PubMed

ChREBP is a Negative Regulator of ARNT/HIF-1{beta} Gene Expression in Pancreatic Islet {beta}-Cells.

Noordeen NA, Khera TK, Sun G, Longbottom ER, Pullen TJ, da Silva Xavier G, Rutter GA, Leclerc I.

Diabetes. 2009 Oct 15. [Epub ahead of print]PMID: 19833882 [PubMed - as supplied by publisher]Related articles

Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis.

Vinkenborg JL, Nicolson TJ, Bellomo EA, Koay MS, Rutter GA, Merkx M.

Nat Methods. 2009 Oct;6(10):737-40. Epub 2009 Aug 30.PMID: 19718032 [PubMed - indexed for MEDLINE]Related articles

A role for the CREB co-activator CRTC2 in the hypothalamic mechanisms linking glucose sensing with gene regulation.

Lerner RG, Depatie C, Rutter GA, Screaton RA, Balthasar N.

EMBO Rep. 2009 Oct;10(10):1175-81. Epub 2009 Aug 28.PMID: 19713961 [PubMed - in process]Related articles

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

Lemaire K, Ravier MA, Schraenen A, Creemers JW, Van de Plas R, Granvik M, Van Lommel L, Waelkens E, Chimienti F, Rutter GA, Gilon P, in't Veld PA, Schuit FC.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7. Epub 2009 Aug 18.PMID: 19706465 [PubMed - indexed for MEDLINE]Related articles

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA.

Diabetes. 2009 Sep;58(9):2070-83. Epub 2009 Jun 19.PMID: 19542200 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial calcium as a key regulator of mitochondrial ATP production in mammalian cells.

Griffiths EJ, Rutter GA.

Biochim Biophys Acta. 2009 Nov;1787(11):1324-33. Epub 2009 Feb 3. Review.PMID: 19366607 [PubMed - indexed for MEDLINE]Related articles

Regulating glucagon secretion: somatostatin in the spotlight.

Rutter GA.

Diabetes. 2009 Feb;58(2):299-301. No abstract available. PMID: 19171745 [PubMed - indexed for MEDLINE]Related articlesFree article

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells.

da Silva Xavier G, Loder MK, McDonald A, Tarasov AI, Carzaniga R, Kronenberger K, Barg S, Rutter GA.

Diabetes. 2009 Apr;58(4):894-905. Epub 2009 Jan 23.PMID: 19168596 [PubMed - indexed for MEDLINE]Related articlesFree article

Imaging a target of Ca2+ signalling: dense core granule exocytosis viewed by total internal reflection fluorescence microscopy.

Ravier MA, Tsuboi T, Rutter GA.

Methods. 2008 Nov;46(3):233-8. Epub 2008 Oct 12.PMID: 18854212 [PubMed - indexed for MEDLINE]Related articlesFree article

The AMP-regulated kinase family: enigmatic targets for diabetes therapy.

Rutter GA, Leclerc I.

Mol Cell Endocrinol. 2009 Jan 15;297(1-2):41-9. Epub 2008 Jun 19. Review.PMID: 18611432 [PubMed - indexed for MEDLINE]Related articles

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M.

J Cell Sci. 2008 Jul 15;121(Pt 14):2308-18. Epub 2008 Jun 17.PMID: 18559892 [PubMed - indexed for MEDLINE]Related articlesFree article

TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells.

Loder MK, da Silva Xavier G, McDonald A, Rutter GA.

Biochem Soc Trans. 2008 Jun;36(Pt 3):357-9.PMID: 18481957 [PubMed - indexed for MEDLINE]Related articles

The pancreatic beta-cell: birth, life and death.

Rutter GA, Wong FS.

Biochem Soc Trans. 2008 Jun;36(Pt 3):267-71.PMID: 18481939 [PubMed - indexed for MEDLINE]Related articles

A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.

