PubMed

B cells suppress the inflammatory response in a mouse model of primary biliary cirrhosis.

Moritoki Y, Zhang W, Tsuneyama K, Yoshida K, Wakabayashi K, Yang GX, Bowlus C, Ridgway WM, Ueno Y, Ansari AA, Coppel RL, Mackay IR, Flavell RA, Gershwin ME, Lian ZX.

Gastroenterology. 2009 Mar;136(3):1037-47. Epub 2008 Nov 19.PMID: 19118554 [PubMed - indexed for MEDLINE]Related articles

Gene-gene interactions in the NOD mouse model of type 1 diabetes.

Ridgway WM, Peterson LB, Todd JA, Rainbow DB, Healy B, Burren OS, Wicker LS.

Adv Immunol. 2008;100:151-75. Review.PMID: 19111166 [PubMed - indexed for MEDLINE]Related articles

Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization.

Wakabayashi K, Yoshida K, Leung PS, Moritoki Y, Yang GX, Tsuneyama K, Lian ZX, Hibi T, Ansari AA, Wicker LS, Ridgway WM, Coppel RL, Mackay IR, Gershwin ME.

Clin Exp Immunol. 2009 Mar;155(3):577-86. Epub 2008 Dec 15.PMID: 19094117 [PubMed - indexed for MEDLINE]Related articles

Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Ralpha(-/-) mice.

Hsu W, Zhang W, Tsuneyama K, Moritoki Y, Ridgway WM, Ansari AA, Coppel RL, Lian ZX, Mackay I, Gershwin ME.

Hepatology. 2009 Jan;49(1):133-40.PMID: 19065673 [PubMed - indexed for MEDLINE]Related articles

Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease.

Wakabayashi K, Lian ZX, Leung PS, Moritoki Y, Tsuneyama K, Kurth MJ, Lam KS, Yoshida K, Yang GX, Hibi T, Ansari AA, Ridgway WM, Coppel RL, Mackay IR, Gershwin ME.

Hepatology. 2008 Aug;48(2):531-40.PMID: 18563844 [PubMed - indexed for MEDLINE]Related articles

Liver autoimmunity triggered by microbial activation of natural killer T cells.

Mattner J, Savage PB, Leung P, Oertelt SS, Wang V, Trivedi O, Scanlon ST, Pendem K, Teyton L, Hart J, Ridgway WM, Wicker LS, Gershwin ME, Bendelac A.

Cell Host Microbe. 2008 May 15;3(5):304-15.PMID: 18474357 [PubMed - indexed for MEDLINE]Related articlesFree article

Animal models of primary biliary cirrhosis.

Chuang YH, Ridgway WM, Ueno Y, Gershwin ME.

Clin Liver Dis. 2008 May;12(2):333-47; ix. Review.PMID: 18456184 [PubMed - indexed for MEDLINE]Related articlesFree article

Adoptive transfer of CD8(+) T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice.

Yang GX, Lian ZX, Chuang YH, Moritoki Y, Lan RY, Wakabayashi K, Ansari AA, Flavell RA, Ridgway WM, Coppel RL, Tsuneyama K, Mackay IR, Gershwin ME.

Hepatology. 2008 Jun;47(6):1974-82.PMID: 18452147 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide microarray expression analysis of CD4+ T Cells from nonobese diabetic congenic mice identifies Cd55 (Daf1) and Acadl as candidate genes for type 1 diabetes.

Irie J, Reck B, Wu Y, Wicker LS, Howlett S, Rainbow D, Feingold E, Ridgway WM.

J Immunol. 2008 Jan 15;180(2):1071-9.PMID: 18178847 [PubMed - indexed for MEDLINE]Related articlesFree article

Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis.

Chuang YH, Lian ZX, Yang GX, Shu SA, Moritoki Y, Ridgway WM, Ansari AA, Kronenberg M, Flavell RA, Gao B, Gershwin ME.

Hepatology. 2008 Feb;47(2):571-80.PMID: 18098320 [PubMed - indexed for MEDLINE]Related articles

Murine models of primary biliary cirrhosis: Comparisons and contrasts.

Oertelt S, Ridgway WM, Ansari AA, Coppel RL, Gershwin ME.

