PubMed

Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods.

Pfaller MA, Diekema DJ, Ghannoum MA, Rex JH, Alexander BD, Andes D, Brown SD, Chaturvedi V, Espinel-Ingroff A, Fowler CL, Johnson EM, Knapp CC, Motyl MR, Ostrosky-Zeichner L, Sheehan DJ, Walsh TJ; Clinical and Laboratory Standards Institute Antifungal Testing Subcommittee.

J Clin Microbiol. 2009 Oct;47(10):3142-6. Epub 2009 Aug 19.PMID: 19692559 [PubMed - in process]Related articles

Lack of correlation of 24- vs. 48-h itraconazole minimum inhibitory concentrations with microbiological and survival outcomes in a guinea pig model of disseminated candidiasis.

Odabasi Z, Paetznick VL, Rodriguez JR, Chen E, Rex JH, Leitz GJ, Ostrosky-Zeichner L.

Mycoses. 2009 Jun 4. [Epub ahead of print]PMID: 19500259 [PubMed - as supplied by publisher]Related articles

Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.

Pappas PG, Kauffman CA, Andes D, Benjamin DK Jr, Calandra TF, Edwards JE Jr, Filler SG, Fisher JF, Kullberg BJ, Ostrosky-Zeichner L, Reboli AC, Rex JH, Walsh TJ, Sobel JD; Infectious Diseases Society of America.

Clin Infect Dis. 2009 Mar 1;48(5):503-35.PMID: 19191635 [PubMed - indexed for MEDLINE]Related articles

Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method.

Ostrosky-Zeichner L, Rex JH, Pfaller MA, Diekema DJ, Alexander BD, Andes D, Brown SD, Chaturvedi V, Ghannoum MA, Knapp CC, Sheehan DJ, Walsh TJ.

Antimicrob Agents Chemother. 2008 Nov;52(11):4175-7. Epub 2008 Sep 22.PMID: 18809944 [PubMed - indexed for MEDLINE]Related articlesFree article

Empirical fluconazole versus placebo for intensive care unit patients: a randomized trial.

Schuster MG, Edwards JE Jr, Sobel JD, Darouiche RO, Karchmer AW, Hadley S, Slotman G, Panzer H, Biswas P, Rex JH.

Ann Intern Med. 2008 Jul 15;149(2):83-90.PMID: 18626047 [PubMed - indexed for MEDLINE]Related articlesFree article

Correlation of MIC with outcome for Candida species tested against caspofungin, anidulafungin, and micafungin: analysis and proposal for interpretive MIC breakpoints.

Pfaller MA, Diekema DJ, Ostrosky-Zeichner L, Rex JH, Alexander BD, Andes D, Brown SD, Chaturvedi V, Ghannoum MA, Knapp CC, Sheehan DJ, Walsh TJ.

J Clin Microbiol. 2008 Aug;46(8):2620-9. Epub 2008 Jun 25.PMID: 18579718 [PubMed - indexed for MEDLINE]Related articlesFree article

Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei.

Chaturvedi V, Ramani R, Ghannoum MA, Killian SB, Holliday N, Knapp C, Ostrosky-Zeichner L, Messer SA, Pfaller MA, Iqbal NJ, Arthington-Skaggs BA, Vazquez JA, Sein T, Rex JH, Walsh TJ.

Antimicrob Agents Chemother. 2008 Apr;52(4):1500-2. Epub 2008 Jan 28.PMID: 18227180 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of serum on in vitro susceptibility testing of echinocandins.

Odabasi Z, Paetznick V, Rex JH, Ostrosky-Zeichner L.

Antimicrob Agents Chemother. 2007 Nov;51(11):4214-6. Epub 2007 Sep 4.PMID: 17785512 [PubMed - indexed for MEDLINE]Related articlesFree article

Does one voriconazole breakpoint suit all Candida species?

Arendrup MC, Denning DW, Pfaller MA, Diekema DJ, Rex JH.

J Clin Microbiol. 2007 Jun;45(6):2093; author reply 2094. No abstract available. PMID: 17548458 [PubMed - indexed for MEDLINE]Related articlesFree article

Multicenter retrospective development and validation of a clinical prediction rule for nosocomial invasive candidiasis in the intensive care setting.

