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    Results: 49

    1.

    Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.

    Kotronen A, Peltonen M, Hakkarainen A, Sevastianova K, Bergholm R, Johansson LM, Lundbom N, Rissanen A, Ridderstråle M, Groop L, Orho-Melander M, Yki-Järvinen H.

    Gastroenterology. 2009 Sep;137(3):865-72. Epub 2009 Jun 12.PMID: 19524579 [PubMed - indexed for MEDLINE]Related articles

    2.

    Genetic variance in the adiponutrin gene family and childhood obesity.

    Johansson LE, Johansson LM, Danielsson P, Norgren S, Johansson S, Marcus C, Ridderstråle M.

    PLoS One. 2009;4(4):e5327. Epub 2009 Apr 24.PMID: 19390624 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans.

    Kotronen A, Johansson LE, Johansson LM, Roos C, Westerbacka J, Hamsten A, Bergholm R, Arkkila P, Arola J, Kiviluoto T, Fisher RM, Ehrenborg E, Orho-Melander M, Ridderstråle M, Groop L, Yki-Järvinen H.

    Diabetologia. 2009 Jun;52(6):1056-60. Epub 2009 Feb 18.PMID: 19224197 [PubMed - indexed for MEDLINE]Related articles

    4.

    Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

    Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstråle M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N; Wellcome Trust Case Control Consortium, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN; Genetic Investigation of ANthropometric Traits Consortium.

    Nat Genet. 2009 Jan;41(1):25-34. Epub 2008 Dec 14.PMID: 19079261 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in men.

    Ingelsson E, Bennet L, Ridderstråle M, Söderström M, Råstam L, Lindblad U.

    BMC Cardiovasc Disord. 2008 Dec 11;8:37.PMID: 19077249 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Genetic dissection of type 2 diabetes.

    Ridderstråle M, Groop L.

    Mol Cell Endocrinol. 2009 Jan 15;297(1-2):10-7. Epub 2008 Oct 19. Review.PMID: 19000735 [PubMed - indexed for MEDLINE]Related articles

    7.

    The visfatin (PBEF1) G-948T gene polymorphism is associated with increased high-density lipoprotein cholesterol in obese subjects.

    Johansson LM, Johansson LE, Ridderstråle M.

    Metabolism. 2008 Nov;57(11):1558-62.PMID: 18940394 [PubMed - indexed for MEDLINE]Related articles

    8.

    Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents.

    Jacobsson JA, Klovins J, Kapa I, Danielsson P, Svensson V, Ridderstråle M, Gyllensten U, Marcus C, Fredriksson R, Schiöth HB.

    Int J Obes (Lond). 2008 Nov;32(11):1730-5. Epub 2008 Sep 16.PMID: 18794893 [PubMed - indexed for MEDLINE]Related articles

    9.

    Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity.

    Johansson LE, Lindblad U, Larsson CA, Råstam L, Ridderstråle M.

    Eur J Endocrinol. 2008 Nov;159(5):577-83. Epub 2008 Aug 26. Erratum in: Eur J Endocrinol. 2008 Dec;159(6):843. PMID: 18728122 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Interaction between PPARG Pro12Ala and ADIPOQ G276T concerning cholesterol levels in childhood obesity.

    Johansson LE, Danielsson P, Norgren S, Marcus C, Ridderstråle M.

    Int J Pediatr Obes. 2009;4(2):119-25.PMID: 18645733 [PubMed - indexed for MEDLINE]Related articles

    11.

    [Reply on new drugs against type 2 diabetes: important to gain experience and knowledge]

    Sjöholm A, Agardh CD, Brismar K, Efendic S, Eliasson B, Eriksson JW, Frid A, Groop L, Holmgren J, Ridderstråle M, Smith U.

    Lakartidningen. 2008 Apr 23-May 6;105(17-18):1310, 1312. Swedish. No abstract available. PMID: 18561535 [PubMed - indexed for MEDLINE]Related articles

    12.

    Common variants near MC4R are associated with fat mass, weight and risk of obesity.

    Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI; Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Sadaf Farooqi I, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM; KORA, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Jarvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L; Nurses' Health Study, Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK; Diabetes Genetics Initiative, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M; SardiNIA Study, Vogel CI, Wallace C, Waterworth DM, Weedon MN; Wellcome Trust Case Control Consortium, Willer CJ; FUSION, Wraight, Yuan X, Zeggini E, Hirschhorn JN, Strachan DP, Ouwehand WH, Caulfield MJ, Samani NJ, Frayling TM, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy MI, Wareham NJ, Barroso I, Jacobs KB, Chanock SJ, Hayes RB, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Kraft P, Hankinson SE, Hunter DJ, Hu FB, Lyon HN, Voight BF, Ridderstrale M, Groop L, Scheet P, Sanna S, Abecasis GR, Albai G, Nagaraja R, Schlessinger D, Jackson AU, Tuomilehto J, Collins FS, Boehnke M, Mohlke KL.

    Nat Genet. 2008 Jun;40(6):768-75. Epub 2008 May 4.PMID: 18454148 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Type 2 diabetes candidate gene CAPN10: first, but not last.

    Ridderstråle M, Nilsson E.

    Curr Hypertens Rep. 2008 Feb;10(1):19-24.PMID: 18367022 [PubMed - indexed for MEDLINE]Related articles

    14.

    Expression of the transcription factor 7-like 2 gene (TCF7L2) in human adipocytes is down regulated by insulin.

    Ahlzén M, Johansson LE, Cervin C, Tornqvist H, Groop L, Ridderstråle M.

    Biochem Biophys Res Commun. 2008 May 23;370(1):49-52. Epub 2008 Mar 13.PMID: 18342627 [PubMed - indexed for MEDLINE]Related articles

    15.

    The P2Y 13 Met-158-Thr polymorphism, which is in linkage disequilibrium with the P2Y 12 locus, is not associated with acute myocardial infarction.

    Amisten S, Braun OO, Johansson L, Ridderstråle M, Melander O, Erlinge D.

    PLoS One. 2008 Jan 23;3(1):e1462.PMID: 18213371 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Regulation of skeletal muscle PPAR delta mRNA expression in twins.

    Nilsson E, Poulsen P, Sjögren M, Ling C, Ridderstråle M, Groop L, Vaag A.

    J Physiol. 2007 Nov 1;584(Pt 3):1011-7. Epub 2007 Sep 13.PMID: 17855759 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    TXNIP regulates peripheral glucose metabolism in humans.

    Parikh H, Carlsson E, Chutkow WA, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Jensen CB, Krook A, Björnholm M, Tornqvist H, Zierath JR, Ridderstråle M, Altshuler D, Lee RT, Vaag A, Groop LC, Mootha VK.

    PLoS Med. 2007 May;4(5):e158.PMID: 17472435 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Thyrostimulin (a TSH-like Hormone) expression in orbital and thyroid tissue.

    Lantz M, Vondrichova T, Capretz A, Nilsson E, Frenander C, Bondeson AG, Ridderstråle M, Aberg M, Asman P, Groop L, Hallengren B.

    Thyroid. 2007 Feb;17(2):113-8.PMID: 17316112 [PubMed - indexed for MEDLINE]Related articles

    19.

    The hormone-sensitive lipase C-60G promoter polymorphism is associated with increased waist circumference in normal-weight subjects.

    Carlsson E, Johansson LE, Ström K, Hoffstedt J, Groop L, Holm C, Ridderstråle M.

    Int J Obes (Lond). 2006 Sep;30(9):1442-8. Epub 2006 Mar 14.PMID: 16534522 [PubMed - indexed for MEDLINE]Related articles

    20.

    Variation in the adiponutrin gene influences its expression and associates with obesity.

    Johansson LE, Hoffstedt J, Parikh H, Carlsson E, Wabitsch M, Bondeson AG, Hedenbro J, Tornqvist H, Groop L, Ridderstråle M.

    Diabetes. 2006 Mar;55(3):826-33.PMID: 16505250 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Obesity and cardiovascular risk factors in type 2 diabetes: results from the Swedish National Diabetes Register.

    Ridderstråle M, Gudbjörnsdottir S, Eliasson B, Nilsson PM, Cederholm J; Steering Committee of the Swedish National Diabetes Register (NDR).

    J Intern Med. 2006 Mar;259(3):314-22.PMID: 16476109 [PubMed - indexed for MEDLINE]Related articles

    22.

    Increased risk of obesity associated with the variant allele of the PPARGC1A Gly482Ser polymorphism in physically inactive elderly men.

    Ridderstråle M, Johansson LE, Rastam L, Lindblad U.

    Diabetologia. 2006 Mar;49(3):496-500. Epub 2006 Feb 9.PMID: 16474966 [PubMed - indexed for MEDLINE]Related articles

    23.

