PubMed

Can increased understanding of the role of lung development and aging drive new advances in chronic obstructive pulmonary disease?

Maciewicz RA, Warburton D, Rennard SI.

Proc Am Thorac Soc. 2009 Dec 1;6(7):614-7.PMID: 19934358 [PubMed - in process]Free article

Introduction: Ninth Lund COPD Symposium.

Rennard SI, Warburton D.

Proc Am Thorac Soc. 2009 Dec 1;6(7):557. No abstract available. PMID: 19934348 [PubMed - in process]Free article

Statins inhibit MMP release from human lung fibroblasts.

Kamio K, Liu XD, Sugiura H, Togo S, Kawasaki S, Wang X, Ahn Y, Hogaboam C, Rennard SI.

Eur Respir J. 2009 Sep 24. [Epub ahead of print]PMID: 19797126 [PubMed - as supplied by publisher]Related articles

Development of predictive models for airflow obstruction in alpha-1-antitrypsin deficiency.

Castaldi PJ, DeMeo DL, Kent DM, Campbell EJ, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino G, Sandhaus RA, Griffith JL, Silverman EK.

Am J Epidemiol. 2009 Oct 15;170(8):1005-13. Epub 2009 Sep 2.PMID: 19726494 [PubMed - indexed for MEDLINE]Related articles

Budesonide and the risk of pneumonia: a meta-analysis of individual patient data.

Sin DD, Tashkin D, Zhang X, Radner F, Sjöbring U, Thorén A, Calverley PM, Rennard SI.

Lancet. 2009 Aug 29;374(9691):712-9.PMID: 19716963 [PubMed - indexed for MEDLINE]Related articles

3-Nitrotyrosine inhibits fibroblast-mediated collagen gel contraction and chemotaxis.

Sugiura H, Liu X, Ichikawa T, Ichinose M, Rennard SI.

Eur Respir J. 2009 Dec;34(6):1452-60. Epub 2009 May 14.PMID: 19443526 [PubMed - in process]Related articles

N-acetyl-L-cysteine inhibits TGF-beta1-induced profibrotic responses in fibroblasts.

Sugiura H, Ichikawa T, Liu X, Kobayashi T, Wang XQ, Kawasaki S, Togo S, Kamio K, Mao L, Ann Y, Ichinose M, Rennard SI.

Pulm Pharmacol Ther. 2009 Dec;22(6):487-91. Epub 2009 Apr 22.PMID: 19393328 [PubMed - in process]Related articles

Efficacy and tolerability of budesonide/formoterol in one hydrofluoroalkane pressurized metered-dose inhaler in patients with chronic obstructive pulmonary disease: results from a 1-year randomized controlled clinical trial.

Rennard SI, Tashkin DP, McElhattan J, Goldman M, Ramachandran S, Martin UJ, Silkoff PE.

Drugs. 2009;69(5):549-65. doi: 10.2165/00003495-200969050-00004.PMID: 19368417 [PubMed - indexed for MEDLINE]Related articles

Comorbidities, patient knowledge, and disease management in a national sample of patients with COPD.

Barr RG, Celli BR, Mannino DM, Petty T, Rennard SI, Sciurba FC, Stoller JK, Thomashow BM, Turino GM.

Am J Med. 2009 Apr;122(4):348-55.PMID: 19332230 [PubMed - indexed for MEDLINE]Related articles

PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts.

Togo S, Liu X, Wang X, Sugiura H, Kamio K, Kawasaki S, Kobayashi T, Ertl RF, Ahn Y, Holz O, Magnussen H, Fredriksson K, Skold CM, Rennard SI.

Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L959-69. Epub 2009 Mar 20.PMID: 19304913 [PubMed - indexed for MEDLINE]Related articles

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, Need AC, Feng S, Hersh CP, Bakke P, Gulsvik A, Ruppert A, Lødrup Carlsen KC, Roses A, Anderson W, Rennard SI, Lomas DA, Silverman EK, Goldstein DB; ICGN Investigators.

PLoS Genet. 2009 Mar;5(3):e1000421. Epub 2009 Mar 20.PMID: 19300482 [PubMed - indexed for MEDLINE]Related articlesFree article

C-reactive protein modulates human lung fibroblast migration.

Kikuchi K, Kohyama T, Yamauchi Y, Kato J, Takami K, Okazaki H, Desaki M, Nagase T, Rennard SI, Takizawa H.

Exp Lung Res. 2009 Feb;35(1):48-58.PMID: 19191104 [PubMed - indexed for MEDLINE]Related articles

MicroRNA-146a modulates human bronchial epithelial cell survival in response to the cytokine-induced apoptosis.

