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Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGF.

Almeida S, Cunha-Oliveira T, Laço M, Oliveira CR, Rego AC.

Neurotox Res. 2009 Sep 25. [Epub ahead of print]PMID: 19779956 [PubMed - as supplied by publisher]Related articles

BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons.

Almeida S, Laço M, Cunha-Oliveira T, Oliveira CR, Rego AC.

Neurobiol Dis. 2009 Sep;35(3):448-56. Epub 2009 Jun 23.PMID: 19555760 [PubMed - in process]Related articles

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease.

Moreira PI, Duarte AI, Santos MS, Rego AC, Oliveira CR.

J Alzheimers Dis. 2009 Apr;16(4):741-61. Review.PMID: 19387110 [PubMed - indexed for MEDLINE]Related articles

BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype.

Silva A, Pereira J, Oliveira CR, Relvas JB, Rego AC.

J Neurosci Res. 2009 Jul;87(9):1986-96.PMID: 19267421 [PubMed - indexed for MEDLINE]Related articles

Biodistribution of samarium-153-EDTMP in rats treated with docetaxel.

Villarim Neto A, Açucena MK, Pereira KR, Rêgo AC, Azevedo IM, Bernardo-Filho M, Medeiros AC.

Acta Cir Bras. 2009 Jan-Feb;24(1):62-6.PMID: 19169545 [PubMed - in process]Related articlesFree article

The R6 lines of transgenic mice: a model for screening new therapies for Huntington's disease.

Gil JM, Rego AC.

Brain Res Rev. 2009 Mar;59(2):410-31. Epub 2008 Dec 16. Review.PMID: 19118572 [PubMed - indexed for MEDLINE]Related articles

Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients.

Almeida S, Sarmento-Ribeiro AB, Januário C, Rego AC, Oliveira CR.

Biochem Biophys Res Commun. 2008 Oct 3;374(4):599-603. Epub 2008 Jul 14.PMID: 18625199 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of neurodegeneration in Huntington's disease.

Gil JM, Rego AC.

Eur J Neurosci. 2008 Jun;27(11):2803-20. Review. Erratum in: Eur J Neurosci. 2008 Nov;28(10):2156. PMID: 18588526 [PubMed - indexed for MEDLINE]Related articles

Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs.

Cunha-Oliveira T, Rego AC, Oliveira CR.

Brain Res Rev. 2008 Jun;58(1):192-208. Epub 2008 Mar 27. Review.PMID: 18440072 [PubMed - indexed for MEDLINE]Related articles

Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3beta signaling pathways and changes in protein expression.

Duarte AI, Santos P, Oliveira CR, Santos MS, Rego AC.

Biochim Biophys Acta. 2008 Jun;1783(6):994-1002. Epub 2008 Feb 29.PMID: 18348871 [PubMed - indexed for MEDLINE]Related articles

Biodistribution of the radiophamarceutical sodium pertechnetate (Na99mTcO4) after massive small bowel resection in rats.

Chacon Dde A, Araújo-Filho I, Villarim-Neto A, Rêgo AC, Azevedo IM, Bernardo-Filho M, Brandão-Neto J, Medeiros AC.

Acta Cir Bras. 2007 Nov-Dec;22(6):430-5.PMID: 18235929 [PubMed - indexed for MEDLINE]Related articlesFree article

Bcl-2 overexpression protects against amyloid-beta and prion toxicity in GT1-7 neural cells.

Ferreiro E, Eufrásio A, Pereira C, Oliveira CR, Rego AC.

J Alzheimers Dis. 2007 Nov;12(3):223-8.PMID: 18057555 [PubMed - indexed for MEDLINE]Related articles

Simvastatin improves the healing of infected skin wounds of rats.

Rego AC, Araújo Filho I, Damasceno BP, Egito ES, Silveira IA, Brandão-Neto J, Medeiros AC.

Acta Cir Bras. 2007 Mar-Apr;22 Suppl 1:57-63.PMID: 17505657 [PubMed - indexed for MEDLINE]Related articlesFree article

Trolox protection of myelin membrane in hydrogen peroxide-treated mature oligodendrocytes.

Perfeito R, Pereira J, Oliveira CR, Bettencourt-Relvas J, Rego AC.

Free Radic Res. 2007 Apr;41(4):444-51. Erratum in: Free Radic Res. 2007 Jun;41(6):738-9. PMID: 17454126 [PubMed - indexed for MEDLINE]Related articles

Toxicity of beta-amyloid in HEK293 cells expressing NR1/NR2A or NR1/NR2B N-methyl-D-aspartate receptor subunits.

Domingues A, Almeida S, da Cruz e Silva EF, Oliveira CR, Rego AC.

Neurochem Int. 2007 May;50(6):872-80. Epub 2007 Mar 7.PMID: 17403555 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice.

Oliveira JM, Jekabsons MB, Chen S, Lin A, Rego AC, Gonçalves J, Ellerby LM, Nicholls DG.

