PubMed

IFATS collection: Adipose stromal cell differentiation is reduced by endothelial cell contact and paracrine communication: role of canonical Wnt signaling.

Rajashekhar G, Traktuev DO, Roell WC, Johnstone BH, Merfeld-Clauss S, Van Natta B, Rosen ED, March KL, Clauss M.

Stem Cells. 2008 Oct;26(10):2674-81. Epub 2008 Jul 31.PMID: 18669909 [PubMed - indexed for MEDLINE]Related articlesFree article

Identifying and genotyping transgene integration loci.

Liang Z, Breman AM, Grimes BR, Rosen ED.

Transgenic Res. 2008 Oct;17(5):979-83. Epub 2008 Jul 9.PMID: 18612840 [PubMed - indexed for MEDLINE]Related articles

Rat prostate tumors express cancer procoagulant, an activator of coagulation factor X.

Kamocka M, Pollard M, Suckow M, Mielicki WP, Rosen ED.

Comp Med. 2008 Jun;58(3):282-6.PMID: 18589871 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue vaccines for cancer.

Suckow MA, Heinrich J, Rosen ED.

Expert Rev Vaccines. 2007 Dec;6(6):925-37. Review.PMID: 18377356 [PubMed - indexed for MEDLINE]Related articles

The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis.

Xu Z, Yu S, Hsu CH, Eguchi J, Rosen ED.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2421-6. Epub 2008 Feb 4.PMID: 18250317 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon regulatory factors are transcriptional regulators of adipogenesis.

Eguchi J, Yan QW, Schones DE, Kamal M, Hsu CH, Zhang MQ, Crawford GE, Rosen ED.

Cell Metab. 2008 Jan;7(1):86-94.PMID: 18177728 [PubMed - indexed for MEDLINE]Related articlesFree article

A multiscale model of thrombus development.

Xu Z, Chen N, Kamocka MM, Rosen ED, Alber M.

J R Soc Interface. 2008 Jul 6;5(24):705-22.PMID: 17925274 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization.

Cai L, Johnstone BH, Cook TG, Liang Z, Traktuev D, Cornetta K, Ingram DA, Rosen ED, March KL.

Stem Cells. 2007 Dec;25(12):3234-43. Epub 2007 Sep 27.PMID: 17901400 [PubMed - indexed for MEDLINE]Related articlesFree article

The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance.

Yan QW, Yang Q, Mody N, Graham TE, Hsu CH, Xu Z, Houstis NE, Kahn BB, Rosen ED.

Diabetes. 2007 Oct;56(10):2533-40. Epub 2007 Jul 16.PMID: 17639021 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of human PC-346C prostate cancer growth in mice by a xenogeneic tissue vaccine.

Suckow MA, Rosen ED, Wolter WR, Sailes V, Jeffrey R, Tenniswood M.

Cancer Immunol Immunother. 2007 Aug;56(8):1275-83. Epub 2007 Jan 23.PMID: 17242926 [PubMed - indexed for MEDLINE]Related articles

FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults.

Mukherjee A, Sidis Y, Mahan A, Raher MJ, Xia Y, Rosen ED, Bloch KD, Thomas MK, Schneyer AL.

Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1348-53. Epub 2007 Jan 17.PMID: 17229845 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipocytes as regulators of energy balance and glucose homeostasis.

Rosen ED, Spiegelman BM.

Nature. 2006 Dec 14;444(7121):847-53. Review.PMID: 17167472 [PubMed - indexed for MEDLINE]Related articles

Adipocyte differentiation from the inside out.

Rosen ED, MacDougald OA.

Nat Rev Mol Cell Biol. 2006 Dec;7(12):885-96. Review.PMID: 17139329 [PubMed - indexed for MEDLINE]Related articles

Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade.

Jimenez MA, Akerblad P, Sigvardsson M, Rosen ED.

Mol Cell Biol. 2007 Jan;27(2):743-57. Epub 2006 Oct 23.PMID: 17060461 [PubMed - indexed for MEDLINE]Related articlesFree article

Vaccination against prostate cancer using a live tissue factor deficient cell line in Lobund-Wistar rats.

Heinrich JE, Pollard M, Wolter WA, Liang Z, Song H, Rosen ED, Suckow MA.

Cancer Immunol Immunother. 2007 May;56(5):725-30. Epub 2006 Sep 5.PMID: 16953436 [PubMed - indexed for MEDLINE]Related articles

Reactive oxygen species have a causal role in multiple forms of insulin resistance.

Houstis N, Rosen ED, Lander ES.

Nature. 2006 Apr 13;440(7086):944-8.PMID: 16612386 [PubMed - indexed for MEDLINE]Related articles

Searching for hemostatic modifier genes affecting the phenotype of mice with very low levels of FVII.

