PubMed

Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions.

Advani A, Kelly DJ, Advani SL, Cox AJ, Thai K, Zhang Y, White KE, Gow RM, Marshall SM, Steer BM, Marsden PA, Rakoczy PE, Gilbert RE.

Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14448-53. Epub 2007 Aug 28.PMID: 17726104 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel cationic lipophilic peptides for oligodeoxynucleotide delivery.

Chan E, Amon M, Marano RJ, Wimmer N, Kearns PS, Manolios N, Rakoczy PE, Toth I.

Bioorg Med Chem. 2007 Jun 15;15(12):4091-7. Epub 2007 Mar 30.PMID: 17420133 [PubMed - indexed for MEDLINE]Related articles

Using stem cells to repair the degenerate retina. Stem cells in the context of retinal degenerations.

Hall CM, Kicic A, Lai CM, Rakoczy PE.

Adv Exp Med Biol. 2006;572:381-8. Review. No abstract available. PMID: 17249600 [PubMed - indexed for MEDLINE]Related articles

Controlling vascular endothelial growth factor: therapies for ocular diseases associated with neovascularization.

Marano RJ, Rakoczy PE.

Adv Exp Med Biol. 2006;572:303-7. Review. No abstract available. PMID: 17249588 [PubMed - indexed for MEDLINE]Related articles

Potential use of cellular promoter(s) to target RPE in AAV-mediated delivery. Cellular promoters and RPE-targeting.

Sutanto EN, Zhang D, Lai YK, Shen WY, Rakoczy PE.

Adv Exp Med Biol. 2006;572:267-73. No abstract available. PMID: 17249583 [PubMed - indexed for MEDLINE]Related articles

Pathological heterogeneity of vasoproliferative retinopathy in transgenic mice overexpressing vascular endothelial growth factor in photoreceptors.

Shen WY, Lai YK, Lai CM, Binz N, Beazley LD, Dunlop SA, Rakoczy PE.

Adv Exp Med Biol. 2006;572:187-93. No abstract available. PMID: 17249574 [PubMed - indexed for MEDLINE]Related articles

Regulation of tight junction proteins in cultured retinal pigment epithelial cells and in VEGF overexpressing transgenic mouse retinas.

Ghassemifar R, Lai CM, Rakoczy PE.

Adv Exp Med Biol. 2006;572:179-85. No abstract available. PMID: 17249573 [PubMed - indexed for MEDLINE]Related articles

Characterisation of a model for retinal neovascularisation. VEGF model characterisation.

van Eeden PE, Tee L, Shen WY, Lukehurst S, Lai CM, Rakoczy PE, Beazley LD, Dunlop SA.

Adv Exp Med Biol. 2006;572:163-8. No abstract available. PMID: 17249570 [PubMed - indexed for MEDLINE]Related articles

An improved method using densitometry for evaluating severity of laser photocoagulation induced CNV.

Marano RJ, Rakoczy PE.

Biotech Histochem. 2006 Mar-Jun;81(2-3):59-62.PMID: 16908429 [PubMed - indexed for MEDLINE]Related articles

Long-term global retinal microvascular changes in a transgenic vascular endothelial growth factor mouse model.

Shen WY, Lai CM, Graham CE, Binz N, Lai YK, Eade J, Guidolin D, Ribatti D, Dunlop SA, Rakoczy PE.

Diabetologia. 2006 Jul;49(7):1690-701. Epub 2006 May 10.PMID: 16752188 [PubMed - indexed for MEDLINE]Related articles

Contrasting actions of prolonged mitogen-activated protein kinase activation on cell survival.

Badrian B, Casey TM, Lai MC, Rakoczy PE, Arthur PG, Bogoyevitch MA.

Biochem Biophys Res Commun. 2006 Jun 30;345(2):843-50. Epub 2006 May 5.PMID: 16701555 [PubMed - indexed for MEDLINE]Related articles

Long-term effect of therapeutic laser photocoagulation on gene expression in the eye.

Binz N, Graham CE, Simpson K, Lai YK, Shen WY, Lai CM, Speed TP, Rakoczy PE.

