PubMed

Familial Combined Hyperlipidemia Is Associated With Alterations in the Cholesterol Synthesis Pathway.

van Himbergen TM, Otokozawa S, Matthan NR, Schaefer EJ, Buchsbaum A, Ai M, van Tits LJ, de Graaf J, Stalenhoef AF.

Arterioscler Thromb Vasc Biol. 2009 Oct 15. [Epub ahead of print]PMID: 19834104 [PubMed - as supplied by publisher]Related articles

Limitations of automated remnant lipoprotein cholesterol assay for diagnostic use.

Schaefer EJ.

Clin Chem. 2009 Nov;55(11):2061-2; author reply 2062-3. Epub 2009 Sep 17. No abstract available. PMID: 19762450 [PubMed - indexed for MEDLINE]Related articles

Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and Heart disease risk in the elderly.

Polisecki E, Peter I, Simon JS, Hegele RA, Robertson M, Ford I, Shepherd J, Packard C, Jukema JW, Decraen AJ, Westendorp RG, Buckley BM, Schaefer EJ.

J Lipid Res. 2009 Sep 14. [Epub ahead of print]PMID: 19752398 [PubMed - as supplied by publisher]Related articlesFree article

Fasting and postprandial apolipoprotein B-48 levels in healthy, obese, and hyperlipidemic subjects.

Otokozawa S, Ai M, Diffenderfer MR, Asztalos BF, Tanaka A, Lamon-Fava S, Schaefer EJ.

Metabolism. 2009 Nov;58(11):1536-42. Epub 2009 Jul 9.PMID: 19592048 [PubMed - indexed for MEDLINE]Related articles

Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: Insights from the PROSPER trial.

Matthan NR, Resteghini N, Robertson M, Ford I, Shepherd J, Packard C, Buckley BM, Jukema JW, Lichtenstein AH, Schaefer EJ.

J Lipid Res. 2009 Jul 3. [Epub ahead of print]PMID: 19578163 [PubMed - as supplied by publisher]Related articlesFree article

Association of polymorphisms in genes involved in lipoprotein metabolism with plasma concentrations of remnant lipoproteins and HDL subpopulations before and after hormone therapy in postmenopausal women.

Lamon-Fava S, Asztalos BF, Howard TD, Reboussin DM, Horvath KV, Schaefer EJ, Herrington DM.

Clin Endocrinol (Oxf). 2009 May 29. [Epub ahead of print]PMID: 19489872 [PubMed - as supplied by publisher]Related articles

Marked high density lipoprotein deficiency due to apolipoprotein A-I Tomioka (codon 138 deletion).

Wada M, Iso T, Asztalos BF, Takama N, Nakajima T, Seta Y, Kaneko K, Taniguchi Y, Kobayashi H, Nakajima K, Schaefer EJ, Kurabayashi M.

Atherosclerosis. 2009 Nov;207(1):157-61. Epub 2009 Apr 24.PMID: 19473658 [PubMed - in process]Related articles

Glycated albumin and direct low density lipoprotein cholesterol levels in type 2 diabetes mellitus.

Ai M, Otokozawa S, Schaefer EJ, Asztalos BF, Nakajima K, Shrader P, Kathiresan S, Meigs JB, Williams G, Nathan DM.

Clin Chim Acta. 2009 Aug;406(1-2):71-4. Epub 2009 May 22.PMID: 19465013 [PubMed - indexed for MEDLINE]Related articles

Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women.

Asztalos BF, Swarbrick MM, Schaefer EJ, Dallal GE, Horvath KV, Ai M, Stanhope KL, Austrheim-Smith I, Wolfe BM, Ali M, Havel PJ.

J Lipid Res. 2009 May 14. [Epub ahead of print]PMID: 19443861 [PubMed - as supplied by publisher]Related articlesFree article

Alterations in cholesterol absorption and synthesis characterize Framingham offspring study participants with coronary heart disease.