Liu X, Nelson A, Wang X, Kanaji N, Kim M, Sato T, Nakanishi M, Li Y, Sun J, Michalski J, Patil A, Basma H, Rennard SI.

Biochem Biophys Res Commun. 2009 Feb 27;380(1):177-82. Epub 2009 Jan 22.PMID: 19167348 [PubMed - indexed for MEDLINE]Related articles

Natural histories of chronic obstructive pulmonary disease.

Rennard SI, Vestbo J.

Proc Am Thorac Soc. 2008 Dec 15;5(9):878-83.PMID: 19056710 [PubMed - indexed for MEDLINE]Related articlesFree article

Lessons from multidisciplinary cross-fertilization: chronic obstructive pulmonary disease, lung cancer, and heart disease.

Rennard SI.

Proc Am Thorac Soc. 2008 Dec 1;5(8):865-8.PMID: 19017742 [PubMed - indexed for MEDLINE]Related articlesFree article

Foreword: "The Big Three".

Rennard SI, Higenbottam T, Leff AR.

Proc Am Thorac Soc. 2008 Dec 1;5(8):795. No abstract available. PMID: 19017731 [PubMed - indexed for MEDLINE]Related articlesFree article

Heritability of lung function in severe alpha-1 antitrypsin deficiency.

DeMeo DL, Campbell EJ, Brantly ML, Barker AF, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino G, Sandhaus RA, Silverman EK.

Hum Hered. 2009;67(1):38-45. Epub 2008 Oct 17.PMID: 18931508 [PubMed - indexed for MEDLINE]Related articles

The many "small COPDs": COPD should be an orphan disease.

Rennard SI, Vestbo J.

Chest. 2008 Sep;134(3):623-7.PMID: 18779197 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: results of a 6-month randomized clinical trial.

Tashkin DP, Rennard SI, Martin P, Ramachandran S, Martin UJ, Silkoff PE, Goldman M.

Drugs. 2008;68(14):1975-2000.PMID: 18778120 [PubMed - indexed for MEDLINE]Related articles

Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease.

Patel BD, Coxson HO, Pillai SG, Agustí AG, Calverley PM, Donner CF, Make BJ, Müller NL, Rennard SI, Vestbo J, Wouters EF, Hiorns MP, Nakano Y, Camp PG, Nasute Fauerbach PV, Screaton NJ, Campbell EJ, Anderson WH, Paré PD, Levy RD, Lake SL, Silverman EK, Lomas DA; International COPD Genetics Network.

Am J Respir Crit Care Med. 2008 Sep 1;178(5):500-5. Epub 2008 Jun 19.PMID: 18565956 [PubMed - indexed for MEDLINE]Related articlesFree article

Lung fibroblast repair functions in patients with chronic obstructive pulmonary disease are altered by multiple mechanisms.

Togo S, Holz O, Liu X, Sugiura H, Kamio K, Wang X, Kawasaki S, Ahn Y, Fredriksson K, Skold CM, Mueller KC, Branscheid D, Welker L, Watz H, Magnussen H, Rennard SI.

Am J Respir Crit Care Med. 2008 Aug 1;178(3):248-60. Epub 2008 May 8.PMID: 18467512 [PubMed - indexed for MEDLINE]Related articlesFree article

Prostacyclin analogs stimulate VEGF production from human lung fibroblasts in culture.

Kamio K, Sato T, Liu X, Sugiura H, Togo S, Kobayashi T, Kawasaki S, Wang X, Mao L, Ahn Y, Holz O, Magnussen H, Rennard SI.

Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1226-32. Epub 2008 Apr 18.PMID: 18424619 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingosine 1-phosphate potentiates human lung fibroblast chemotaxis through the S1P2 receptor.

Hashimoto M, Wang X, Mao L, Kobayashi T, Kawasaki S, Mori N, Toews ML, Kim HJ, Cerutis DR, Liu X, Rennard SI.

Am J Respir Cell Mol Biol. 2008 Sep;39(3):356-63. Epub 2008 Mar 26.PMID: 18367729 [PubMed - indexed for MEDLINE]Related articlesFree article

Update on smoking cessation interventions for the primary care physician. Introduction.

Rennard SI.

Am J Med. 2008 Apr;121(4 Suppl 1):S1-2. No abstract available. PMID: 18342161 [PubMed - indexed for MEDLINE]Related articles

PKCdelta mediates thrombin-augmented fibroblast-mediated collagen gel contraction.

Fang Q, Mao L, Kobayashi T, Wang X, Wyatt TA, Kim H, Liu X, Rennard SI.

Biochem Biophys Res Commun. 2008 May 16;369(4):1199-203. Epub 2008 Mar 13.PMID: 18342628 [PubMed - indexed for MEDLINE]Related articlesFree article

Outcomes for COPD pharmacological trials: from lung function to biomarkers.