J Neurochem. 2007 Apr;101(1):241-9.PMID: 17394466 [PubMed - indexed for MEDLINE]Related articles

Prevention of bacterial translocation using beta-(1-3)-D-glucan in small bowel ischemia and reperfusion in rats.

Araújo-Filho I, Rêgo AC, Pinheiro LA, Azevedo IM, Medeiros VB, Brandão-Neto J, Medeiros AC.

Acta Cir Bras. 2006;21 Suppl 4:18-22.PMID: 17293960 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of simvastatin in abdominal sepsis in rats.

Souza Neto JL, Araújo Filho I, Rego AC, Dominici VA, Azevedo IM, Egito ES, Brandão-Neto J, Medeiros AC.

Acta Cir Bras. 2006;21 Suppl 4:8-12.PMID: 17293958 [PubMed - indexed for MEDLINE]Related articlesFree article

Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons.

Cunha-Oliveira T, Rego AC, Garrido J, Borges F, Macedo T, Oliveira CR.

J Neurochem. 2007 Apr;101(2):543-54. Epub 2007 Jan 23.PMID: 17250679 [PubMed - indexed for MEDLINE]Related articles

Expression of NR1/NR2B N-methyl-D-aspartate receptors enhances heroin toxicity in HEK293 cells.

Domingues A, Cunha Oliveira T, Laço ML, Macedo TR, Oliveira CR, Rego AC.

Ann N Y Acad Sci. 2006 Aug;1074:458-65.PMID: 17105944 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors.

Oliveira JM, Chen S, Almeida S, Riley R, Gonçalves J, Oliveira CR, Hayden MR, Nicholls DG, Ellerby LM, Rego AC.

J Neurosci. 2006 Oct 25;26(43):11174-86.PMID: 17065457 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine ("ecstasy") and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship.

Milhazes N, Cunha-Oliveira T, Martins P, Garrido J, Oliveira C, Rego AC, Borges F.

Chem Res Toxicol. 2006 Oct;19(10):1294-304.PMID: 17040098 [PubMed - indexed for MEDLINE]Related articles

Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.

Duarte AI, Proença T, Oliveira CR, Santos MS, Rego AC.

Diabetes. 2006 Oct;55(10):2863-70.PMID: 17003354 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine.

Cunha-Oliveira T, Rego AC, Cardoso SM, Borges F, Swerdlow RH, Macedo T, de Oliveira CR.

Brain Res. 2006 May 17;1089(1):44-54. Epub 2006 Apr 25.PMID: 16638611 [PubMed - indexed for MEDLINE]Related articles

Influence of laparoscopy and laparotomy on gasometry, leukocytes and cytokines in a rat abdominal sepsis model.

Araújo Filho I, Honorato Sobrinho AA, Rego AC, Garcia AC, Fernandes DP, Cruz TM, Costa TC, Medeiros AC.

Acta Cir Bras. 2006 Mar-Apr;21(2):74-9. Epub 2006 Mar 21.PMID: 16583058 [PubMed - indexed for MEDLINE]Related articlesFree article

Caspase-dependent and -independent cell death induced by 3-nitropropionic acid in rat cortical neurons.

Almeida S, Brett AC, Góis IN, Oliveira CR, Rego AC.

J Cell Biochem. 2006 May 1;98(1):93-101.PMID: 16365893 [PubMed - indexed for MEDLINE]Related articles

Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide.

Cunha-Oliveira T, Rego AC, Morgadinho MT, Macedo T, Oliveira CR.

Toxicology. 2006 Jan 5;217(1):54-62. Epub 2005 Oct 19.PMID: 16242230 [PubMed - indexed for MEDLINE]Related articles

Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity.

Cardoso SM, Rego AC, Pereira C, Oliveira CR.

Neurotox Res. 2005;7(4):273-81.PMID: 16179264 [PubMed - indexed for MEDLINE]Related articles

Effect of chronic exposure to aluminium on isoform expression and activity of rat (Na+/K+)ATPase.

Silva VS, Duarte AI, Rego AC, Oliveira CR, Gonçalves PP.

Toxicol Sci. 2005 Dec;88(2):485-94. Epub 2005 Sep 14.PMID: 16162844 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.

Duarte AI, Santos MS, Oliveira CR, Rego AC.

Free Radic Biol Med. 2005 Oct 1;39(7):876-89.PMID: 16140208 [PubMed - indexed for MEDLINE]Related articles

Molecular targets and therapeutic strategies in Huntington's disease.

Rego AC, de Almeida LP.

Curr Drug Targets CNS Neurol Disord. 2005 Aug;4(4):361-81. Review.PMID: 16101555 [PubMed - indexed for MEDLINE]Related articles

Carvedilol protects ischemic cardiac mitochondria by preventing oxidative stress.

Carreira R, Duarte A, Monteiro P, Santos MS, Rego AC, Oliveira CR, Gonçalves LM, Providência LA.