Matthan NR, Pencina M, Larocque JM, Jacques PF, D'Agostino RB, Schaefer EJ, Lichtenstein AH.

J Lipid Res. 2009 May 12. [Epub ahead of print]PMID: 19436064 [PubMed - as supplied by publisher]Related articlesFree article

Substitution of vegetable oil for a partially-hydrogenated fat favorably alters cardiovascular disease risk factors in moderately hypercholesterolemic postmenopausal women.

Vega-López S, Matthan NR, Ausman LM, Ai M, Otokozawa S, Schaefer EJ, Lichtenstein AH.

Atherosclerosis. 2009 Nov;207(1):208-12. Epub 2009 Apr 5.PMID: 19423109 [PubMed - in process]Related articles

Dietary fructose and glucose differentially affect lipid and glucose homeostasis.

Schaefer EJ, Gleason JA, Dansinger ML.

J Nutr. 2009 Jun;139(6):1257S-1262S. Epub 2009 Apr 29. Review.PMID: 19403705 [PubMed - indexed for MEDLINE]Related articles

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans.

Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ.

J Clin Invest. 2009 May;119(5):1322-34. doi: 10.1172/JCI37385. Epub 2009 Apr 20.PMID: 19381015 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of intensive atorvastatin and rosuvastatin treatment on apolipoprotein B-48 and remnant lipoprotein cholesterol levels.

Otokozawa S, Ai M, Van Himbergen T, Asztalos BF, Tanaka A, Stein EA, Jones PH, Schaefer EJ.

Atherosclerosis. 2009 Jul;205(1):197-201. Epub 2008 Nov 12.PMID: 19200542 [PubMed - indexed for MEDLINE]Related articles

Effects of cholesteryl ester transfer protein inhibition on apolipoprotein A-II-containing HDL subspecies and apolipoprotein A-II metabolism.

Brousseau ME, Millar JS, Diffenderfer MR, Nartsupha C, Asztalos BF, Wolfe ML, Mancuso JP, Digenio AG, Rader DJ, Schaefer EJ.

J Lipid Res. 2009 Jul;50(7):1456-62. Epub 2009 Feb 3.PMID: 19193611 [PubMed - in process]Related articles

Changes in remnant and high-density lipoproteins associated with hormone therapy and progression of coronary artery disease in postmenopausal women.

Lamon-Fava S, Herrington DM, Reboussin DM, Sherman M, Horvath K, Schaefer EJ, Asztalos BF.

Atherosclerosis. 2009 Jul;205(1):325-30. Epub 2008 Dec 24.PMID: 19155011 [PubMed - indexed for MEDLINE]Related articles

Serum lipid and antioxidant responses in hypercholesterolemic men and women receiving plant sterol esters vary by apolipoprotein E genotype.

Sanchez-Muniz FJ, Maki KC, Schaefer EJ, Ordovas JM.

J Nutr. 2009 Jan;139(1):13-9. Epub 2008 Dec 3.PMID: 19056656 [PubMed - indexed for MEDLINE]Related articles

Comparison of the effects of maximal dose atorvastatin and rosuvastatin therapy on cholesterol synthesis and absorption markers.

van Himbergen TM, Matthan NR, Resteghini NA, Otokozawa S, Ai M, Stein EA, Jones PH, Schaefer EJ.

J Lipid Res. 2009 Apr;50(4):730-9. Epub 2008 Nov 30.PMID: 19043140 [PubMed - indexed for MEDLINE]Related articles

Gender-specific differences in the kinetics of nonfasting TRL, IDL, and LDL apolipoprotein B-100 in men and premenopausal women.

Matthan NR, Jalbert SM, Barrett PH, Dolnikowski GG, Schaefer EJ, Lichtenstein AH.

Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1838-43. Epub 2008 Jul 24.PMID: 18658047 [PubMed - indexed for MEDLINE]Related articlesFree article

Extended-release niacin alters the metabolism of plasma apolipoprotein (Apo) A-I and ApoB-containing lipoproteins.

