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A Haplotype at the UCP1 Gene Locus Contributes to Genetic Risk for Type 2 Diabetes in Asian Indians (CURES-72).

Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Rao MR, Mohan V.

Metab Syndr Relat Disord. 2009 Nov 29. [Epub ahead of print]PMID: 19943796 [PubMed - as supplied by publisher]Related articles

Association of the PPARGC1A Gene Polymorphism With Diabetic Nephropathy in an Asian Indian Population (CURES-41).

Gayathri SB, Radha V, Vimaleswaran KS, Mohan V.

Metab Syndr Relat Disord. 2009 Nov 9. [Epub ahead of print]PMID: 19900151 [PubMed - as supplied by publisher]Related articles

Evidence for an association with type 2 diabetes mellitus at the PPARG locus in a South Indian population.

Vimaleswaran KS, Radha V, Jayapriya MG, Ghosh S, Majumder PP, Rao MR, Mohan V.

Metabolism. 2009 Oct 19. [Epub ahead of print]PMID: 19846173 [PubMed - as supplied by publisher]Related articles

Association of uncoupling protein 2 and 3 gene polymorphisms with type 2 diabetes in Asian Indians.

Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Rao MR, Mohan V.

J Endocrinol Invest. 2009 Sep 30. [Epub ahead of print]PMID: 19794301 [PubMed - as supplied by publisher]Related articles

Identification of novel variants in the hepatocyte nuclear factor-1alpha gene in South Indian patients with maturity onset diabetes of young.

Radha V, Ek J, Anuradha S, Hansen T, Pedersen O, Mohan V.

J Clin Endocrinol Metab. 2009 Jun;94(6):1959-65. Epub 2009 Mar 31.PMID: 19336507 [PubMed - indexed for MEDLINE]Related articles

The guanine nucleotide exchange factor, C3G regulates differentiation and survival of human neuroblastoma cells.

Radha V, Rajanna A, Gupta RK, Dayma K, Raman T.

J Neurochem. 2008 Dec;107(5):1424-35. Epub 2008 Oct 24.PMID: 18957052 [PubMed - indexed for MEDLINE]Related articles

A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians.

Vimaleswaran KS, Radha V, Ramya K, Babu HN, Savitha N, Roopa V, Monalisa D, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V.

Hum Genet. 2008 Jul;123(6):599-605. Epub 2008 May 9.PMID: 18465144 [PubMed - indexed for MEDLINE]Related articles

Absence of Association of Metabolic Syndrome with PPARGC1A, PPARG and UCP1 Gene Polymorphisms in Asian Indians.

Vimaleswaran KS, Radha V, Deepa R, Mohan V.

Metab Syndr Relat Disord. 2007 Jun;5(2):153-62.PMID: 18370824 [PubMed - in process]Related articles

In vivo radioprotection by 5-aminosalicylic acid.

Mantena SK, Unnikrishnan MK, Joshi R, Radha V, Devi PU, Mukherjee T.

Mutat Res. 2008 Jan 31;650(1):63-79. Epub 2007 Oct 23.PMID: 18155638 [PubMed - indexed for MEDLINE]Related articles

The rs12255372(G/T) and rs7903146(C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians.

Bodhini D, Radha V, Dhar M, Narayani N, Mohan V.

Metabolism. 2007 Sep;56(9):1174-8.PMID: 17697858 [PubMed - indexed for MEDLINE]Related articles

Gene-environment interactions and the diabetes epidemic in India.

Mohan V, Sudha V, Radhika G, Radha V, Rema M, Deepa R.

Forum Nutr. 2007;60:118-26. Review.PMID: 17684408 [PubMed - indexed for MEDLINE]Related articles

Regulation of p73 by Hck through kinase-dependent and independent mechanisms.

Paliwal P, Radha V, Swarup G.

BMC Mol Biol. 2007 May 30;8:45.PMID: 17535448 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic predisposition to type 2 diabetes among Asian Indians.

