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The protective effect of simvastatin against low dose streptozotocin induced type 1 diabetes in mice is independent of inhibition of HMG-CoA reductase.
Rydgren T, Sandler S.
Biochem Biophys Res Commun. 2009 Feb 20;379(4):1076-9. Epub 2009 Jan 14.PMID: 19150339 [PubMed - indexed for MEDLINE]Related articles
Simvastatin protects against multiple low-dose streptozotocin-induced type 1 diabetes in CD-1 mice and recurrence of disease in nonobese diabetic mice.
Rydgren T, Vaarala O, Sandler S.
J Pharmacol Exp Ther. 2007 Oct;323(1):180-5. Epub 2007 Jul 17.PMID: 17636011 [PubMed - indexed for MEDLINE]Related articlesFree article
Complete protection against interleukin-1beta-induced functional suppression and cytokine-mediated cytotoxicity in rat pancreatic islets in vitro using an interleukin-1 cytokine trap.
Rydgren T, Bengtsson D, Sandler S.
Diabetes. 2006 May;55(5):1407-12.PMID: 16644698 [PubMed - indexed for MEDLINE]Related articlesFree article
Efficacy of 1400 W, a novel inhibitor of inducible nitric oxide synthase, in preventing interleukin-1beta-induced suppression of pancreatic islet function in vitro and multiple low-dose streptozotocin-induced diabetes in vivo.
Eur J Endocrinol. 2002 Oct;147(4):543-51.PMID: 12370118 [PubMed - indexed for MEDLINE]Related articlesFree article
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