PubMed

Randomized double-blind phase II trial comparing gemcitabine plus LY293111 versus gemcitabine plus placebo in advanced adenocarcinoma of the pancreas.

Saif MW, Oettle H, Vervenne WL, Thomas JP, Spitzer G, Visseren-Grul C, Enas N, Richards DA.

Cancer J. 2009 Jul-Aug;15(4):339-43.PMID: 19672152 [PubMed - in process]Related articles

How to optimize shape-based virtual screening: choosing the right query and including chemical information.

Kirchmair J, Distinto S, Markt P, Schuster D, Spitzer GM, Liedl KR, Wolber G.

J Chem Inf Model. 2009 Mar;49(3):678-92.PMID: 19434901 [PubMed - indexed for MEDLINE]Related articles

Hydrogen-bonding patterns of minor groove-binder-DNA complexes reveal criteria for discovery of new scaffolds.

Spitzer GM, Wellenzohn B, Markt P, Kirchmair J, Langer T, Liedl KR.

J Chem Inf Model. 2009 Apr;49(4):1063-9.PMID: 19275189 [PubMed - indexed for MEDLINE]Related articles

How To Optimize Shape-Based Virtual Screening: Choosing the Right Query and Including Chemical Information.

Kirchmair J, Distinto S, Markt P, Schuster D, Spitzer GM, Liedl KR, Wolber G.

J Chem Inf Model. 2009 Feb 18. [Epub ahead of print]PMID: 19226159 [PubMed - as supplied by publisher]Related articles

Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow.

Markt P, Feldmann C, Rollinger JM, Raduner S, Schuster D, Kirchmair J, Distinto S, Spitzer GM, Wolber G, Laggner C, Altmann KH, Langer T, Gertsch J.

J Med Chem. 2009 Jan 22;52(2):369-78.PMID: 19143566 [PubMed - indexed for MEDLINE]Related articles

Sequence-specific positions of water molecules at the interface between DNA and minor groove binders.

Spitzer GM, Fuchs JE, Markt P, Kirchmair J, Wellenzohn B, Langer T, Liedl KR.

Chemphyschem. 2008 Dec 22;9(18):2766-71.PMID: 19025733 [PubMed - indexed for MEDLINE]Related articles

The Protein Data Bank (PDB), its related services and software tools as key components for in silico guided drug discovery.

Kirchmair J, Markt P, Distinto S, Schuster D, Spitzer GM, Liedl KR, Langer T, Wolber G.

J Med Chem. 2008 Nov 27;51(22):7021-40. No abstract available. PMID: 18975926 [PubMed - indexed for MEDLINE]Related articles

Discovery of novel PPAR ligands by a virtual screening approach based on pharmacophore modeling, 3D shape, and electrostatic similarity screening.

Markt P, Petersen RK, Flindt EN, Kristiansen K, Kirchmair J, Spitzer G, Distinto S, Schuster D, Wolber G, Laggner C, Langer T.

J Med Chem. 2008 Oct 23;51(20):6303-17. Epub 2008 Sep 27.PMID: 18821746 [PubMed - indexed for MEDLINE]Related articles

Enhancing drug discovery through in silico screening: strategies to increase true positives retrieval rates.

Kirchmair J, Distinto S, Schuster D, Spitzer G, Langer T, Wolber G.

Curr Med Chem. 2008;15(20):2040-53. Review.PMID: 18691055 [PubMed - indexed for MEDLINE]Related articles

Discovery of novel cathepsin S inhibitors by pharmacophore-based virtual high-throughput screening.

Markt P, McGoohan C, Walker B, Kirchmair J, Feldmann C, De Martino G, Spitzer G, Distinto S, Schuster D, Wolber G, Laggner C, Langer T.

J Chem Inf Model. 2008 Aug;48(8):1693-705. Epub 2008 Jul 19.PMID: 18637674 [PubMed - indexed for MEDLINE]Related articles

DNA minor groove pharmacophores describing sequence specific properties.

