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Diabetes Exacerbates the Functional Deficiency of NO/cGMP Pathway Associated with Erectile Dysfunction in Human Corpus Cavernosum and Penile Arteries.

Angulo J, González-Corrochano R, Cuevas P, Fernández A, Fuente JM, Rolo F, Allona A, Sáenz de Tejada I.

J Sex Med. 2009 Nov 12. [Epub ahead of print]PMID: 19912487 [PubMed - as supplied by publisher]Related articles

Calcium Dobesilate for the Treatment of Erectile Dysfunction in Men with Diabetes Mellitus.

Videla S, Villoria J, Sust M, Drábek F, Všetička J, Pavlik I, Kawaciuk I, Louda M, García C, Angulo J, Sáenz de Tejada I.

Basic Clin Pharmacol Toxicol. 2008 Aug 18. [Epub ahead of print]PMID: 18713232 [PubMed - as supplied by publisher]Related articles

Vardenafil duration of action.

Sáenz de Tejada I.

Eur Urol. 2006 Nov;50(5):901-2. Epub 2006 Aug 8. No abstract available. PMID: 16949729 [PubMed - indexed for MEDLINE]Related articles

Physiology of erectile function.

Sáenz de Tejada I, Angulo J, Cellek S, González-Cadavid N, Heaton J, Pickard R, Simonsen U.

J Sex Med. 2004 Nov;1(3):254-65. Review.PMID: 16422955 [PubMed - indexed for MEDLINE]Related articles

Pathophysiology of erectile dysfunction.

Sáenz de Tejada I, Angulo J, Cellek S, González-Cadavid N, Heaton J, Pickard R, Simonsen U.

J Sex Med. 2005 Jan;2(1):26-39.PMID: 16422902 [PubMed - indexed for MEDLINE]Related articles

Enhancement of both EDHF and NO/cGMP pathways is necessary to reverse erectile dysfunction in diabetic rats.

Angulo J, Cuevas P, Gabancho S, Gonzalez-Corrochano R, Videla S, Saenz de Tejada I.

J Sex Med. 2005 May;2(3):341-6.PMID: 16422865 [PubMed - indexed for MEDLINE]Related articles

Sustained efficacy and tolerability with vardenafil over 2 years of treatment in men with erectile dysfunction.

Stief C, Porst H, Sáenz De Tejada I, Ulbrich E, Beneke M; Vardenafil Study Group.

Int J Clin Pract. 2004 Mar;58(3):230-9.PMID: 15117088 [PubMed - indexed for MEDLINE]Related articles

Mechanisms for the inhibition of genital vascular responses by antidepressants in a female rabbit model.

Angulo J, Cuevas P, Cuevas B, Gupta S, Sáenz de Tejada I.

J Pharmacol Exp Ther. 2004 Jul;310(1):141-9. Epub 2004 Mar 19.PMID: 15034084 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes impairs endothelium-dependent relaxation of human penile vascular tissues mediated by NO and EDHF.

Angulo J, Cuevas P, Fernández A, Gabancho S, Allona A, Martín-Morales A, Moncada I, Videla S, Sáenz de Tejada I.

Biochem Biophys Res Commun. 2003 Dec 26;312(4):1202-8.PMID: 14652001 [PubMed - indexed for MEDLINE]Related articles

Reperfusion of ischemic corporal tissue: physiologic and biochemical changes in an animal model of ischemic priapism.

Munarriz R, Park K, Huang YH, Saenz de Tejada I, Moreland RB, Goldstein I, Traish AM.

Urology. 2003 Oct;62(4):760-4.PMID: 14550468 [PubMed - indexed for MEDLINE]Related articles

Calcium dobesilate potentiates endothelium-derived hyperpolarizing factor-mediated relaxation of human penile resistance arteries.

Angulo J, Cuevas P, Fernández A, Gabancho S, Videla S, Sáenz de Tejada I.

Br J Pharmacol. 2003 Jun;139(4):854-62.PMID: 12813009 [PubMed - indexed for MEDLINE]Related articlesFree article

Vardenafil enhances clitoral and vaginal blood flow responses to pelvic nerve stimulation in female dogs.

Angulo J, Cuevas P, Cuevas B, Bischoff E, Sáenz de Tejada I.

Int J Impot Res. 2003 Apr;15(2):137-41.PMID: 12789394 [PubMed - indexed for MEDLINE]Related articles

Vardenafil reverses erectile dysfunction induced by paroxetine in rats.

