PubMed

Ventromedial hypothalamic nitric oxide production is necessary for hypoglycemia detection and counter-regulation.

Fioramonti X, Marsollier N, Song Z, Fakira KA, Patel RM, Brown S, Duparc T, Pica-Mendez A, Sanders NM, Knauf C, Valet P, McCrimmon RJ, Beuve A, Magnan C, Routh VH.

Diabetes. 2009 Nov 23. [Epub ahead of print]PMID: 19934009 [PubMed - as supplied by publisher]Related articles

Motor unit number estimate as a predictor of motor dysfunction in an animal model of type 1 diabetes.

Souayah N, Potian JG, Garcia CC, Krivitskaya N, Boone C, Routh VH, McArdle JJ.

Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E602-8. Epub 2009 Jul 14.PMID: 19602580 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons.

Murphy BA, Fakira KA, Song Z, Beuve A, Routh VH.

Am J Physiol Cell Physiol. 2009 Sep;297(3):C750-8. Epub 2009 Jul 1.PMID: 19570894 [PubMed - indexed for MEDLINE]Related articles

Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose.

Cotero VE, Routh VH.

Am J Physiol Endocrinol Metab. 2009 May;296(5):E1101-9. Epub 2009 Feb 17. Erratum in: Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E560-1. PMID: 19223652 [PubMed - indexed for MEDLINE]Related articles

Fasting enhances the response of arcuate neuropeptide Y-glucose-inhibited neurons to decreased extracellular glucose.

Murphy BA, Fioramonti X, Jochnowitz N, Fakira K, Gagen K, Contie S, Lorsignol A, Penicaud L, Martin WJ, Routh VH.

Am J Physiol Cell Physiol. 2009 Apr;296(4):C746-56. Epub 2009 Feb 11.PMID: 19211911 [PubMed - indexed for MEDLINE]Related articles

Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons.

Kang L, Sanders NM, Dunn-Meynell AA, Gaspers LD, Routh VH, Thomas AP, Levin BE.

Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R784-92. Epub 2007 Dec 19.PMID: 18094065 [PubMed - indexed for MEDLINE]Related articles

Hyperglycemia impairs glucose and insulin regulation of nitric oxide production in glucose-inhibited neurons in the ventromedial hypothalamus.

Canabal DD, Potian JG, Duran RG, McArdle JJ, Routh VH.

Am J Physiol Regul Integr Comp Physiol. 2007 Aug;293(2):R592-600. Epub 2007 May 30.PMID: 17537841 [PubMed - indexed for MEDLINE]Related articles

Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opio melanocortin networks?

Fioramonti X, Contié S, Song Z, Routh VH, Lorsignol A, Pénicaud L.

Diabetes. 2007 May;56(5):1219-27. Epub 2007 Jan 29.PMID: 17261674 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose, insulin, and leptin signaling pathways modulate nitric oxide synthesis in glucose-inhibited neurons in the ventromedial hypothalamus.

Canabal DD, Song Z, Potian JG, Beuve A, McArdle JJ, Routh VH.

Am J Physiol Regul Integr Comp Physiol. 2007 Apr;292(4):R1418-28. Epub 2006 Dec 14.PMID: 17170237 [PubMed - indexed for MEDLINE]Related articles

Recurrent hypoglycemia reduces the glucose sensitivity of glucose-inhibited neurons in the ventromedial hypothalamus nucleus.

Song Z, Routh VH.

Am J Physiol Regul Integr Comp Physiol. 2006 Nov;291(5):R1283-7. Epub 2006 Jun 22.PMID: 16793940 [PubMed - indexed for MEDLINE]Related articles

Corticotrophin-releasing factor receptors within the ventromedial hypothalamus regulate hypoglycemia-induced hormonal counterregulation.

McCrimmon RJ, Song Z, Cheng H, McNay EC, Weikart-Yeckel C, Fan X, Routh VH, Sherwin RS.

J Clin Invest. 2006 Jun;116(6):1723-30.PMID: 16741581 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing.

Kang L, Dunn-Meynell AA, Routh VH, Gaspers LD, Nagata Y, Nishimura T, Eiki J, Zhang BB, Levin BE.

Diabetes. 2006 Feb;55(2):412-20. Erratum in: Diabetes. 2006 Mar;55(3):862. PMID: 16443775 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of oleic acid on distinct populations of neurons in the hypothalamic arcuate nucleus are dependent on extracellular glucose levels.

Wang R, Cruciani-Guglielmacci C, Migrenne S, Magnan C, Cotero VE, Routh VH.

J Neurophysiol. 2006 Mar;95(3):1491-8. Epub 2005 Nov 23.PMID: 16306178 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus.

Song Z, Routh VH.

Diabetes. 2005 Jan;54(1):15-22.PMID: 15616006 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuronal glucosensing: what do we know after 50 years?

Levin BE, Routh VH, Kang L, Sanders NM, Dunn-Meynell AA.

Diabetes. 2004 Oct;53(10):2521-8. Review.PMID: 15448079 [PubMed - indexed for MEDLINE]Related articlesFree article

The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides.

Wang R, Liu X, Hentges ST, Dunn-Meynell AA, Levin BE, Wang W, Routh VH.

Diabetes. 2004 Aug;53(8):1959-65.PMID: 15277373 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of glucosensing neurons in the detection of hypoglycemia.

Routh VH, Song Z, Liu X.

Diabetes Technol Ther. 2004 Jun;6(3):413-21. Review.PMID: 15198847 [PubMed - indexed for MEDLINE]Related articles

Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons.

Kang L, Routh VH, Kuzhikandathil EV, Gaspers LD, Levin BE.

