PubMed

Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the family investigation of nephropathy and diabetes research group.

Malhotra A, Igo RP Jr, Thameem F, Kao WH, Abboud HE, Adler SG, Arar NH, Bowden DW, Duggirala R, Freedman BI, Goddard KA, Ipp E, Iyengar SK, Kimmel PL, Knowler WC, Kohn O, Leehey D, Meoni LA, Nelson RG, Nicholas SB, Parekh RS, Rich SS, Chen YD, Saad MF, Scavini M, Schelling JR, Sedor JR, Shah VO, Taylor KD, Thornley-Brown D, Zager PG, Horvath A, Hanson RL; Family Investigation of Nephropathy and Diabetes Research Group.

Diabetes Metab Res Rev. 2009 Nov;25(8):740-7.PMID: 19795399 [PubMed - in process]Related articles

Associations of inflammatory markers with coronary artery calcification: Results from the Multi-Ethnic Study of Atherosclerosis.

Jenny NS, Brown ER, Detrano R, Folsom AR, Saad MF, Shea S, Szklo M, Herrington DM, Jacobs DR Jr.

Atherosclerosis. 2009 Aug 28. [Epub ahead of print]PMID: 19766217 [PubMed - as supplied by publisher]Related articles

Ethnicity and sex modify the association of serum c-reactive protein with microalbuminuria.

Palmas W, Ma S, Jacobs DR Jr, Arnett D, Jackson S, Olson J, Saad MF, Kronmal R, Kramer H, Barr RG.

Ethn Dis. 2008 Summer;18(3):324-9.PMID: 18785447 [PubMed - indexed for MEDLINE]Related articles

Heritability of the severity of diabetic retinopathy: the FIND-Eye study.

Arar NH, Freedman BI, Adler SG, Iyengar SK, Chew EY, Davis MD, Satko SG, Bowden DW, Duggirala R, Elston RC, Guo X, Hanson RL, Igo RP Jr, Ipp E, Kimmel PL, Knowler WC, Molineros J, Nelson RG, Pahl MV, Quade SR, Rasooly RS, Rotter JI, Saad MF, Scavini M, Schelling JR, Sedor JR, Shah VO, Zager PG, Abboud HE; Family Investigation of Nephropathy and Diabetes Research Group.

Invest Ophthalmol Vis Sci. 2008 Sep;49(9):3839-45.PMID: 18765632 [PubMed - indexed for MEDLINE]Related articlesFree article

Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis.

Klein R, Knudtson MD, Klein BE, Wong TY, Cotch MF, Liu K, Cheng CY, Burke GL, Saad MF, Jacobs DR Jr, Sharrett AR.

Ophthalmology. 2008 Oct;115(10):1742-9. Epub 2008 Jun 5.PMID: 18538409 [PubMed - indexed for MEDLINE]Related articles

Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND).

Schelling JR, Abboud HE, Nicholas SB, Pahl MV, Sedor JR, Adler SG, Arar NH, Bowden DW, Elston RC, Freedman BI, Goddard KA, Guo X, Hanson RL, Ipp E, Iyengar SK, Jun G, Kao WH, Kasinath BS, Kimmel PL, Klag MJ, Knowler WC, Nelson RG, Parekh RS, Quade SR, Rich SS, Saad MF, Scavini M, Smith MW, Taylor K, Winkler CA, Zager PG, Shah VO; Family Investigation of Nephropathy and Diabetes Research Group.

Diabetes. 2008 Jan;57(1):235-43. Epub 2007 Nov 14.PMID: 18003762 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance, metabolic syndrome, and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis (MESA).

Bertoni AG, Wong ND, Shea S, Ma S, Liu K, Preethi S, Jacobs DR Jr, Wu C, Saad MF, Szklo M.

Diabetes Care. 2007 Nov;30(11):2951-6. Epub 2007 Aug 17.PMID: 17704348 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations of adiponectin with body fat distribution and insulin sensitivity in nondiabetic Hispanics and African-Americans.

