PubMed

Evidence that facilitative glucose transporters may fold as beta-barrels.

Fischbarg J, Cheung M, Czegledy F, Li J, Iserovich P, Kuang K, Hubbard J, Garner M, Rosen OM, Golde DW, et al.

Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11658-62.PMID: 8265604 [PubMed - indexed for MEDLINE]Related articlesFree article

Human insulin receptor mutated at threonine 1336 functions normally in Chinese hamster ovary cells.

Ahn J, Rosen OM, Donner DB.

J Biol Chem. 1993 Aug 5;268(22):16839-44.PMID: 8393875 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of the human insulin receptor tyrosine kinase from the baculovirus expression system with protein kinase C in a cell-free system.

Ahn J, Donner DB, Rosen OM.

J Biol Chem. 1993 Apr 5;268(10):7571-6.PMID: 8463287 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of insulin receptor autophosphorylation in signal transduction.

Murakami MS, Rosen OM.

J Biol Chem. 1991 Nov 25;266(33):22653-60.PMID: 1658004 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of the insulin receptor by a casein kinase I-like enzyme.

Rapuano M, Rosen OM.

J Biol Chem. 1991 Jul 15;266(20):12902-7.PMID: 1649167 [PubMed - indexed for MEDLINE]Related articlesFree article

A possible role for a mammalian facilitative hexose transporter in the development of resistance to drugs.

Vera JC, Castillo GR, Rosen OM.

Mol Cell Biol. 1991 Jul;11(7):3407-18.PMID: 1675425 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain fatty acyl coenzyme A.

Majumdar S, Rossi MW, Fujiki T, Phillips WA, Disa S, Queen CF, Johnston RB Jr, Rosen OM, Corkey BE, Korchak HM.

J Biol Chem. 1991 May 15;266(14):9285-94.PMID: 2026625 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of inducible membrane-anchored insulin receptor kinase enhances deoxyglucose uptake.

Lebwohl DE, Nunez I, Chan M, Rosen OM.

J Biol Chem. 1991 Jan 5;266(1):386-90.PMID: 1845969 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional expression of murine multidrug resistance in Xenopus laevis oocytes.

Castillo G, Vera JC, Yang CP, Horwitz SB, Rosen OM.

Proc Natl Acad Sci U S A. 1990 Jun;87(12):4737-41.PMID: 1693776 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose transporters serve as water channels.

Fischbarg J, Kuang KY, Vera JC, Arant S, Silverstein SC, Loike J, Rosen OM.

Proc Natl Acad Sci U S A. 1990 Apr;87(8):3244-7.PMID: 2326282 [PubMed - indexed for MEDLINE]Related articlesFree article

Mn2(+)-binding properties of a recombinant protein-tyrosine kinase derived from the human insulin receptor.

Wente SR, Villalba M, Schramm VL, Rosen OM.

Proc Natl Acad Sci U S A. 1990 Apr;87(7):2805-9.PMID: 2157215 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-receptor approaches to studying protein kinase domain.

Wente SR, Rosen OM.

Diabetes Care. 1990 Mar;13(3):280-7. Review.PMID: 2155093 [PubMed - indexed for MEDLINE]Related articles

Reconstitution of an insulin signaling pathway in Xenopus laevis oocytes: coexpression of a mammalian insulin receptor and three different mammalian hexose transporters.

Vera JC, Rosen OM.

Mol Cell Biol. 1990 Feb;10(2):743-51.PMID: 1688999 [PubMed - indexed for MEDLINE]Related articlesFree article

Hydrolysis of glycosyl-phosphatidylinositol in response to insulin is reduced in cells bearing kinase-deficient insulin receptors.

Villalba M, Alvarez JF, Russell DS, Mato JM, Rosen OM.

Growth Factors. 1990;2(2-3):91-7.PMID: 2160261 [PubMed - indexed for MEDLINE]Related articles

Banting lecture 1989. Structure and function of insulin receptors.

Rosen OM.

Diabetes. 1989 Dec;38(12):1508-11. Review.PMID: 2555239 [PubMed - indexed for MEDLINE]Related articles

Another version of the human insulin receptor kinase domain: expression, purification, and characterization.

Villalba M, Wente SR, Russell DS, Ahn JC, Reichelderfer CF, Rosen OM.