Spitzer GM, Wellenzohn B, Laggner C, Langer T, Liedl KR.

J Chem Inf Model. 2007 Jul-Aug;47(4):1580-9. Epub 2007 May 23.PMID: 17518460 [PubMed - indexed for MEDLINE]Related articles

Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates.

Perera TD, Coplan JD, Lisanby SH, Lipira CM, Arif M, Carpio C, Spitzer G, Santarelli L, Scharf B, Hen R, Rosoklija G, Sackeim HA, Dwork AJ.

J Neurosci. 2007 May 2;27(18):4894-901.PMID: 17475797 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma cell disorders: myeloma and related conditions. Diagnosis and management.

Spitzer G.

J S C Med Assoc. 2003 Apr;99(4):88-93. Review. No abstract available. PMID: 12762155 [PubMed - indexed for MEDLINE]Related articles

High-dose versus standard chemotherapy in metastatic breast cancer: comparison of Cancer and Leukemia Group B trials with data from the Autologous Blood and Marrow Transplant Registry.

Berry DA, Broadwater G, Klein JP, Antman K, Aisner J, Bitran J, Costanza M, Freytes CO, Stadtmauer E, Gale RP, Henderson IC, Lazarus HM, McCarthy PL Jr, Norton L, Parnes H, Pecora A, Perry MC, Rowlings P, Spitzer G, Horowitz MM.

J Clin Oncol. 2002 Feb 1;20(3):743-50.PMID: 11821456 [PubMed - indexed for MEDLINE]Related articles

Delphi-panel analysis of appropriateness of high-dose chemotherapy and blood cell or bone marrow autotransplants in women with breast cancer.

Gale RP, Park RE, Dubois R, Bitran JD, Buzdar A, Hortobagyi G, Jones SE, Lazar GS, Spitzer G, Swain SM, Vaughn CB, Vogel CE, Martino S.

Clin Transplant. 2000 Feb;14(1):32-41.PMID: 10693633 [PubMed - indexed for MEDLINE]Related articles

Factors correlated with progression-free survival after high-dose chemotherapy and hematopoietic stem cell transplantation for metastatic breast cancer.

Rowlings PA, Williams SF, Antman KH, Fields KK, Fay JW, Reed E, Pelz CJ, Klein JP, Sobocinski KA, Kennedy MJ, Freytes CO, McCarthy PL Jr, Herzig RH, Stadtmauer EA, Lazarus HM, Pecora AL, Bitran JD, Wolff SN, Gale RP, Armitage JO, Vaughan WP, Spitzer G, Horowitz MM.

JAMA. 1999 Oct 13;282(14):1335-43.PMID: 10527180 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of allogeneic peripheral stem cell transplantation in a patient with job syndrome of hyperimmunoglobulinemia E and recurrent infections.

Nester TA, Wagnon AH, Reilly WF, Spitzer G, Kjeldsberg CR, Hill HR.

Am J Med. 1998 Aug;105(2):162-4. No abstract available. PMID: 9727824 [PubMed - indexed for MEDLINE]Related articles

Hydroxyethylstarch sedimentation by gravity ex vivo for red cell reduction of granulocyte apheresis components.

Adkins D, Johnston M, Walsh J, Spitzer G, Goodnough T.

J Clin Apher. 1998;13(2):56-61.PMID: 9704606 [PubMed - indexed for MEDLINE]Related articles

Autologous CD34-selected blood progenitor cell transplants for patients with advanced multiple myeloma.

Schiller G, Vescio R, Freytes C, Spitzer G, Lee M, Wu CH, Cao J, Lee JC, Lichtenstein A, Lill M, Berenson R, Berenson J.

Bone Marrow Transplant. 1998 Jan;21(2):141-5.PMID: 9489630 [PubMed - indexed for MEDLINE]Related articlesFree article

Randomized comparison of G-CSF + GM-CSF vs G-CSF alone for mobilization of peripheral blood stem cells: effects on hematopoietic recovery after high-dose chemotherapy.

