PubMed

Impaired platelet adhesion to lysed fibrin, whereas neutrophil adhesion remains intact under conditions of flow.

Remijn JA, Da Costa Martins P, Ijsseldijk MJ, Sixma JJ, de Groot PG, Zwaginga JJ.

Blood Coagul Fibrinolysis. 2006 Jul;17(5):421-4.PMID: 16788321 [PubMed - indexed for MEDLINE]Related articles

The role of collagen in thrombosis and hemostasis.

Farndale RW, Sixma JJ, Barnes MJ, de Groot PG.

J Thromb Haemost. 2004 Apr;2(4):561-73. Review. No abstract available. PMID: 15102010 [PubMed - indexed for MEDLINE]Related articles

Thrombospondin-1 mediates platelet adhesion at high shear via glycoprotein Ib (GPIb): an alternative/backup mechanism to von Willebrand factor.

Jurk K, Clemetson KJ, de Groot PG, Brodde MF, Steiner M, Savion N, Varon D, Sixma JJ, Van Aken H, Kehrel BE.

FASEB J. 2003 Aug;17(11):1490-2. Epub 2003 Jun 17.PMID: 12824298 [PubMed - indexed for MEDLINE]Related articlesFree article

Thrombopoietin increases platelet adhesion under flow and decreases rolling.

Van Os E, Wu YP, Pouwels JG, Ijsseldijk MJ, Sixma JJ, Akkerman JW, De Groot PG, Van Willigen G.

Br J Haematol. 2003 May;121(3):482-90.PMID: 12716373 [PubMed - indexed for MEDLINE]Related articles

Mapping the collagen-binding site in the von Willebrand factor-A3 domain.

Romijn RA, Westein E, Bouma B, Schiphorst ME, Sixma JJ, Lenting PJ, Huizinga EG.

J Biol Chem. 2003 Apr 25;278(17):15035-9. Epub 2003 Feb 11.PMID: 12582178 [PubMed - indexed for MEDLINE]Related articlesFree article

Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.

Huizinga EG, Tsuji S, Romijn RA, Schiphorst ME, de Groot PG, Sixma JJ, Gros P.

Science. 2002 Aug 16;297(5584):1176-9.PMID: 12183630 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced platelet adhesion in flowing blood to fibrinogen by alterations in segment gamma316-322, part of the fibrin-specific region.

Remijn JA, IJsseldijk MJ, van Hemel BM, Galanakis DK, Hogan KA, Lounes KC, Lord ST, Sixma JJ, de Groot PG.

Br J Haematol. 2002 Jun;117(3):650-7.PMID: 12028038 [PubMed - indexed for MEDLINE]Related articles

Reduction of non-endothelial cell contamination of microvascular endothelial cell seeded grafts decreases thrombogenicity and intimal hyperplasia.

Arts CH, Blankensteijn JD, Heijnen-Snyder GJ, Verhagen HJ, Hedeman Joosten PP, Sixma JJ, Eikelboom BC, de Groot PG.

Eur J Vasc Endovasc Surg. 2002 May;23(5):404-12.PMID: 12027467 [PubMed - indexed for MEDLINE]Related articles

Endothelial cell activation after subarachnoid hemorrhage.

Frijns CJ, Rinkel GJ, Castigliego D, Van Gijn J, Sixma JJ, Fijnheer R.

Neurosurgery. 2002 Jun;50(6):1223-9; discussion 1229-30.PMID: 12015839 [PubMed - indexed for MEDLINE]Related articles

Role of ADP receptor P2Y(12) in platelet adhesion and thrombus formation in flowing blood.

Remijn JA, Wu YP, Jeninga EH, IJsseldijk MJ, van Willigen G, de Groot PG, Sixma JJ, Nurden AT, Nurden P.

Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):686-91.PMID: 11950711 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional self-association of von Willebrand factor during platelet adhesion under flow.

Savage B, Sixma JJ, Ruggeri ZM.

Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):425-30. Epub 2001 Dec 26.PMID: 11756664 [PubMed - indexed for MEDLINE]Related articlesFree article

Contaminants from the transplant contribute to intimal hyperplasia associated with microvascular endothelial cell seeding.

Arts CH, Hedeman Joosten PP, Blankensteijn JD, Staal FJ, Ng PY, Heijnen-Snyder GJ, Sixma JJ, Verhagen HJ, de Groot PG, Eikelboom BC.

Eur J Vasc Endovasc Surg. 2002 Jan;23(1):29-38.PMID: 11748945 [PubMed - indexed for MEDLINE]Related articles

A novel method for isolating pure microvascular endothelial cells from subcutaneous fat tissue ideal for direct cell seeding.