Rosen ED, Xuei X, Suckow M, Edenberg H.

Blood Cells Mol Dis. 2006 Mar-Apr;36(2):131-4. Epub 2006 Mar 9.PMID: 16524747 [PubMed - indexed for MEDLINE]Related articles

New drugs from fat bugs?

Rosen ED.

Cell Metab. 2006 Jan;3(1):1-2.PMID: 16399497 [PubMed - indexed for MEDLINE]Related articles

Tissue distribution of fetal liver cells following in utero transplantation in mice.

Suckow MA, Zollman A, Cornelissen I, Casad M, Roahrig J, Castellino FJ, Rosen ED.

Exp Biol Med (Maywood). 2005 Dec;230(11):860-4.PMID: 16339751 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation of genetically-altered mice producing very low levels of coagulation factorVII.

Rosen ED, Xu H, Liang Z, Martin JA, Suckow M, Castellino FJ.

Thromb Haemost. 2005 Sep;94(3):493-7.PMID: 16268461 [PubMed - indexed for MEDLINE]Related articles

The transcriptional basis of adipocyte development.

Rosen ED.

Prostaglandins Leukot Essent Fatty Acids. 2005 Jul;73(1):31-4. Review.PMID: 15936931 [PubMed - indexed for MEDLINE]Related articles

Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities.

Lay AJ, Liang Z, Rosen ED, Castellino FJ.

J Clin Invest. 2005 Jun;115(6):1552-61. Epub 2005 May 5.PMID: 15902301 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutational analysis of PPARG as a candidate tumour suppressor gene in enteropancreatic endocrine tumours.

Costa-Guda J, Rosen ED, Jensen RT, Chung DC, Arnold A.

Clin Endocrinol (Oxf). 2005 May;62(5):603-6.PMID: 15853832 [PubMed - indexed for MEDLINE]Related articles

Absence of a reductase, NCB5OR, causes insulin-deficient diabetes.

Xie J, Zhu H, Larade K, Ladoux A, Seguritan A, Chu M, Ito S, Bronson RT, Leiter EH, Zhang CY, Rosen ED, Bunn HF.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10750-5. Epub 2004 Jul 9.PMID: 15247412 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling.

Mix KS, Coon CI, Rosen ED, Suh N, Sporn MB, Brinckerhoff CE.

Mol Pharmacol. 2004 Feb;65(2):309-18.PMID: 14742672 [PubMed - indexed for MEDLINE]Related articlesFree article

Energy balance: a new role for PPARalpha.

Rosen ED.

Curr Biol. 2003 Dec 16;13(24):R961-3. Review. No abstract available. PMID: 14680654 [PubMed - indexed for MEDLINE]Related articles

Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis.

Rosen ED, Kulkarni RN, Sarraf P, Ozcan U, Okada T, Hsu CH, Eisenman D, Magnuson MA, Gonzalez FJ, Kahn CR, Spiegelman BM.

Mol Cell Biol. 2003 Oct;23(20):7222-9.PMID: 14517292 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones.

Norris AW, Chen L, Fisher SJ, Szanto I, Ristow M, Jozsi AC, Hirshman MF, Rosen ED, Goodyear LJ, Gonzalez FJ, Spiegelman BM, Kahn CR.

J Clin Invest. 2003 Aug;112(4):608-18.PMID: 12925701 [PubMed - indexed for MEDLINE]Related articlesFree article

In utero transplantation of wild-type fetal liver cells rescues factor X-deficient mice from fatal neonatal bleeding diatheses.

Rosen ED, Cornelissen I, Liang Z, Zollman A, Casad M, Roahrig J, Suckow M, Castellino FJ.

J Thromb Haemost. 2003 Jan;1(1):19-27.PMID: 12871535 [PubMed - indexed for MEDLINE]Related articles

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective.

Cheng T, Liu D, Griffin JH, Fernández JA, Castellino F, Rosen ED, Fukudome K, Zlokovic BV.

Nat Med. 2003 Mar;9(3):338-42. Epub 2003 Feb 3.PMID: 12563316 [PubMed - indexed for MEDLINE]Related articles

The molecular control of adipogenesis, with special reference to lymphatic pathology.

Rosen ED.

Ann N Y Acad Sci. 2002 Dec;979:143-58; discussion 188-96. Review.PMID: 12543724 [PubMed - indexed for MEDLINE]Related articles

Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge.

Castellino FJ, Liang Z, Volkir SP, Haalboom E, Martin JA, Sandoval-Cooper MJ, Rosen ED.

Thromb Haemost. 2002 Sep;88(3):462-72.PMID: 12353077 [PubMed - indexed for MEDLINE]Related articles

Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms.