Hepatol Res. 2007 Oct;37 Suppl 3:S365-9.PMID: 17931188 [PubMed - in process]Related articles

Species-specific immune responses generated by histidyl-tRNA synthetase immunization are associated with muscle and lung inflammation.

Katsumata Y, Ridgway WM, Oriss T, Gu X, Chin D, Wu Y, Fertig N, Oury T, Vandersteen D, Clemens P, Camacho CJ, Weinberg A, Ascherman DP.

J Autoimmun. 2007 Sep-Nov;29(2-3):174-86.PMID: 17826948 [PubMed - indexed for MEDLINE]Related articlesFree article

New tools for defining the 'genetic background' of inbred mouse strains.

Ridgway WM, Healy B, Smink LJ, Rainbow D, Wicker LS.

Nat Immunol. 2007 Jul;8(7):669-73. Review. No abstract available. PMID: 17579641 [PubMed - indexed for MEDLINE]Related articles

Autoimmune cholangitis in NOD.c3c4 mice is associated with cholangiocyte-specific Fas antigen deficiency.

Nakagome Y, Ueno Y, Kogure T, Fukushima K, Moritoki Y, Ridgway WM, Eric Gershwin M, Shimosegawa T.

J Autoimmun. 2007 Aug;29(1):20-9. Epub 2007 May 7.PMID: 17482429 [PubMed - indexed for MEDLINE]Related articles

Dissecting genetic control of autoimmunity in NOD congenic mice.

Ridgway WM.

Immunol Res. 2006;36(1-3):189-95. Review.PMID: 17337779 [PubMed - indexed for MEDLINE]Related articles

Modulating protective and pathogenic CD4+ subsets via CD137 in type 1 diabetes.

Irie J, Wu Y, Kachapati K, Mittler RS, Ridgway WM.

Diabetes. 2007 Jan;56(1):186-96.PMID: 17192481 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice.

Oertelt S, Lian ZX, Cheng CM, Chuang YH, Padgett KA, He XS, Ridgway WM, Ansari AA, Coppel RL, Li MO, Flavell RA, Kronenberg M, Mackay IR, Gershwin ME.

J Immunol. 2006 Aug 1;177(3):1655-60.PMID: 16849474 [PubMed - indexed for MEDLINE]Related articlesFree article

New insights to the immunopathology and autoimmune responses in primary biliary cirrhosis.

He XS, Ansari AA, Ridgway WM, Coppel RL, Gershwin ME.

Cell Immunol. 2006 Jan;239(1):1-13. Review.PMID: 16765923 [PubMed - indexed for MEDLINE]Related articles

NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis.

Irie J, Wu Y, Wicker LS, Rainbow D, Nalesnik MA, Hirsch R, Peterson LB, Leung PS, Cheng C, Mackay IR, Gershwin ME, Ridgway WM.

J Exp Med. 2006 May 15;203(5):1209-19. Epub 2006 Apr 24.PMID: 16636131 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic control of anti-Sm autoantibody production in NOD congenic mice narrowed to the Idd9.3 region.

Irie J, Wu Y, Sass DA, Ridgway WM.

Immunogenetics. 2006 Feb;58(1):9-14. Epub 2006 Jan 27.PMID: 16425035 [PubMed - indexed for MEDLINE]Related articles

A modular theory of autoimmunity.

Irie J, Ridgway WM.

Keio J Med. 2005 Sep;54(3):121-6. Review.PMID: 16237273 [PubMed - indexed for MEDLINE]Related articlesFree article

NOD mice and autoimmunity.

Aoki CA, Borchers AT, Ridgway WM, Keen CL, Ansari AA, Gershwin ME.

Autoimmun Rev. 2005 Jul;4(6):373-9. Epub 2005 Mar 29. Review.PMID: 16081028 [PubMed - indexed for MEDLINE]Related articles

Nonobese diabetic CD4 lymphocytosis maps outside the MHC locus on chromosome 17.

Koarada S, Wu Y, Yim YS, Wakeland EW, Ridgway WM.