    A polymorphism in the adiponectin gene influences adiponectin expression levels in visceral fat in obese subjects.

    Fredriksson J, Carlsson E, Orho-Melander M, Groop L, Ridderstråle M.

    Int J Obes (Lond). 2006 Feb;30(2):226-32.PMID: 16231017 [PubMed - indexed for MEDLINE]Related articles

    24.

    Genetic and nongenetic regulation of CAPN10 mRNA expression in skeletal muscle.

    Carlsson E, Poulsen P, Storgaard H, Almgren P, Ling C, Jensen CB, Madsbad S, Groop L, Vaag A, Ridderstråle M.

    Diabetes. 2005 Oct;54(10):3015-20.PMID: 16186407 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Calpain 10 and type 2 diabetes: are we getting closer to an explanation?

    Ridderstråle M, Parikh H, Groop L.

    Curr Opin Clin Nutr Metab Care. 2005 Jul;8(4):361-6. Review.PMID: 15930958 [PubMed - indexed for MEDLINE]Related articles

    26.

    Overexpression of immediate early genes in active Graves' ophthalmopathy.

    Lantz M, Vondrichova T, Parikh H, Frenander C, Ridderstråle M, Asman P, Aberg M, Groop L, Hallengren B.

    J Clin Endocrinol Metab. 2005 Aug;90(8):4784-91. Epub 2005 May 31.PMID: 15928252 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    Signaling mechanism for the insulin-like effects of growth hormone--another example of a classical hormonal negative feedback loop.

    Ridderstråle M.

    Curr Drug Targets Immune Endocr Metabol Disord. 2005 Mar;5(1):79-92. Review.PMID: 15777207 [PubMed - indexed for MEDLINE]Related articles

    28.

    The FOXC2 C-512T polymorphism is associated with obesity and dyslipidemia.

    Carlsson E, Almgren P, Hoffstedt J, Groop L, Ridderstråle M.

    Obes Res. 2004 Nov;12(11):1738-43.PMID: 15601967 [PubMed - indexed for MEDLINE]Related articles

    29.

    Role of the FOXC2 -512C>T polymorphism in type 2 diabetes: possible association with the dysmetabolic syndrome.

    Carlsson E, Groop L, Ridderstråle M.

    Int J Obes (Lond). 2005 Mar;29(3):268-74.PMID: 15597109 [PubMed - indexed for MEDLINE]Related articles

    30.

    Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins.

    Ling C, Poulsen P, Carlsson E, Ridderstråle M, Almgren P, Wojtaszewski J, Beck-Nielsen H, Groop L, Vaag A.

    J Clin Invest. 2004 Nov;114(10):1518-26.PMID: 15546003 [PubMed - indexed for MEDLINE]Related articlesFree article

    31.

    Variation in the calpain-10 gene is associated with elevated triglyceride levels and reduced adipose tissue messenger ribonucleic acid expression in obese Swedish subjects.

    Carlsson E, Fredriksson J, Groop L, Ridderstråle M.

    J Clin Endocrinol Metab. 2004 Jul;89(7):3601-5.PMID: 15240652 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Characterization of the human skeletal muscle glycogen synthase gene (GYS1) promoter.

    Fredriksson J, Ridderstråle M, Groop L, Orho-Melander M.

    Eur J Clin Invest. 2004 Feb;34(2):113-21.PMID: 14764074 [PubMed - indexed for MEDLINE]Related articles

    33.

    The SLC6A14 gene shows evidence of association with obesity.

    Suviolahti E, Oksanen LJ, Ohman M, Cantor RM, Ridderstrale M, Tuomi T, Kaprio J, Rissanen A, Mustajoki P, Jousilahti P, Vartiainen E, Silander K, Kilpikari R, Salomaa V, Groop L, Kontula K, Peltonen L, Pajukanta P.

    J Clin Invest. 2003 Dec;112(11):1762-72.PMID: 14660752 [PubMed - indexed for MEDLINE]Related articlesFree article

    34.

    Pro-opiomelanocortin gene is associated with serum leptin levels in lean but not in obese individuals.

    Suviolahti E, Ridderstråle M, Almgren P, Klannemark M, Melander O, Carlsson E, Carlsson M, Hedenbro J, Orho-Melander M.