Hanley AJ, Bowden D, Wagenknecht LE, Balasubramanyam A, Langfeld C, Saad MF, Rotter JI, Guo X, Chen YD, Bryer-Ash M, Norris JM, Haffner SM.

J Clin Endocrinol Metab. 2007 Jul;92(7):2665-71. Epub 2007 Apr 10.PMID: 17426091 [PubMed - indexed for MEDLINE]Related articlesFree article

Subclinical atherosclerotic cardiovascular disease and early age-related macular degeneration in a multiracial cohort: the Multiethnic Study of Atherosclerosis.

Klein R, Klein BE, Knudtson MD, Cotch MF, Wong TY, Liu K, Burke GL, Saad MF, Jacobs DR Jr, Sharrett AR.

Arch Ophthalmol. 2007 Apr;125(4):534-43.PMID: 17420374 [PubMed - indexed for MEDLINE]Related articlesFree article

Ethnic differences in the relationship of carotid atherosclerosis to coronary calcification: the Multi-Ethnic Study of Atherosclerosis.

Manolio TA, Arnold AM, Post W, Bertoni AG, Schreiner PJ, Sacco RL, Saad MF, Detrano RL, Szklo M.

Atherosclerosis. 2008 Mar;197(1):132-8. Epub 2007 Apr 6.PMID: 17412347 [PubMed - indexed for MEDLINE]Related articlesFree article

The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study.

Sale MM, Hsu FC, Palmer ND, Gordon CJ, Keene KL, Borgerink HM, Sharma AJ, Bergman RN, Taylor KD, Saad MF, Norris JM.

BMC Endocr Disord. 2007 Mar 30;7:1.PMID: 17397545 [PubMed]Related articlesFree article

Change in body size and the risk of colorectal adenomas.

Sedjo RL, Byers T, Levin TR, Haffner SM, Saad MF, Tooze JA, D'Agostino RB Jr.

Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):526-31.PMID: 17372248 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND).

Iyengar SK, Abboud HE, Goddard KA, Saad MF, Adler SG, Arar NH, Bowden DW, Duggirala R, Elston RC, Hanson RL, Ipp E, Kao WH, Kimmel PL, Klag MJ, Knowler WC, Meoni LA, Nelson RG, Nicholas SB, Pahl MV, Parekh RS, Quade SR, Rich SS, Rotter JI, Scavini M, Schelling JR, Sedor JR, Sehgal AR, Shah VO, Smith MW, Taylor KD, Winkler CA, Zager PG, Freedman BI; Family Investigation of Nephropathy and Diabetes Research Group.

Diabetes. 2007 Jun;56(6):1577-85. Epub 2007 Mar 15.PMID: 17363742 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipin deficiency impairs diurnal metabolic fuel switching.

Xu J, Lee WN, Phan J, Saad MF, Reue K, Kurland IJ.

Diabetes. 2006 Dec;55(12):3429-38.PMID: 17130489 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased hepatic futile cycling compensates for increased glucose disposal in the Pten heterodeficient mouse.

Xu J, Gowen L, Raphalides C, Hoyer KK, Weinger JG, Renard M, Troke JJ, Vaitheesyaran B, Lee WN, Saad MF, Sleeman MW, Teitell MA, Kurland IJ.

Diabetes. 2006 Dec;55(12):3372-80.PMID: 17130482 [PubMed - indexed for MEDLINE]Related articlesFree article

Feasibility of automating insulin delivery for the treatment of type 1 diabetes.

Steil GM, Rebrin K, Darwin C, Hariri F, Saad MF.

Diabetes. 2006 Dec;55(12):3344-50.PMID: 17130478 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between levels of blood pressure and measures of subclinical disease multi-ethnic study of atherosclerosis.

Psaty BM, Arnold AM, Olson J, Saad MF, Shea S, Post W, Burke GL.

Am J Hypertens. 2006 Nov;19(11):1110-7.PMID: 17070420 [PubMed - indexed for MEDLINE]Related articles

LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA).