Diabetes. 2004 Mar;53(3):549-59.PMID: 14988237 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucosensing neurons in the ventromedial hypothalamic nucleus (VMN) and hypoglycemia-associated autonomic failure (HAAF).

Routh VH.

Diabetes Metab Res Rev. 2003 Sep-Oct;19(5):348-56. Review.PMID: 12951642 [PubMed - indexed for MEDLINE]Related articles

CNS sensing and regulation of peripheral glucose levels.

Levin BE, Dunn-Meynell AA, Routh VH.

Int Rev Neurobiol. 2002;51:219-58. Review.PMID: 12420361 [PubMed - indexed for MEDLINE]Related articles

Glucose-sensing neurons: are they physiologically relevant?

Routh VH.

Physiol Behav. 2002 Jul;76(3):403-13. Review.PMID: 12117577 [PubMed - indexed for MEDLINE]Related articles

Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons.

Dunn-Meynell AA, Routh VH, Kang L, Gaspers L, Levin BE.

Diabetes. 2002 Jul;51(7):2056-65.PMID: 12086933 [PubMed - indexed for MEDLINE]Related articlesFree article

Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus.

Song Z, Levin BE, McArdle JJ, Bakhos N, Routh VH.

Diabetes. 2001 Dec;50(12):2673-81.PMID: 11723049 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain glucosensing and the K(ATP) channel.

Levin BE, Dunn-Meynell AA, Routh VH.

Nat Neurosci. 2001 May;4(5):459-60. No abstract available. PMID: 11319550 [PubMed - indexed for MEDLINE]Related articles

Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats.

Spanswick D, Smith MA, Mirshamsi S, Routh VH, Ashford ML.

Nat Neurosci. 2000 Aug;3(8):757-8.PMID: 10903566 [PubMed - indexed for MEDLINE]Related articles

Brain glucose sensing and body energy homeostasis: role in obesity and diabetes.

Levin BE, Dunn-Meynell AA, Routh VH.

Am J Physiol. 1999 May;276(5 Pt 2):R1223-31. Review.PMID: 10233011 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiposity and serum leptin increase in fatty (fa/fa) BNZ neonates without decreased VMH serotonergic activity.

Horwitz BA, Hamilton JS, Routh VH, Green K, Havel P, Chan A.

Am J Physiol. 1998 Jun;274(6 Pt 1):E1009-17.PMID: 9611150 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation modulates the activity of the ATP-sensitive K+ channel in the ventromedial hypothalamic nucleus.

Routh VH, McArdle JJ, Levin BE.

Brain Res. 1997 Dec 5;778(1):107-19.PMID: 9462882 [PubMed - indexed for MEDLINE]Related articles

A novel technique for producing antibody-coated microprobes using a thiol-terminal silane and a heterobifunctional crosslinker.

Routh VH, Helke CJ.

J Neurosci Methods. 1997 Feb;71(2):163-8.PMID: 9128151 [PubMed - indexed for MEDLINE]Related articles

Low-affinity sulfonylurea binding sites reside on neuronal cell bodies in the brain.

Dunn-Meynell AA, Routh VH, McArdle JJ, Levin BE.

Brain Res. 1997 Jan 16;745(1-2):1-9.PMID: 9037388 [PubMed - indexed for MEDLINE]Related articles

Role of the brain in energy balance and obesity.

Levin BE, Routh VH.

Am J Physiol. 1996 Sep;271(3 Pt 2):R491-500. Review.PMID: 8853368 [PubMed - indexed for MEDLINE]Related articles

Adrenalectomy increases serotonin turnover in brains of obese Zucker rats.

Routh VH, Stern JS, Horwitz BA.

Physiol Behav. 1995 Sep;58(3):491-9.PMID: 8587957 [PubMed - indexed for MEDLINE]Related articles

Tachykinin receptors in the spinal cord.

Routh VH, Helke CJ.

Prog Brain Res. 1995;104:93-108. Review.PMID: 8552786 [PubMed - indexed for MEDLINE]Related articles

Serotonergic activity is depressed in the ventromedial hypothalamic nucleus of 12-day-old obese Zucker rats.

Routh VH, Stern JS, Horwitz BA.

Am J Physiol. 1994 Sep;267(3 Pt 2):R712-9.PMID: 7522410 [PubMed - indexed for MEDLINE]Related articles

Hypothalamic monoaminergic activity in 11-week-old cold-exposed female lean (Fa/Fa) and obese (fa/fa) Zucker rats.

Routh VH, Horwitz BA, Gietzen DW, Stern JS.

Obes Res. 1994 Jan;2(1):28-37.PMID: 16355483 [PubMed - indexed for MEDLINE]Related articles

Altered alpha 1-adrenoceptor binding in intact and adrenalectomized obese Zucker rats (fa/fa).

Levin BE, Planas B, Routh VH, Hamilton J, Stern JS, Horwitz BA.

Brain Res. 1993 Jun 18;614(1-2):146-54.PMID: 8394183 [PubMed - indexed for MEDLINE]Related articles

Litter size, adrenalectomy and high fat diet alter hypothalamic monoamines in genetically lean (Fa/Fa) Zucker rats.

Routh VH, Hamilton JS, Stern JS, Horwitz BA.

J Nutr. 1993 Jan;123(1):74-84.PMID: 8421233 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuronal activity in hypothalamic nuclei of obese and lean Zucker rats.

Routh VH, Murakami DM, Stern JS, Fuller CA, Horwitz BA.

Int J Obes. 1990 Oct;14(10):879-91.PMID: 2176650 [PubMed - indexed for MEDLINE]Related articles