PubMed

The transcription factor GATA-2 does not associate with angiographic coronary artery disease in the Ottawa Heart Genomics and Cleveland Clinic GeneBank Studies.

Dandona S, Chen L, Fan M, Alam MA, Assogba O, Belanger M, Williams K, Wells GA, Tang WH, Ellis SG, Hazen SL, McPherson R, Roberts R, Stewart AF.

Hum Genet. 2009 Nov 3. [Epub ahead of print]PMID: 19885677 [PubMed - as supplied by publisher]Related articles

Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I.

Kirk JA, Macgowan GA, Evans C, Smith SH, Warren CM, Mamidi R, Chandra M, Stewart AF, Solaro RJ, Shroff SG.

Circ Res. 2009 Dec 4;105(12):1232-9. Epub 2009 Oct 22.PMID: 19850940 [PubMed - in process]Related articles

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.

Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, Salo P, Voight BF, Burns P, Laskowski RA, Xue Y, Menzel S, Altshuler D, Bradley JR, Bumpstead S, Burnett MS, Devaney J, Döring A, Elosua R, Epstein SE, Erber W, Falchi M, Garner SF, Ghori MJ, Goodall AH, Gwilliam R, Hakonarson HH, Hall AS, Hammond N, Hengstenberg C, Illig T, König IR, Knouff CW, McPherson R, Melander O, Mooser V, Nauck M, Nieminen MS, O'Donnell CJ, Peltonen L, Potter SC, Prokisch H, Rader DJ, Rice CM, Roberts R, Salomaa V, Sambrook J, Schreiber S, Schunkert H, Schwartz SM, Serbanovic-Canic J, Sinisalo J, Siscovick DS, Stark K, Surakka I, Stephens J, Thompson JR, Völker U, Völzke H, Watkins NA, Wells GA, Wichmann HE, Van Heel DA, Tyler-Smith C, Thein SL, Kathiresan S, Perola M, Reilly MP, Stewart AF, Erdmann J, Samani NJ, Meisinger C, Greinacher A, Deloukas P, Ouwehand WH, Gieger C.

Nat Genet. 2009 Nov;41(11):1182-90. Epub 2009 Oct 11.PMID: 19820697 [PubMed - in process]Related articles

A quadraplexed real-time PCR assay for rapid detection and differentiation of the Clostridium botulinum toxin genes A, B, E and F.

Satterfield BA, Stewart AF, Lew CS, Pickett DO, Cohen MN, Moore EA, Luedtke PF, O'Neill KL, Robison RA.

J Med Microbiol. 2009 Sep 24. [Epub ahead of print]PMID: 19779029 [PubMed - as supplied by publisher]Related articles

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice.

Anastassiadis K, Fu J, Patsch C, Hu S, Weidlich S, Duerschke K, Buchholz F, Edenhofer F, Stewart AF.

Dis Model Mech. 2009 Sep-Oct;2(9-10):508-15. Epub 2009 Aug 19.PMID: 19692579 [PubMed - in process]Related articles

Patient information page from the Hormone Foundation. High blood calcium (Hypercalcemia).

Leder B, Silverberg SJ, Stewart AF.

J Clin Endocrinol Metab. 2009 Jul;94(7):2670. English, Spanish. No abstract available. PMID: 19593858 [PubMed - indexed for MEDLINE]Related articles

Functional analysis of the chromosome 9p21.3 coronary artery disease risk locus.

Jarinova O, Stewart AF, Roberts R, Wells G, Lau P, Naing T, Buerki C, McLean BW, Cook RC, Parker JS, McPherson R.

Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1671-7. Epub 2009 Jul 10.PMID: 19592466 [PubMed - indexed for MEDLINE]Related articles

Conformational adaptability of Redbeta during DNA annealing and implications for its structural relationship with Rad52.

Erler A, Wegmann S, Elie-Caille C, Bradshaw CR, Maresca M, Seidel R, Habermann B, Muller DJ, Stewart AF.

J Mol Biol. 2009 Aug 21;391(3):586-98. Epub 2009 Jun 13.PMID: 19527729 [PubMed - indexed for MEDLINE]Related articles

The retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells.

Harb G, Vasavada RC, Cobrinik D, Stewart AF.

Diabetes. 2009 Aug;58(8):1852-62. Epub 2009 Jun 9. Erratum in: Diabetes. 2009 Oct;58(10):2425. PMID: 19509021 [PubMed - indexed for MEDLINE]Related articlesFree article

Doxycycline-dependent photoactivated gene expression in eukaryotic systems.

Cambridge SB, Geissler D, Calegari F, Anastassiadis K, Hasan MT, Stewart AF, Huttner WB, Hagen V, Bonhoeffer T.