Tarasov AI, Nicolson TJ, Riveline JP, Taneja TK, Baldwin SA, Baldwin JM, Charpentier G, Gautier JF, Froguel P, Vaxillaire M, Rutter GA.

Diabetes. 2008 Jun;57(6):1595-604. Epub 2008 Mar 17.PMID: 18346985 [PubMed - indexed for MEDLINE]Related articlesFree article

Ca2+ signalling: a new route to NAADP.

Rutter GA, Bellomo EA.

Biochem J. 2008 Apr 1;411(1):e1-3. Review.PMID: 18333834 [PubMed - indexed for MEDLINE]Related articlesFree article

The beta-cell in type 2 diabetes and in obesity.

Rutter GA, Parton LE.

Front Horm Res. 2008;36:118-34. Review.PMID: 18230899 [PubMed - indexed for MEDLINE]Related articles

SREBP1 is required for the induction by glucose of pancreatic beta-cell genes involved in glucose sensing.

Diraison F, Ravier MA, Richards SK, Smith RM, Shimano H, Rutter GA.

J Lipid Res. 2008 Apr;49(4):814-22. Epub 2008 Jan 4.PMID: 18178930 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of AMP-activated protein kinase protects pancreatic beta-cells from cytokine-mediated apoptosis and CD8+ T-cell-induced cytotoxicity.

Riboulet-Chavey A, Diraison F, Siew LK, Wong FS, Rutter GA.

Diabetes. 2008 Feb;57(2):415-23. Epub 2007 Nov 14.PMID: 18003756 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP depletion inhibits Ca2+ release, influx and extrusion in pancreatic acinar cells but not pathological Ca2+ responses induced by bile.

Barrow SL, Voronina SG, da Silva Xavier G, Chvanov MA, Longbottom RE, Gerasimenko OV, Petersen OH, Rutter GA, Tepikin AV.

Pflugers Arch. 2008 Mar;455(6):1025-39. Epub 2007 Oct 20.PMID: 17952455 [PubMed - indexed for MEDLINE]Related articles

Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress.

Zatyka M, Ricketts C, da Silva Xavier G, Minton J, Fenton S, Hofmann-Thiel S, Rutter GA, Barrett TG.

Hum Mol Genet. 2008 Jan 15;17(2):190-200. Epub 2007 Oct 18.PMID: 17947299 [PubMed - indexed for MEDLINE]Related articlesFree article

Generating new candidate genes for neonatal diabetes: functional and genetic studies of insulin secretion in type 2 diabetes.

Rutter GA.

Endocr Dev. 2007;12:75-85. Review.PMID: 17923771 [PubMed - indexed for MEDLINE]Related articles

The relationship between p38 mitogen-activated protein kinase and AMP-activated protein kinase during myocardial ischemia.

Jacquet S, Zarrinpashneh E, Chavey A, Ginion A, Leclerc I, Viollet B, Rutter GA, Bertrand L, Marber MS.

Cardiovasc Res. 2007 Dec 1;76(3):465-72. Epub 2007 Aug 8.PMID: 17765884 [PubMed - indexed for MEDLINE]Related articlesFree article

Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells.

Otonkoski T, Jiao H, Kaminen-Ahola N, Tapia-Paez I, Ullah MS, Parton LE, Schuit F, Quintens R, Sipilä I, Mayatepek E, Meissner T, Halestrap AP, Rutter GA, Kere J.

Am J Hum Genet. 2007 Sep;81(3):467-74. Epub 2007 Jul 26.PMID: 17701893 [PubMed - indexed for MEDLINE]Related articlesFree article

MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines.

Baroukh N, Ravier MA, Loder MK, Hill EV, Bounacer A, Scharfmann R, Rutter GA, Van Obberghen E.

J Biol Chem. 2007 Jul 6;282(27):19575-88. Epub 2007 Apr 26.PMID: 17462994 [PubMed - indexed for MEDLINE]Related articlesFree article

Luciferase expression for ATP imaging: application to cardiac myocytes.

Bell CJ, Manfredi G, Griffiths EJ, Rutter GA.