    Int J Obes Relat Metab Disord. 2003 Oct;27(10):1204-11.PMID: 14513068 [PubMed - indexed for MEDLINE]Related articles

    35.

    PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

    Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC.

    Nat Genet. 2003 Jul;34(3):267-73.PMID: 12808457 [PubMed - indexed for MEDLINE]Related articles

    36.

    SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling.

    Ridderstråle M, Amstrup J, Hilton DJ, Billestrup N, Tornqvist H.

    Horm Metab Res. 2003 Mar;35(3):169-77.PMID: 12734778 [PubMed - indexed for MEDLINE]Related articles

    37.

    Characterization of a naturally occurring mutation (L107I) in the HNF1 alpha (MODY3) gene.

    Cervin C, Orho-Melander M, Ridderstråle M, Lehto M, Barg S, Groop L, Cilio CM.

    Diabetologia. 2002 Dec;45(12):1703-8. Epub 2002 Oct 19.PMID: 12488960 [PubMed - indexed for MEDLINE]Related articles

    38.

    FOXC2 mRNA Expression and a 5' untranslated region polymorphism of the gene are associated with insulin resistance.

    Ridderstråle M, Carlsson E, Klannemark M, Cederberg A, Kösters C, Tornqvist H, Storgaard H, Vaag A, Enerbäck S, Groop L.

    Diabetes. 2002 Dec;51(12):3554-60.PMID: 12453913 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels.

    Orho-Melander M, Klannemark M, Svensson MK, Ridderstråle M, Lindgren CM, Groop L.

    Diabetes. 2002 Aug;51(8):2658-64. Erratum in: Diabetes. 2003 May;52(5):1306. PMID: 12145185 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    [A case report. Rosiglitazone treatment was highly effective yet had to be terminated]

    Ridderstråle M, Groop L.

    Lakartidningen. 2002 Jan 31;99(5):407-10. Swedish. PMID: 11881246 [PubMed - indexed for MEDLINE]Related articles

    41.

    Differential phosphorylation of Janus kinase 2, Stat5A and Stat5B in response to growth hormone in primary rat adipocytes.

    Ridderstråle M, Groop L.

    Mol Cell Endocrinol. 2001 Oct 25;183(1-2):49-54.PMID: 11604224 [PubMed - indexed for MEDLINE]Related articles

    43.

    Tyrosine phosphorylation of the growth hormone (GH) receptor and Janus tyrosine kinase-2 is involved in the insulin-like actions of GH in primary rat adipocytes.

    Eriksson H, Ridderstråle M, Tornqvist H.

    Endocrinology. 1995 Nov;136(11):5093-101.PMID: 7588246 [PubMed - indexed for MEDLINE]Related articles

    44.

    The acute insulin-like effects of growth hormone in primary adipocyte-signaling mechanisms.

    Tornqvist H, Ridderstråle M, Eriksson H, Degerman E.

    Ann N Y Acad Sci. 1995 Sep 7;766:469-71. No abstract available. PMID: 7486694 [PubMed - indexed for MEDLINE]Related articles

    45.

    Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin.

    Eriksson H, Ridderstråle M, Degerman E, Ekholm D, Smith CJ, Manganiello VC, Belfrage P, Tornqvist H.

    Biochim Biophys Acta. 1995 Apr 6;1266(1):101-7.PMID: 7718614 [PubMed - indexed for MEDLINE]Related articles

    47.

    PI-3-kinase inhibitor Wortmannin blocks the insulin-like effects of growth hormone in isolated rat adipocytes.

    Ridderstråle M, Tornqvist H.

    Biochem Biophys Res Commun. 1994 Aug 30;203(1):306-10.PMID: 8074671 [PubMed - indexed for MEDLINE]Related articles

    48.

    Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes. Studies using the selective inhibitor wortmannin.

    Rahn T, Ridderstråle M, Tornqvist H, Manganiello V, Fredrikson G, Belfrage P, Degerman E.

    FEBS Lett. 1994 Aug 22;350(2-3):314-8.PMID: 8070584 [PubMed - indexed for MEDLINE]Related articles

    49.

    cAMP-dependent protein kinase activation mediated by beta 3-adrenergic receptors parallels lipolysis in rat adipocytes.

    Langin D, Ekholm D, Ridderstråle M, Lafontan M, Belfrage P.

    Biochim Biophys Acta. 1992 Jun 29;1135(3):349-52.PMID: 1352466 [PubMed - indexed for MEDLINE]Related articles

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