Spitzer G, Adkins D, Mathews M, Velasquez W, Bowers C, Dunphy F, Kronmueller N, Niemeyer R, McIntyre W, Petruska P.

Bone Marrow Transplant. 1997 Dec;20(11):921-30.PMID: 9422470 [PubMed - indexed for MEDLINE]Related articlesFree article

A phase II study of repetitive cycles of dose-intense carboplatin plus paclitaxel chemotherapy and peripheral blood stem cells in metastatic breast cancer.

Ford C, Spitzer G, Reilly W, Adkins D.

Semin Oncol. 1997 Oct;24(5 Suppl 17):S17-81-S17-86.PMID: 9374101 [PubMed - indexed for MEDLINE]Related articles

Transfusions of granulocyte-colony-stimulating factor-mobilized granulocyte components to allogeneic transplant recipients: analysis of kinetics and factors determining posttransfusion neutrophil and platelet counts.

Adkins D, Spitzer G, Johnston M, Velasquez W, Dunphy F, Petruska P.

Transfusion. 1997 Jul;37(7):737-48.PMID: 9225939 [PubMed - indexed for MEDLINE]Related articles

High-dose chemotherapy with autologous hematopoietic stem-cell support for breast cancer in North America.

Antman KH, Rowlings PA, Vaughan WP, Pelz CJ, Fay JW, Fields KK, Freytes CO, Gale RP, Hillner BE, Holland HK, Kennedy MJ, Klein JP, Lazarus HM, McCarthy PL Jr, Saez R, Spitzer G, Stadtmauer EA, Williams SF, Wolff S, Sobocinski KA, Armitage JO, Horowitz MM.

J Clin Oncol. 1997 May;15(5):1870-9.PMID: 9164197 [PubMed - indexed for MEDLINE]Related articles

Indium-labeled white blood cells apheresed from donors receiving G-CSF localize to sites of inflammation when infused into allogeneic bone marrow transplant recipients.

Adkins D, Goodgold H, Hendershott L, Johnston M, Cravens D, Spitzer G.

Bone Marrow Transplant. 1997 Apr;19(8):809-12.PMID: 9134173 [PubMed - indexed for MEDLINE]Related articlesFree article

Antifungal effects of yeast-derived rhu-GM-CSF in patients receiving high-dose chemotherapy given with or without autologous stem cell transplantation: a retrospective analysis.

Peters BG, Adkins DR, Harrison BR, Velasquez WS, Dunphy FR, Petruska PJ, Bowers CE, Niemeyer R, McIntyre W, Vrahnos D, Auberry SE, Spitzer G.

Bone Marrow Transplant. 1996 Jul;18(1):93-102. Review.PMID: 8832001 [PubMed - indexed for MEDLINE]Related articles

Transplantation of CD34+ peripheral blood progenitor cells after high-dose chemotherapy for patients with advanced multiple myeloma.

Schiller G, Vescio R, Freytes C, Spitzer G, Sahebi F, Lee M, Wu CH, Cao J, Lee JC, Hong CH, et al.

Blood. 1995 Jul 1;86(1):390-7.PMID: 7540888 [PubMed - indexed for MEDLINE]Related articlesFree article

Allogeneic bone marrow transplantation for leukemia following piperazinedione and fractionated total body irradiation.

Dimopoulos MA, Yau JC, Huan SD, Jagannath S, Spitzer G, Spinolo JA, Zagars GK, LeMaistre CF, Dicke KA, Zander AR.

Am J Hematol. 1994 Jun;46(2):82-6.PMID: 8172200 [PubMed - indexed for MEDLINE]Related articles

Factors predicting long-term survival for metastatic breast cancer patients treated with high-dose chemotherapy and bone marrow support.

Dunphy FR, Spitzer G, Fornoff JE, Yau JC, Huan SD, Dicke KA, Buzdar AU, Hortobagyi GN.