Nat Methods. 2009 Jul;6(7):527-31. Epub 2009 Jun 7.PMID: 19503080 [PubMed - indexed for MEDLINE]Related articles

Message from the editor: on humility.

Hauser SL, Stewart AF, Johnston SC.

Ann Neurol. 2009 May;65(5):A7-8. No abstract available. PMID: 19479725 [PubMed - indexed for MEDLINE]Related articles

Lack of association of chromosome 9p21.3 genotype with cardiovascular function in persons with stable coronary artery disease: The heart and soul study.

Dandona S, Stewart AF.

Atherosclerosis. 2009 Aug;205(2):367; author reply 368. Epub 2009 Apr 5. No abstract available. PMID: 19409564 [PubMed - in process]Related articles

Identification of protein/DNA contacts with dimethyl sulfate: methylation protection and methylation interference.

Shaw PE, Stewart AF.

Methods Mol Biol. 2009;543:97-104.PMID: 19378162 [PubMed - indexed for MEDLINE]Related articles

Kinesin family member 6 variant Trp719Arg does not associate with angiographically defined coronary artery disease in the Ottawa Heart Genomics Study.

Stewart AF, Dandona S, Chen L, Assogba O, Belanger M, Ewart G, LaRose R, Doelle H, Williams K, Wells GA, McPherson R, Roberts R.

J Am Coll Cardiol. 2009 Apr 21;53(16):1471-2. No abstract available. PMID: 19371834 [PubMed - indexed for MEDLINE]Related articles

The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis.

Glaser S, Lubitz S, Loveland KL, Ohbo K, Robb L, Schwenk F, Seibler J, Roellig D, Kranz A, Anastassiadis K, Stewart AF.

Epigenetics Chromatin. 2009 Apr 6;2(1):5.PMID: 19348672 [PubMed - in process]Related articlesFree article

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.

Ding L, Paszkowski-Rogacz M, Nitzsche A, Slabicki MM, Heninger AK, de Vries I, Kittler R, Junqueira M, Shevchenko A, Schulz H, Hubner N, Doss MX, Sachinidis A, Hescheler J, Iacone R, Anastassiadis K, Stewart AF, Pisabarro MT, Caldarelli A, Poser I, Theis M, Buchholz F.

Cell Stem Cell. 2009 May 8;4(5):403-15. Epub 2009 Apr 2.PMID: 19345177 [PubMed - indexed for MEDLINE]Related articles

Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet-induced weight loss.

Teng AC, Adamo K, Tesson F, Stewart AF.

FASEB J. 2009 Jun;23(6):1705-9. Epub 2009 Feb 13.PMID: 19218499 [PubMed - indexed for MEDLINE]Related articles

Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement.

Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart AF, Birkett N.

J Clin Epidemiol. 2009 Jun;62(6):597-608.e4. Epub 2009 Feb 12.PMID: 19217256 [PubMed - indexed for MEDLINE]Related articles

Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo.

Fiaschi-Taesch N, Bigatel TA, Sicari B, Takane KK, Salim F, Velazquez-Garcia S, Harb G, Selk K, Cozar-Castellano I, Stewart AF.

Diabetes. 2009 Apr;58(4):882-93. Epub 2009 Jan 9.PMID: 19136653 [PubMed - indexed for MEDLINE]Related articlesFree article

Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.

Shevchenko A, Roguev A, Schaft D, Buchanan L, Habermann B, Sakalar C, Thomas H, Krogan NJ, Shevchenko A, Stewart AF.

Genome Biol. 2008;9(11):R167. Epub 2008 Nov 28.PMID: 19040720 [PubMed - indexed for MEDLINE]Related articlesFree article

From genes to regenerative medicine: approaches in development.

Ruel M, Stewart AF, Suuronen EJ.

Circ Res. 2008 Nov 7;103(10):1050-2. No abstract available. PMID: 18988900 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutant parathyroid hormone-related protein, devoid of the nuclear localization signal, markedly inhibits arterial smooth muscle cell cycle and neointima formation by coordinate up-regulation of p15Ink4b and p27kip1.

Fiaschi-Taesch N, Sicari B, Ubriani K, Cozar-Castellano I, Takane KK, Stewart AF.

Endocrinology. 2009 Mar;150(3):1429-39. Epub 2008 Oct 9.PMID: 18845646 [PubMed - indexed for MEDLINE]Related articles

Hepatocyte growth factor enhances engraftment and function of nonhuman primate islets.

Fiaschi-Taesch NM, Berman DM, Sicari BM, Takane KK, Garcia-Ocaña A, Ricordi C, Kenyon NS, Stewart AF.

Diabetes. 2008 Oct;57(10):2745-54.PMID: 18820214 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoparathyroidism: is it time for replacement therapy?

Horwitz MJ, Stewart AF.

J Clin Endocrinol Metab. 2008 Sep;93(9):3307-9. No abstract available. PMID: 18772463 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition.