Ostrosky-Zeichner L, Sable C, Sobel J, Alexander BD, Donowitz G, Kan V, Kauffman CA, Kett D, Larsen RA, Morrison V, Nucci M, Pappas PG, Bradley ME, Major S, Zimmer L, Wallace D, Dismukes WE, Rex JH.

Eur J Clin Microbiol Infect Dis. 2007 Apr;26(4):271-6.PMID: 17333081 [PubMed - indexed for MEDLINE]Related articles

Galactomannan and the diagnosis of invasive aspergillosis.

Rex JH.

Clin Infect Dis. 2006 May 15;42(10):1428-30. Epub 2006 Apr 14. No abstract available. PMID: 16619155 [PubMed - indexed for MEDLINE]Related articles

Antifungal prophylaxis in the intensive care unit: who should get it?

Rex JH.

Crit Care Med. 2006 Apr;34(4):1286-7. No abstract available. PMID: 16550099 [PubMed - indexed for MEDLINE]Related articles

Correlation of MIC with outcome for Candida species tested against voriconazole: analysis and proposal for interpretive breakpoints.

Pfaller MA, Diekema DJ, Rex JH, Espinel-Ingroff A, Johnson EM, Andes D, Chaturvedi V, Ghannoum MA, Odds FC, Rinaldi MG, Sheehan DJ, Troke P, Walsh TJ, Warnock DW.

J Clin Microbiol. 2006 Mar;44(3):819-26.PMID: 16517860 [PubMed - indexed for MEDLINE]Related articlesFree article

Candida in the peritoneum: passenger or pathogen?

Rex JH.

Crit Care Med. 2006 Mar;34(3):902-3. No abstract available. PMID: 16505676 [PubMed - indexed for MEDLINE]Related articles

International, open-label, noncomparative, clinical trial of micafungin alone and in combination for treatment of newly diagnosed and refractory candidemia.

Ostrosky-Zeichner L, Kontoyiannis D, Raffalli J, Mullane KM, Vazquez J, Anaissie EJ, Lipton J, Jacobs P, van Rensburg JH, Rex JH, Lau W, Facklam D, Buell DN.

Eur J Clin Microbiol Infect Dis. 2005 Oct;24(10):654-61. Erratum in: Eur J Clin Microbiol Infect Dis. 2006 Jan;25(1):69. PMID: 16261306 [PubMed - indexed for MEDLINE]Related articles

Voriconazole versus a regimen of amphotericin B followed by fluconazole for candidaemia in non-neutropenic patients: a randomised non-inferiority trial.

Kullberg BJ, Sobel JD, Ruhnke M, Pappas PG, Viscoli C, Rex JH, Cleary JD, Rubinstein E, Church LW, Brown JM, Schlamm HT, Oborska IT, Hilton F, Hodges MR.

Lancet. 2005 Oct 22-28;366(9495):1435-42.PMID: 16243088 [PubMed - indexed for MEDLINE]Related articles

Invasive candidiasis in immunocompromised hospitalized patients.

Sims CR, Ostrosky-Zeichner L, Rex JH.

Arch Med Res. 2005 Nov-Dec;36(6):660-71. Review.PMID: 16216647 [PubMed - indexed for MEDLINE]Related articles

Syscan3, a kit for detection of anti-Candida antibodies for diagnosis of invasive candidiasis.

Philip A, Odabasi Z, Matiuzzi G, Paetznick VL, Tan SW, Warmington J, Rex JH, Ostrosky-Zeichner L.

J Clin Microbiol. 2005 Sep;43(9):4834-5.PMID: 16145152 [PubMed - indexed for MEDLINE]Related articlesFree article

Multicenter clinical evaluation of the (1-->3) beta-D-glucan assay as an aid to diagnosis of fungal infections in humans.

Ostrosky-Zeichner L, Alexander BD, Kett DH, Vazquez J, Pappas PG, Saeki F, Ketchum PA, Wingard J, Schiff R, Tamura H, Finkelman MA, Rex JH.