Angulo J, Bischoff E, Gabancho S, Cuevas P, Sáenz de Tejada I.

Int J Impot Res. 2003 Apr;15(2):90-3.PMID: 12789386 [PubMed - indexed for MEDLINE]Related articles

[New contributions of the usefulness of electromyography of cavernous bodies in the diagnosis of erectile dysfunction]

Salinas Casado J, Vírseda Chamorro M, Saenz de Tejada I, Allona Almagro A, Ramírez Fernández JC, Litton Muñoz M.

Arch Esp Urol. 2003 Jan-Feb;56(1):61-8. Spanish. PMID: 12701482 [PubMed - indexed for MEDLINE]Related articles

Activation and potentiation of the NO/cGMP pathway by NG-hydroxyl-L-arginine in rabbit corpus cavernosum under normoxic and hypoxic conditions and ageing.

Angulo J, Cuevas P, Fernández A, Gabancho S, Allona A, Martín-Morales A, Moncada I, Sáenz de Tejada I.

Br J Pharmacol. 2003 Jan;138(1):63-70.PMID: 12522074 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of tadalafil on erectile dysfunction in men with diabetes.

Sáenz de Tejada I, Anglin G, Knight JR, Emmick JT.

Diabetes Care. 2002 Dec;25(12):2159-64.PMID: 12453954 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of human penile smooth muscle tone by prostanoid receptors.

Angulo J, Cuevas P, La Fuente JM, Pomerol JM, Ruiz-Castañé E, Puigvert A, Gabancho S, Fernández A, Ney P, Sáenz De Tejada I.

Br J Pharmacol. 2002 May;136(1):23-30.PMID: 11976264 [PubMed - indexed for MEDLINE]Related articlesFree article

The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil.

Saenz de Tejada I, Angulo J, Cuevas P, Fernández A, Moncada I, Allona A, Lledó E, Körschen HG, Niewöhner U, Haning H, Pages E, Bischoff E.

Int J Impot Res. 2001 Oct;13(5):282-90.PMID: 11890515 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanisms for the regulation of penile smooth muscle contractility.

Sáenz de Tejada I.

Int J Impot Res. 2002 Feb;14 Suppl 1:S6-10. Review.PMID: 11850728 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of serotonin reuptake inhibitors on erectile responses, NO-production, and neuronal NO synthase expression in rat corpus cavernosum tissue.

Angulo J, Peiró C, Sanchez-Ferrer CF, Gabancho S, Cuevas P, Gupta S, Sáenz de Tejada I.

Br J Pharmacol. 2001 Nov;134(6):1190-4.PMID: 11704638 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence and independent risk factors for erectile dysfunction in Spain: results of the Epidemiologia de la Disfuncion Erectil Masculina Study.

Martin-Morales A, Sanchez-Cruz JJ, Saenz de Tejada I, Rodriguez-Vela L, Jimenez-Cruz JF, Burgos-Rodriguez R.

J Urol. 2001 Aug;166(2):569-74; discussion 574-5.PMID: 11458070 [PubMed - indexed for MEDLINE]Related articles

Combination of phentolamine and L-arginine or sildenafil synergistically improves neurogenic relaxation of rabbit corpus cavernosum smooth muscle.

Angulo J, Cuevas P, Fernández A, Gabancho S, Saenz de Tejada I.

Urology. 2001 Mar;57(3):585-9.PMID: 11248652 [PubMed - indexed for MEDLINE]Related articles

Rationale for the combination of PGE(1) and S-nitroso-glutathione to induce relaxation of human penile smooth muscle.

Angulo J, Cuevas P, Moncada I, Martín-Morales A, Allona A, Fernández A, Gabancho S, Ney P, Sáenz de Tejada I.

J Pharmacol Exp Ther. 2000 Nov;295(2):586-93.PMID: 11046092 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mechanisms for the regulation of penile smooth muscle contractility.

Saenz de Tejada I.

Int J Impot Res. 2000 Oct;12 Suppl 4:S34-8. Review.PMID: 11035384 [PubMed - indexed for MEDLINE]Related articles

Regulation of pre-synaptic alpha adrenergic activity in the corpus cavernosum.

Saenz de Tejada I, Kim NN, Goldstein I, Traish AM.