Fu J, Wenzel SC, Perlova O, Wang J, Gross F, Tang Z, Yin Y, Stewart AF, Müller R, Zhang Y.

Nucleic Acids Res. 2008 Oct;36(17):e113. Epub 2008 Aug 13.PMID: 18701643 [PubMed - indexed for MEDLINE]Related articlesFree article

Lessons from the first comprehensive molecular characterization of cell cycle control in rodent insulinoma cell lines.

Cozar-Castellano I, Harb G, Selk K, Takane K, Vasavada R, Sicari B, Law B, Zhang P, Scott DK, Fiaschi-Taesch N, Stewart AF.

Diabetes. 2008 Nov;57(11):3056-68. Epub 2008 Jul 23.PMID: 18650366 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte Growth Factor (HGF) Enhances Engraftment and Function of Non-Human Primate Islets.

Fiaschi-Taesch NM, Berman DM, Sicari BM, Takane KK, Garcia-Ocaña A, Ricordi C, Kenyon NS, Stewart AF.

Diabetes. 2008 Jul 15. [Epub ahead of print]PMID: 18633102 [PubMed - as supplied by publisher]Related articles

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.

Poser I, Sarov M, Hutchins JR, Hériché JK, Toyoda Y, Pozniakovsky A, Weigl D, Nitzsche A, Hegemann B, Bird AW, Pelletier L, Kittler R, Hua S, Naumann R, Augsburg M, Sykora MM, Hofemeister H, Zhang Y, Nasmyth K, White KP, Dietzel S, Mechtler K, Durbin R, Stewart AF, Peters JM, Buchholz F, Hyman AA.

Nat Methods. 2008 May;5(5):409-15. Epub 2008 Apr 6. Erratum in: Nat Methods. 2008 Aug;5(8):748. PMID: 18391959 [PubMed - indexed for MEDLINE]Related articles

Bacterial artificial chromosome transgenesis through pronuclear injection of fertilized mouse oocytes.

Vintersten K, Testa G, Naumann R, Anastassiadis K, Stewart AF.

Methods Mol Biol. 2008;415:83-100.PMID: 18370149 [PubMed - indexed for MEDLINE]Related articles

Mouse mammary tumor virus (MMTV)-like DNA sequences in the breast tumors of father, mother, and daughter.

Etkind PR, Stewart AF, Wiernik PH.

Infect Agent Cancer. 2008 Feb 28;3:2.PMID: 18307792 [PubMed - in process]Related articlesFree article

The United States endocrinology workforce: a supply-demand mismatch.

Stewart AF.

J Clin Endocrinol Metab. 2008 Apr;93(4):1164-6. Epub 2008 Jan 29. No abstract available. PMID: 18230655 [PubMed - indexed for MEDLINE]Related articlesFree article

Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic.

Augui S, Filion GJ, Huart S, Nora E, Guggiari M, Maresca M, Stewart AF, Heard E.

Science. 2007 Dec 7;318(5856):1632-6.PMID: 18063799 [PubMed - indexed for MEDLINE]Related articlesFree article

Identifying genes for coronary artery disease: An idea whose time has come.

Roberts R, Stewart AF, Wells GA, Williams KA, Kavaslar N, McPherson R.

Can J Cardiol. 2007 Aug;23 Suppl A:7A-15A. Review.PMID: 17668082 [PubMed - indexed for MEDLINE]Related articles

Improving islet transplantation by gene delivery of hepatocyte growth factor (HGF) and its downstream target, protein kinase B (PKB)/Akt.

Fiaschi-Taesch N, Stewart AF, Garcia-Ocaña A.

Cell Biochem Biophys. 2007;48(2-3):191-9. Review.PMID: 17709889 [PubMed - indexed for MEDLINE]Related articles

Characterization of cardiac gene promoter activity: reporter constructs and heterologous promoter studies.

Chen HH, Stewart AF.

Methods Mol Biol. 2007;366:217-25.PMID: 17568127 [PubMed - indexed for MEDLINE]Related articles

Extracellular ATP-dependent upregulation of the transcription cofactor LMO4 promotes neuron survival from hypoxia.

Chen HH, Schock SC, Xu J, Safarpour F, Thompson CS, Stewart AF.

Exp Cell Res. 2007 Aug 15;313(14):3106-16. Epub 2007 May 3.PMID: 17524392 [PubMed - indexed for MEDLINE]Related articles

Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2.

Lubitz S, Glaser S, Schaft J, Stewart AF, Anastassiadis K.

Mol Biol Cell. 2007 Jun;18(6):2356-66. Epub 2007 Apr 11.PMID: 17429066 [PubMed - indexed for MEDLINE]Related articlesFree article

LMO4 mRNA stability is regulated by extracellular ATP in F11 cells.