Mueller E, Drori S, Aiyer A, Yie J, Sarraf P, Chen H, Hauser S, Rosen ED, Ge K, Roeder RG, Spiegelman BM.

J Biol Chem. 2002 Nov 1;277(44):41925-30. Epub 2002 Aug 27.PMID: 12200443 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene targeting in hemostasis. Factor X.

Rosen ED.

Front Biosci. 2002 Sep 1;7:d1915-25. Review.PMID: 12161341 [PubMed - indexed for MEDLINE]Related articles

FXI is essential for thrombus formation following FeCl3-induced injury of the carotid artery in the mouse.

Rosen ED, Gailani D, Castellino FJ.

Thromb Haemost. 2002 Apr;87(4):774-6. No abstract available. PMID: 12008966 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanisms of adipocyte differentiation.

Rosen ED.

Ann Endocrinol (Paris). 2002 Apr;63(2 Pt 1):79-82. Review. No abstract available. PMID: 11994665 [PubMed - indexed for MEDLINE]Related articles

C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway.

Rosen ED, Hsu CH, Wang X, Sakai S, Freeman MW, Gonzalez FJ, Spiegelman BM.

Genes Dev. 2002 Jan 1;16(1):22-6.PMID: 11782441 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of pulmonary fibrosis in fibrinogen-deficient mice.

Wilberding JA, Ploplis VA, McLennan L, Liang Z, Cornelissen I, Feldman M, Deford ME, Rosen ED, Castellino FJ.

Ann N Y Acad Sci. 2001;936:542-8. Review.PMID: 11460513 [PubMed - indexed for MEDLINE]Related articles

PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth.

Rosen ED, Spiegelman BM.

J Biol Chem. 2001 Oct 12;276(41):37731-4. Epub 2001 Jul 17. Review. No abstract available. PMID: 11459852 [PubMed - indexed for MEDLINE]Related articlesFree article

Laser-induced noninvasive vascular injury models in mice generate platelet- and coagulation-dependent thrombi.

Rosen ED, Raymond S, Zollman A, Noria F, Sandoval-Cooper M, Shulman A, Merz JL, Castellino FJ.

Am J Pathol. 2001 May;158(5):1613-22.PMID: 11337359 [PubMed - indexed for MEDLINE]Related articlesFree article

The characterization of mice with a targeted combined deficiency of protein c and factor XI.

Chan JC, Ganopolsky JG, Cornelissen I, Suckow MA, Sandoval-Cooper MJ, Brown EC, Noria F, Gailani D, Rosen ED, Ploplis VA, Castellino FJ.

Am J Pathol. 2001 Feb;158(2):469-79.PMID: 11159184 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.

Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW.

Nat Med. 2001 Jan;7(1):41-7.PMID: 11135614 [PubMed - indexed for MEDLINE]Related articles

Molecular regulation of adipogenesis.

Rosen ED, Spiegelman BM.

Annu Rev Cell Dev Biol. 2000;16:145-71. Review.PMID: 11031233 [PubMed - indexed for MEDLINE]Related articles

A total fibrinogen deficiency is compatible with the development of pulmonary fibrosis in mice.

Ploplis VA, Wilberding J, McLennan L, Liang Z, Cornelissen I, DeFord ME, Rosen ED, Castellino FJ.

Am J Pathol. 2000 Sep;157(3):703-8.PMID: 10980108 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor gamma ligands and atherosclerosis: ending the heartache.

Rosen ED, Spiegelman BM.

J Clin Invest. 2000 Sep;106(5):629-31. No abstract available. PMID: 10974014 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation.

Yoon JC, Chickering TW, Rosen ED, Dussault B, Qin Y, Soukas A, Friedman JM, Holmes WE, Spiegelman BM.

Mol Cell Biol. 2000 Jul;20(14):5343-9.PMID: 10866690 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional regulation of adipogenesis.

Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM.

Genes Dev. 2000 Jun 1;14(11):1293-307. Review. No abstract available. PMID: 10837022 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning and characterization of the murine coagulation factor X gene.

Cooper A, Liang Z, Castellino FJ, Rosen ED.

Thromb Haemost. 2000 May;83(5):732-5.PMID: 10823271 [PubMed - indexed for MEDLINE]Related articles

Blood coagulation factor X deficiency causes partial embryonic lethality and fatal neonatal bleeding in mice.

Dewerchin M, Liang Z, Moons L, Carmeliet P, Castellino FJ, Collen D, Rosen ED.

Thromb Haemost. 2000 Feb;83(2):185-90.PMID: 10739370 [PubMed - indexed for MEDLINE]Related articles

PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro.

Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, Milstone DS, Spiegelman BM, Mortensen RM.

Mol Cell. 1999 Oct;4(4):611-7.PMID: 10549292 [PubMed - indexed for MEDLINE]Related articles