Mora S, Szklo M, Otvos JD, Greenland P, Psaty BM, Goff DC Jr, O'Leary DH, Saad MF, Tsai MY, Sharrett AR.

Atherosclerosis. 2007 May;192(1):211-7.PMID: 16765964 [PubMed - indexed for MEDLINE]Related articles

Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study.

Guo X, Saad MF, Langefeld CD, Williams AH, Cui J, Taylor KD, Norris JM, Jinagouda S, Darwin CH, Mitchell BD, Bergman RN, Sutton B, Chen YD, Wagenknecht LE, Bowden DW, Rotter JI.

Diabetes. 2006 Jun;55(6):1723-30.PMID: 16731835 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypertension and smoking are associated with reduced regional left ventricular function in asymptomatic: individuals the Multi-Ethnic Study of Atherosclerosis.

Rosen BD, Saad MF, Shea S, Nasir K, Edvardsen T, Burke G, Jerosch-Herold M, Arnett DK, Lai S, Bluemke DA, Lima JA.

J Am Coll Cardiol. 2006 Mar 21;47(6):1150-8. Epub 2006 Feb 23.PMID: 16545644 [PubMed - indexed for MEDLINE]Related articles

Prevalence of age-related macular degeneration in 4 racial/ethnic groups in the multi-ethnic study of atherosclerosis.

Klein R, Klein BE, Knudtson MD, Wong TY, Cotch MF, Liu K, Burke G, Saad MF, Jacobs DR Jr.

Ophthalmology. 2006 Mar;113(3):373-80.PMID: 16513455 [PubMed - indexed for MEDLINE]Related articles

Diabetic cardiomyopathy and subclinical cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis (MESA).

Bertoni AG, Goff DC Jr, D'Agostino RB Jr, Liu K, Hundley WG, Lima JA, Polak JF, Saad MF, Szklo M, Tracy RP, Siscovick DS.

Diabetes Care. 2006 Mar;29(3):588-94.PMID: 16505511 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of proopiomelanocortin gene polymorphisms with obesity in the IRAS family study.

Sutton BS, Langefeld CD, Williams AH, Norris JM, Saad MF, Haffner SM, Bowden DW.

Obes Res. 2005 Sep;13(9):1491-8.PMID: 16222047 [PubMed - indexed for MEDLINE]Related articles

Smoking, diabetes, and blood cholesterol differ in their associations with subclinical atherosclerosis: the Multiethnic Study of Atherosclerosis (MESA).

Sharrett AR, Ding J, Criqui MH, Saad MF, Liu K, Polak JF, Folsom AR, Tsai MY, Burke GL, Szklo M.

Atherosclerosis. 2006 Jun;186(2):441-7. Epub 2005 Sep 9.PMID: 16154575 [PubMed - indexed for MEDLINE]Related articles

Effects of liraglutide (NN2211), a long-acting GLP-1 analogue, on glycaemic control and bodyweight in subjects with Type 2 diabetes.

Feinglos MN, Saad MF, Pi-Sunyer FX, An B, Santiago O; Liraglutide Dose-Response Study Group.

Diabet Med. 2005 Aug;22(8):1016-23.PMID: 16026367 [PubMed - indexed for MEDLINE]Related articles

Interstitial fluid glucose dynamics during insulin-induced hypoglycaemia.

Steil GM, Rebrin K, Hariri F, Jinagonda S, Tadros S, Darwin C, Saad MF.

Diabetologia. 2005 Sep;48(9):1833-40. Epub 2005 Jul 7.PMID: 16001232 [PubMed - indexed for MEDLINE]Related articles

Ankle-brachial index and subclinical cardiac and carotid disease: the multi-ethnic study of atherosclerosis.

McDermott MM, Liu K, Criqui MH, Ruth K, Goff D, Saad MF, Wu C, Homma S, Sharrett AR.

Am J Epidemiol. 2005 Jul 1;162(1):33-41.PMID: 15961584 [PubMed - indexed for MEDLINE]Related articlesFree article

Urine albumin excretion and subclinical cardiovascular disease. The Multi-Ethnic Study of Atherosclerosis.