Lamon-Fava S, Diffenderfer MR, Barrett PH, Buchsbaum A, Nyaku M, Horvath KV, Asztalos BF, Otokozawa S, Ai M, Matthan NR, Lichtenstein AH, Dolnikowski GG, Schaefer EJ.

Arterioscler Thromb Vasc Biol. 2008 Sep;28(9):1672-8. Epub 2008 Jun 19.PMID: 18566298 [PubMed - indexed for MEDLINE]Related articlesFree article

Relative atherogenicity and predictive value of non-high-density lipoprotein cholesterol for coronary heart disease.

Miller M, Ginsberg HN, Schaefer EJ.

Am J Cardiol. 2008 Apr 1;101(7):1003-8. Review.PMID: 18359322 [PubMed - indexed for MEDLINE]Related articles

Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population.

Polisecki E, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Blauw GJ, Westendorp RG, de Craen AJ, Trompet S, Buckley BM, Murphy MB, Ordovas JM, Schaefer EJ; PROSPER Study Group.

Atherosclerosis. 2008 Sep;200(1):95-101. Epub 2008 Feb 8.PMID: 18262190 [PubMed - indexed for MEDLINE]Related articles

Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.

Polisecki E, Muallem H, Maeda N, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Westendorp RG, de Craen AJ, Buckley BM, Ordovas JM, Schaefer EJ; Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Investigators.

Atherosclerosis. 2008 Sep;200(1):109-14. Epub 2008 Feb 7.PMID: 18261733 [PubMed - indexed for MEDLINE]Related articles

Effects of maximal doses of atorvastatin versus rosuvastatin on small dense low-density lipoprotein cholesterol levels.

Ai M, Otokozawa S, Asztalos BF, Nakajima K, Stein E, Jones PH, Schaefer EJ.

Am J Cardiol. 2008 Feb 1;101(3):315-8. Epub 2007 Dec 20.PMID: 18237592 [PubMed - indexed for MEDLINE]Related articles

Plasma levels of HDL subpopulations and remnant lipoproteins predict the extent of angiographically-defined coronary artery disease in postmenopausal women.

Lamon-Fava S, Herrington DM, Reboussin DM, Sherman M, Horvath KV, Cupples LA, White C, Demissie S, Schaefer EJ, Asztalos BF.

Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):575-9. Epub 2008 Jan 3.PMID: 18174456 [PubMed - indexed for MEDLINE]Related articlesFree article

Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives.

Harris WS, Miller M, Tighe AP, Davidson MH, Schaefer EJ.

Atherosclerosis. 2008 Mar;197(1):12-24. Epub 2007 Dec 26. Review.PMID: 18160071 [PubMed - indexed for MEDLINE]Related articles

Relation of gemfibrozil treatment and high-density lipoprotein subpopulation profile with cardiovascular events in the Veterans Affairs High-Density Lipoprotein Intervention Trial.

Asztalos BF, Collins D, Horvath KV, Bloomfield HE, Robins SJ, Schaefer EJ.

Metabolism. 2008 Jan;57(1):77-83.PMID: 18078862 [PubMed - indexed for MEDLINE]Related articlesFree article

Increasing high-density lipoprotein cholesterol, inhibition of cholesteryl ester transfer protein, and heart disease risk reduction.

Schaefer EJ, Asztalos BF.

Am J Cardiol. 2007 Dec 3;100(11 A):n25-31. Review.PMID: 18047849 [PubMed - indexed for MEDLINE]Related articles

Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on VLDL apolipoprotein E metabolism.

Millar JS, Brousseau ME, Diffenderfer MR, Barrett PH, Welty FK, Cohn JS, Wilson A, Wolfe ML, Nartsupha C, Schaefer PM, Digenio AG, Mancuso JP, Dolnikowski GG, Schaefer EJ, Rader DJ.