Radha V, Mohan V.

Indian J Med Res. 2007 Mar;125(3):259-74.PMID: 17496355 [PubMed - indexed for MEDLINE]Related articlesFree article

C3G is required for c-Abl-induced filopodia and its overexpression promotes filopodia formation.

Radha V, Rajanna A, Mitra A, Rangaraj N, Swarup G.

Exp Cell Res. 2007 Jul 1;313(11):2476-92. Epub 2007 Mar 30. Erratum in: Exp Cell Res. 2007 Sep 10;313(15):3376. PMID: 17475248 [PubMed - indexed for MEDLINE]Related articles

A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants.

Chalasani ML, Radha V, Gupta V, Agarwal N, Balasubramanian D, Swarup G.

Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1607-14.PMID: 17389490 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of association between serum adiponectin levels and the Pro12Ala polymorphism in Asian Indians.

Radha V, Vimaleswaran KS, Babu S, Deepa R, Anjana M, Ghosh S, Majumder PP, Rao MR, Mohan V.

Diabet Med. 2007 Apr;24(4):398-402. Epub 2007 Feb 28.PMID: 17335469 [PubMed - indexed for MEDLINE]Related articles

Association of lipoprotein lipase gene polymorphisms with obesity and type 2 diabetes in an Asian Indian population.

Radha V, Vimaleswaran KS, Ayyappa KA, Mohan V.

Int J Obes (Lond). 2007 Jun;31(6):913-8. Epub 2007 Feb 13.PMID: 17299379 [PubMed - indexed for MEDLINE]Related articles

Thr54 allele carriers of the Ala54Thr variant of FABP2 gene have associations with metabolic syndrome and hypertriglyceridemia in urban South Indians.

Vimaleswaran KS, Radha V, Mohan V.

Metabolism. 2006 Sep;55(9):1222-6.PMID: 16919542 [PubMed - indexed for MEDLINE]Related articles

Involvement of caspase 1 and its activator Ipaf upstream of mitochondrial events in apoptosis.

Thalappilly S, Sadasivam S, Radha V, Swarup G.

FEBS J. 2006 Jun;273(12):2766-78.PMID: 16817903 [PubMed - indexed for MEDLINE]Related articles

The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians.

Bodhini D, Radha V, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V.

Int J Obes (Lond). 2007 Jan;31(1):97-102. Epub 2006 Apr 25.PMID: 16652127 [PubMed - indexed for MEDLINE]Related articles

Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: Evidence for heterogeneity.

Radha V, Vimaleswaran KS, Babu HN, Abate N, Chandalia M, Satija P, Grundy SM, Ghosh S, Majumder PP, Deepa R, Rao SM, Mohan V.

Diabetes Care. 2006 May;29(5):1046-51.PMID: 16644635 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of lipoprotein lipase Hind III and Ser 447 Ter polymorphisms with dyslipidemia in Asian Indians.

Radha V, Mohan V, Vidya R, Ashok AK, Deepa R, Mathias RA.

Am J Cardiol. 2006 May 1;97(9):1337-42. Epub 2006 Mar 20.PMID: 16635607 [PubMed - indexed for MEDLINE]Related articles

Effect of polymorphisms in the PPARGC1A gene on body fat in Asian Indians.

Vimaleswaran KS, Radha V, Anjana M, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V.

Int J Obes (Lond). 2006 Jun;30(6):884-91.PMID: 16446747 [PubMed - indexed for MEDLINE]Related articles

Rage gene promoter polymorphisms and diabetic retinopathy in a clinic-based population from South India.

Ramprasad S, Radha V, Mathias RA, Majumder PP, Rao MR, Rema M.

Eye (Lond). 2007 Mar;21(3):395-401. Epub 2006 Jan 27.PMID: 16440015 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor-gamma co-activator-1alpha (PGC-1alpha) gene polymorphisms and their relationship to Type 2 diabetes in Asian Indians.

Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Deepa R, Babu HN, Rao MR, Mohan V.

Diabet Med. 2005 Nov;22(11):1516-21.PMID: 16241916 [PubMed - indexed for MEDLINE]Related articles

A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor-1alpha is associated with maturity-onset diabetes of the young and younger age at onset of type 2 diabetes in Asian Indians.

Anuradha S, Radha V, Deepa R, Hansen T, Carstensen B, Pedersen O, Mohan V.

Diabetes Care. 2005 Oct;28(10):2430-5.PMID: 16186275 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of p73 in regulating human caspase-1 gene transcription induced by interferon-{gamma} and cisplatin.

Jain N, Gupta S, Sudhakar Ch, Radha V, Swarup G.

J Biol Chem. 2005 Nov 4;280(44):36664-73. Epub 2005 Aug 31.PMID: 16135520 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomics and proteomics of Type 2 diabetes in Indians.

Mohan V, Balasubramanyam M, Radha V.

J Assoc Physicians India. 2005 Jun;53:507-9. No abstract available. PMID: 16121803 [PubMed - indexed for MEDLINE]Related articles

Association of low adiponectin levels with the metabolic syndrome--the Chennai Urban Rural Epidemiology Study (CURES-4).

Mohan V, Deepa R, Pradeepa R, Vimaleswaran KS, Mohan A, Velmurugan K, Radha V.

Metabolism. 2005 Apr;54(4):476-81.PMID: 15798954 [PubMed - indexed for MEDLINE]Related articles

ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes.

Abate N, Chandalia M, Satija P, Adams-Huet B, Grundy SM, Sandeep S, Radha V, Deepa R, Mohan V.

Diabetes. 2005 Apr;54(4):1207-13.PMID: 15793263 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the fatty acid-binding protein 2 and apolipoprotein C-III genes are associated with the metabolic syndrome and dyslipidemia in a South Indian population.

Guettier JM, Georgopoulos A, Tsai MY, Radha V, Shanthirani S, Deepa R, Gross M, Rao G, Mohan V.

J Clin Endocrinol Metab. 2005 Mar;90(3):1705-11. Epub 2004 Dec 14.PMID: 15598690 [PubMed - indexed for MEDLINE]Related articlesFree article

Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis.

Sadasivam S, Gupta S, Radha V, Batta K, Kundu TK, Swarup G.

Oncogene. 2005 Jan 20;24(4):627-36.PMID: 15580302 [PubMed - indexed for MEDLINE]Related articles

Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton.

Radha V, Rajanna A, Swarup G.

BMC Cell Biol. 2004 Aug 20;5:31.PMID: 15320955 [PubMed - indexed for MEDLINE]Related articlesFree article

The genetics of diabetes mellitus.

Radha V, Vimaleswaran KS, Deepa R, Mohan V.

Indian J Med Res. 2003 Jun;117:225-38. Review.PMID: 14748467 [PubMed - indexed for MEDLINE]Related articles

Physical and functional interaction between Hck tyrosine kinase and guanine nucleotide exchange factor C3G results in apoptosis, which is independent of C3G catalytic domain.

Shivakrupa R, Radha V, Sudhakar Ch, Swarup G.

J Biol Chem. 2003 Dec 26;278(52):52188-94. Epub 2003 Oct 9.PMID: 14551197 [PubMed - indexed for MEDLINE]Related articlesFree article

A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis.

Gupta S, Radha V, Sudhakar Ch, Swarup G.

FEBS Lett. 2002 Dec 4;532(1-2):61-6.PMID: 12459463 [PubMed - indexed for MEDLINE]Related articles

Genes and diabetic retinopathy.

Radha V, Rema M, Mohan V.

Indian J Ophthalmol. 2002 Mar;50(1):5-11. Review.PMID: 12090088 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of cytochrome c release and apoptosis by Hck-SH3 domain-mediated signalling requires caspase-3.

