PubMed

rAAV.sFlt-1 gene therapy achieves lasting reversal of retinal neovascularization in the absence of a strong immune response to the viral vector.

Lai CM, Estcourt MJ, Wikstrom M, Himbeck RP, Barnett NL, Brankov M, Tee LB, Dunlop SA, Degli-Esposti MA, Rakoczy EP.

Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4279-87. Epub 2009 Apr 8.PMID: 19357358 [PubMed - indexed for MEDLINE]Related articles

VEGF-induced choroidal damage in a murine model of retinal neovascularisation.

Tee LB, Penrose MA, O'Shea JE, Lai CM, Rakoczy EP, Dunlop SA.

Br J Ophthalmol. 2008 Jun;92(6):832-8.PMID: 18523088 [PubMed - indexed for MEDLINE]Related articles

Morphological aspects related to long-term functional improvement of the retina in the 4 years following rAAV-mediated gene transfer in the RPE65 null mutation dog.

Narfström K, Seeliger M, Lai CM, Vaegan, Katz M, Rakoczy EP, Remé C.

Adv Exp Med Biol. 2008;613:139-46. No abstract available. PMID: 18188938 [PubMed - indexed for MEDLINE]Related articles

Laser photocoagulation: ocular research and therapy in diabetic retinopathy.

Graham CE, Binz N, Shen WY, Constable IJ, Rakoczy EP.

Adv Exp Med Biol. 2006;572:195-200. Review. No abstract available. PMID: 17249575 [PubMed - indexed for MEDLINE]Related articles

Early vascular and neuronal changes in a VEGF transgenic mouse model of retinal neovascularization.

van Eeden PE, Tee LB, Lukehurst S, Lai CM, Rakoczy EP, Beazley LD, Dunlop SA.

Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4638-45.PMID: 17003462 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition.

Parekh HS, Marano RJ, Rakoczy EP, Blanchfield J, Toth I.

Bioorg Med Chem. 2006 Jul 15;14(14):4775-80. Epub 2006 Apr 5.PMID: 16603365 [PubMed - indexed for MEDLINE]Related articles

Assessment of structure and function over a 3-year period after gene transfer in RPE65-/- dogs.

Narfström K, Vaegan, Katz M, Bragadottir R, Rakoczy EP, Seeliger M.

Doc Ophthalmol. 2005 Jul;111(1):39-48. Epub 2006 Feb 25.PMID: 16502306 [PubMed - indexed for MEDLINE]Related articles

Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys.

Lai CM, Shen WY, Brankov M, Lai YK, Barnett NL, Lee SY, Yeo IY, Mathur R, Ho JE, Pineda P, Barathi A, Ang CL, Constable IJ, Rakoczy EP.

Mol Ther. 2005 Oct;12(4):659-68.PMID: 16023893 [PubMed - indexed for MEDLINE]Related articles

Generation of transgenic mice with mild and severe retinal neovascularisation.

Lai CM, Dunlop SA, May LA, Gorbatov M, Brankov M, Shen WY, Binz N, Lai YK, Graham CE, Barry CJ, Constable IJ, Beazley LD, Rakoczy EP.

Br J Ophthalmol. 2005 Jul;89(7):911-6.PMID: 15965177 [PubMed - indexed for MEDLINE]Related articlesFree article

Development and evaluation of the specificity of a cathepsin D proximal promoter in the eye.

Sutanto EN, Zhang D, Lai YK, Shen WY, Rakoczy EP.

Curr Eye Res. 2005 Jan;30(1):53-61.PMID: 15875365 [PubMed - indexed for MEDLINE]Related articles

Syntheses of polycationic dendrimers on lipophilic peptide core for complexation and transport of oligonucleotides.

Wimmer N, Marano RJ, Kearns PS, Rakoczy EP, Toth I.

Bioorg Med Chem Lett. 2002 Sep 16;12(18):2635-7.PMID: 12182876 [PubMed - indexed for MEDLINE]Related articles