Methods Cell Biol. 2007;80:341-52. Review. No abstract available. PMID: 17445703 [PubMed - indexed for MEDLINE]Related articles

Glucose is necessary for embryonic pancreatic endocrine cell differentiation.

Guillemain G, Filhoulaud G, Da Silva-Xavier G, Rutter GA, Scharfmann R.

J Biol Chem. 2007 May 18;282(20):15228-37. Epub 2007 Mar 21.PMID: 17376780 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-dependent regulation of gamma-aminobutyric acid (GABA A) receptor expression in mouse pancreatic islet alpha-cells.

Bailey SJ, Ravier MA, Rutter GA.

Diabetes. 2007 Feb;56(2):320-7.PMID: 17259375 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose sensing by hypothalamic neurones and pancreatic islet cells: AMPle evidence for common mechanisms?

Mountjoy PD, Rutter GA.

Exp Physiol. 2007 Mar;92(2):311-9. Epub 2006 Dec 7. Review.PMID: 17158178 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity.

Mountjoy PD, Bailey SJ, Rutter GA.

Diabetologia. 2007 Jan;50(1):168-77. Epub 2006 Nov 9.PMID: 17093945 [PubMed - indexed for MEDLINE]Related articles

FoxO1 is required for the regulation of preproglucagon gene expression by insulin in pancreatic alphaTC1-9 cells.

McKinnon CM, Ravier MA, Rutter GA.

J Biol Chem. 2006 Dec 22;281(51):39358-69. Epub 2006 Oct 24.PMID: 17062568 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic beta-cells.

An R, da Silva Xavier G, Hao HX, Semplici F, Rutter J, Rutter GA.

Biochem Soc Trans. 2006 Nov;34(Pt 5):791-3.PMID: 17052199 [PubMed - indexed for MEDLINE]Related articles

Rapid three-dimensional imaging of individual insulin release events by Nipkow disc confocal microscopy.

Rutter GA, Loder MK, Ravier MA.

Biochem Soc Trans. 2006 Nov;34(Pt 5):675-8.PMID: 17052172 [PubMed - indexed for MEDLINE]Related articles

Ca2+ microdomains and the control of insulin secretion.

Rutter GA, Tsuboi T, Ravier MA.

Cell Calcium. 2006 Nov-Dec;40(5-6):539-51. Epub 2006 Oct 9. Review.PMID: 17030367 [PubMed - indexed for MEDLINE]Related articles

Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver.

Rencurel F, Foretz M, Kaufmann MR, Stroka D, Looser R, Leclerc I, da Silva Xavier G, Rutter GA, Viollet B, Meyer UA.

Mol Pharmacol. 2006 Dec;70(6):1925-34. Epub 2006 Sep 20.PMID: 16988011 [PubMed - indexed for MEDLINE]Related articlesFree article

ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic beta-cells.

da Silva Xavier G, Rutter GA, Diraison F, Andreolas C, Leclerc I.

J Lipid Res. 2006 Nov;47(11):2482-91. Epub 2006 Aug 4.PMID: 16891625 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP regulation in adult rat cardiomyocytes: time-resolved decoding of rapid mitochondrial calcium spiking imaged with targeted photoproteins.

Bell CJ, Bright NA, Rutter GA, Griffiths EJ.

J Biol Chem. 2006 Sep 22;281(38):28058-67. Epub 2006 Jul 31.PMID: 16882672 [PubMed - indexed for MEDLINE]Related articlesFree article

Variance stabilization and normalization for one-color microarray data using a data-driven multiscale approach.

Motakis ES, Nason GP, Fryzlewicz P, Rutter GA.

Bioinformatics. 2006 Oct 15;22(20):2547-53. Epub 2006 Jul 28.PMID: 16877753 [PubMed - indexed for MEDLINE]Related articlesFree article

Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis.