Cancer. 1994 Apr 15;73(8):2157-67. Erratum in: Cancer 1994 Jul 15;74(2):773. PMID: 8156520 [PubMed - indexed for MEDLINE]Related articles

Randomized study of growth factors post-peripheral-blood stem-cell transplant: neutrophil recovery is improved with modest clinical benefit.

Spitzer G, Adkins DR, Spencer V, Dunphy FR, Petruska PJ, Velasquez WS, Bowers CE, Kronmueller N, Niemeyer R, McIntyre W.

J Clin Oncol. 1994 Apr;12(4):661-70.PMID: 7512124 [PubMed - indexed for MEDLINE]Related articles

High-dose therapy with stem cell support in solid tumors.

Spitzer G, Dunphy FR, Bowers CE, Adkins DR.

Med Oncol. 1994;11(2):53-62. Review.PMID: 7850264 [PubMed - indexed for MEDLINE]Related articles

Irreversible, severe congestive cardiomyopathy occurring in association with interferon alpha therapy.

Zimmerman S, Adkins D, Graham M, Petruska P, Bowers C, Vrahnos D, Spitzer G.

Cancer Biother. 1994 Winter;9(4):291-9.PMID: 7719376 [PubMed - indexed for MEDLINE]Related articles

Persistent problems of neutropenia and thrombocytopenia with peripheral blood stem cell transplantation.

Spitzer G, Adkins DR.

J Hematother. 1994 Fall;3(3):193-8. Review.PMID: 7530134 [PubMed - indexed for MEDLINE]Related articles

Dose escalation of mitoxantrone given with thiotepa and autologous bone marrow transplantation for metastatic breast cancer.

Bowers C, Adkins D, Dunphy F, Harrison B, LeMaistre CF, Spitzer G.

Bone Marrow Transplant. 1993 Nov;12(5):525-30.PMID: 8298564 [PubMed - indexed for MEDLINE]Related articles

High dose chemotherapy followed by autologous hematopoietic rescue in Hodgkin's disease: long-term follow-up in 128 patients.

Bierman PJ, Bagin RG, Jagannath S, Vose JM, Spitzer G, Kessinger A, Dicke KA, Armitage JO.

Ann Oncol. 1993 Nov;4(9):767-73.PMID: 8280658 [PubMed - indexed for MEDLINE]Related articles

Cisplatin-CBV with autologous bone marrow transplantation for relapsed Hodgkin's disease.

Spinolo JA, Jagannath S, Velásquez W, Spitzer G, Cabanillas F, Hagemeister F, Horwitz LJ, Dicke KA.

Leuk Lymphoma. 1993 Jan;9(1-2):71-7.PMID: 8477204 [PubMed - indexed for MEDLINE]Related articles

Design of preparative regimens for stem cell transplantation in breast cancer.

Spitzer G, Adkins D, Dunphy F, Petruska P, Spencer V, Velasquez W.

Breast Cancer Res Treat. 1993;26 Suppl:S3-9. Review.PMID: 8400330 [PubMed - indexed for MEDLINE]Related articles

Tandem transplants in solid tumors: marrow versus peripheral stem cell transplant: peripheral blood cells as now practiced are not the whole answer.

Spitzer G, Dunphy FR 2nd, Petruska PJ, Velasquez WS, Adkins DR.

J Hematother. 1993 Fall;2(3):363-5.PMID: 7921997 [PubMed - indexed for MEDLINE]Related articles

Allogeneic bone marrow transplantation for hematological malignancies following etoposide, cyclophosphamide, and fractionated total body irradiation.

Yau JC, LeMaistre CF, Andersson BS, Huan SD, Wallerstein RO, Woo SY, Spitzer G, Spinolo JA, Spencer V, Brunner LJ, et al.

Am J Hematol. 1992 Sep;41(1):40-4.PMID: 1503097 [PubMed - indexed for MEDLINE]Related articles

Influence of mobilized peripheral blood cells on the hematopoietic recovery by autologous marrow and recombinant human granulocyte-macrophage colony-stimulating factor after high-dose cyclophosphamide, etoposide, and cisplatin.