Arts CH, Heijnen-Snyder GJ, Joosten PP, Verhagen HJ, Eikelboom BC, Sixma JJ, de Groot PG.

Lab Invest. 2001 Oct;81(10):1461-5. No abstract available. PMID: 11598159 [PubMed - indexed for MEDLINE]Related articles

The 33-kDa platelet alpha-granule membrane protein (GMP-33) is an N-terminal proteolytic fragment of thrombospondin.

Damas C, Vink T, Nieuwenhuis HK, Sixma JJ.

Thromb Haemost. 2001 Sep;86(3):887-93.PMID: 11583323 [PubMed - indexed for MEDLINE]Related articles

The structure of leech anti-platelet protein, an inhibitor of haemostasis.

Huizinga EG, Schouten A, Connolly TM, Kroon J, Sixma JJ, Gros P.

Acta Crystallogr D Biol Crystallogr. 2001 Aug;57(Pt 8):1071-8. Epub 2001 Jul 23.PMID: 11468390 [PubMed - indexed for MEDLINE]Related articles

Mutations on fibrinogen (gamma 316-322) are associated with reduction in platelet adhesion under flow conditions.

Remijn JA, Lounes KC, Hogan KA, Lord ST, Galanakis DK, Sixma JJ, De Groot PG.

Ann N Y Acad Sci. 2001;936:444-8. Review.PMID: 11460499 [PubMed - indexed for MEDLINE]Related articles

Excessive urinary albumin levels are associated with future cardiovascular mortality in postmenopausal women.

Roest M, Banga JD, Janssen WM, Grobbee DE, Sixma JJ, de Jong PE, de Zeeuw D, van Der Schouw YT.

Circulation. 2001 Jun 26;103(25):3057-61.PMID: 11425768 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of fibrinogen in afibrinogenemia results in large but loosely packed thrombi under flow conditions.

Remijn JA, Wu YP, Ijsseldijk MJ, Zwaginga JJ, Sixma JJ, de Groot PG.

Thromb Haemost. 2001 Apr;85(4):736-42.PMID: 11341513 [PubMed - indexed for MEDLINE]Related articles

Methylenetetrahydrofolate reductase 677 C/T genotype and cardiovascular disease mortality in postmenopausal women.

Roest M, van der Schouw YT, Grobbee DE, Tempelman MJ, de Groot PG, Sixma JJ, Banga JD.

Am J Epidemiol. 2001 Apr 1;153(7):673-9.PMID: 11282795 [PubMed - indexed for MEDLINE]Related articlesFree article

Binding of von Willebrand factor to collagen type III: role of specific amino acids in the collagen binding domain of vWF and effects of neighboring domains.

van der Plas RM, Gomes L, Marquart JA, Vink T, Meijers JC, de Groot PG, Sixma JJ, Huizinga EG.

Thromb Haemost. 2000 Dec;84(6):1005-11.PMID: 11154106 [PubMed - indexed for MEDLINE]Related articles

Identification of the collagen-binding site of the von Willebrand factor A3-domain.

Romijn RA, Bouma B, Wuyster W, Gros P, Kroon J, Sixma JJ, Huizinga EG.

J Biol Chem. 2001 Mar 30;276(13):9985-91. Epub 2000 Nov 29.PMID: 11098050 [PubMed - indexed for MEDLINE]Related articlesFree article

Sequence alignment between vWF and peptides inhibiting the vWF-collagen interaction does not result in the identification of a collagen-binding site in vWF.

Vanhoorelbeke K, van der Plas RM, Vandecasteele G, Vauterin S, Huizinga EG, Sixma JJ, Deckmyn H.

Thromb Haemost. 2000 Oct;84(4):621-5.PMID: 11057860 [PubMed - indexed for MEDLINE]Related articles

Homozygosity for 807 T polymorphism in alpha(2) subunit of platelet alpha(2)beta(1) is associated with increased risk of cardiovascular mortality in high-risk women.

Roest M, Banga JD, Grobbee DE, de Groot PG, Sixma JJ, Tempelman MJ, van der Schouw YT.

Circulation. 2000 Oct 3;102(14):1645-50.PMID: 11015342 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein A is the von Willebrand factor binding protein on Staphylococcus aureus.

Hartleib J, Köhler N, Dickinson RB, Chhatwal GS, Sixma JJ, Hartford OM, Foster TJ, Peters G, Kehrel BE, Herrmann M.

Blood. 2000 Sep 15;96(6):2149-56.PMID: 10979960 [PubMed - indexed for MEDLINE]Related articlesFree article

Platelet adhesion to collagen in healthy volunteers is influenced by variation of both alpha(2)beta(1) density and von Willebrand factor.

Roest M, Sixma JJ, Wu YP, Ijsseldijk MJ, Tempelman M, Slootweg PJ, de Groot PG, van Zanten GH.

