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mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition.

Bhaskar PT, Nogueira V, Patra KC, Jeon SM, Park Y, Robey RB, Hay N.

Mol Cell Biol. 2009 Sep;29(18):5136-47. Epub 2009 Jul 20.PMID: 19620286 [PubMed - indexed for MEDLINE]Related articles

Reduced susceptibility to azoxymethane-induced aberrant crypt foci formation and colon cancer in growth hormone deficient rats.

Carroll RE, Goodlad RA, Poole AJ, Tyner AL, Robey RB, Swanson SM, Unterman TG.

Growth Horm IGF Res. 2009 Oct;19(5):447-56. Epub 2009 Apr 29.PMID: 19406679 [PubMed - in process]Related articles

Does furosemide have a role in the management of hypercalcemia?

Robey RB, Lash JP, Arruda JA.

Ann Intern Med. 2009 Jan 20;150(2):146-7; author reply 147. No abstract available. PMID: 19153420 [PubMed - indexed for MEDLINE]Related articlesFree article

Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis.

Robey RB, Hay N.

Semin Cancer Biol. 2009 Feb;19(1):25-31. Epub 2008 Dec 14. Review.PMID: 19130886 [PubMed - indexed for MEDLINE]Related articles

Functional polymorphism of the Anpep gene increases promoter activity in the Dahl salt-resistant rat.

Kotlo K, Hughes DE, Herrera VL, Ruiz-Opazo N, Costa RH, Robey RB, Danziger RS.

Hypertension. 2007 Mar;49(3):467-72. Epub 2007 Jan 22.PMID: 17242304 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.

Robey RB, Hay N.

Oncogene. 2006 Aug 7;25(34):4683-96. Review.PMID: 16892082 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial hexokinases: guardians of the mitochondria.

Robey RB, Hay N.

Cell Cycle. 2005 May;4(5):654-8. Epub 2005 May 15.PMID: 15846094 [PubMed - indexed for MEDLINE]Related articlesFree article

Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak.

Majewski N, Nogueira V, Bhaskar P, Coy PE, Skeen JE, Gottlob K, Chandel NS, Thompson CB, Robey RB, Hay N.

Mol Cell. 2004 Dec 3;16(5):819-30.PMID: 15574336 [PubMed - indexed for MEDLINE]Related articles

Insulin-mediated activation of activator protein-1 through the mitogen-activated protein kinase pathway stimulates collagenase-1 gene transcription in the MES 13 mesangial cell line.

Ayala JE, Boustead JN, Chapman SC, Svitek CA, Oeser JK, Robey RB, O'Brien RM.

J Mol Endocrinol. 2004 Aug;33(1):263-80.PMID: 15291758 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinflammatory interleukin-1 cytokines increase mesangial cell hexokinase activity and hexokinase II isoform abundance.

Taneja N, Coy PE, Lee I, Bryson JM, Robey RB.

Am J Physiol Cell Physiol. 2004 Aug;287(2):C548-57. Epub 2004 Apr 7.PMID: 15070811 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular factors altered in glucose-treated mesangial cells and diabetic glomeruli. Changes in vascular factors impair endothelial cell growth and matrix.

Singh AK, Gudehithlu KP, Pegoraro AA, Singh GK, Basheerudin K, Robey RB, Arruda JA, Dunea G.

Lab Invest. 2004 May;84(5):597-606.PMID: 15048134 [PubMed - indexed for MEDLINE]Related articlesFree article

Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases.

Majewski N, Nogueira V, Robey RB, Hay N.

Mol Cell Biol. 2004 Jan;24(2):730-40.PMID: 14701745 [PubMed - indexed for MEDLINE]Related articlesFree article

Caveat experimentor: reporting expression profiling data involving multiple, functionally redundant isoforms.

Robey RB.

J Leukoc Biol. 2003 Sep;74(3):307-8; author reply: 309-10. No abstract available. PMID: 12949233 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of phosphatidylinositol 3-kinase (PI3K) in CO2 stimulation of the Na+/HCO3- cotransporter (NBC).

Bernardo AA, Espiritu DJ, Ruiz OS, Robey RB, Arruda JA.

J Membr Biol. 2003 Jan 15;191(2):141-8.PMID: 12533781 [PubMed - indexed for MEDLINE]Related articles

A central role for Pyk2-Src interaction in coupling diverse stimuli to increased epithelial NBC activity.

Espiritu DJ, Bernardo AA, Robey RB, Arruda JA.

Am J Physiol Renal Physiol. 2002 Oct;283(4):F663-70.PMID: 12217857 [PubMed - indexed for MEDLINE]Related articlesFree article

LPA is a novel lipid regulator of mesangial cell hexokinase activity and HKII isoform expression.

Coy PE, Taneja N, Lee I, Hecquet C, Bryson JM, Robey RB.

Am J Physiol Renal Physiol. 2002 Aug;283(2):F271-9.PMID: 12110510 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II stimulation of renal epithelial cell Na/HCO3 cotransport activity: a central role for Src family kinase/classic MAPK pathway coupling.

Robey RB, Ruiz OS, Espiritu DJ, Ibañez VC, Kear FT, Noboa OA, Bernardo AA, Arruda JA.

