PubMed

Endogenous BDNF in the dorsolateral striatum gates alcohol drinking.

Jeanblanc J, He DY, Carnicella S, Kharazia V, Janak PH, Ron D.

J Neurosci. 2009 Oct 28;29(43):13494-502.PMID: 19864562 [PubMed - in process]Related articles

Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling.

Woo CW, Cui D, Arellano J, Dorweiler B, Harding H, Fitzgerald KA, Ron D, Tabas I.

Nat Cell Biol. 2009 Oct 25. [Epub ahead of print]PMID: 19855386 [PubMed - as supplied by publisher]Related articles

Alteration of the Unfolded Protein Response Modifies Neurodegeneration in a Mouse Model of Marinesco-Sjogren Syndrome.

Zhao L, Rosales C, Seburn K, Ron D, Ackerman SL.

Hum Mol Genet. 2009 Oct 3. [Epub ahead of print]PMID: 19801575 [PubMed - as supplied by publisher]Related articlesFree article

Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis.

Li G, Mongillo M, Chin KT, Harding H, Ron D, Marks AR, Tabas I.

J Cell Biol. 2009 Sep 21;186(6):783-92. Epub 2009 Sep 14.PMID: 19752026 [PubMed - indexed for MEDLINE]Related articles

Blockade of ethanol reward by the kappa opioid receptor agonist U50,488H.

Logrip ML, Janak PH, Ron D.

Alcohol. 2009 Aug;43(5):359-65.PMID: 19671462 [PubMed - indexed for MEDLINE]Related articles

Infectious tolerance via the consumption of essential amino acids and mTOR signaling.

Cobbold SP, Adams E, Farquhar CA, Nolan KF, Howie D, Lui KO, Fairchild PJ, Mellor AL, Ron D, Waldmann H.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12055-60. Epub 2009 Jun 30.PMID: 19567830 [PubMed - indexed for MEDLINE]Related articlesFree article

Escalating ethanol intake is associated with altered corticostriatal BDNF expression.

Logrip ML, Janak PH, Ron D.

J Neurochem. 2009 Jun;109(5):1459-68. Epub 2009 Mar 28.PMID: 19453942 [PubMed - indexed for MEDLINE]Related articles

Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.

Thorp E, Li G, Seimon TA, Kuriakose G, Ron D, Tabas I.

Cell Metab. 2009 May;9(5):474-81.PMID: 19416717 [PubMed - indexed for MEDLINE]Related articles

Targeting of mRNAs to their sites of unconventional splicing in the unfolded protein response.

Ron D.

Mol Cell. 2009 Apr 24;34(2):133-4.PMID: 19394288 [PubMed - indexed for MEDLINE]Related articles

Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle.

Wiseman RL, Chin KT, Haynes CM, Stanhill A, Xu CF, Roguev A, Krogan NJ, Neubert TA, Ron D.

J Biol Chem. 2009 May 29;284(22):15233-45. Epub 2009 Apr 6.PMID: 19349280 [PubMed - indexed for MEDLINE]Related articles

GDNF is an endogenous negative regulator of ethanol-mediated reward and of ethanol consumption after a period of abstinence.

Carnicella S, Ahmadiantehrani S, Janak PH, Ron D.

Alcohol Clin Exp Res. 2009 Jun;33(6):1012-24. Epub 2009 Mar 19.PMID: 19302086 [PubMed - indexed for MEDLINE]Related articles

Cabergoline decreases alcohol drinking and seeking behaviors via glial cell line-derived neurotrophic factor.

Carnicella S, Ahmadiantehrani S, He DY, Nielsen CK, Bartlett SE, Janak PH, Ron D.

Biol Psychiatry. 2009 Jul 15;66(2):146-53. Epub 2009 Feb 20.PMID: 19232578 [PubMed - indexed for MEDLINE]Related articles

Excessive alcohol consumption is blocked by glial cell line-derived neurotrophic factor.

Carnicella S, Amamoto R, Ron D.

Alcohol. 2009 Feb;43(1):35-43.PMID: 19185208 [PubMed - indexed for MEDLINE]Related articles

Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development.

Harding HP, Zhang Y, Scheuner D, Chen JJ, Kaufman RJ, Ron D.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1832-7. Epub 2009 Jan 30.PMID: 19181853 [PubMed - indexed for MEDLINE]Related articlesFree article

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells.

Wang Q, Mora-Jensen H, Weniger MA, Perez-Galan P, Wolford C, Hai T, Ron D, Chen W, Trenkle W, Wiestner A, Ye Y.

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2200-5. Epub 2009 Jan 22.PMID: 19164757 [PubMed - indexed for MEDLINE]Related articlesFree article

Alpha4-containing GABAA receptors in the nucleus accumbens mediate moderate intake of alcohol.

Rewal M, Jurd R, Gill TM, He DY, Ron D, Janak PH.

