Jr, Gehrke L, Goldman E, Groner Y, Harford JB, Hatzglou M, He B, Hellen CU, Hentze MW, Hershey J, Hershey P, Hohn T, Holcik M, Hunter CP, Igarashi K, Jackson R, Jagus R, Jefferson LS, Joshi B, Kaempfer R, Katze M, Kaufman RJ, Kiledjian M, Kimball SR, Kimchi A, Kirkegaard K, Koromilas AE, Krug RM, Kruys V, Lamphear BJ, Lemon S, Lloyd RE, Maquat LE, Martinez-Salas E, Mathews MB, Mauro VP, Miyamoto S, Mohr I, Morris DR, Moss EG, Nakashima N, Palmenberg A, Parkin NT, Pe'ery T, Pelletier J, Peltz S, Pestova TV, Pilipenko EV, Prats AC, Racaniello V, Read GS, Rhoads RE, Richter JD, Rivera-Pomar R, Rouault T, Sachs A, Sarnow P, Scheper GC, Schiff L, Schoenberg DR, Semler BL, Siddiqui A, Skern T, Sonenberg N, Sossin W, Standart N, Tahara SM, Thomas AA, Toulmé JJ, Wilusz J, Wimmer E, Witherell G, Wormington M.

Mol Cell Biol. 2001 Dec;21(23):8238-46. No abstract available. PMID: 11710333 [PubMed - indexed for MEDLINE]Related articlesFree article