PubMed

Effect of the alpha(4)beta(2)( *) nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in beta2 knock-out mice with selective re-expression of the beta2 subunit in the ventral tegmental area.

Reperant C, Pons S, Dufour E, Rollema H, Gardier AM, Maskos U.

Neuropharmacology. 2009 Nov 1. [Epub ahead of print]PMID: 19887076 [PubMed - as supplied by publisher]Related articles

Varenicline overdose in a teenager--a clinical pharmacology perspective.

Rollema H, Faessel HM, Williams KE.

Clin Toxicol (Phila). 2009 Jul;47(6):605. No abstract available. PMID: 19586362 [PubMed - indexed for MEDLINE]Related articles

Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition.

Rollema H, Hajós M, Seymour PA, Kozak R, Majchrzak MJ, Guanowsky V, Horner WE, Chapin DS, Hoffmann WE, Johnson DE, McLean S, Freeman J, Williams KE.

Biochem Pharmacol. 2009 Oct 1;78(7):813-24. Epub 2009 Jun 6.PMID: 19501054 [PubMed - indexed for MEDLINE]Related articles

Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect.

Rollema H, Guanowsky V, Mineur YS, Shrikhande A, Coe JW, Seymour PA, Picciotto MR.

Eur J Pharmacol. 2009 Mar 1;605(1-3):114-6. Epub 2009 Jan 10.PMID: 19168054 [PubMed - indexed for MEDLINE]Related articles

Differential Effects of Various Typical and Atypical Antipsychotics on Plasma Glucose and Insulin Levels in the Mouse: Evidence for the Involvement of Sympathetic Regulation.

Savoy YE, Ashton MA, Miller MW, Nedza FM, Spracklin DK, Hawthorn MH, Rollema H, Matos FF, Hajos-Korcsok E.

Schizophr Bull. 2008 Aug 14. [Epub ahead of print]PMID: 18703666 [PubMed - as supplied by publisher]Related articles

Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation.

Rollema H, Coe JW, Chambers LK, Hurst RS, Stahl SM, Williams KE.

Trends Pharmacol Sci. 2007 Jul;28(7):316-25. Epub 2007 Jun 18. Review.PMID: 17573127 [PubMed - indexed for MEDLINE]Related articles

Central nervous system pharmacokinetics of the Mdr1 P-glycoprotein substrate CP-615,003: intersite differences and implications for human receptor occupancy projections from cerebrospinal fluid exposures.

Venkatakrishnan K, Tseng E, Nelson FR, Rollema H, French JL, Kaplan IV, Horner WE, Gibbs MA.

Drug Metab Dispos. 2007 Aug;35(8):1341-9. Epub 2007 Apr 30.PMID: 17470526 [PubMed - indexed for MEDLINE]Related articlesFree article

AAPS-FDA workshop white paper: microdialysis principles, application and regulatory perspectives.

Chaurasia CS, Müller M, Bashaw ED, Benfeldt E, Bolinder J, Bullock R, Bungay PM, DeLange EC, Derendorf H, Elmquist WF, Hammarlund-Udenaes M, Joukhadar C, Kellogg DL Jr, Lunte CE, Nordstrom CH, Rollema H, Sawchuk RJ, Cheung BW, Shah VP, Stahle L, Ungerstedt U, Welty DF, Yeo H.

Pharm Res. 2007 May;24(5):1014-25. Epub 2007 Mar 27.PMID: 17458685 [PubMed - indexed for MEDLINE]Related articles

AAPS-FDA Workshop White Paper: microdialysis principles, application, and regulatory perspectives.

Chaurasia CS, Müller M, Bashaw ED, Benfeldt E, Bolinder J, Bullock R, Bungay PM, DeLange EC, Derendorf H, Elmquist WF, Hammarlund-Udenaes M, Joukhadar C, Kellogg DL Jr, Lunte CE, Nordstrom CH, Rollema H, Sawchuk RJ, Cheung BW, Shah VP, Stahle L, Ungerstedt U, Welty DF, Yeo H.