Blood. 2000 Aug 15;96(4):1433-7.PMID: 10942388 [PubMed - indexed for MEDLINE]Related articlesFree article

Platelet thrombus formation on collagen at high shear rates is mediated by von Willebrand factor-glycoprotein Ib interaction and inhibited by von Willebrand factor-glycoprotein IIb/IIIa interaction.

Wu YP, Vink T, Schiphorst M, van Zanten GH, IJsseldijk MJ, de Groot PG, Sixma JJ.

Arterioscler Thromb Vasc Biol. 2000 Jun;20(6):1661-7.PMID: 10845886 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibronectin in an extracellular matrix of cultured endothelial cells supports platelet adhesion via its ninth type III repeat : A comparison with platelet adhesion to isolated fibronectin

Beumer S, Heijnen-Snyder GJ, IJsseldijk MJ, de Groot PG, Sixma JJ.

Arterioscler Thromb Vasc Biol. 2000 Apr;20(4):E16-25.PMID: 10764693 [PubMed - as supplied by publisher]Related articlesFree article

The half-life of infused factor VIII is shorter in hemophiliac patients with blood group O than in those with blood group A.

Vlot AJ, Mauser-Bunschoten EP, Zarkova AG, Haan E, Kruitwagen CL, Sixma JJ, van den Berg HM.

Thromb Haemost. 2000 Jan;83(1):65-9.PMID: 10669157 [PubMed - indexed for MEDLINE]Related articles

Plasminogen activator inhibitor 4G polymorphism is associated with decreased risk of cerebrovascular mortality in older women.

Roest M, van der Schouw YT, Banga JD, Tempelman MJ, de Groot PG, Sixma JJ, Grobbee DE.

Circulation. 2000 Jan 4-11;101(1):67-70.PMID: 10618306 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules.

Heijnen HF, Schiel AE, Fijnheer R, Geuze HJ, Sixma JJ.

Blood. 1999 Dec 1;94(11):3791-9.PMID: 10572093 [PubMed - indexed for MEDLINE]Related articlesFree article

Adhesive domains in the collagen III fragment alpha1(III)CB4 that support alpha2beta1- and von Willebrand factor-mediated platelet adhesion under flow conditions.

Verkleij MW, IJsseldijk MJ, Heijnen-Snyder GJ, Huizinga EG, Morton LF, Knight CG, Sixma JJ, de Groot PG, Barnes MJ.

Thromb Haemost. 1999 Sep;82(3):1137-44.PMID: 10494778 [PubMed - indexed for MEDLINE]Related articles

Heterozygosity for a hereditary hemochromatosis gene is associated with cardiovascular death in women.

Roest M, van der Schouw YT, de Valk B, Marx JJ, Tempelman MJ, de Groot PG, Sixma JJ, Banga JD.

Circulation. 1999 Sep 21;100(12):1268-73.PMID: 10491369 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant vWF type 2A mutants R834Q and R834W show a defect in mediating platelet adhesion to collagen, independent of enhanced sensitivity to a plasma protease.

Lankhof H, Damas C, Schiphorst ME, Ijsseldijk MJ, Bracke M, Furlan M, de Groot PG, Sixma JJ, Vink T.

Thromb Haemost. 1999 Jun;81(6):976-83.PMID: 10404778 [PubMed - indexed for MEDLINE]Related articles

Minimal platelet deposition and activation in models of injured vessel wall ensure optimal neutrophil adhesion under flow conditions.

Zwaginga JJ, Torres HI, Lammers J, Sixma JJ, Koenderman L, Kuijper PH.

Arterioscler Thromb Vasc Biol. 1999 Jun;19(6):1549-54.PMID: 10364088 [PubMed - indexed for MEDLINE]Related articlesFree article

von Willebrand factor proteolysis is deficient in classic, but not in bone marrow transplantation-associated, thrombotic thrombocytopenic purpura.

van der Plas RM, Schiphorst ME, Huizinga EG, Hené RJ, Verdonck LF, Sixma JJ, Fijnheer R.

Blood. 1999 Jun 1;93(11):3798-802.PMID: 10339486 [PubMed - indexed for MEDLINE]Related articlesFree article

Thrombomodulin activity of fat-derived microvascular endothelial cells seeded on expanded polytetrafluorethylene.

Hedeman Joosten PP, Verhagen HJ, Heijnen-Snyder GJ, Sixma JJ, de Groot PG, Eikelboom BC, Elisen MG.

J Vasc Res. 1999 Mar-Apr;36(2):91-9.PMID: 10213903 [PubMed - indexed for MEDLINE]Related articles

Factor V Arg506Gln mutation is not associated with cardiovascular mortality in older women.