Parton LE, McMillen PJ, Shen Y, Docherty E, Sharpe E, Diraison F, Briscoe CP, Rutter GA.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E982-94. Epub 2006 Jun 13.PMID: 16772326 [PubMed - indexed for MEDLINE]Related articlesFree article

Expanding role of AMPK in endocrinology.

Kola B, Boscaro M, Rutter GA, Grossman AB, Korbonits M.

Trends Endocrinol Metab. 2006 Jul;17(5):205-15. Review.PMID: 16766204 [PubMed - indexed for MEDLINE]Related articles

Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis.

Varadi A, Grant A, McCormack M, Nicolson T, Magistri M, Mitchell KJ, Halestrap AP, Yuan H, Schwappach B, Rutter GA.

Diabetologia. 2006 Jul;49(7):1567-77. Epub 2006 May 12.PMID: 16752175 [PubMed - indexed for MEDLINE]Related articles

Insulin vesicle release: walk, kiss, pause ... then run.

Rutter GA, Hill EV.

Physiology (Bethesda). 2006 Jun;21:189-96. Review.PMID: 16714477 [PubMed - indexed for MEDLINE]Related articles

Moving Ca2+ from the endoplasmic reticulum to mitochondria: is spatial intimacy enough?

Rutter GA.

Biochem Soc Trans. 2006 Jun;34(Pt 3):351-5. Review.PMID: 16709159 [PubMed - indexed for MEDLINE]Related articles

Sustained exposure to high glucose concentrations modifies glucose signaling and the mechanics of secretory vesicle fusion in primary rat pancreatic beta-cells.

Tsuboi T, Ravier MA, Parton LE, Rutter GA.

Diabetes. 2006 Apr;55(4):1057-65.PMID: 16567529 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin secretion in health and disease: genomics, proteomics and single vesicle dynamics.

Rutter GA, Varadi A, Tsuboi T, Parton L, Ravier M.

Biochem Soc Trans. 2006 Apr;34(Pt 2):247-50. Review.PMID: 16545086 [PubMed - indexed for MEDLINE]Related articles

Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors.

Storto M, Capobianco L, Battaglia G, Molinaro G, Gradini R, Riozzi B, Di Mambro A, Mitchell KJ, Bruno V, Vairetti MP, Rutter GA, Nicoletti F.

Mol Pharmacol. 2006 Apr;69(4):1234-41. Epub 2006 Jan 19.PMID: 16424079 [PubMed - indexed for MEDLINE]Related articlesFree article

Over-expression of AMP-activated protein kinase impairs pancreatic {beta}-cell function in vivo.

Richards SK, Parton LE, Leclerc I, Rutter GA, Smith RM.

J Endocrinol. 2005 Nov;187(2):225-35.PMID: 16293770 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells.

Ravier MA, Rutter GA.

Diabetes. 2005 Jun;54(6):1789-97.PMID: 15919801 [PubMed - indexed for MEDLINE]Related articlesFree article

Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis.

Tsuboi T, Ravier MA, Xie H, Ewart MA, Gould GW, Baldwin SA, Rutter GA.

J Biol Chem. 2005 Jul 8;280(27):25565-70. Epub 2005 May 3.PMID: 15878854 [PubMed - indexed for MEDLINE]Related articlesFree article

Metformin prevents glucose-induced protein kinase C-beta2 activation in human umbilical vein endothelial cells through an antioxidant mechanism.

Gallo A, Ceolotto G, Pinton P, Iori E, Murphy E, Rutter GA, Rizzuto R, Semplicini A, Avogaro A.

Diabetes. 2005 Apr;54(4):1123-31.PMID: 15793252 [PubMed - indexed for MEDLINE]Related articlesFree article

Myosin Va transports dense core secretory vesicles in pancreatic MIN6 beta-cells.

Varadi A, Tsuboi T, Rutter GA.

Mol Biol Cell. 2005 Jun;16(6):2670-80. Epub 2005 Mar 23.PMID: 15788565 [PubMed - indexed for MEDLINE]Related articlesFree article