J Clin Pharmacol. 2007 May;47(5):589-603. No abstract available. PMID: 17442685 [PubMed - indexed for MEDLINE]Related articles

Varenicline: new treatment with efficacy in smoking cessation.

Reus VI, Obach RS, Coe JW, Faessel H, Rollema H, Watsky E, Reeves K.

Drugs Today (Barc). 2007 Feb;43(2):65-75. Review.PMID: 17353944 [PubMed - indexed for MEDLINE]Related articles

Methylphenidate and atomoxetine increase histamine release in rat prefrontal cortex.

Horner WE, Johnson DE, Schmidt AW, Rollema H.

Eur J Pharmacol. 2007 Mar 8;558(1-3):96-7. Epub 2006 Dec 1.PMID: 17198700 [PubMed - indexed for MEDLINE]Related articles

Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid.

Rollema H, Chambers LK, Coe JW, Glowa J, Hurst RS, Lebel LA, Lu Y, Mansbach RS, Mather RJ, Rovetti CC, Sands SB, Schaeffer E, Schulz DW, Tingley FD 3rd, Williams KE.

Neuropharmacology. 2007 Mar;52(3):985-94. Epub 2006 Dec 8.PMID: 17157884 [PubMed - indexed for MEDLINE]Related articles

Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: implications for adverse metabolic effects.

Houseknecht KL, Robertson AS, Zavadoski W, Gibbs EM, Johnson DE, Rollema H.

Neuropsychopharmacology. 2007 Feb;32(2):289-97. Epub 2006 Oct 11.PMID: 17035934 [PubMed - indexed for MEDLINE]Related articlesFree article

3,5-Bicyclic aryl piperidines: a novel class of alpha4beta2 neuronal nicotinic receptor partial agonists for smoking cessation.

Coe JW, Brooks PR, Wirtz MC, Bashore CG, Bianco KE, Vetelino MG, Arnold EP, Lebel LA, Fox CB, Tingley FD 3rd, Schulz DW, Davis TI, Sands SB, Mansbach RS, Rollema H, O'Neill BT.

Bioorg Med Chem Lett. 2005 Nov 15;15(22):4889-97.PMID: 16171993 [PubMed - indexed for MEDLINE]Related articles

In pursuit of alpha4beta2 nicotinic receptor partial agonists for smoking cessation: carbon analogs of (-)-cytisine.

Coe JW, Vetelino MG, Bashore CG, Wirtz MC, Brooks PR, Arnold EP, Lebel LA, Fox CB, Sands SB, Davis TI, Schulz DW, Rollema H, Tingley FD 3rd, O'Neill BT.

Bioorg Med Chem Lett. 2005 Jun 15;15(12):2974-9.PMID: 15908213 [PubMed - indexed for MEDLINE]Related articles

Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation.

Coe JW, Brooks PR, Vetelino MG, Wirtz MC, Arnold EP, Huang J, Sands SB, Davis TI, Lebel LA, Fox CB, Shrikhande A, Heym JH, Schaeffer E, Rollema H, Lu Y, Mansbach RS, Chambers LK, Rovetti CC, Schulz DW, Tingley FD 3rd, O'Neill BT.

J Med Chem. 2005 May 19;48(10):3474-7.PMID: 15887955 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from perifused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia.

Johnson DE, Yamazaki H, Ward KM, Schmidt AW, Lebel WS, Treadway JL, Gibbs EM, Zawalich WS, Rollema H.

Diabetes. 2005 May;54(5):1552-8.PMID: 15855345 [PubMed - indexed for MEDLINE]Related articlesFree article

The structure of kappa/iota-hybrid carrageenans II. Coil-helix transition as a function of chain composition.

van de Velde F, Antipova AS, Rollema HS, Burova TV, Grinberg NV, Pereira L, Gilsenan PM, Tromp RH, Rudolph B, Grinberg VY.