Chen HH, Xu J, Safarpour F, Stewart AF.

Biochem Biophys Res Commun. 2007 May 25;357(1):56-61. Epub 2007 Mar 28.PMID: 17418808 [PubMed - indexed for MEDLINE]Related articles

Tissue-specific deletion of the retinoblastoma protein in the pancreatic beta-cell has limited effects on beta-cell replication, mass, and function.

Vasavada RC, Cozar-Castellano I, Sipula D, Stewart AF.

Diabetes. 2007 Jan;56(1):57-64.PMID: 17192465 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic engineering of Pseudomonas putida for methylmalonyl-CoA biosynthesis to enable complex heterologous secondary metabolite formation.

Gross F, Ring MW, Perlova O, Fu J, Schneider S, Gerth K, Kuhlmann S, Stewart AF, Zhang Y, Müller R.

Chem Biol. 2006 Dec;13(12):1253-64.PMID: 17185221 [PubMed - indexed for MEDLINE]Related articles

Engineering embryonic stem cells with recombinase systems.

Schnütgen F, Stewart AF, von Melchner H, Anastassiadis K.

Methods Enzymol. 2006;420:100-36.PMID: 17161696 [PubMed - indexed for MEDLINE]Related articles

The cell cycle inhibitory protein p21cip is not essential for maintaining beta-cell cycle arrest or beta-cell function in vivo.

Cozar-Castellano I, Haught M, Stewart AF.

Diabetes. 2006 Dec;55(12):3271-8.PMID: 17130470 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular mechanism through which parathyroid hormone-related protein induces proliferation in arterial smooth muscle cells: definition of an arterial smooth muscle PTHrP/p27kip1 pathway.

Fiaschi-Taesch N, Sicari BM, Ubriani K, Bigatel T, Takane KK, Cozar-Castellano I, Bisello A, Law B, Stewart AF.

Circ Res. 2006 Oct 27;99(9):933-42. Epub 2006 Oct 5.PMID: 17023675 [PubMed - indexed for MEDLINE]Related articlesFree article

Reconstitution of the myxothiazol biosynthetic gene cluster by Red/ET recombination and heterologous expression in Myxococcus xanthus.

Perlova O, Fu J, Kuhlmann S, Krug D, Stewart AF, Zhang Y, Müller R.

Appl Environ Microbiol. 2006 Dec;72(12):7485-94. Epub 2006 Sep 22.PMID: 16997979 [PubMed - indexed for MEDLINE]Related articlesFree article

Surveillance for early detection of aggressive parathyroid disease: carcinoma and atypical adenoma in familial isolated hyperparathyroidism associated with a germline HRPT2 mutation.

Kelly TG, Shattuck TM, Reyes-Mugica M, Stewart AF, Simonds WF, Udelsman R, Arnold A, Carpenter TO.

J Bone Miner Res. 2006 Oct;21(10):1666-71.PMID: 16995822 [PubMed - indexed for MEDLINE]Related articles

A recombineering pipeline for functional genomics applied to Caenorhabditis elegans.

Sarov M, Schneider S, Pozniakovski A, Roguev A, Ernst S, Zhang Y, Hyman AA, Stewart AF.

Nat Methods. 2006 Oct;3(10):839-44.PMID: 16990816 [PubMed - indexed for MEDLINE]Related articles

Recombineering reagents for improved inducible expression and selection marker re-use in Schizosaccharomyces pombe.

Erler A, Maresca M, Fu J, Stewart AF.

Yeast. 2006 Aug;23(11):813-23.PMID: 16921581 [PubMed - indexed for MEDLINE]Related articles

Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation.

Dehé PM, Dichtl B, Schaft D, Roguev A, Pamblanco M, Lebrun R, Rodríguez-Gil A, Mkandawire M, Landsberg K, Shevchenko A, Shevchenko A, Rosaleny LE, Tordera V, Chávez S, Stewart AF, Géli V.

J Biol Chem. 2006 Nov 17;281(46):35404-12. Epub 2006 Aug 18.PMID: 16921172 [PubMed - indexed for MEDLINE]Related articlesFree article

Personalized genomic medicine: a future prerequisite for the prevention of coronary artery disease.

Roberts R, Stewart AF.

Am Heart Hosp J. 2006 Summer;4(3):222-7. Review.PMID: 16894262 [PubMed - indexed for MEDLINE]Related articles

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation.

Gollob MH, Jones DL, Krahn AD, Danis L, Gong XQ, Shao Q, Liu X, Veinot JP, Tang AS, Stewart AF, Tesson F, Klein GJ, Yee R, Skanes AC, Guiraudon GM, Ebihara L, Bai D.

N Engl J Med. 2006 Jun 22;354(25):2677-88.PMID: 16790700 [PubMed - indexed for MEDLINE]Related articlesFree article