PubMed

The multifaceted influence of the mucosal microflora on mucosal dendritic cell responses.

Strober W.

Immunity. 2009 Sep 18;31(3):377-88. Review.PMID: 19766081 [PubMed - indexed for MEDLINE]Related articles

The signaling function of the IL-13Ralpha2 receptor in the development of gastrointestinal fibrosis and cancer surveillance.

Strober W, Kitani A, Fichtner-Feigl S, Fuss IJ.

Curr Mol Med. 2009 Aug;9(6):740-50.PMID: 19689301 [PubMed - in process]Related articles

A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses.

Meng G, Zhang F, Fuss I, Kitani A, Strober W.

Immunity. 2009 Jun 19;30(6):860-74. Epub 2009 Jun 4.PMID: 19501001 [PubMed - indexed for MEDLINE]Related articles

The molecular basis of NOD2 susceptibility mutations in Crohn's disease.

Strober W, Kitani A, Fuss I, Asano N, Watanabe T.

Mucosal Immunol. 2008 Nov;1 Suppl 1:S5-9. Review.PMID: 19079230 [PubMed - indexed for MEDLINE]Related articles

The role of IL-13 and NK T cells in experimental and human ulcerative colitis.

Fuss IJ, Strober W.

Mucosal Immunol. 2008 Nov;1 Suppl 1:S31-3. Review.PMID: 19079225 [PubMed - indexed for MEDLINE]Related articles

Cytokines mediating the induction of chronic colitis and colitis-associated fibrosis.

Fichtner-Feigl S, Strober W, Geissler EK, Schlitt HJ.

Mucosal Immunol. 2008 Nov;1 Suppl 1:S24-7. Review.PMID: 19079223 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of intestinal inflammation. Preface.

Strober W, Zeitz M, Blumberg RS.

Mucosal Immunol. 2008 Nov;1 Suppl 1:S1-4. No abstract available. PMID: 19079219 [PubMed - indexed for MEDLINE]Related articles

Successful granulocyte-colony stimulating factor treatment of Crohn's disease is associated with the appearance of circulating interleukin-10-producing T cells and increased lamina propria plasmacytoid dendritic cells.

Mannon PJ, Leon F, Fuss IJ, Walter BA, Begnami M, Quezado M, Yang Z, Yi C, Groden C, Friend J, Hornung RL, Brown M, Gurprasad S, Kelsall B, Strober W.

Clin Exp Immunol. 2009 Mar;155(3):447-56. Epub 2008 Dec 15.PMID: 19094118 [PubMed - indexed for MEDLINE]Related articles

Vitamin A rewrites the ABCs of oral tolerance.

Strober W.

Mucosal Immunol. 2008 Mar;1(2):92-5. Epub 2008 Jan 16. Review.PMID: 19079166 [PubMed - indexed for MEDLINE]Related articles

IL-13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis.

Fichtner-Feigl S, Young CA, Kitani A, Geissler EK, Schlitt HJ, Strober W.

Gastroenterology. 2008 Dec;135(6):2003-13, 2013.e1-7. Epub 2008 Sep 11.PMID: 18938165 [PubMed - indexed for MEDLINE]Related articles

Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells.

Zhang F, Meng G, Strober W.

Nat Immunol. 2008 Nov;9(11):1297-306. Epub 2008 Oct 12. Erratum in: Nat Immunol. 2009 Feb;10(2):223. PMID: 18849990 [PubMed - indexed for MEDLINE]Related articles

Why study animal models of IBD?

Strober W.

Inflamm Bowel Dis. 2008 Oct;14 Suppl 2:S129-31. No abstract available. Erratum in: Inflamm Bowel Dis. 2009 Sep;15(9):1438-47. PMID: 18816654 [PubMed - in process]Related articlesFree article

Wright-Giemsa and nonspecific esterase staining of cells.

Strober W.

Curr Protoc Cytom. 2001 May;Appendix 3:Appendix 3D.PMID: 18770656 [PubMed - indexed for MEDLINE]Related articles

A transient breach in the epithelial barrier leads to regulatory T-cell generation and resistance to experimental colitis.

Boirivant M, Amendola A, Butera A, Sanchez M, Xu L, Marinaro M, Kitani A, Di Giacinto C, Strober W, Fuss IJ.

Gastroenterology. 2008 Nov;135(5):1612-1623.e5. Epub 2008 Aug 5.PMID: 18765239 [PubMed - indexed for MEDLINE]Related articles

T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.

Pesu M, Watford WT, Wei L, Xu L, Fuss I, Strober W, Andersson J, Shevach EM, Quezado M, Bouladoux N, Roebroek A, Belkaid Y, Creemers J, O'Shea JJ.

Nature. 2008 Sep 11;455(7210):246-50.PMID: 18701887 [PubMed - indexed for MEDLINE]Related articlesFree article

Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor-alpha 2.

Fichtner-Feigl S, Terabe M, Kitani A, Young CA, Fuss I, Geissler EK, Schlitt HJ, Berzofsky JA, Strober W.