FASEB J. 2006 Feb;20(2):383-5. Epub 2005 Dec 14.PMID: 16354724 [PubMed - indexed for MEDLINE]Related articlesFree article

Eph/ephrin expression in the adult rat visual system following localized retinal lesions: localized and transneuronal up-regulation in the retina and superior colliculus.

Rodger J, Symonds AC, Springbett J, Shen WY, Bartlett CA, Rakoczy PE, Beazley LD, Dunlop SA.

Eur J Neurosci. 2005 Oct;22(8):1840-52.PMID: 16262624 [PubMed - indexed for MEDLINE]Related articles

VEGF differentially regulates transcription and translation of ZO-1alpha+ and ZO-1alpha- and mediates trans-epithelial resistance in cultured endothelial and epithelial cells.

Ghassemifar R, Lai CM, Rakoczy PE.

Cell Tissue Res. 2006 Jan;323(1):117-25. Epub 2005 Sep 15.PMID: 16163490 [PubMed - indexed for MEDLINE]Related articles

Correlation between inactive cathepsin D expression and retinal changes in mcd2/mcd2 transgenic mice.

Zhang D, Brankov M, Makhija MT, Robertson T, Helmerhorst E, Papadimitriou JM, Rakoczy PE.

Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3031-8.PMID: 16123398 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: a long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity.

Marano RJ, Toth I, Wimmer N, Brankov M, Rakoczy PE.

Gene Ther. 2005 Nov;12(21):1544-50.PMID: 16034458 [PubMed - indexed for MEDLINE]Related articles

Are stem cell characteristics altered by disease state?

Kicic A, Hall CM, Shen WY, Rakoczy PE.

Stem Cells Dev. 2005 Feb;14(1):15-28.PMID: 15725741 [PubMed - indexed for MEDLINE]Related articles

Treatments for choroidal and retinal neovascularization: a focus on oligonucleotide therapy and delivery for the regulation of gene function.

Marano RJ, Rakoczy PE.

Clin Experiment Ophthalmol. 2005 Feb;33(1):81-9. Review.PMID: 15670087 [PubMed - indexed for MEDLINE]Related articles

Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide.

Marano RJ, Wimmer N, Kearns PS, Thomas BG, Toth I, Brankov M, Rakoczy PE.

Exp Eye Res. 2004 Oct;79(4):525-35.PMID: 15381036 [PubMed - indexed for MEDLINE]Related articles

Discovery of a novel control element within the 5'-untranslated region of the vascular endothelial growth factor. Regulation of expression using sense oligonucleotides.

Marano RJ, Brankov M, Rakoczy PE.

J Biol Chem. 2004 Sep 3;279(36):37808-14. Epub 2004 Jun 22.PMID: 15213238 [PubMed - indexed for MEDLINE]Related articlesFree article

Virus-mediated secretion gene therapy--a potential treatment for ocular neovascularization.

Lai YK, Sharma S, Lai CM, Brankov M, Constable IJ, Rakoczy PE.

Adv Exp Med Biol. 2003;533:447-53. No abstract available. PMID: 15180297 [PubMed - indexed for MEDLINE]Related articles

Assessment of rAAV-mediated gene therapy in the Rpe65-/- mouse.

Rakoczy PE, Lai CM, Yu MJ, Daniels DM, Brankov M, Rae BC, Stoddart CW, Barnett NL, Martin-Iverson MT, Redmond TM, Narfstrom K, Zhou X, Constable IJ.

Adv Exp Med Biol. 2003;533:431-8. No abstract available. PMID: 15180295 [PubMed - indexed for MEDLINE]Related articles

Functional and structural evaluation after AAV.RPE65 gene transfer in the canine model of Leber's congenital amaurosis.

Narfström K, Bragadóttir R, Redmond TM, Rakoczy PE, van Veen T, Bruun A.

Adv Exp Med Biol. 2003;533:423-30. No abstract available. PMID: 15180294 [PubMed - indexed for MEDLINE]Related articles

Marrow stromal cells (MSC): a species comparison.

Kicic A, Shanley AC, Hall CM, Rakoczy PE.

Adv Exp Med Biol. 2003;533:407-14. No abstract available. PMID: 15180292 [PubMed - indexed for MEDLINE]Related articles

Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65-/- knockout mouse eye results in limited rescue.