Huan SD, Hester J, Spitzer G, Yau JC, Dunphy FR, Wallerstein RO, Dicke K, Spencer V, LeMaistre CF, Andersson BS, et al.

Blood. 1992 Jun 15;79(12):3388-93.PMID: 1596578 [PubMed - indexed for MEDLINE]Related articlesFree article

Autologous bone marrow transplantation in solid tumors.

Spitzer G, Velasquez W, Dunphy FR, Spencer V.

Curr Opin Oncol. 1992 Apr;4(2):272-8. Review.PMID: 1317217 [PubMed - indexed for MEDLINE]Related articles

Polyclonal hematopoiesis in interferon-induced cytogenetic remissions of chronic myelogenous leukemia.

Claxton D, Deisseroth A, Talpaz M, Reading C, Kantarjian H, Trujillo J, Stass S, Gooch G, Spitzer G.

Blood. 1992 Feb 15;79(4):997-1002.PMID: 1371081 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of very-high-dose chemotherapy with autologous bone marrow transplantation in treatment of breast cancer.

Dunphy FR, Spitzer G.

J Natl Cancer Inst. 1992 Jan 15;84(2):128-9. No abstract available. PMID: 1735880 [PubMed - indexed for MEDLINE]Related articles

Second bone marrow transplants for relapsed leukemia.

Spinolo JA, Yau JC, Dicke KA, Scott E, Jagannath S, Horwitz LJ, Spitzer G, Zander AR.

Cancer. 1992 Jan 15;69(2):405-9.PMID: 1728368 [PubMed - indexed for MEDLINE]Related articles

An effective acute graft-vs.-host disease prophylaxis with minidose methotrexate, cyclosporine, and single-dose methylprednisolone.

Yau JC, Dimopoulos MA, Huan SD, Spencer V, Woo SY, Spitzer G, Brunner LJ, Wallerstein RO, Deisseroth AB, Andersson BS, et al.

Am J Hematol. 1991 Dec;38(4):288-92.PMID: 1746537 [PubMed - indexed for MEDLINE]Related articles

Prophylaxis of cytomegalovirus infection with ganciclovir in allogeneic marrow transplantation.

Yau JC, Dimopoulos MA, Huan SD, Tarrand JJ, Spencer V, Spitzer G, Meneghetti CM, Wallerstein RO, Andersson BS, LeMaistre CF.

Eur J Haematol. 1991 Nov;47(5):371-6.PMID: 1662140 [PubMed - indexed for MEDLINE]Related articles

Intensive combination chemotherapy and autologous bone marrow transplantation leads to the reappearance of Philadelphia chromosome-negative cells in chronic myelogenous leukemia.

Kantarjian HM, Talpaz M, LeMaistre CF, Spinolo J, Spitzer G, Yau J, Dicke K, Jagannath S, Deisseroth AB.

Cancer. 1991 Jun 15;67(12):2959-65.PMID: 1675151 [PubMed - indexed for MEDLINE]Related articles

Autotransplantation in solid tumors.

Spitzer G.

Blood Rev. 1991 Jun;5(2):105-11. Review.PMID: 1912755 [PubMed - indexed for MEDLINE]Related articles

Detection of micrometastatic tumor cells in bone marrow of breast carcinoma patients.

Singletary SE, Larry L, Tucker SL, Spitzer G.

J Surg Oncol. 1991 May;47(1):32-6.PMID: 2023419 [PubMed - indexed for MEDLINE]Related articles

Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma.

Berenson RJ, Bensinger WI, Hill RS, Andrews RG, Garcia-Lopez J, Kalamasz DF, Still BJ, Spitzer G, Buckner CD, Bernstein ID, et al.

Blood. 1991 Apr 15;77(8):1717-22.PMID: 1707696 [PubMed - indexed for MEDLINE]Related articlesFree article

Autologous bone marrow transplantation in solid tumors.

Spitzer G.

Curr Opin Oncol. 1991 Apr;3(2):238-44. Review.PMID: 2069988 [PubMed - indexed for MEDLINE]Related articles