Clin Infect Dis. 2005 Sep 1;41(5):654-9. Epub 2005 Jul 21.PMID: 16080087 [PubMed - indexed for MEDLINE]Related articles

In vitro synergy testing of anidulafungin with itraconazole, voriconazole, and amphotericin B against Aspergillus spp. and Fusarium spp.

Philip A, Odabasi Z, Rodriguez J, Paetznick VL, Chen E, Rex JH, Ostrosky-Zeichner L.

Antimicrob Agents Chemother. 2005 Aug;49(8):3572-4.PMID: 16048988 [PubMed - indexed for MEDLINE]Related articlesFree article

Rules for identifying patients at increased risk for candidal infections in the surgical intensive care unit: approach to developing practical criteria for systematic use in antifungal prophylaxis trials.

Paphitou NI, Ostrosky-Zeichner L, Rex JH.

Med Mycol. 2005 May;43(3):235-43.PMID: 16010850 [PubMed - indexed for MEDLINE]Related articles

New agents for the treatment of systemic fungal infections--current status.

Arikan S, Rex JH.

Expert Opin Emerg Drugs. 2002 May;7(1):3-32.PMID: 15989533 [PubMed]Related articles

Immunomodulation with interferon-gamma and colony-stimulating factors for refractory fungal infections in patients with leukemia.

Dignani MC, Rex JH, Chan KW, Dow G, deMagalhaes-Silverman M, Maddox A, Walsh T, Anaissie E.

Cancer. 2005 Jul 1;104(1):199-204.PMID: 15929126 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of PCR- and HinfI restriction endonuclease-based methods for typing of Candida krusei isolates.

Sancak B, Rex JH, Chen E, Marr K.

J Clin Microbiol. 2004 Dec;42(12):5889-91.PMID: 15583333 [PubMed - indexed for MEDLINE]Related articlesFree article

The design of clinical trials that evaluate antifungal prophylaxis and combination therapy: introduction and overview.

Rex JH, Wingard JR, Wenzel R, Herbrecht R, Sobel J, Edwards JE Jr.

Clin Infect Dis. 2004 Oct 15;39 Suppl 4:S165-9.PMID: 15546112 [PubMed - indexed for MEDLINE]Related articles

Staying ahead of the fourth horseman.

Rex JH.

Nat Rev Microbiol. 2004 Sep;2(9):684. No abstract available. PMID: 15378807 [PubMed - indexed for MEDLINE]Related articles

Beta-D-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndrome.

Odabasi Z, Mattiuzzi G, Estey E, Kantarjian H, Saeki F, Ridge RJ, Ketchum PA, Finkelman MA, Rex JH, Ostrosky-Zeichner L.

Clin Infect Dis. 2004 Jul 15;39(2):199-205. Epub 2004 Jun 28.PMID: 15307029 [PubMed - indexed for MEDLINE]Related articles

Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species.

Odds FC, Motyl M, Andrade R, Bille J, Cantón E, Cuenca-Estrella M, Davidson A, Durussel C, Ellis D, Foraker E, Fothergill AW, Ghannoum MA, Giacobbe RA, Gobernado M, Handke R, Laverdière M, Lee-Yang W, Merz WG, Ostrosky-Zeichner L, Pemán J, Perea S, Perfect JR, Pfaller MA, Proia L, Rex JH, Rinaldi MG, Rodriguez-Tudela JL, Schell WA, Shields C, Sutton DA, Verweij PE, Warnock DW.

J Clin Microbiol. 2004 Aug;42(8):3475-82.PMID: 15297486 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacokinetics of intravenous itraconazole in stable hemodialysis patients.

Mohr JF, Finkel KW, Rex JH, Rodriguez JR, Leitz GJ, Ostrosky-Zeichner L.

Antimicrob Agents Chemother. 2004 Aug;48(8):3151-3.PMID: 15273137 [PubMed - indexed for MEDLINE]Related articlesFree article

Collaborative study of antibiotic medium 3 and flow cytometry for identification of amphotericin B-resistant Candida isolates.

Chaturvedi V, Ramani R, Rex JH.

J Clin Microbiol. 2004 May;42(5):2252-4.PMID: 15131204 [PubMed - indexed for MEDLINE]Related articlesFree article

Determination of fungicidal activities against yeasts and molds: lessons learned from bactericidal testing and the need for standardization.