Kramer H, Jacobs DR Jr, Bild D, Post W, Saad MF, Detrano R, Tracy R, Cooper R, Liu K.

Hypertension. 2005 Jul;46(1):38-43. Epub 2005 Jun 13.PMID: 15956113 [PubMed - indexed for MEDLINE]Related articlesFree article

Cosegregation of albuminuria and blood pressure: the Insulin Resistance Atherosclerosis (IRAS) family study.

Guo X, Cui J, Wagenknecht LE, Norris JM, Haffner SM, Darwin C, Jinagouda S, Rotter JI, Saad MF.

Am J Hypertens. 2005 Jun;18(6):823-7.PMID: 15925742 [PubMed - indexed for MEDLINE]Related articles

Genetic analysis of adiponectin and obesity in Hispanic families: the IRAS Family Study.

Sutton BS, Weinert S, Langefeld CD, Williams AH, Campbell JK, Saad MF, Haffner SM, Norris JM, Bowden DW.

Hum Genet. 2005 Jul;117(2-3):107-18. Epub 2005 Apr 21.PMID: 15843989 [PubMed - indexed for MEDLINE]Related articles

Abdominal obesity predicts declining insulin sensitivity in non-obese normoglycaemics: the Insulin Resistance Atherosclerosis Study (IRAS).

Karter AJ, D'Agostino RB Jr, Mayer-Davis EJ, Wagenknecht LE, Hanley AJ, Hamman RF, Bergman R, Saad MF, Haffner SM; IRAS investigators.

Diabetes Obes Metab. 2005 May;7(3):230-8.PMID: 15811139 [PubMed - indexed for MEDLINE]Related articles

Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study.

Goodarzi MO, Taylor KD, Guo X, Quiñones MJ, Cui J, Li Y, Saad MF, Yang H, Hsueh WA, Hodis HN, Rotter JI.

Diabetes. 2005 Apr;54(4):1228-32.PMID: 15793266 [PubMed - indexed for MEDLINE]Related articlesFree article

Ethnic differences in coronary calcification: the Multi-Ethnic Study of Atherosclerosis (MESA).

Bild DE, Detrano R, Peterson D, Guerci A, Liu K, Shahar E, Ouyang P, Jackson S, Saad MF.

Circulation. 2005 Mar 15;111(10):1313-20.PMID: 15769774 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of adipose tissue deposition and beta-2 adrenergic receptor variants: the IRAS family study.

Lange LA, Norris JM, Langefeld CD, Nicklas BJ, Wagenknecht LE, Saad MF, Bowden DW.

Int J Obes (Lond). 2005 May;29(5):449-57.PMID: 15672110 [PubMed - indexed for MEDLINE]Related articles

A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family study.

Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Hedrick CC, Wagenknecht LE, Bergman RN; Insulin Resistance Atherosclerosis Study (IRAS) Family Study.

Diabetes. 2005 Jan;54(1):290-5.PMID: 15616041 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study.

Norris JM, Langefeld CD, Scherzinger AL, Rich SS, Bookman E, Beck SR, Saad MF, Haffner SM, Bergman RN, Bowden DW, Wagenknecht LE.

Int J Obes (Lond). 2005 Jan;29(1):67-77.PMID: 15534617 [PubMed - indexed for MEDLINE]Related articles

Association analysis of the plasminogen activator inhibitor-1 4G/5G polymorphism in Hispanics and African Americans: the IRAS family study.

Bensen JT, Hsu FC, Brown WM, Sutton BS, Norris JM, Tracy RP, Jenny NS, Saad MF, Haffner S, Bowden DW, Langefeld CD.

Hum Hered. 2004;57(3):128-37.PMID: 15297806 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study.

Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Wagenknecht LE, Bergman RN; Insulin Resistance Atherosclerosis Study Family Study.

Diabetes. 2004 Jul;53(7):1866-75.PMID: 15220212 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic and inflammation variable clusters and prediction of type 2 diabetes: factor analysis using directly measured insulin sensitivity.