J Lipid Res. 2008 Mar;49(3):543-9. Epub 2007 Nov 21.PMID: 18033754 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of high density lipoprotein particles in familial apolipoprotein A-I deficiency.

Santos RD, Schaefer EJ, Asztalos BF, Polisecki E, Wang J, Hegele RA, Martinez LR, Miname MH, Rochitte CE, Da Luz PL, Maranhão RC.

J Lipid Res. 2008 Feb;49(2):349-57. Epub 2007 Nov 8.PMID: 17991756 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-invasive detection of aortic and coronary atherosclerosis in homozygous familial hypercholesterolemia by 64 slice multi-detector row computed tomography angiography.

Santos RD, Miname MH, Martinez LR, Rochitte CE, Chacra AP, Nakandakare ER, Chen D, Schaefer EJ.

Atherosclerosis. 2008 Apr;197(2):910-5. Epub 2007 Sep 19.PMID: 17884061 [PubMed - indexed for MEDLINE]Related articles

Effects of age and gender on physical performance.

Bongard V, McDermott AY, Dallal GE, Schaefer EJ.

Age (Dordr). 2007 Sep;29(2-3):77-85. Epub 2007 Jun 23.PMID: 19424833 [PubMed - in process]Related articlesFree article

Clinical utility of different lipid measures for prediction of coronary heart disease in men and women.

Ingelsson E, Schaefer EJ, Contois JH, McNamara JR, Sullivan L, Keyes MJ, Pencina MJ, Schoonmaker C, Wilson PW, D'Agostino RB, Vasan RS.

JAMA. 2007 Aug 15;298(7):776-85.PMID: 17699011 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypertriglyceridemia and cardiovascular risk reduction.

Jacobson TA, Miller M, Schaefer EJ.

Clin Ther. 2007 May;29(5):763-77. Review.PMID: 17697898 [PubMed - indexed for MEDLINE]Related articles

Effect of body mass index on apolipoprotein A-I kinetics in middle-aged men and postmenopausal women.

Welty FK, Lichtenstein AH, Lamon-Fava S, Schaefer EJ, Marsh JB.

Metabolism. 2007 Jul;56(7):910-4.PMID: 17570251 [PubMed - indexed for MEDLINE]Related articlesFree article

Where are we with high-density lipoprotein raising and inhibition of cholesteryl ester transfer for heart disease risk reduction?

Schaefer EJ, Asztalos BF.

Curr Opin Cardiol. 2007 Jul;22(4):373-8. Review.PMID: 17556892 [PubMed - indexed for MEDLINE]Related articles

Effects of different doses of atorvastatin on human apolipoprotein B-100, B-48, and A-I metabolism.

Lamon-Fava S, Diffenderfer MR, Barrett PH, Buchsbaum A, Matthan NR, Lichtenstein AH, Dolnikowski GG, Horvath K, Asztalos BF, Zago V, Schaefer EJ.

J Lipid Res. 2007 Aug;48(8):1746-53. Epub 2007 May 27.PMID: 17526934 [PubMed - indexed for MEDLINE]Related articlesFree article

Oestrogen replacement therapy reduces total plasma homocysteine and enhances genomic DNA methylation in postmenopausal women.

Friso S, Lamon-Fava S, Jang H, Schaefer EJ, Corrocher R, Choi SW.

Br J Nutr. 2007 Apr;97(4):617-21.PMID: 17349072 [PubMed - indexed for MEDLINE]Related articles

Comparison of the effects of high doses of rosuvastatin versus atorvastatin on the subpopulations of high-density lipoproteins.

Asztalos BF, Le Maulf F, Dallal GE, Stein E, Jones PH, Horvath KV, McTaggart F, Schaefer EJ.

Am J Cardiol. 2007 Mar 1;99(5):681-5. Epub 2007 Jan 4.PMID: 17317371 [PubMed - indexed for MEDLINE]Related articles

Role of LCAT in HDL remodeling: investigation of LCAT deficiency states.