Carbohydr Res. 2005 May 2;340(6):1113-29.PMID: 15797127 [PubMed - indexed for MEDLINE]Related articles

The role of muscarinic receptor antagonism in antipsychotic-induced hippocampal acetylcholine release.

Johnson DE, Nedza FM, Spracklin DK, Ward KM, Schmidt AW, Iredale PA, Godek DM, Rollema H.

Eur J Pharmacol. 2005 Jan 4;506(3):209-19. Epub 2004 Dec 15.PMID: 15627430 [PubMed - indexed for MEDLINE]Related articles

The revised NMR chemical shift data of carrageenans.

van de Velde F, Pereira L, Rollema HS.

Carbohydr Res. 2004 Sep 13;339(13):2309-13.PMID: 15337460 [PubMed - indexed for MEDLINE]Related articles

Diffusivity of whey protein and gum arabic in their coacervates.

Weinbreck F, Rollema HS, Tromp RH, de Kruif CG.

Langmuir. 2004 Jul 20;20(15):6389-95.PMID: 15248727 [PubMed - indexed for MEDLINE]Related articles

Gelation mechanism of milk as influenced by temperature and pH; studied by the use of transglutaminase cross-linked casein micelles.

Vasbinder AJ, Rollema HS, Bot A, de Kruif CG.

J Dairy Sci. 2003 May;86(5):1556-63.PMID: 12778566 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired rennetability of heated milk; study of enzymatic hydrolysis and gelation kinetics.

Vasbinder AJ, Rollema HS, de Kruif CG.

J Dairy Sci. 2003 May;86(5):1548-55.PMID: 12778565 [PubMed - indexed for MEDLINE]Related articlesFree article

Coil-helix transition of iota-carrageenan as a function of chain regularity.

van de Velde F, Rollema HS, Grinberg NV, Burova TV, Grinberg VY, Tromp RH.

Biopolymers. 2002 Nov 15;65(4):299-312.PMID: 12382290 [PubMed - indexed for MEDLINE]Related articles

Serotonergic effects and extracellular brain levels of eletriptan, zolmitriptan and sumatriptan in rat brain.

Johnson DE, Rollema H, Schmidt AW, McHarg AD.

Eur J Pharmacol. 2001 Aug 17;425(3):203-10.PMID: 11513839 [PubMed - indexed for MEDLINE]Related articles

On the structure of kappa/iota-hybrid carrageenans.

van de Velde F, Peppelman HA, Rollema HS, Tromp RH.

Carbohydr Res. 2001 Apr 12;331(3):271-83.PMID: 11383897 [PubMed - indexed for MEDLINE]Related articles

Activation of postsynaptic 5-HT(1A) receptors by fluoxetine despite the loss of firing-dependent serotonergic input: electrophysiological and neurochemical studies.

Sprouse J, Braselton J, Reynolds L, Clarke T, Rollema H.

Synapse. 2001 Jul;41(1):49-57.PMID: 11354013 [PubMed - indexed for MEDLINE]Related articles

5-HT(1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex.

Rollema H, Lu Y, Schmidt AW, Sprouse JS, Zorn SH.

Biol Psychiatry. 2000 Aug 1;48(3):229-37.PMID: 10924666 [PubMed - indexed for MEDLINE]Related articles

Engineering a disulfide bond and free thiols in the lantibiotic nisin Z.

van Kraaij C, Breukink E, Rollema HS, Bongers RS, Kosters HA, de Kruijff B, Kuipers OP.

Eur J Biochem. 2000 Feb;267(3):901-9.PMID: 10651829 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of the novel antipsychotic ziprasidone with clozapine and olanzapine: inhibition of dorsal raphe cell firing and the role of 5-HT1A receptor activation.

Sprouse JS, Reynolds LS, Braselton JP, Rollema H, Zorn SH.