Proc Natl Acad Sci U S A. 1989 Oct;86(20):7848-52.PMID: 2554291 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional expression of mammalian glucose transporters in Xenopus laevis oocytes: evidence for cell-dependent insulin sensitivity.

Vera JC, Rosen OM.

Mol Cell Biol. 1989 Oct;9(10):4187-95.PMID: 2479821 [PubMed - indexed for MEDLINE]Related articlesFree article

Complete activation of protein kinase C by an antipeptide antibody directed against the pseudosubstrate prototope.

Makowske M, Rosen OM.

J Biol Chem. 1989 Sep 25;264(27):16155-9.PMID: 2777783 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits.

Garofalo RS, Rosen OM.

Mol Cell Biol. 1989 Jul;9(7):2806-17.PMID: 2476658 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth factors rapidly induce expression of the glucose transporter gene.

Hiraki Y, Rosen OM, Birnbaum MJ.

J Biol Chem. 1988 Sep 25;263(27):13655-62.PMID: 3262104 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure, biosynthesis, and function of the hexose transporter in Chinese hamster ovary cells deficient in N-acetylglucosaminyltransferase 1 activity.

Haspel HC, Revillame J, Rosen OM.

J Cell Physiol. 1988 Aug;136(2):361-6.PMID: 2970467 [PubMed - indexed for MEDLINE]Related articles

Polylysine activates and alters the divalent cation requirements of the insulin receptor protein tyrosine kinase.

Rosen OM, Lebwohl DE.

FEBS Lett. 1988 Apr 25;231(2):397-401.PMID: 3360145 [PubMed - indexed for MEDLINE]Related articles

Synthesis, purification, and characterization of the cytoplasmic domain of the human insulin receptor using a baculovirus expression system.

Herrera R, Lebwohl D, Garcia de Herreros A, Kallen RG, Rosen OM.

J Biol Chem. 1988 Apr 25;263(12):5560-8.PMID: 2451671 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue localization of Drosophila melanogaster insulin receptor transcripts during development.

Garofalo RS, Rosen OM.

Mol Cell Biol. 1988 Apr;8(4):1638-47.PMID: 2454394 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid.

Makowske M, Ballester R, Cayre Y, Rosen OM.

J Biol Chem. 1988 Mar 5;263(7):3402-10.PMID: 3422643 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of antisera to a synthetic carboxyl-terminal peptide of the glucose transporter protein.

Haspel HC, Rosenfeld MG, Rosen OM.

J Biol Chem. 1988 Jan 5;263(1):398-403.PMID: 3335504 [PubMed - indexed for MEDLINE]Related articlesFree article

Reevaluation of the evidence that an antibody to the insulin receptor is insulinmimetic without activating the protein tyrosine kinase activity of the receptor.

Gherzi R, Russell DS, Taylor SI, Rosen OM.

J Biol Chem. 1987 Dec 15;262(35):16900-5.PMID: 3680277 [PubMed - indexed for MEDLINE]Related articlesFree article

After insulin binds.

Rosen OM.

Science. 1987 Sep 18;237(4821):1452-8. Review.PMID: 2442814 [PubMed - indexed for MEDLINE]Related articles

Purification of a phosphoinositide-specific phospholipase C from bovine brain.

Rebecchi MJ, Rosen OM.

J Biol Chem. 1987 Sep 15;262(26):12526-32.PMID: 3040754 [PubMed - indexed for MEDLINE]Related articlesFree article

The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation.

Russell DS, Gherzi R, Johnson EL, Chou CK, Rosen OM.

J Biol Chem. 1987 Aug 25;262(24):11833-40.PMID: 2957374 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure and ligand specificity of the Drosophila melanogaster insulin receptor.

Fernandez-Almonacid R, Rosen OM.

Mol Cell Biol. 1987 Aug;7(8):2718-27.PMID: 3118188 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of polyphosphoinositide hydrolysis by thrombin in membranes from human fibroblasts.

Rebecchi MJ, Rosen OM.

Biochem J. 1987 Jul 1;245(1):49-57.PMID: 2822018 [PubMed - indexed for MEDLINE]Related articlesFree article

Purification of a bovine liver S6 kinase.

Tabarini D, Garcia de Herreros A, Heinrich J, Rosen OM.

Biochem Biophys Res Commun. 1987 Apr 29;144(2):891-9.PMID: 3579946 [PubMed - indexed for MEDLINE]Related articles

Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription.