J Membr Biol. 2002 May 15;187(2):135-45.PMID: 12029370 [PubMed - indexed for MEDLINE]Related articles

Regulation of mesangial cell hexokinase activity and expression by heparin-binding epidermal growth factor-like growth factor: epidermal growth factors and phorbol esters increase glucose metabolism via a common mechanism involving classic mitogen-activated protein kinase pathway activation and induction of hexokinase II expression.

Robey RB, Ma J, Santos AV, Noboa OA, Coy PE, Bryson JM.

J Biol Chem. 2002 Apr 26;277(17):14370-8. Epub 2002 Jan 8.PMID: 11782486 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death.

Bryson JM, Coy PE, Gottlob K, Hay N, Robey RB.

J Biol Chem. 2002 Mar 29;277(13):11392-400. Epub 2001 Dec 18.PMID: 11751868 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase.

Gottlob K, Majewski N, Kennedy S, Kandel E, Robey RB, Hay N.

Genes Dev. 2001 Jun 1;15(11):1406-18.PMID: 11390360 [PubMed - indexed for MEDLINE]Related articlesFree article

SFKs, Ras, and the classic MAPK pathway couple muscarinic receptor activation to increased Na-HCO(3) cotransport activity in renal epithelial cells.

Robey RB, Ruiz OS, Baniqued J, Mahmud D, Espiritu DJ, Bernardo AA, Arruda JA.

Am J Physiol Renal Physiol. 2001 May;280(5):F844-50.PMID: 11292627 [PubMed - indexed for MEDLINE]Related articlesFree article

Thrombin is a novel regulator of hexokinase activity in mesangial cells.

Robey RB, Raval BJ, Ma J, Santos AV.

Kidney Int. 2000 Jun;57(6):2308-18.PMID: 10844601 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of mesangial cell hexokinase activity by PKC and the classic MAPK pathway.

Robey RB, Ma J, Santos AV.

Am J Physiol. 1999 Nov;277(5 Pt 2):F742-9.PMID: 10564237 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the renal Na-HCO(3) cotransporter. XI. Signal transduction underlying CO(2) stimulation.

Ruiz OS, Robey RB, Qiu YY, Wang LJ, Li CJ, Ma J, Arruda JA.

Am J Physiol. 1999 Oct;277(4 Pt 2):F580-6.PMID: 10516283 [PubMed - indexed for MEDLINE]Related articlesFree article

Basolateral Na(+)/HCO(3)(-) cotransport activity is regulated by the dissociable Na(+)/H(+) exchanger regulatory factor.

Bernardo AA, Kear FT, Santos AV, Ma J, Steplock D, Robey RB, Weinman EJ.

J Clin Invest. 1999 Jul;104(2):195-201.PMID: 10411549 [PubMed - indexed for MEDLINE]Related articlesFree article

pH-dependent fluorescence of a heterologously expressed Aequorea green fluorescent protein mutant: in situ spectral characteristics and applicability to intracellular pH estimation.

Robey RB, Ruiz O, Santos AV, Ma J, Kear F, Wang LJ, Li CJ, Bernardo AA, Arruda JA.

Biochemistry. 1998 Jul 14;37(28):9894-901.PMID: 9665694 [PubMed - indexed for MEDLINE]Related articles

Identification and characterization of basal and cyclic AMP response elements in the promoter of the rat hexokinase II gene.

Osawa H, Robey RB, Printz RL, Granner DK.

J Biol Chem. 1996 Jul 19;271(29):17296-303.PMID: 8663388 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin.

Osawa H, Sutherland C, Robey RB, Printz RL, Granner DK.

J Biol Chem. 1996 Jul 12;271(28):16690-4.PMID: 8663315 [PubMed - indexed for MEDLINE]Related articlesFree article

Transient gene transfer into myotubes following differentiation in culture.

Robey RB, Osawa H, Printz RL, Granner DK.

Biotechniques. 1996 Jan;20(1):40-2. No abstract available. PMID: 8770402 [PubMed - indexed for MEDLINE]Related articles

Cloning of a Na(+)- and Cl(-)-dependent betaine transporter that is regulated by hypertonicity.

Yamauchi A, Uchida S, Kwon HM, Preston AS, Robey RB, Garcia-Perez A, Burg MB, Handler JS.

J Biol Chem. 1992 Jan 5;267(1):649-52.PMID: 1370453 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of glycinebetaine uptake into Xenopus oocytes by injection of poly(A)+ RNA from renal cells exposed to high extracellular NaCl.

Robey RB, Kwon HM, Handler JS, Garcia-Perez A, Burg MB.

J Biol Chem. 1991 Jun 5;266(16):10400-5.PMID: 2037590 [PubMed - indexed for MEDLINE]Related articlesFree article

Renal Na-myo-inositol cotransporter mRNA expression in Xenopus oocytes: regulation by hypertonicity.

Kwon HM, Yamauchi A, Uchida S, Robey RB, Garcia-Perez A, Burg MB, Handler JS.

Am J Physiol. 1991 Feb;260(2 Pt 2):F258-63.PMID: 1996676 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid induction of beta-adrenergic receptors in the DDT1 MF-2 smooth muscle cell line involves synthesis of new receptor.

Norris JS, Brown P, Cohen J, Cornett LE, Kohler PO, MacLeod SL, Popovich K, Robey RB, Sifford M, Syms AJ, et al.

Mol Cell Biochem. 1987 Mar;74(1):21-7.PMID: 3035362 [PubMed - indexed for MEDLINE]Related articles