Rev Port Cardiol. 2004 Nov;23(11):1447-55. English, Portuguese. PMID: 15693697 [PubMed - indexed for MEDLINE]Related articles

FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures.

Almeida S, Domingues A, Rodrigues L, Oliveira CR, Rego AC.

Neurobiol Dis. 2004 Dec;17(3):435-44.PMID: 15571979 [PubMed - indexed for MEDLINE]Related articles

Apoptotic cell death induced by hydrogen peroxide in NT2 parental and mitochondrial DNA depleted cells.

Cardoso SM, Rego AC, Penacho N, Oliveira CR.

Neurochem Int. 2004 Oct;45(5):693-8.PMID: 15234112 [PubMed - indexed for MEDLINE]Related articles

Drugs of abuse induce apoptotic features in PC12 cells.

Oliveira MT, Rego AC, Macedo TR, Oliveira CR.

Ann N Y Acad Sci. 2003 Dec;1010:667-70.PMID: 15033808 [PubMed - indexed for MEDLINE]Related articles

Bcl-2 prevents loss of cell viability and caspase activation induced by 3-nitropropionic acid in GT1-7 cells.

Brito O, Almeida S, Oliveira CR, Rego AC.

Ann N Y Acad Sci. 2003 Dec;1010:148-52.PMID: 15033710 [PubMed - indexed for MEDLINE]Related articles

Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

Gil J, Almeida S, Oliveira CR, Rego AC.

Free Radic Biol Med. 2003 Dec 1;35(11):1500-14.PMID: 14642398 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases.

Rego AC, Oliveira CR.

Neurochem Res. 2003 Oct;28(10):1563-74. Review.PMID: 14570402 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.

Rego AC, Monteiro NM, Silva AP, Gil J, Malva JO, Oliveira CR.

J Neurochem. 2003 Aug;86(4):792-804.PMID: 12887678 [PubMed - indexed for MEDLINE]Related articles

Effect of amyloid beta-peptide on permeability transition pore: a comparative study.

Moreira PI, Santos MS, Moreno A, Rego AC, Oliveira C.

J Neurosci Res. 2002 Jul 15;69(2):257-67.PMID: 12111807 [PubMed - indexed for MEDLINE]Related articles

Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells.

Oliveira MT, Rego AC, Morgadinho MT, Macedo TR, Oliveira CR.

Ann N Y Acad Sci. 2002 Jun;965:487-96.PMID: 12105124 [PubMed - indexed for MEDLINE]Related articles

The mechanism of mitochondrial membrane potential retention following release of cytochrome c in apoptotic GT1-7 neural cells.

Rego AC, Vesce S, Nicholls DG.

Cell Death Differ. 2001 Oct;8(10):995-1003.PMID: 11598797 [PubMed - indexed for MEDLINE]Related articlesFree article

Antioxidant effect of flavonoids after ascorbate/Fe(2+)-induced oxidative stress in cultured retinal cells.

Areias FM, Rego AC, Oliveira CR, Seabra RM.

Biochem Pharmacol. 2001 Jul 1;62(1):111-8.PMID: 11377402 [PubMed - indexed for MEDLINE]Related articles

Glutamate regulates the viability of retinal cells in culture.

Rego AC, Santos MS, Areias F, Proença T, Oliveira CR.

Vision Res. 2001 Mar;41(7):841-51.PMID: 11248270 [PubMed - indexed for MEDLINE]Related articles

Mitochondria control ampa/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells.

Rego AC, Ward MW, Nicholls DG.

J Neurosci. 2001 Mar 15;21(6):1893-901.PMID: 11245674 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmental profile of excitatory GABA(A) responses in cultured rat cerebellar granule cells.

Rego AC, Lambert JJ, Nicholls DG.

Neuroreport. 2001 Mar 5;12(3):477-82.PMID: 11234749 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells.

Ward MW, Rego AC, Frenguelli BG, Nicholls DG.

J Neurosci. 2000 Oct 1;20(19):7208-19.PMID: 11007877 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenosine A2A receptors regulate the extracellular accumulation of excitatory amino acids upon metabolic dysfunction in chick cultured retinal cells.

Rego AC, Agostinho P, Melo J, Cunha RA, Oliveira CR.

Exp Eye Res. 2000 May;70(5):577-87.PMID: 10870516 [PubMed - indexed for MEDLINE]Related articles

Glutamate-mediated inhibition of oxidative phosphorylation in cultured retinal cells.

Rego AC, Santos MS, Oliveira CR.

Neurochem Int. 2000 Feb;36(2):159-66.PMID: 10676880 [PubMed - indexed for MEDLINE]Related articles

Adenosine modulation of D-[3H]aspartate release in cultured retina cells exposed to oxidative stress.

Agostinho P, Caseiro P, Rego AC, Duarte EP, Cunha RA, Oliveira CR.

Neurochem Int. 2000 Mar;36(3):255-65.PMID: 10676861 [PubMed - indexed for MEDLINE]Related articles