Int J Impot Res. 2000 Mar;12 Suppl 1:S20-25. Review.PMID: 10845761 [PubMed - indexed for MEDLINE]Related articles

Pharmacological treatment of erectile dysfunction.

Moncada Iribarren I, Sáenz de Tejada I.

Curr Opin Urol. 1999 Nov;9(6):547-51. Review.PMID: 10668576 [PubMed - indexed for MEDLINE]Related articles

Fibroblast growth factor protects the kidney against ischemia-reperfusion injury.

Cuevas P, Martinez-Coso V, Fu X, Orte L, Reimers D, Giménez-Gallego G, Forssmann WG, Saenz De Tejada I.

Eur J Med Res. 1999 Oct 15;4(10):403-10.PMID: 10527953 [PubMed - indexed for MEDLINE]Related articles

Enhanced contractility of rabbit corpus cavernosum smooth muscle by oxidized low density lipoproteins.

Ahn TY, Gómez-Coronado D, Martínez V, Cuevas P, Goldstein I, Sáenz de Tejada I.

Int J Impot Res. 1999 Feb;11(1):9-14.PMID: 10098947 [PubMed - indexed for MEDLINE]Related articles

[Erectile dysfunction. An update]

Wagner G, Saenz de Tejada I.

Ugeskr Laeger. 1999 Mar 1;161(9):1243-8. Danish. PMID: 10083818 [PubMed - indexed for MEDLINE]Related articles

Relative roles of cyclooxygenase and nitric oxide synthase pathways in ischemia-induced increased contraction of cavernosal smooth muscle.

Azadzoi KM, Krane RJ, Saenz de Tejada I, Goldstein I, Siroky MB.

J Urol. 1999 Apr;161(4):1324-8.PMID: 10081902 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of ischemia-induced cavernosal smooth muscle relaxation impairment in a rabbit model of vasculogenic erectile dysfunction.

Azadzoi KM, Goldstein I, Siroky MB, Traish AM, Krane RJ, Saenz de Tejada I.

J Urol. 1998 Dec;160(6 Pt 1):2216-22.PMID: 9817373 [PubMed - indexed for MEDLINE]Related articles

Engineering analysis of penile hemodynamic and structural-dynamic relationships: Part III--Clinical considerations of penile hemodynamic and rigidity erectile responses.

Udelson D, Nehra A, Hatzichristou DG, Azadzoi K, Moreland RB, Krane RJ, Saenz de Tejada I, Goldstein I.

Int J Impot Res. 1998 Jun;10(2):89-99.PMID: 9647944 [PubMed - indexed for MEDLINE]Related articles

Engineering analysis of penile hemodynamic and structural-dynamic relationships: Part II--Clinical implications of penile buckling.

Udelson D, Nehra A, Hatzichristou DG, Azadzoi K, Moreland RB, Krane RJ, Saenz de Tejada I, Goldstein I.

Int J Impot Res. 1998 Mar;10(1):25-35.PMID: 9542687 [PubMed - indexed for MEDLINE]Related articles

Engineering analysis of penile hemodynamic and structural-dynamic relationships: Part I--Clinical implications of penile tissue mechanical properties.

Udelson D, Nehra A, Hatzichristou DG, Azadzoi K, Moreland RB, Krane J, Saenz de Tejada IS, Goldstein I.

Int J Impot Res. 1998 Mar;10(1):15-24.PMID: 9542686 [PubMed - indexed for MEDLINE]Related articles

Acidic fibroblast growth factor rescues gerbil hippocampal neurons from ischemic apoptotic death.

Cuevas P, Carceller F, Reimers D, Saenz de Tejada I, Giménez-Gallego G.

Neurol Res. 1998 Apr;20(3):271-4.PMID: 9583591 [PubMed - indexed for MEDLINE]Related articles

A possible mechanism for alteration of human erectile function by digoxin: inhibition of corpus cavernosum sodium/potassium adenosine triphosphatase activity.

Gupta S, Salimpour P, Saenz de Tejada I, Daley J, Gholami S, Daller M, Krane RJ, Traish AM, Goldstein I.

J Urol. 1998 May;159(5):1529-36.PMID: 9554348 [PubMed - indexed for MEDLINE]Related articles

Surgical trauma on the tunica albuginea.

Sáenz de Tejada I.

J Urol. 1998 May;159(5):1430. No abstract available. PMID: 9554327 [PubMed - indexed for MEDLINE]Related articles

Update on male erectile dysfunction.