J Neurosci. 2009 Jan 14;29(2):543-9.PMID: 19144854 [PubMed - indexed for MEDLINE]Related articlesFree article

Divergent effects of PERK and IRE1 signaling on cell viability.

Lin JH, Li H, Zhang Y, Ron D, Walter P.

PLoS One. 2009;4(1):e4170. Epub 2009 Jan 12.PMID: 19137072 [PubMed - indexed for MEDLINE]Related articlesFree article

GDNF--a potential target to treat addiction.

Carnicella S, Ron D.

Pharmacol Ther. 2009 Apr;122(1):9-18. Epub 2008 Dec 24. Review.PMID: 19136027 [PubMed - indexed for MEDLINE]Related articles

Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3.

Petrova K, Oyadomari S, Hendershot LM, Ron D.

EMBO J. 2008 Nov 5;27(21):2862-72. Epub 2008 Oct 16.PMID: 18923430 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma.

Lin W, Kunkler PE, Harding HP, Ron D, Kraig RP, Popko B.

Am J Pathol. 2008 Nov;173(5):1508-17. Epub 2008 Sep 25.PMID: 18818381 [PubMed - indexed for MEDLINE]Related articlesFree article

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.

Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ.

J Clin Invest. 2008 Oct;118(10):3378-89.PMID: 18776938 [PubMed - indexed for MEDLINE]Related articlesFree article

Toward the discovery of new antifungal agents: the design and validation of a novel 2'P-RNA probe and high throughput screening assay against 2'-phosphotransferase Tpt1p.

Lackey JG, Ron D, Damha MJ, Harding HP.

Nucleic Acids Symp Ser (Oxf). 2008;(52):475-6.PMID: 18776460 [PubMed - in process]Related articlesFree article

PKCbetaII modulates translation independently from mTOR and through RACK1.

Grosso S, Volta V, Sala LA, Vietri M, Marchisio PC, Ron D, Biffo S.

Biochem J. 2008 Oct 1;415(1):77-85.PMID: 18557705 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel function of PERK as a mediator of force-induced apoptosis.

Mak BC, Wang Q, Laschinger C, Lee W, Ron D, Harding HP, Kaufman RJ, Scheuner D, Austin RC, McCulloch CA.

J Biol Chem. 2008 Aug 22;283(34):23462-72. Epub 2008 Jun 11.PMID: 18550523 [PubMed - indexed for MEDLINE]Related articlesFree article

GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse.

Carnicella S, Kharazia V, Jeanblanc J, Janak PH, Ron D.

Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):8114-9. Epub 2008 Jun 9.PMID: 18541917 [PubMed - indexed for MEDLINE]Related articlesFree article

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice.

Oyadomari S, Harding HP, Zhang Y, Oyadomari M, Ron D.

Cell Metab. 2008 Jun;7(6):520-32.PMID: 18522833 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans.

Yun C, Stanhill A, Yang Y, Zhang Y, Haynes CM, Xu CF, Neubert TA, Mor A, Philips MR, Ron D.

Proc Natl Acad Sci U S A. 2008 May 13;105(19):7094-9. Epub 2008 May 8.PMID: 18467495 [PubMed - indexed for MEDLINE]Related articlesFree article

IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA.

Iqbal J, Dai K, Seimon T, Jungreis R, Oyadomari M, Kuriakose G, Ron D, Tabas I, Hussain MM.

Cell Metab. 2008 May;7(5):445-55.PMID: 18460335 [PubMed - indexed for MEDLINE]Related articlesFree article

Know thy Sef: a novel class of feedback antagonists of receptor tyrosine kinase signaling.

Ron D, Fuchs Y, Chorev DS.

Int J Biochem Cell Biol. 2008;40(10):2040-52. Epub 2008 Mar 25. Review.PMID: 18450498 [PubMed - indexed for MEDLINE]Related articles

Glial cell line-derived neurotrophic factor reverses ethanol-mediated increases in tyrosine hydroxylase immunoreactivity via altering the activity of heat shock protein 90.

He DY, Ron D.

J Biol Chem. 2008 May 9;283(19):12811-8. Epub 2008 Mar 14.PMID: 18343820 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynorphin is a downstream effector of striatal BDNF regulation of ethanol intake.

Logrip ML, Janak PH, Ron D.

FASEB J. 2008 Jul;22(7):2393-404. Epub 2008 Feb 29.PMID: 18310464 [PubMed - indexed for MEDLINE]Related articlesFree article

Preliminary X-ray crystallographic studies of mouse UPR responsive protein P58(IPK) TPR fragment.

Tao J, Wu Y, Ron D, Sha B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Feb 1;64(Pt 2):108-10. Epub 2008 Jan 31.PMID: 18259061 [PubMed - indexed for MEDLINE]Related articles

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice.

Pennuto M, Tinelli E, Malaguti M, Del Carro U, D'Antonio M, Ron D, Quattrini A, Feltri ML, Wrabetz L.

Neuron. 2008 Feb 7;57(3):393-405.PMID: 18255032 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation.