Cazzola M, MacNee W, Martinez FJ, Rabe KF, Franciosi LG, Barnes PJ, Brusasco V, Burge PS, Calverley PM, Celli BR, Jones PW, Mahler DA, Make B, Miravitlles M, Page CP, Palange P, Parr D, Pistolesi M, Rennard SI, Rutten-van Mölken MP, Stockley R, Sullivan SD, Wedzicha JA, Wouters EF; American Thoracic Society; European Respiratory Society Task Force on outcomes of COPD.

Eur Respir J. 2008 Feb;31(2):416-69. Review.PMID: 18238951 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of exercise on hematological parameters, circulating side population cells, and cytokines.

Wardyn GG, Rennard SI, Brusnahan SK, McGuire TR, Carlson ML, Smith LM, McGranaghan S, Sharp JG.

Exp Hematol. 2008 Feb;36(2):216-23.PMID: 18206729 [PubMed - indexed for MEDLINE]Related articles

Knowledge and beliefs about genetics and smoking among visitors and staff at a health care facility.

Houfek JF, Atwood JR, Wolfe RM, Agrawal S, Reiser GM, Schaefer GB, Rennard SI.

Public Health Nurs. 2008 Jan-Feb;25(1):77-87.PMID: 18173588 [PubMed - indexed for MEDLINE]Related articles

Enhancing COPD management in primary care settings.

Foster JA, Yawn BP, Maziar A, Jenkins T, Rennard SI, Casebeer L.

MedGenMed. 2007 Jul 31;9(3):24.PMID: 18092030 [PubMed - indexed for MEDLINE]Related articlesFree article

Exacerbation-free COPD: a goal too far?

Rennard SI, Higenbottam T.

Proc Am Thorac Soc. 2007 Dec;4(8):583-5.PMID: 18073386 [PubMed - indexed for MEDLINE]Related articlesFree article

Eicosanoids mediate insect hemocyte migration.

Merchant D, Ertl RL, Rennard SI, Stanley DW, Miller JS.

J Insect Physiol. 2008 Jan;54(1):215-21. Epub 2007 Sep 19.PMID: 17996890 [PubMed - indexed for MEDLINE]Related articles

Inhalation of tobacco smoke induces increased proliferation of urinary bladder epithelium and endothelium in female C57BL/6 mice.

Ohnishi T, Arnold LL, He J, Clark NM, Kawasaki S, Rennard SI, Boyer CW, Cohen SM.

Toxicology. 2007 Nov 20;241(1-2):58-65. Epub 2007 Aug 19.PMID: 17897767 [PubMed - indexed for MEDLINE]Related articles

What have we learned from large drug treatment trials in COPD?

Calverley PM, Rennard SI.

Lancet. 2007 Sep 1;370(9589):774-85. Review.PMID: 17765527 [PubMed - indexed for MEDLINE]Related articles

IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency.

Demeo DL, Campbell EJ, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Sandhaus RA, Stocks JM, Stoller JK, Strange C, Turino G, Silverman EK.

Am J Respir Cell Mol Biol. 2008 Jan;38(1):114-20. Epub 2007 Aug 9.PMID: 17690329 [PubMed - indexed for MEDLINE]Related articlesFree article

Cultured lung fibroblasts from ovalbumin-challenged "asthmatic" mice differ functionally from normal.

Sugiura H, Liu X, Duan F, Kawasaki S, Togo S, Kamio K, Wang XQ, Mao L, Ahn Y, Ertl RF, Bargar TW, Berro A, Casale TB, Rennard SI.

Am J Respir Cell Mol Biol. 2007 Oct;37(4):424-30. Epub 2007 Jun 15.PMID: 17575074 [PubMed - indexed for MEDLINE]Related articlesFree article

The CC chemokine ligand 2 (CCL2) mediates fibroblast survival through IL-6.

Liu X, Das AM, Seideman J, Griswold D, Afuh CN, Kobayashi T, Abe S, Fang Q, Hashimoto M, Kim H, Wang X, Shen L, Kawasaki S, Rennard SI.

Am J Respir Cell Mol Biol. 2007 Jul;37(1):121-8. Epub 2007 Mar 22.PMID: 17379849 [PubMed - indexed for MEDLINE]Related articlesFree article

Comment: Oral varenicline for smoking cessation.

Gonzales D, Rennard SI, Jorenby DE, Reeves KR.

Ann Pharmacother. 2007 Apr;41(4):720-1. Epub 2007 Mar 20. No abstract available. PMID: 17374627 [PubMed - indexed for MEDLINE]Related articles

Prostacyclin analogs inhibit fibroblast contraction of collagen gels through the cAMP-PKA pathway.