Lai CM, Yu MJ, Brankov M, Barnett NL, Zhou X, Redmond TM, Narfstrom K, Rakoczy PE.

Genet Vaccines Ther. 2004 Apr 27;2(1):3.PMID: 15109394 [PubMed - as supplied by publisher]Related articlesFree article

Concurrent enhancement of transcriptional activity and specificity of a retinal pigment epithelial cell-preferential promoter.

Zhang D, Sutanto EN, Rakoczy PE.

Mol Vis. 2004 Mar 26;10:208-14.PMID: 15064682 [PubMed - indexed for MEDLINE]Related articlesFree article

Predilection of the macular region to high incidence of choroidal neovascularization after intense laser photocoagulation in the monkey.

Shen WY, Lee SY, Yeo I, Lai CM, Mathur R, Tan D, Constable IJ, Rakoczy PE.

Arch Ophthalmol. 2004 Mar;122(3):353-60.PMID: 15006849 [PubMed - indexed for MEDLINE]Related articles

Impurity of recombinant adeno-associated virus type 2 affects the transduction characteristics following subretinal injection in the rat.

Shen WY, Lai YK, Lai CM, Rakoczy PE.

Vision Res. 2004 Feb;44(4):339-48.PMID: 14659960 [PubMed - indexed for MEDLINE]Related articles

In vitro comparison studies of truncated rhodopsin promoter fragments from various species in human cell lines.

May LA, Lai CM, Rakoczy PE.

Clin Experiment Ophthalmol. 2003 Oct;31(5):445-50.PMID: 14516435 [PubMed - indexed for MEDLINE]Related articles

Quantitative model demonstrating that recombinant adeno-associated virus and green fluorescent protein are non-toxic to the rat retina.

Daniels DM, Shen WY, Constable IJ, Rakoczy PE.

Clin Experiment Ophthalmol. 2003 Oct;31(5):439-44.PMID: 14516434 [PubMed - indexed for MEDLINE]Related articles

Entrainment of circadian rhythm to a photoperiod reversal shows retinal dystrophy in RPE65(-/-) mice.

Daniels DM, Stoddart CW, Martin-Iverson MT, Lai CM, Redmond TM, Rakoczy PE.

Physiol Behav. 2003 Sep;79(4-5):701-11.PMID: 12954412 [PubMed - indexed for MEDLINE]Related articles

Differentiation of marrow stromal cells into photoreceptors in the rat eye.

Kicic A, Shen WY, Wilson AS, Constable IJ, Robertson T, Rakoczy PE.

J Neurosci. 2003 Aug 27;23(21):7742-9.PMID: 12944502 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene transfer in the RPE65 null mutation dog: relationship between construct volume, visual behavior and electroretinographic (ERG) results.

Ford M, Bragadóttir R, Rakoczy PE, Narfström K.

Doc Ophthalmol. 2003 Jul;107(1):79-86.PMID: 12906125 [PubMed - indexed for MEDLINE]Related articles

Practical considerations of recombinant adeno-associated virus-mediated gene transfer for treatment of retinal degenerations.

Shen WY, Lai CM, Lai YK, Zhang D, Zaknich T, Sutanto EN, Constable IJ, Rakoczy PE.

J Gene Med. 2003 Jul;5(7):576-87.PMID: 12825197 [PubMed - indexed for MEDLINE]Related articles

Functional and structural recovery of the retina after gene therapy in the RPE65 null mutation dog.

Narfström K, Katz ML, Bragadottir R, Seeliger M, Boulanger A, Redmond TM, Caro L, Lai CM, Rakoczy PE.

Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1663-72.PMID: 12657607 [PubMed - indexed for MEDLINE]Related articlesFree article

Argon laser photocoagulation-induced modification of gene expression in the retina.

Wilson AS, Hobbs BG, Shen WY, Speed TP, Schmidt U, Begley CG, Rakoczy PE.

Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1426-34.PMID: 12657576 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced recombinant adeno-associated virus-mediated vascular endothelial growth factor expression in the adult mouse retina: a potential model for diabetic retinopathy.