Roest M, Banga JD, Tempelman MJ, de Groot PG, Grobbee DE, Sixma JJ, van der Schouw YT.

Am J Epidemiol. 1999 Apr 1;149(7):665-70.PMID: 10192314 [PubMed - indexed for MEDLINE]Related articlesFree article

Platelet adhesion to the subendothelium under flow.

de Groot PG, IJsseldijk MJ, Sixma JJ.

Methods Mol Biol. 1999;96:159-70. Review. No abstract available. PMID: 10098134 [PubMed - indexed for MEDLINE]Related articles

A new perfusion chamber to detect platelet adhesion using a small volume of blood.

Sixma JJ, de Groot PG, van Zanten H, IJsseldijk M.

Thromb Res. 1998 Dec 15;92(6 Suppl 2):S43-6.PMID: 9886909 [PubMed - indexed for MEDLINE]Related articles

Thrombogenesis of different cell types seeded on vascular grafts and studied under blood-flow conditions.

Hedeman Joosten PP, Verhagen HJ, Heijnen-Snyder GJ, van Vroonhoven TJ, Sixma JJ, de Groot PG, Eikelboom BC.

J Vasc Surg. 1998 Dec;28(6):1094-103.PMID: 9845661 [PubMed - indexed for MEDLINE]Related articles

Platelet associated fibrinogen and ICAM-2 induce firm adhesion of neutrophils under flow conditions.

Kuijper PH, Gallardo Tores HI, Lammers JW, Sixma JJ, Koenderman L, Zwaginga JJ.

Thromb Haemost. 1998 Sep;80(3):443-8.PMID: 9759625 [PubMed - indexed for MEDLINE]Related articles

In vivo experiments with mesothelial cell seeded ePTFE vascular grafts.

Verhagen HJ, Blankensteijn JD, de Groot PG, Heijnen-Snyder GJ, Pronk A, Vroom TM, Muller HJ, Nicolay K, van Vroonhoven TJ, Sixma JJ, Eikelboom BC.

Eur J Vasc Endovasc Surg. 1998 Jun;15(6):489-96.PMID: 9659883 [PubMed - indexed for MEDLINE]Related articles

Simple collagen-like peptides support platelet adhesion under static but not under flow conditions: interaction via alpha2 beta1 and von Willebrand factor with specific sequences in native collagen is a requirement to resist shear forces.

Verkleij MW, Morton LF, Knight CG, de Groot PG, Barnes MJ, Sixma JJ.

Blood. 1998 May 15;91(10):3808-16.PMID: 9573018 [PubMed - indexed for MEDLINE]Related articlesFree article

A fifty percent reduction of platelet surface glycoprotein Ib does not affect platelet adhesion under flow conditions.

van Zanten GH, Heijnen HF, Wu Y, Schut-Hese KM, Slootweg PJ, de Groot PG, Sixma JJ, Nieuwland R.

Blood. 1998 Apr 1;91(7):2353-9.PMID: 9516134 [PubMed - indexed for MEDLINE]Related articlesFree article

Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules.

Heijnen HF, Debili N, Vainchencker W, Breton-Gorius J, Geuze HJ, Sixma JJ.

Blood. 1998 Apr 1;91(7):2313-25.PMID: 9516129 [PubMed - indexed for MEDLINE]Related articlesFree article

Factor VIII and von Willebrand factor.

Vlot AJ, Koppelman SJ, Bouma BN, Sixma JJ.

Thromb Haemost. 1998 Mar;79(3):456-65. Review. No abstract available. PMID: 9531024 [PubMed - indexed for MEDLINE]Related articles

Shear-stress-induced detachment of blood platelets from various surfaces.

Wu YP, de Groot PG, Sixma JJ.

Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):3202-7.PMID: 9409312 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycated proteins modulate tissue-plasminogen activator-catalyzed plasminogen activation.

Bobbink IW, Tekelenburg WL, Sixma JJ, de Boer HC, Banga JD, de Groot PG.

Biochem Biophys Res Commun. 1997 Nov 26;240(3):595-601.PMID: 9398610 [PubMed - indexed for MEDLINE]Related articles

Soluble adhesion molecules reflect endothelial cell activation in ischemic stroke and in carotid atherosclerosis.

Frijns CJ, Kappelle LJ, van Gijn J, Nieuwenhuis HK, Sixma JJ, Fijnheer R.

Stroke. 1997 Nov;28(11):2214-8.PMID: 9368567 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of von Willebrand factor with Staphylococcus aureus.

Herrmann M, Hartleib J, Kehrel B, Montgomery RR, Sixma JJ, Peters G.

J Infect Dis. 1997 Oct;176(4):984-91.PMID: 9333157 [PubMed - indexed for MEDLINE]Related articles