Asztalos BF, Schaefer EJ, Horvath KV, Yamashita S, Miller M, Franceschini G, Calabresi L.

J Lipid Res. 2007 Mar;48(3):592-9. Epub 2006 Dec 20.PMID: 17183024 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study.

Schaefer EJ, Bongard V, Beiser AS, Lamon-Fava S, Robins SJ, Au R, Tucker KL, Kyle DJ, Wilson PW, Wolf PA.

Arch Neurol. 2006 Nov;63(11):1545-50.PMID: 17101822 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk of cardiovascular disease in a cohort of HIV-infected adults: a study using carotid intima-media thickness and coronary artery calcium score.

Mangili A, Gerrior J, Tang AM, O'Leary DH, Polak JK, Schaefer EJ, Gorbach SL, Wanke CA.

Clin Infect Dis. 2006 Dec 1;43(11):1482-9. Epub 2006 Oct 31.PMID: 17083026 [PubMed - indexed for MEDLINE]Related articles

Novel soybean oils with different fatty acid profiles alter cardiovascular disease risk factors in moderately hyperlipidemic subjects.

Lichtenstein AH, Matthan NR, Jalbert SM, Resteghini NA, Schaefer EJ, Ausman LM.

Am J Clin Nutr. 2006 Sep;84(3):497-504.PMID: 16960162 [PubMed - indexed for MEDLINE]Related articlesFree article

Codon 54 polymorphism of the fatty acid binding protein (FABP) 2 gene is associated with increased cardiovascular risk in the dyslipidemic diabetic participants of the Veterans Affairs HDL intervention trial (VA-HIT).

Georgopoulos A, Bloomfield H, Collins D, Brousseau ME, Ordovas JM, O'Connor JJ, Robins SJ, Schaefer EJ.

Atherosclerosis. 2007 Sep;194(1):169-74. Epub 2006 Aug 30.PMID: 16945373 [PubMed - indexed for MEDLINE]Related articles

Should we target HDL-cholesterol to reduce coronary heart disease risk?

Schaefer EJ, Asztalos BF.

Nat Clin Pract Endocrinol Metab. 2006 Jul;2(7):358-9. Review. No abstract available. PMID: 16932315 [PubMed - indexed for MEDLINE]Related articles

Potential role of dietary n-3 fatty acids in the prevention of dementia and macular degeneration.

Johnson EJ, Schaefer EJ.

Am J Clin Nutr. 2006 Jun;83(6 Suppl):1494S-1498S. Review. Erratum in: Am J Clin Nutr. 2006 Dec;84(6):1555. PMID: 16841859 [PubMed - indexed for MEDLINE]Related articlesFree article

Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction.

Schaefer EJ, Asztalos BF.

Curr Opin Lipidol. 2006 Aug;17(4):394-8. Review.PMID: 16832162 [PubMed - indexed for MEDLINE]Related articles

Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on apolipoprotein B100 metabolism in humans.

Millar JS, Brousseau ME, Diffenderfer MR, Barrett PH, Welty FK, Faruqi A, Wolfe ML, Nartsupha C, Digenio AG, Mancuso JP, Dolnikowski GG, Schaefer EJ, Rader DJ.

Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1350-6. Epub 2006 Mar 30.PMID: 16574893 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial.

Otvos JD, Collins D, Freedman DS, Shalaurova I, Schaefer EJ, McNamara JR, Bloomfield HE, Robins SJ.

Circulation. 2006 Mar 28;113(12):1556-63. Epub 2006 Mar 13.PMID: 16534013 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-carbohydrate or low-fat diets for the metabolic syndrome?

Dansinger ML, Schaefer EJ.

Curr Diab Rep. 2006 Feb;6(1):55-63. Review.PMID: 16522282 [PubMed - indexed for MEDLINE]Related articles