Pfaller MA, Sheehan DJ, Rex JH.

Clin Microbiol Rev. 2004 Apr;17(2):268-80. Review.PMID: 15084501 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination antifungal therapy.

Johnson MD, MacDougall C, Ostrosky-Zeichner L, Perfect JR, Rex JH.

Antimicrob Agents Chemother. 2004 Mar;48(3):693-715. Review. No abstract available. PMID: 14982754 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacokinetic/pharmacodynamic modeling can help guide targeted antimicrobial therapy for nosocomial gram-negative infections in critically ill patients.

Mohr JF, Wanger A, Rex JH.

Diagn Microbiol Infect Dis. 2004 Feb;48(2):125-30.PMID: 14972382 [PubMed - indexed for MEDLINE]Related articles

Guidelines for treatment of candidiasis.

Pappas PG, Rex JH, Sobel JD, Filler SG, Dismukes WE, Walsh TJ, Edwards JE; Infectious Diseases Society of America.

Clin Infect Dis. 2004 Jan 15;38(2):161-89. Epub 2003 Dec 19. No abstract available. PMID: 14699449 [PubMed - indexed for MEDLINE]Related articles

Voriconazole salvage treatment of invasive candidiasis.

Ostrosky-Zeichner L, Oude Lashof AM, Kullberg BJ, Rex JH.

Eur J Clin Microbiol Infect Dis. 2003 Nov;22(11):651-5. Epub 2003 Oct 17.PMID: 14564539 [PubMed - indexed for MEDLINE]Related articles

Antifungal susceptibility survey of 2,000 bloodstream Candida isolates in the United States.

Ostrosky-Zeichner L, Rex JH, Pappas PG, Hamill RJ, Larsen RA, Horowitz HW, Powderly WG, Hyslop N, Kauffman CA, Cleary J, Mangino JE, Lee J.

Antimicrob Agents Chemother. 2003 Oct;47(10):3149-54.PMID: 14506023 [PubMed - indexed for MEDLINE]Related articlesFree article

A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients.

Pappas PG, Rex JH, Lee J, Hamill RJ, Larsen RA, Powderly W, Kauffman CA, Hyslop N, Mangino JE, Chapman S, Horowitz HW, Edwards JE, Dismukes WE; NIAID Mycoses Study Group.

Clin Infect Dis. 2003 Sep 1;37(5):634-43. Epub 2003 Aug 14.PMID: 12942393 [PubMed - indexed for MEDLINE]Related articles

Disk diffusion-based methods for determining Candida parapsilosis susceptibility to anidulafungin.

Odabasi Z, Paetznick V, Goldstein BP, Rex JH, Ostrosky-Zeichner L.

Antimicrob Agents Chemother. 2003 Sep;47(9):3018-20.PMID: 12937018 [PubMed - indexed for MEDLINE]Related articlesFree article

Amphotericin B: time for a new "gold standard".

Ostrosky-Zeichner L, Marr KA, Rex JH, Cohen SH.

Clin Infect Dis. 2003 Aug 1;37(3):415-25. Epub 2003 Jul 22.PMID: 12884167 [PubMed - indexed for MEDLINE]Related articles

Multicenter evaluation of the reproducibility of the proposed antifungal susceptibility testing method for fermentative yeasts of the Antifungal Susceptibility Testing Subcommittee of the European Committee on Antimicrobial Susceptibility Testing (AFST-EUCAST).

Cuenca-Estrella M, Moore CB, Barchiesi F, Bille J, Chryssanthou E, Denning DW, Donnelly JP, Dromer F, Dupont B, Rex JH, Richardson MD, Sancak B, Verweij PE, Rodríguez-Tudela JL; AFST Subcommittee of the European Committee on Antimicrobial Susceptibility Testing.

Clin Microbiol Infect. 2003 Jun;9(6):467-74.PMID: 12848721 [PubMed - indexed for MEDLINE]Related articles

Retinal lesions as clues to disseminated bacterial and candidal infections: frequency, natural history, and etiology.

