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    Results: 28

    1.

    Mutations in the DNA-binding domain of NR2E3 affect in vivo dimerization and interaction with CRX.

    Roduit R, Escher P, Schorderet DF.

    PLoS One. 2009 Oct 12;4(10):e7379.PMID: 19823680 [PubMed - in process]Related articlesFree article

    2.

    Mutations in NR2E3 can cause dominant or recessive retinal degenerations in the same family.

    Escher P, Gouras P, Roduit R, Tiab L, Bolay S, Delarive T, Chen S, Tsai CC, Hayashi M, Zernant J, Merriam JE, Mermod N, Allikmets R, Munier FL, Schorderet DF.

    Hum Mutat. 2009 Mar;30(3):342-51.PMID: 19006237 [PubMed - indexed for MEDLINE]Related articles

    3.

    Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases.

    Maedler K, Schulthess FT, Bielman C, Berney T, Bonny C, Prentki M, Donath MY, Roduit R.

    FASEB J. 2008 Jun;22(6):1905-13. Epub 2008 Feb 8.PMID: 18263705 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells.

    Roduit R, Schorderet DF.

    Apoptosis. 2008 Mar;13(3):343-53.PMID: 18253836 [PubMed - indexed for MEDLINE]Related articles

    5.

    Homogeneous and nonradioactive high-throughput screening platform for the characterization of kinase inhibitors in cell lysates.

    Guenat S, Rouleau N, Bielmann C, Bedard J, Maurer F, Allaman-Pillet N, Nicod P, Bielefeld-Sévigny M, Beckmann JS, Bonny C, Bossé R, Roduit R.

    J Biomol Screen. 2006 Dec;11(8):1015-26. Epub 2006 Nov 7.PMID: 17092917 [PubMed - indexed for MEDLINE]Related articles

    6.

    A unique set of SH3-SH3 interactions controls IB1 homodimerization.

    Kristensen O, Guenat S, Dar I, Allaman-Pillet N, Abderrahmani A, Ferdaoussi M, Roduit R, Maurer F, Beckmann JS, Kastrup JS, Gajhede M, Bonny C.

    EMBO J. 2006 Feb 22;25(4):785-97. Epub 2006 Feb 2.PMID: 16456539 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Malonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytes.

    Joly E, Bendayan M, Roduit R, Saha AK, Ruderman NB, Prentki M.

    FEBS Lett. 2005 Dec 5;579(29):6581-6. Epub 2005 Nov 9.PMID: 16298369 [PubMed - indexed for MEDLINE]Related articles

    8.

    Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure.

    Abdelli S, Ansite J, Roduit R, Borsello T, Matsumoto I, Sawada T, Allaman-Pillet N, Henry H, Beckmann JS, Hering BJ, Bonny C.

    Diabetes. 2004 Nov;53(11):2815-23.PMID: 15504961 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Circadian regulation of islet genes involved in insulin production and secretion.

    Allaman-Pillet N, Roduit R, Oberson A, Abdelli S, Ruiz J, Beckmann JS, Schorderet DF, Bonny C.

    Mol Cell Endocrinol. 2004 Oct 29;226(1-2):59-66.PMID: 15489006 [PubMed - indexed for MEDLINE]Related articles

    10.

    Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation.

    Gremlich S, Nolan C, Roduit R, Burcelin R, Peyot ML, Delghingaro-Augusto V, Desvergne B, Michalik L, Prentki M, Wahli W.

    Endocrinology. 2005 Jan;146(1):375-82. Epub 2004 Sep 30.PMID: 15459119 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.

    Roduit R, Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Massé F, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M.

    Diabetes. 2004 Apr;53(4):1007-19.PMID: 15047616 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1.

    Allaman-Pillet N, Størling J, Oberson A, Roduit R, Negri S, Sauser C, Nicod P, Beckmann JS, Schorderet DF, Mandrup-Poulsen T, Bonny C.

    J Biol Chem. 2003 Dec 5;278(49):48720-6. Epub 2003 Sep 24.PMID: 14507925 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    DcR3/TR6 effectively prevents islet primary nonfunction after transplantation.