Birnbaum MJ, Haspel HC, Rosen OM.

Science. 1987 Mar 20;235(4795):1495-8.PMID: 3029870 [PubMed - indexed for MEDLINE]Related articles

Phorbol ester- and protein kinase C-mediated phosphorylation of the cellular Kirsten ras gene product.

Ballester R, Furth ME, Rosen OM.

J Biol Chem. 1987 Feb 25;262(6):2688-95.PMID: 3546293 [PubMed - indexed for MEDLINE]Related articlesFree article

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.

Chou CK, Dull TJ, Russell DS, Gherzi R, Lebwohl D, Ullrich A, Rosen OM.

J Biol Chem. 1987 Feb 5;262(4):1842-7.PMID: 3100537 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunoassay and immunopurification of macrophage calmodulin-binding protein.

Orlow SJ, Rosen OM.

Methods Enzymol. 1987;139:148-56. No abstract available. PMID: 3587021 [PubMed - indexed for MEDLINE]Related articles

Regulation of the protein kinase activity of the human insulin receptor.

Herrera R, Rosen OM.

J Recept Res. 1987;7(1-4):405-15.PMID: 3040980 [PubMed - indexed for MEDLINE]Related articles

A cDNA encoding protein kinase C identifies two species of mRNA in brain and GH3 cells.

Makowske M, Birnbaum MJ, Ballester R, Rosen OM.

J Biol Chem. 1986 Oct 15;261(29):13389-92.PMID: 3093480 [PubMed - indexed for MEDLINE]Related articlesFree article

Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation.

Herrera R, Rosen OM.

J Biol Chem. 1986 Sep 15;261(26):11980-5.PMID: 3745176 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein.

Birnbaum MJ, Haspel HC, Rosen OM.

Proc Natl Acad Sci U S A. 1986 Aug;83(16):5784-8.PMID: 3016720 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of synthetic insulin receptor peptides by the insulin receptor kinase and evidence that the preferred sequence containing Tyr-1150 is phosphorylated in vivo.

Stadtmauer L, Rosen OM.

J Biol Chem. 1986 Jul 25;261(21):10000-5.PMID: 3733682 [PubMed - indexed for MEDLINE]Related articlesFree article

Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody.

Petruzzelli L, Herrera R, Arenas-Garcia R, Fernandez R, Birnbaum MJ, Rosen OM.

Proc Natl Acad Sci U S A. 1986 Jul;83(13):4710-4.PMID: 3014506 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose deprivation and hexose transporter polypeptides of murine fibroblasts.

Haspel HC, Wilk EW, Birnbaum MJ, Cushman SW, Rosen OM.

J Biol Chem. 1986 May 25;261(15):6778-89.PMID: 3700414 [PubMed - indexed for MEDLINE]Related articlesFree article

Increasing the cAMP content of IM-9 cells alters the phosphorylation state and protein kinase activity of the insulin receptor.

Stadtmauer L, Rosen OM.

J Biol Chem. 1986 Mar 5;261(7):3402-7.PMID: 2419331 [PubMed - indexed for MEDLINE]Related articlesFree article

Antibodies to deduced sequences of the insulin receptor distinguish conserved and nonconserved regions in the IGF-I receptor.

Herrera R, Petruzzelli LM, Rosen OM.

J Biol Chem. 1986 Feb 25;261(6):2489-91.PMID: 3753971 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin receptor as a tyrosine protein kinase.

Rosen OM.

Ann N Y Acad Sci. 1986;463:13-9. No abstract available. PMID: 3521434 [PubMed - indexed for MEDLINE]Related articles

Protein tyrosine kinases, protein serine kinases, and the mechanism of action of insulin.

Rosen OM.

Harvey Lect. 1986-1987;82:105-22. Review. No abstract available. PMID: 2966136 [PubMed - indexed for MEDLINE]Related articles

Acquisition of insulin-dependent protein tyrosine kinase activity during Drosophila embryogenesis.

Petruzzelli L, Herrera R, Garcia-Arenas R, Rosen OM.

J Biol Chem. 1985 Dec 25;260(30):16072-5.PMID: 3934169 [PubMed - indexed for MEDLINE]Related articlesFree article

Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate.

Ballester R, Rosen OM.

J Biol Chem. 1985 Dec 5;260(28):15194-9.PMID: 3905792 [PubMed - indexed for MEDLINE]Related articlesFree article