Patel VN, Likar KM, Zisman-Rozen S, Cowherd SN, Lassiter KS, Sher I, Yates EA, Turnbull JE, Ron D, Hoffman MP.

J Biol Chem. 2008 Apr 4;283(14):9308-17. Epub 2008 Jan 28.PMID: 18230614 [PubMed - indexed for MEDLINE]Related articlesFree article

How IRE1 reacts to ER stress.

Ron D, Hubbard SR.

Cell. 2008 Jan 11;132(1):24-6. Review.PMID: 18191217 [PubMed - indexed for MEDLINE]Related articles

An intact unfolded protein response in Trpt1 knockout mice reveals phylogenic divergence in pathways for RNA ligation.

Harding HP, Lackey JG, Hsu HC, Zhang Y, Deng J, Xu RM, Damha MJ, Ron D.

RNA. 2008 Feb;14(2):225-32. Epub 2007 Dec 19.PMID: 18094117 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of the eukaryotic initiation factor 2 alpha-subunit kinase PERK by tyrosine phosphorylation.

Su Q, Wang S, Gao HQ, Kazemi S, Harding HP, Ron D, Koromilas AE.

J Biol Chem. 2008 Jan 4;283(1):469-75. Epub 2007 Nov 12.PMID: 17998206 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and regulation of Sef, a novel signaling inhibitor of receptor tyrosine kinases-mediated signaling in the nervous system.

Grothe C, Claus P, Haastert K, Lutwak E, Ron D.

Acta Histochem. 2008;110(2):155-62. Epub 2007 Nov 5.PMID: 17980404 [PubMed - indexed for MEDLINE]Related articles

Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner.

Jurd R, Thornton C, Wang J, Luong K, Phamluong K, Kharazia V, Gibb SL, Ron D.

J Biol Chem. 2008 Jan 4;283(1):301-10. Epub 2007 Oct 25.PMID: 17962190 [PubMed - indexed for MEDLINE]Related articlesFree article

ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans.

Haynes CM, Petrova K, Benedetti C, Yang Y, Ron D.

Dev Cell. 2007 Oct;13(4):467-80.PMID: 17925224 [PubMed - indexed for MEDLINE]Related articles

Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability.

Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, Yin XM.

Am J Pathol. 2007 Aug;171(2):513-24. Epub 2007 Jul 9.PMID: 17620365 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase C and alcohol addiction.

Newton PM, Ron D.

Pharmacol Res. 2007 Jun;55(6):570-7. Epub 2007 Apr 29. Review.PMID: 17566760 [PubMed - indexed for MEDLINE]Related articles

Signal integration in the endoplasmic reticulum unfolded protein response.

Ron D, Walter P.

Nat Rev Mol Cell Biol. 2007 Jul;8(7):519-29. Review.PMID: 17565364 [PubMed - indexed for MEDLINE]Related articles

Downregulation of Sef, an inhibitor of receptor tyrosine kinase signaling, is common to a variety of human carcinomas.

Zisman-Rozen S, Fink D, Ben-Izhak O, Fuchs Y, Brodski A, Kraus MH, Bejar J, Ron D.

Oncogene. 2007 Sep 6;26(41):6093-8. Epub 2007 Apr 9.PMID: 17420726 [PubMed - indexed for MEDLINE]Related articles

Ethanol induces long-term facilitation of NR2B-NMDA receptor activity in the dorsal striatum: implications for alcohol drinking behavior.

Wang J, Carnicella S, Phamluong K, Jeanblanc J, Ronesi JA, Chaudhri N, Janak PH, Lovinger DM, Ron D.

J Neurosci. 2007 Mar 28;27(13):3593-602.PMID: 17392475 [PubMed - indexed for MEDLINE]Related articlesFree article

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux.

Shang J, Gao N, Kaufman RJ, Ron D, Harding HP, Lehrman MA.

J Cell Biol. 2007 Feb 26;176(5):605-16.PMID: 17325203 [PubMed - indexed for MEDLINE]Related articlesFree article

The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage.

Lin W, Bailey SL, Ho H, Harding HP, Ron D, Miller SD, Popko B.

J Clin Invest. 2007 Feb;117(2):448-56.PMID: 17273557 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting translation in hypoxic tumors.

Ron D, Hinnebusch AG.

ACS Chem Biol. 2006 Apr 25;1(3):145-8.PMID: 17163661 [PubMed - indexed for MEDLINE]Related articles

ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae.

Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G.

Cell Metab. 2006 Dec;4(6):441-51.PMID: 17141628 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated expression of FGF7 protein is common in human gastric diseases.

Shaoul R, Eliahu L, Sher I, Hamlet Y, Miselevich I, Goldshmidt O, Ron D.

Biochem Biophys Res Commun. 2006 Dec 1;350(4):825-33. Epub 2006 Oct 2.PMID: 17049492 [PubMed - indexed for MEDLINE]Related articles