Cancer Res. 2008 May 1;68(9):3467-75.PMID: 18451175 [PubMed - indexed for MEDLINE]Related articlesFree article

Obtaining human peripheral blood cells.

Strober W.

Curr Protoc Immunol. 2001 May;Appendix 3:Appendix 3F.PMID: 18432658 [PubMed - indexed for MEDLINE]Related articles

Wright-Giemsa and nonspecific esterase staining of cells.

Strober W.

Curr Protoc Immunol. 2001 May;Appendix 3:Appendix 3C.PMID: 18432655 [PubMed - indexed for MEDLINE]Related articles

Trypan blue exclusion test of cell viability.

Strober W.

Curr Protoc Immunol. 2001 May;Appendix 3:Appendix 3B.PMID: 18432654 [PubMed - indexed for MEDLINE]Related articles

Monitoring cell growth.

Strober W.

Curr Protoc Immunol. 2001 May;Appendix 3:Appendix 3A.PMID: 18432653 [PubMed - indexed for MEDLINE]Related articles

Laboratory safety.

Meisenhelder J, Bursik S, Lunn G, Strober W.

Curr Protoc Hum Genet. 2008 Apr;Appendix 2:Appendix 2A.PMID: 18428418 [PubMed - indexed for MEDLINE]Related articles

Notch1 signaling and regulatory T cell function.

Asano N, Watanabe T, Kitani A, Fuss IJ, Strober W.

J Immunol. 2008 Mar 1;180(5):2796-804.PMID: 18292500 [PubMed - indexed for MEDLINE]Related articlesFree article

Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.

Watanabe T, Asano N, Murray PJ, Ozato K, Tailor P, Fuss IJ, Kitani A, Strober W.

J Clin Invest. 2008 Feb;118(2):545-59.PMID: 18188453 [PubMed - indexed for MEDLINE]Related articlesFree article

NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction.

Yang Z, Fuss IJ, Watanabe T, Asano N, Davey MP, Rosenbaum JT, Strober W, Kitani A.

Gastroenterology. 2007 Nov;133(5):1510-21. Epub 2007 Jul 25.PMID: 17915219 [PubMed - indexed for MEDLINE]Related articlesFree article

The mechanism of action of probiotics.

Boirivant M, Strober W.

Curr Opin Gastroenterol. 2007 Nov;23(6):679-92. Review.PMID: 17906447 [PubMed - indexed for MEDLINE]Related articles

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta.

Xu L, Kitani A, Fuss I, Strober W.

J Immunol. 2007 Jun 1;178(11):6725-9.PMID: 17513718 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of IL-13 triggers TGF-beta1-dependent tissue fibrosis in chronic 2,4,6-trinitrobenzene sulfonic acid colitis.

Fichtner-Feigl S, Fuss IJ, Young CA, Watanabe T, Geissler EK, Schlitt HJ, Kitani A, Strober W.

J Immunol. 2007 May 1;178(9):5859-70.PMID: 17442970 [PubMed - indexed for MEDLINE]Related articlesFree article

The fundamental basis of inflammatory bowel disease.

Strober W, Fuss I, Mannon P.

J Clin Invest. 2007 Mar;117(3):514-21. Review.PMID: 17332878 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGF-beta1-mediated suppression of colitis.

Boirivant M, Pallone F, Di Giacinto C, Fina D, Monteleone I, Marinaro M, Caruso R, Colantoni A, Palmieri G, Sanchez M, Strober W, MacDonald TT, Monteleone G.

Gastroenterology. 2006 Dec;131(6):1786-98. Epub 2006 Sep 19.PMID: 17087939 [PubMed - indexed for MEDLINE]Related articles

Antibodies to complement receptor 3 treat established inflammation in murine models of colitis and a novel model of psoriasiform dermatitis.

Leon F, Contractor N, Fuss I, Marth T, Lahey E, Iwaki S, la Sala A, Hoffmann V, Strober W, Kelsall BL.

J Immunol. 2006 Nov 15;177(10):6974-82.PMID: 17082612 [PubMed - indexed for MEDLINE]Related articlesFree article

Excess IL-12 but not IL-23 accompanies the inflammatory bowel disease associated with common variable immunodeficiency.

Mannon PJ, Fuss IJ, Dill S, Friend J, Groden C, Hornung R, Yang Z, Yi C, Quezado M, Brown M, Strober W.

Gastroenterology. 2006 Sep;131(3):748-56.PMID: 16952544 [PubMed - indexed for MEDLINE]Related articles

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis.

Watanabe T, Kitani A, Murray PJ, Wakatsuki Y, Fuss IJ, Strober W.

Immunity. 2006 Sep;25(3):473-85. Epub 2006 Aug 31.PMID: 16949315 [PubMed - indexed for MEDLINE]Related articles

Immunology. Unraveling gut inflammation.

Strober W.

Science. 2006 Aug 25;313(5790):1052-4. No abstract available. PMID: 16931742 [PubMed - indexed for MEDLINE]Related articles

TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling.

Oida T, Xu L, Weiner HL, Kitani A, Strober W.