Neuropsychopharmacology. 1999 Nov;21(5):622-31.PMID: 10516958 [PubMed - indexed for MEDLINE]Related articlesFree article

Continued improvement in pressure-flow parameters in men receiving finasteride for 2 years. Finasteride Urodynamics Study Group.

Schäfer W, Tammela TL, Barrett DM, Abrams P, Hedlund H, Rollema HJ, Nordling J, Andersen JT, Hald T, Matos-Ferriera A, Bruskewitz R, Miller P, Mustonen S, Cannon A, Malice MP, Jacobsen CA, Bach MA.

Urology. 1999 Aug;54(2):278-83.PMID: 10443725 [PubMed - indexed for MEDLINE]Related articles

Improvement of pressure flow parameters with finasteride is greater in men with large prostates. Finasteride Urodynamics Study Group.

Abrams P, Schäfer W, Tammela TL, Barrett DM, Hedlund H, Rollema HJ, Matos-Ferreira A, Nordling J, Bruskewitz R, Andersen JT, Hald T, Miller P, Kirby R, Mustonen S, Cannon A, Jacobsen CA, Gormley GJ, Malice MP, Bach MA.

J Urol. 1999 May;161(5):1513-7.PMID: 10210385 [PubMed - indexed for MEDLINE]Related articles

Repeated pressure-flow studies in the evaluation of bladder outlet obstruction due to benign prostatic enlargement. Finasteride Urodynamics Study Group.

Tammela TL, Schäfer W, Barrett DM, Abrams P, Hedlund H, Rollema HJ, Matos-Ferreira A, Nordling J, Bruskewitz R, Miller P, Kirby R, Andersen JT, Jacobsen C, Gormley GJ, Malice MP, Bach MA.

Neurourol Urodyn. 1999;18(1):17-24.PMID: 10090123 [PubMed - indexed for MEDLINE]Related articles

Consequences of 5-HT re-uptake blockade on postsynaptic 5-HT1A receptor activation: an electrophysiological and neurochemical study in guinea pig dorsal raphe and hippocampus.

Sprouse J, Braselton J, Reynolds L, Clarke T, Rollema H.

Ann N Y Acad Sci. 1998 Dec 15;861:272-3. No abstract available. PMID: 9928286 [PubMed - indexed for MEDLINE]Related articles

Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation.

Rollema H, Lu Y, Schmidt AW, Zorn SH.

Eur J Pharmacol. 1997 Nov 5;338(2):R3-5.PMID: 9456005 [PubMed - indexed for MEDLINE]Related articles

Structural features of the final intermediate in the biosynthesis of the lantibiotic nisin. Influence of the leader peptide.

van den Hooven HW, Rollema HS, Siezen RJ, Hilbers CW, Kuipers OP.

Biochemistry. 1997 Nov 18;36(46):14137-45.PMID: 9369486 [PubMed - indexed for MEDLINE]Related articles

Influence of charge differences in the C-terminal part of nisin on antimicrobial activity and signaling capacity.

Van Kraaij C, Breukink E, Rollema HS, Siezen RJ, Demel RA, De Kruijff B, Kuipers OP.

Eur J Biochem. 1997 Jul 1;247(1):114-20.PMID: 9249016 [PubMed - indexed for MEDLINE]Related articlesFree article

Do 5-HT1B/1D autoreceptors modulate dorsal raphe cell firing? In vivo electrophysiological studies in guinea pigs with GR127935.

Sprouse J, Reynolds L, Rollema H.

Neuropharmacology. 1997 Apr-May;36(4-5):559-67.PMID: 9225281 [PubMed - indexed for MEDLINE]Related articles

[Determination of infravesical obstruction in men with benign prostatic hyperplasia using pressure-flow measurement and analysis with the Dx/CLIM software program]

Svihra J, Bos R, Rollema HJ, Janknegt RA.