    Wu Y, Han B, Luo H, Roduit R, Salcedo TW, Moore PA, Zhang J, Wu J.

    Diabetes. 2003 Sep;52(9):2279-86.PMID: 12941767 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death.

    El-Assaad W, Buteau J, Peyot ML, Nolan C, Roduit R, Hardy S, Joly E, Dbaibo G, Rosenberg L, Prentki M.

    Endocrinology. 2003 Sep;144(9):4154-63.PMID: 12933690 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes.

    Prentki M, Joly E, El-Assaad W, Roduit R.

    Diabetes. 2002 Dec;51 Suppl 3:S405-13. Review.PMID: 12475783 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice.

    Roduit R, Masiello P, Wang SP, Li H, Mitchell GA, Prentki M.

    Diabetes. 2001 Sep;50(9):1970-5.PMID: 11522661 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Lipoprotein lipase and leptin are accumulated in different secretory compartments in rat adipocytes.

    Roh C, Roduit R, Thorens B, Fried S, Kandror KV.

    J Biol Chem. 2001 Sep 21;276(38):35990-4. Epub 2001 Jul 12.PMID: 11451949 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell.

    Roduit R, Morin J, Massé F, Segall L, Roche E, Newgard CB, Assimacopoulos-Jeannet F, Prentki M.

    J Biol Chem. 2000 Nov 17;275(46):35799-806.PMID: 10967113 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-beta -D-ribofuranoside.

    Saha AK, Schwarsin AJ, Roduit R, Masse F, Kaushik V, Tornheim K, Prentki M, Ruderman NB.

    J Biol Chem. 2000 Aug 11;275(32):24279-83.PMID: 10854420 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells.

    Buteau J, Roduit R, Susini S, Prentki M.

    Diabetologia. 1999 Jul;42(7):856-64.PMID: 10440129 [PubMed - indexed for MEDLINE]Related articles

    21.

    Cloning and expression of rat pancreatic beta-cell malonyl-CoA decarboxylase.

    Voilley N, Roduit R, Vicaretti R, Bonny C, Waeber G, Dyck JR, Lopaschuk GD, Prentki M.

    Biochem J. 1999 May 15;340 ( Pt 1):213-7.PMID: 10229677 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Leptin inhibits directly glucocorticoid secretion by normal human and rat adrenal gland.

    Pralong FP, Roduit R, Waeber G, Castillo E, Mosimann F, Thorens B, Gaillard RC.

    Endocrinology. 1998 Oct;139(10):4264-8.PMID: 9751508 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    The loss of GLUT2 expression in the pancreatic beta-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors.

    Bonny C, Roduit R, Gremlich S, Nicod P, Thorens B, Waeber G.

    Mol Cell Endocrinol. 1997 Nov 30;135(1):59-65.PMID: 9453241 [PubMed - indexed for MEDLINE]Related articles

    24.

    Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin.

    Roduit R, Thorens B.

    FEBS Lett. 1997 Sep 29;415(2):179-82.PMID: 9350991 [PubMed - indexed for MEDLINE]Related articles

    25.

    Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor.

    Waeber G, Calandra T, Roduit R, Haefliger JA, Bonny C, Thompson N, Thorens B, Temler E, Meinhardt A, Bacher M, Metz CN, Nicod P, Bucala R.

    Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4782-7.PMID: 9114069 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic beta cells. Comparison with the effects of fatty acids.

    Gremlich S, Roduit R, Thorens B.

    J Biol Chem. 1997 Feb 7;272(6):3216-22.PMID: 9013557 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    [1996 Apollinaire Bouchardat Prize. Molecular aspects of control of insulin secretion]

    Thorens B, Gremlich S, Roduit R, Widmann C.

    Journ Annu Diabetol Hotel Dieu. 1996:55-68. French. No abstract available. PMID: 8965432 [PubMed - indexed for MEDLINE]Related articles

    28.

    Regulated expression of GLUT2 in diabetes studied in transplanted pancreatic beta cells.

    Thorens B, Roduit R.

    Biochem Soc Trans. 1994 Aug;22(3):684-7. Review.PMID: 7821664 [PubMed - indexed for MEDLINE]Related articles

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