Rakoczy PE, Brankov M, Fonceca A, Zaknich T, Rae BC, Lai CM.

Diabetes. 2003 Mar;52(3):857-63.PMID: 12606531 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus and adeno-associated virus vectors.

Lai CM, Lai YK, Rakoczy PE.

DNA Cell Biol. 2002 Dec;21(12):895-913. Review.PMID: 12573049 [PubMed - indexed for MEDLINE]Related articles

Inhibition of corneal neovascularization by recombinant adenovirus mediated antisense VEGF RNA.

Lai CM, Spilsbury K, Brankov M, Zaknich T, Rakoczy PE.

Exp Eye Res. 2002 Dec;75(6):625-34.PMID: 12470964 [PubMed - indexed for MEDLINE]Related articles

Adeno-associated virus-mediated vascular endothelial growth factor gene therapy in skeletal muscle before transplantation promotes revascularization of regenerating muscle.

Smythe GM, Lai MC, Grounds MD, Rakoczy PE.

Tissue Eng. 2002 Oct;8(5):879-91.PMID: 12459067 [PubMed - indexed for MEDLINE]Related articles

Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model.

Rakoczy PE, Zhang D, Robertson T, Barnett NL, Papadimitriou J, Constable IJ, Lai CM.

Am J Pathol. 2002 Oct;161(4):1515-24.PMID: 12368224 [PubMed - indexed for MEDLINE]Related articlesFree article

The microarray: potential applications for ophthalmic research.

Wilson AS, Hobbs BG, Speed TP, Rakoczy PE.

Mol Vis. 2002 Jul 17;8:259-70. Review.PMID: 12131875 [PubMed - indexed for MEDLINE]Related articlesFree article

Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy.

Lai YK, Shen WY, Brankov M, Lai CM, Constable IJ, Rakoczy PE.

Gene Ther. 2002 Jun;9(12):804-13.PMID: 12040462 [PubMed - indexed for MEDLINE]Related articlesFree article

A model for a blinding eye disease of the aged.

Zhang D, Lai MC, Constable IJ, Rakoczy PE.

Biogerontology. 2002;3(1-2):61-6.PMID: 12014844 [PubMed - indexed for MEDLINE]Related articles

Preclinical evaluation of a phosphorothioate oligonucleotide in the retina of rhesus monkey.

Shen WY, Garrett KL, Wang CG, Zhang K, Ma ZZ, Constable IJ, Rakoczy PE.

Lab Invest. 2002 Feb;82(2):167-82.PMID: 11850530 [PubMed - indexed for MEDLINE]Related articles

The potential of marrow stromal cells in stem cell therapy.

Kicic A, Shen W, Rakoczy PE.

Eye (Lond). 2001 Dec;15(Pt 6):695-707. Review. No abstract available. PMID: 11826986 [PubMed - indexed for MEDLINE]Related articles

The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides.

Chirila TV, Rakoczy PE, Garrett KL, Lou X, Constable IJ.

Biomaterials. 2002 Jan;23(2):321-42. Review.PMID: 11761152 [PubMed - indexed for MEDLINE]Related articles

Uptake dynamics and retinal tolerance of phosphorothioate oligonucleotide and its direct delivery into the site of choroidal neovascularization through subretinal administration in the rat.

Shen WY, Rakoczy PE.

Antisense Nucleic Acid Drug Dev. 2001 Aug;11(4):257-64.PMID: 11572602 [PubMed - indexed for MEDLINE]Related articles

In vivo use of oligonucleotides to inhibit choroidal neovascularisation in the eye.

Garrett KL, Shen WY, Rakoczy PE.

J Gene Med. 2001 Jul-Aug;3(4):373-83.PMID: 11529667 [PubMed - indexed for MEDLINE]Related articles

Combined effect of cyclosporine and sirolimus on improving the longevity of recombinant adenovirus-mediated transgene expression in the retina.

Shen WY, Lai MC, Beilby J, Barnett NL, Liu J, Constable IJ, Rakoczy PE.

Arch Ophthalmol. 2001 Jul;119(7):1033-43.PMID: 11448325 [PubMed - indexed for MEDLINE]Related articles