Bratisl Lek Listy. 1997 Jan;98(1):28-31. Slovak. PMID: 9264802 [PubMed - indexed for MEDLINE]Related articles

Standardization of terminology of lower urinary tract function: pressure-flow studies of voiding, urethral resistance, and urethral obstruction. International Continence Society Subcommittee on Standardization of Terminology of Pressure-Flow Studies.

Griffiths D, Höfner K, van Mastrigt R, Rollema HJ, Spångberg A, Gleason D.

Neurourol Urodyn. 1997;16(1):1-18. No abstract available. PMID: 9021786 [PubMed - indexed for MEDLINE]Related articles

Structure and biological activity of chemically modified nisin A species.

Rollema HS, Metzger JW, Both P, Kuipers OP, Siezen RJ.

Eur J Biochem. 1996 Nov 1;241(3):716-22.PMID: 8944757 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo.

Rollema H, Clarke T, Sprouse JS, Schulz DW.

J Neurochem. 1996 Nov;67(5):2204-7.PMID: 8863532 [PubMed - indexed for MEDLINE]Related articles

Reversed-phase high-performance liquid chromatographic separation of bovine kappa-casein macropeptide and characterization of isolated fractions.

Minikiewicz P, Slangen CJ, Lagerwerf FM, Haverkamp J, Rollema HS, Visser S.

J Chromatogr A. 1996 Aug 30;743(1):123-35.PMID: 8817876 [PubMed - indexed for MEDLINE]Related articles

The structure of the lantibiotic lacticin 481 produced by Lactococcus lactis: location of the thioether bridges.

van den Hooven HW, Lagerwerf FM, Heerma W, Haverkamp J, Piard JC, Hilbers CW, Siezen RJ, Kuipers OP, Rollema HS.

FEBS Lett. 1996 Aug 12;391(3):317-22.PMID: 8764998 [PubMed - indexed for MEDLINE]Related articles

Comparison of the effects of sertraline and its metabolite desmethylsertraline on blockade of central 5-HT reuptake in vivo.

Sprouse J, Clarke T, Reynolds L, Heym J, Rollema H.

Neuropsychopharmacology. 1996 Apr;14(4):225-31.PMID: 8924190 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein engineering of lantibiotics.

Kuipers OP, Bierbaum G, Ottenwälder B, Dodd HM, Horn N, Metzger J, Kupke T, Gnau V, Bongers R, van den Bogaard P, Kosters H, Rollema HS, de Vos WM, Siezen RJ, Jung G, Götz F, Sahl HG, Gasson MJ.

Antonie Van Leeuwenhoek. 1996 Feb;69(2):161-69. Review.PMID: 8775976 [PubMed - indexed for MEDLINE]Related articles

Relationship between analgesia and extracellular morphine in brain and spinal cord in awake rats.

Matos FF, Rollema H, Taiwo YO, Levine JD, Basbaum AI.

Brain Res. 1995 Sep 25;693(1-2):187-95.PMID: 8653407 [PubMed - indexed for MEDLINE]Related articles

Improvement of solubility and stability of the antimicrobial peptide nisin by protein engineering.

Rollema HS, Kuipers OP, Both P, de Vos WM, Siezen RJ.

Appl Environ Microbiol. 1995 Aug;61(8):2873-8.PMID: 7487019 [PubMed - indexed for MEDLINE]Related articlesFree article

Homology modelling of the Lactococcus lactis leader peptidase NisP and its interaction with the precursor of the lantibiotic nisin.

Siezen RJ, Rollema HS, Kuipers OP, de Vos WM.

Protein Eng. 1995 Feb;8(2):117-25.PMID: 7630881 [PubMed - indexed for MEDLINE]Related articles

Lactococcal expression systems for protein engineering of nisin.

Kuipers OP, Rollema HS, Siezen RJ, De Vos WM.

Dev Biol Stand. 1995;85:605-13. No abstract available. PMID: 8586239 [PubMed - indexed for MEDLINE]Related articles