Wagner G, Saenz de Tejada I.

BMJ. 1998 Feb 28;316(7132):678-82. Review. No abstract available. PMID: 9522795 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibroblast growth factor-1 prevents myocardial apoptosis triggered by ischemia reperfusion injury.

Cuevas P, Reimers D, Carceller F, Martinez-Coso V, Redondo-Horcajo M, Saenz de Tejada I, Giménez-Gallego G.

Eur J Med Res. 1997 Nov 28;2(11):465-8.PMID: 9385115 [PubMed - indexed for MEDLINE]Related articles

Kinins are implicated of the hypotensive effect of acidic fibroblast growth factor.

Saenz de Tejada I, Carceller F, Fernandez A, Cuevas B, Ortes L, Giménez-Gallego G, Cuevas P.

Eur J Med Res. 1997 Jul 28;2(7):302-4.PMID: 9233905 [PubMed - indexed for MEDLINE]Related articles

Prejunctional alpha 2-adrenoceptors inhibit nitrergic neurotransmission in horse penile resistance arteries.

Simonsen U, Prieto D, Hernández M, Sáenz de Tejada I, García-Sacristán A.

J Urol. 1997 Jun;157(6):2356-60.PMID: 9146670 [PubMed - indexed for MEDLINE]Related articles

Functional and radiologic evidence of vascular communication between the spongiosal and cavernosal compartments of the penis.

Vardi Y, Saenz de Tejada I.

Urology. 1997 May;49(5):749-52.PMID: 9145982 [PubMed - indexed for MEDLINE]Related articles

Adrenoceptor-mediated regulation of the contractility in horse penile resistance arteries.

Simonsen U, Prieto D, Hernández M, Sáenz de Tejada I, García-Sacristán A.

J Vasc Res. 1997 Mar-Apr;34(2):90-102.PMID: 9167641 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide is involved in the inhibitory neurotransmission and endothelium-dependent relaxations of human small penile arteries.

Simonsen U, Prieto D, Delgado JA, Hernández M, Resel L, Saenz de Tejada I, García-Sacristán A.

Clin Sci (Lond). 1997 Mar;92(3):269-75.PMID: 9093007 [PubMed - indexed for MEDLINE]Related articles

Acidosis impairs rabbit trabecular smooth muscle contractility.

Saenz de Tejada I, Kim NN, Daley JT, Royai R, Hypolite J, Broderick GA, Garcia-Diaz F, Levin R.

J Urol. 1997 Feb;157(2):722-6.PMID: 8996406 [PubMed - indexed for MEDLINE]Related articles

Altered contractility of urinary bladder in diabetic rabbits: relationship to reduced Na+ pump activity.

Gupta S, Yang S, Cohen RA, Krane RJ, Saenz De Tejada I.

Am J Physiol. 1996 Dec;271(6 Pt 1):C2045-52.PMID: 8997207 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of venous leakage: a prospective clinicopathological correlation of corporeal function and structure.

Nehra A, Goldstein I, Pabby A, Nugent M, Huang YH, de las Morenas A, Krane RJ, Udelson D, Saenz de Tejada I, Moreland RB.

J Urol. 1996 Oct;156(4):1320-9.PMID: 8808863 [PubMed - indexed for MEDLINE]Related articles

Prostanoid production in rabbit corpus cavernosum. II. Inhibition by oxidative stress.

Daley JT, Watkins MT, Brown ML, Martinez V, Cuevas P, Saenz de Tejada I.

J Urol. 1996 Sep;156(3):1169-73.PMID: 8709340 [PubMed - indexed for MEDLINE]Related articles

Analgesic effects of fibroblast growth factor in the rat.

Cuevas P, Prieto R, Saenz de Tejada I, Giménez-Gallego G.

Neurosci Lett. 1996 Apr 5;207(3):175-8.PMID: 8728478 [PubMed - indexed for MEDLINE]Related articles

Altered contractility of rabbit penile corpus cavernosum smooth muscle by hypoxia.

Kim NN, Kim JJ, Hypolite J, García-Díaz JF, Broderick GA, Tornheim K, Daley JT, Levin R, Saenz de Tejada I.

J Urol. 1996 Feb;155(2):772-8.PMID: 8558723 [PubMed - indexed for MEDLINE]Related articles