Kamio K, Liu X, Sugiura H, Togo S, Kobayashi T, Kawasaki S, Wang X, Mao L, Ahn Y, Hogaboam C, Toews ML, Rennard SI.

Am J Respir Cell Mol Biol. 2007 Jul;37(1):113-20. Epub 2007 Mar 15.PMID: 17363776 [PubMed - indexed for MEDLINE]Related articlesFree article

The safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary disease.

Rennard SI, Fogarty C, Kelsen S, Long W, Ramsdell J, Allison J, Mahler D, Saadeh C, Siler T, Snell P, Korenblat P, Smith W, Kaye M, Mandel M, Andrews C, Prabhu R, Donohue JF, Watt R, Lo KH, Schlenker-Herceg R, Barnathan ES, Murray J; COPD Investigators.

Am J Respir Crit Care Med. 2007 May 1;175(9):926-34. Epub 2007 Feb 8.PMID: 17290043 [PubMed - indexed for MEDLINE]Related articlesFree article

Minimal clinically important difference, clinical perspective: an opinion.

Rennard SI.

COPD. 2005 Mar;2(1):51-5. Review.PMID: 17136962 [PubMed - indexed for MEDLINE]Related articles

Cigarette smoke inhibits alveolar repair: a mechanism for the development of emphysema.

Rennard SI, Togo S, Holz O.

Proc Am Thorac Soc. 2006 Nov;3(8):703-8. Review.PMID: 17065377 [PubMed - indexed for MEDLINE]Related articlesFree article

Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation.

Sugiura H, Liu X, Togo S, Kobayashi T, Shen L, Kawasaki S, Kamio K, Wang XQ, Mao LJ, Rennard SI.

J Cell Physiol. 2007 Jan;210(1):99-110.PMID: 16998801 [PubMed - indexed for MEDLINE]Related articles

Cigarette smoke stimulates MMP-1 production by human lung fibroblasts through the ERK1/2 pathway.

Kim H, Liu X, Kohyama T, Kobayashi T, Conner H, Abe S, Fang Q, Wen FQ, Rennard SI.

COPD. 2004 Apr;1(1):13-23.PMID: 16997735 [PubMed - indexed for MEDLINE]Related articles

Biomarkers to assess the utility of potential reduced exposure tobacco products.

Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS.

Nicotine Tob Res. 2006 Aug;8(4):600-22. Review.PMID: 16920658 [PubMed - indexed for MEDLINE]Related articles

Efficacy of the nicotine inhaler in smoking reduction: A double-blind, randomized trial.

Rennard SI, Glover ED, Leischow S, Daughton DM, Glover PN, Muramoto M, Franzon M, Danielsson T, Landfeldt B, Westin A.

Nicotine Tob Res. 2006 Aug;8(4):555-64.PMID: 16920653 [PubMed - indexed for MEDLINE]Related articles

Examining the exhaled levels of hydrogen peroxide in rheumatoid arthritis: a pilot study.

Mikuls TR, O'Dell JR, Ertl R, Bergman DA, Rennard SI.

Ann Rheum Dis. 2006 Sep;65(9):1252-3. No abstract available. PMID: 16905587 [PubMed - indexed for MEDLINE]Related articlesFree article

Thrombin and TNF-alpha/IL-1beta synergistically induce fibroblast-mediated collagen gel degradation.

Fang Q, Liu X, Al-Mugotir M, Kobayashi T, Abe S, Kohyama T, Rennard SI.

Am J Respir Cell Mol Biol. 2006 Dec;35(6):714-21. Epub 2006 Jul 20.PMID: 16858010 [PubMed - indexed for MEDLINE]Related articlesFree article

Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.

Gonzales D, Rennard SI, Nides M, Oncken C, Azoulay S, Billing CB, Watsky EJ, Gong J, Williams KE, Reeves KR; Varenicline Phase 3 Study Group.

JAMA. 2006 Jul 5;296(1):47-55.PMID: 16820546 [PubMed - indexed for MEDLINE]Related articlesFree article

Biomarkers to assess the utility of potential reduced exposure tobacco products.

Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS.

Nicotine Tob Res. 2006 Apr;8(2):169-91. Review. Corrected and republished in: Nicotine Tob Res. 2006 Aug;8(4):600-22. PMID: 16766411 [PubMed - indexed for MEDLINE]Related articles

Smad3 deficiency alters key structural elements of the extracellular matrix and mechanotransduction of wound closure.

Arany PR, Flanders KC, Kobayashi T, Kuo CK, Stuelten C, Desai KV, Tuan R, Rennard SI, Roberts AB.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9250-5. Epub 2006 Jun 5.PMID: 16754864 [PubMed - indexed for MEDLINE]Related articlesFree article