Immunogenetics. 2004 Aug;56(5):333-7. Epub 2004 Aug 12.PMID: 15309345 [PubMed - indexed for MEDLINE]Related articles

Genetic control of autoimmunity: protection from diabetes, but spontaneous autoimmune biliary disease in a nonobese diabetic congenic strain.

Koarada S, Wu Y, Fertig N, Sass DA, Nalesnik M, Todd JA, Lyons PA, Fenyk-Melody J, Rainbow DB, Wicker LS, Peterson LB, Ridgway WM.

J Immunol. 2004 Aug 15;173(4):2315-23.PMID: 15294944 [PubMed - indexed for MEDLINE]Related articlesFree article

The non obese diabetic (NOD) mouse: a unique model for understanding the interaction between genetics and T cell responses.

Ridgway WM.

Rev Endocr Metab Disord. 2003 Sep;4(3):263-9. Review. No abstract available. PMID: 14501177 [PubMed - indexed for MEDLINE]Related articles

Increased nonobese diabetic Th1:Th2 (IFN-gamma:IL-4) ratio is CD4+ T cell intrinsic and independent of APC genetic background.

Koarada S, Wu Y, Olshansky G, Ridgway WM.

J Immunol. 2002 Dec 1;169(11):6580-7.PMID: 12444170 [PubMed - indexed for MEDLINE]Related articlesFree article

Understanding the interaction of genetics and cellular responses in nonobese diabetic mice.

Ridgway WM, Fathman CG.

Curr Dir Autoimmun. 2001;4:218-38. Review. No abstract available. PMID: 11569404 [PubMed - indexed for MEDLINE]Related articles

Increased entry into the IFN-gamma effector pathway by CD4+ T cells selected by I-Ag7 on a nonobese diabetic versus C57BL/6 genetic background.

Koarada S, Wu Y, Ridgway WM.

J Immunol. 2001 Aug 1;167(3):1693-702.PMID: 11466393 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo.

Fassò M, Anandasabapathy N, Crawford F, Kappler J, Fathman CG, Ridgway WM.

J Exp Med. 2000 Dec 18;192(12):1719-30.PMID: 11120769 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and characterization of the antigen-specific subpopulation of alloreactive CD4+ T cells in vitro and in vivo.

Krieger NR, Fathman CG, Shaw MK, Ridgway WM.

Transplantation. 2000 Feb 27;69(4):605-9.PMID: 10708118 [PubMed - indexed for MEDLINE]Related articles

MHC structure and autoimmune T cell repertoire development.

Ridgway WM, Fathman CG.

Curr Opin Immunol. 1999 Dec;11(6):638-42. Review.PMID: 10631548 [PubMed - indexed for MEDLINE]Related articles

A new look at MHC and autoimmune disease.

Ridgway WM, Fassò M, Fathman CG.

Science. 1999 Apr 30;284(5415):749, 751. No abstract available. PMID: 10336398 [PubMed - indexed for MEDLINE]Related articles

Analysis of the role of variation of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response.

Ridgway WM, Ito H, Fassò M, Yu C, Fathman CG.

J Exp Med. 1998 Dec 21;188(12):2267-75.PMID: 9858513 [PubMed - indexed for MEDLINE]Related articlesFree article

The association of MHC with autoimmune diseases: understanding the pathogenesis of autoimmune diabetes.

Ridgway WM, Fathman CG.

Clin Immunol Immunopathol. 1998 Jan;86(1):3-10. Review.PMID: 9434791 [PubMed - indexed for MEDLINE]Related articles

Breaking self-tolerance in nonobese diabetic mice.

Ridgway WM, Fassò M, Lanctot A, Garvey C, Fathman CG.

J Exp Med. 1996 Apr 1;183(4):1657-62.PMID: 8666923 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of autoimmune response.

Ridgway WM, Weiner HL, Fathman CG.

Curr Opin Immunol. 1994 Dec;6(6):946-55. Review.PMID: 7710719 [PubMed - indexed for MEDLINE]Related articles

Aggressive drug therapy for rheumatoid arthritis.

McGuire JL, Ridgway WM.

Hosp Pract (Off Ed). 1993 Sep 15;28(9):45-52.PMID: 8366157 [PubMed - indexed for MEDLINE]Related articles