J Immunol. 2006 Aug 15;177(4):2331-9.PMID: 16887994 [PubMed - indexed for MEDLINE]Related articlesFree article

Experimental models of mucosal inflammation.

Strober W, Fuss IJ.

Adv Exp Med Biol. 2006;579:55-97. Review. No abstract available. PMID: 16620012 [PubMed - indexed for MEDLINE]Related articles

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription.

Usui T, Preiss JC, Kanno Y, Yao ZJ, Bream JH, O'Shea JJ, Strober W.

J Exp Med. 2006 Mar 20;203(3):755-66. Epub 2006 Mar 6. Erratum in: J Exp Med. 2006 Apr 17;203(4):1129. PMID: 16520391 [PubMed - indexed for MEDLINE]Related articlesFree article

Signalling pathways and molecular interactions of NOD1 and NOD2.

Strober W, Murray PJ, Kitani A, Watanabe T.

Nat Rev Immunol. 2006 Jan;6(1):9-20. Review.PMID: 16493424 [PubMed - indexed for MEDLINE]Related articles

Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody.

Fuss IJ, Becker C, Yang Z, Groden C, Hornung RL, Heller F, Neurath MF, Strober W, Mannon PJ.

Inflamm Bowel Dis. 2006 Jan;12(1):9-15.PMID: 16374252 [PubMed - indexed for MEDLINE]Related articles

Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa.

Belyakov IM, Kuznetsov VA, Kelsall B, Klinman D, Moniuszko M, Lemon M, Markham PD, Pal R, Clements JD, Lewis MG, Strober W, Franchini G, Berzofsky JA.

Blood. 2006 Apr 15;107(8):3258-64. Epub 2005 Dec 22.PMID: 16373659 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis.

Fichtner-Feigl S, Strober W, Kawakami K, Puri RK, Kitani A.

Nat Med. 2006 Jan;12(1):99-106. Epub 2005 Dec 4.PMID: 16327802 [PubMed - indexed for MEDLINE]Related articles

Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-kappa B decoy oligonucleotides.

Fichtner-Feigl S, Fuss IJ, Preiss JC, Strober W, Kitani A.

J Clin Invest. 2005 Nov;115(11):3057-71. Epub 2005 Oct 20.PMID: 16239967 [PubMed - indexed for MEDLINE]Related articlesFree article

NOD2 regulation of Toll-like receptor responses and the pathogenesis of Crohn's disease.

Watanabe T, Kitani A, Strober W.

Gut. 2005 Nov;54(11):1515-8. Review. No abstract available. PMID: 16227353 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution.

Heller F, Florian P, Bojarski C, Richter J, Christ M, Hillenbrand B, Mankertz J, Gitter AH, Bürgel N, Fromm M, Zeitz M, Fuss I, Strober W, Schulzke JD.

Gastroenterology. 2005 Aug;129(2):550-64.PMID: 16083712 [PubMed - indexed for MEDLINE]Related articles

Immunosuppressive therapy in Whipple's disease patients is associated with the appearance of gastrointestinal manifestations.

Mahnel R, Kalt A, Ring S, Stallmach A, Strober W, Marth T.

Am J Gastroenterol. 2005 May;100(5):1167-73.PMID: 15842595 [PubMed - indexed for MEDLINE]Related articles

Downstream effector functions of T-cell activation.

Strober W.

J Pediatr Gastroenterol Nutr. 2005 Apr;40 Suppl 1:S26. Review. No abstract available. PMID: 15805837 [PubMed - indexed for MEDLINE]Related articles

Probiotics ameliorate recurrent Th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells.

Di Giacinto C, Marinaro M, Sanchez M, Strober W, Boirivant M.

J Immunol. 2005 Mar 15;174(6):3237-46.PMID: 15749854 [PubMed - indexed for MEDLINE]Related articlesFree article

Natural killer T cells in mucosal homeostasis.

Kaser A, Nieuwenhuis EE, Strober W, Mayer L, Fuss I, Colgan S, Blumberg RS.

Ann N Y Acad Sci. 2004 Dec;1029:154-68. Review.PMID: 15681754 [PubMed - indexed for MEDLINE]Related articles

Insights into the mechanism of oral tolerance derived from the study of models of mucosal inflammation.

Strober W, Fuss I, Boirivant M, Kitani A.

Ann N Y Acad Sci. 2004 Dec;1029:115-31. Review.PMID: 15681751 [PubMed - indexed for MEDLINE]Related articles

Regulatory cells induced by feeding TNP-haptenated colonic protein cross-protect mice from colitis induced by an unrelated hapten.

Boirivant M, Strober W, Fuss IJ.

Inflamm Bowel Dis. 2005 Jan;11(1):48-55.PMID: 15674113 [PubMed - indexed for MEDLINE]Related articles

A major quantitative trait locus on mouse chromosome 3 is involved in disease susceptibility in different colitis models.

Borm ME, He J, Kelsall B, Peña AS, Strober W, Bouma G.

Gastroenterology. 2005 Jan;128(1):74-85.PMID: 15633125 [PubMed - indexed for MEDLINE]Related articles