Rodríguez-Adrián LJ, King RT, Tamayo-Derat LG, Miller JW, Garcia CA, Rex JH.

Medicine (Baltimore). 2003 May;82(3):187-202. Review.PMID: 12792305 [PubMed - indexed for MEDLINE]Related articles

A randomized and blinded multicenter trial of high-dose fluconazole plus placebo versus fluconazole plus amphotericin B as therapy for candidemia and its consequences in nonneutropenic subjects.

Rex JH, Pappas PG, Karchmer AW, Sobel J, Edwards JE, Hadley S, Brass C, Vazquez JA, Chapman SW, Horowitz HW, Zervos M, McKinsey D, Lee J, Babinchak T, Bradsher RW, Cleary JD, Cohen DM, Danziger L, Goldman M, Goodman J, Hilton E, Hyslop NE, Kett DH, Lutz J, Rubin RH, Scheld WM, Schuster M, Simmons B, Stein DK, Washburn RG, Mautner L, Chu TC, Panzer H, Rosenstein RB, Booth J; National Institute of Allergy and Infectious Diseases Mycoses Study Group.

Clin Infect Dis. 2003 May 15;36(10):1221-8. Epub 2003 May 8.PMID: 12746765 [PubMed - indexed for MEDLINE]Related articles

Correlation between E-test, disk diffusion, and microdilution methods for antifungal susceptibility testing of fluconazole and voriconazole.

Matar MJ, Ostrosky-Zeichner L, Paetznick VL, Rodriguez JR, Chen E, Rex JH.

Antimicrob Agents Chemother. 2003 May;47(5):1647-51.PMID: 12709335 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of a method for identification of Candida dubliniensis bloodstream isolates.

Sancak B, Rex JH, Paetznick V, Chen E, Rodriguez J.

J Clin Microbiol. 2003 Jan;41(1):489-91.PMID: 12517903 [PubMed - indexed for MEDLINE]Related articlesFree article

Deeply invasive candidiasis.

Ostrosky-Zeichner L, Rex JH, Bennett J, Kullberg BJ.

Infect Dis Clin North Am. 2002 Dec;16(4):821-35. Review.PMID: 12512183 [PubMed - indexed for MEDLINE]Related articles

Pathogenic molds (including Aspergillus species) in hospital water distribution systems: a 3-year prospective study and clinical implications for patients with hematologic malignancies.

Anaissie EJ, Stratton SL, Dignani MC, Lee CK, Summerbell RC, Rex JH, Monson TP, Walsh TJ.

Blood. 2003 Apr 1;101(7):2542-6. Epub 2002 Dec 5.PMID: 12468437 [PubMed - indexed for MEDLINE]Related articlesFree article

Cleaning patient shower facilities: a novel approach to reducing patient exposure to aerosolized Aspergillus species and other opportunistic molds.

Anaissie EJ, Stratton SL, Dignani MC, Lee CK, Mahfouz TH, Rex JH, Summerbell RC, Walsh TJ.

Clin Infect Dis. 2002 Oct 15;35(8):E86-8. Epub 2002 Sep 18.PMID: 12355397 [PubMed - indexed for MEDLINE]Related articles

Has antifungal susceptibility testing come of age?

Rex JH, Pfaller MA.

Clin Infect Dis. 2002 Oct 15;35(8):982-9. Epub 2002 Sep 24.PMID: 12355386 [PubMed - indexed for MEDLINE]Related articles

In vitro activities of investigational triazoles against Fusarium species: effects of inoculum size and incubation time on broth microdilution susceptibility test results.

Paphitou NI, Ostrosky-Zeichner L, Paetznick VL, Rodriguez JR, Chen E, Rex JH.

Antimicrob Agents Chemother. 2002 Oct;46(10):3298-300.PMID: 12234865 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of the echinocandin caspofungin on expression of Candida albicans secretory aspartyl proteinases and phospholipase in vitro.

Ripeau JS, Aumont F, Belhumeur P, Ostrosky-Zeichner L, Rex JH, de Repentigny L.

Antimicrob Agents Chemother. 2002 Sep;46(9):3096-100.PMID: 12183282 [PubMed - indexed for MEDLINE]Related articlesFree article