Hanley AJ, Festa A, D'Agostino RB Jr, Wagenknecht LE, Savage PJ, Tracy RP, Saad MF, Haffner SM.

Diabetes. 2004 Jul;53(7):1773-81.PMID: 15220201 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin sensitivity, body fat distribution, and family diabetes history: the IRAS Family Study.

Mitchell BD, Zaccaro D, Wagenknecht LE, Scherzinger AL, Bergman RN, Haffner SM, Hokanson J, Norris JM, Rotter JI, Saad MF.

Obes Res. 2004 May;12(5):831-9.PMID: 15166304 [PubMed - indexed for MEDLINE]Related articles

Ragaglitazar improves glycemic control and lipid profile in type 2 diabetic subjects: a 12-week, double-blind, placebo-controlled dose-ranging study with an open pioglitazone arm.

Saad MF, Greco S, Osei K, Lewin AJ, Edwards C, Nunez M, Reinhardt RR; Ragaglitazar Dose-Ranging Study Group.

Diabetes Care. 2004 Jun;27(6):1324-9.PMID: 15161783 [PubMed - indexed for MEDLINE]Related articlesFree article

Differences in insulin resistance in nondiabetic subjects with isolated impaired glucose tolerance or isolated impaired fasting glucose.

Festa A, D'Agostino R Jr, Hanley AJ, Karter AJ, Saad MF, Haffner SM.

Diabetes. 2004 Jun;53(6):1549-55.PMID: 15161760 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of leptin receptor polymorphism with insulin resistance.

Chiu KC, Chu A, Chuang LM, Saad MF.

Eur J Endocrinol. 2004 May;150(5):725-9.PMID: 15132731 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance and hypertension: the Insulin Resistance Atherosclerosis study.

Saad MF, Rewers M, Selby J, Howard G, Jinagouda S, Fahmi S, Zaccaro D, Bergman RN, Savage PJ, Haffner SM.

Hypertension. 2004 Jun;43(6):1324-31. Epub 2004 May 3.PMID: 15123571 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction.

Chiu KC, Chu A, Go VL, Saad MF.

Am J Clin Nutr. 2004 May;79(5):820-5.PMID: 15113720 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of insulin sensitivity and beta-cell function indexes obtained from minimal model analysis of a meal tolerance test.

Steil GM, Hwu CM, Janowski R, Hariri F, Jinagouda S, Darwin C, Tadros S, Rebrin K, Saad MF.

Diabetes. 2004 May;53(5):1201-7.PMID: 15111487 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination therapy for type 2 diabetes: repaglinide plus rosiglitazone.

Raskin P, McGill J, Saad MF, Cappleman JM, Kaye W, Khutoryansky N, Hale PM; Repaglinide/Rosiglitazone Study Group.

Diabet Med. 2004 Apr;21(4):329-35.PMID: 15049934 [PubMed - indexed for MEDLINE]Related articles

Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study.

Langefeld CD, Wagenknecht LE, Rotter JI, Williams AH, Hokanson JE, Saad MF, Bowden DW, Haffner S, Norris JM, Rich SS, Mitchell BD; Insulin Resistance Atherosclerosis Study Family Study.

Diabetes. 2004 Apr;53(4):1170-4.PMID: 15047638 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin sensitivity, insulinemia, and coronary artery disease: the Insulin Resistance Atherosclerosis Study.

Rewers M, Zaccaro D, D'Agostino R, Haffner S, Saad MF, Selby JV, Bergman R, Savage P; Insulin Resistance Atherosclerosis Study Investigators.

Diabetes Care. 2004 Mar;27(3):781-7.PMID: 14988302 [PubMed - indexed for MEDLINE]Related articlesFree article

Modeling beta-cell insulin secretion--implications for closed-loop glucose homeostasis.

Steil GM, Rebrin K, Janowski R, Darwin C, Saad MF.

Diabetes Technol Ther. 2003;5(6):953-64.PMID: 14709197 [PubMed - indexed for MEDLINE]Related articles