Radha V, Sudhakar Ch, Ray P, Swarup G.

Apoptosis. 2002 Jun;7(3):195-207.PMID: 11997663 [PubMed - indexed for MEDLINE]Related articles

A nuclear protein tyrosine phosphatase induces shortening of G1 phase and increase in c-Myc protein level.

Ganapati U, Gupta S, Radha V, Sudhakar C, Manogaran PS, Swarup G.

Exp Cell Res. 2001 Apr 15;265(1):1-10.PMID: 11281638 [PubMed - indexed for MEDLINE]Related articles

Direct transcriptional activation of human caspase-1 by tumor suppressor p53.

Gupta S, Radha V, Furukawa Y, Swarup G.

J Biol Chem. 2001 Apr 6;276(14):10585-8. Epub 2001 Feb 13.PMID: 11278253 [PubMed - indexed for MEDLINE]Related articlesFree article

PTP-S2, a nuclear tyrosine phosphatase, is phosphorylated and excluded from condensed chromosomes during mitosis.

Nambirajan S, Radha V, Kamatkar S, Swarup G.

J Biosci. 2000 Mar;25(1):33-40.PMID: 10824196 [PubMed - indexed for MEDLINE]Related articles

Induction of p53 dependent apoptosis upon overexpression of a nuclear protein tyrosine phosphatase.

Radha V, Sudhakar C, Swarup G.

FEBS Lett. 1999 Jun 25;453(3):308-12.PMID: 10405166 [PubMed - indexed for MEDLINE]Related articles

Overexpression of a nuclear protein tyrosine phosphatase increases cell proliferation.

Radha V, Nambirajan S, Swarup G.

FEBS Lett. 1997 Jun 2;409(1):33-6.PMID: 9199498 [PubMed - indexed for MEDLINE]Related articles

Two splice variants of a tyrosine phosphatase differ in substrate specificity, DNA binding, and subcellular location.

Kamatkar S, Radha V, Nambirajan S, Reddy RS, Swarup G.

J Biol Chem. 1996 Oct 25;271(43):26755-61.PMID: 8900155 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of Lyn tyrosine kinase with the nuclear matrix and cell-cycle-dependent changes in matrix-associated tyrosine kinase activity.

Radha V, Nambirajan S, Swarup G.

Eur J Biochem. 1996 Mar 1;236(2):352-9.PMID: 8612602 [PubMed - indexed for MEDLINE]Related articlesFree article

Subcellular localization of a protein-tyrosine phosphatase: evidence for association with chromatin.

Radha V, Nambirajan S, Swarup G.

Biochem J. 1994 Apr 1;299 ( Pt 1):41-7.PMID: 8166658 [PubMed - indexed for MEDLINE]Related articlesFree article

Stabilization of a protein-tyrosine phosphatase mRNA upon mitogenic stimulation of T-lymphocytes.

Rajendrakumar GV, Radha V, Swarup G.

Biochim Biophys Acta. 1993 Nov 16;1216(2):205-12.PMID: 8241261 [PubMed - indexed for MEDLINE]Related articles

Binding of a protein-tyrosine phosphatase to DNA through its carboxy-terminal noncatalytic domain.

Radha V, Kamatkar S, Swarup G.

Biochemistry. 1993 Mar 9;32(9):2194-201.PMID: 8443161 [PubMed - indexed for MEDLINE]Related articles

Molecular cloning and expression of a protein-tyrosine phosphatase showing homology with transcription factors Fos and Jun.

Swarup G, Kamatkar S, Radha V, Rema V.

FEBS Lett. 1991 Mar 11;280(1):65-9.PMID: 1849097 [PubMed - indexed for MEDLINE]Related articles

Essential fatty acids and peptic ulcer disease.

Das UN, Reddy DN, Rao PN, Radha V.

Gut. 1988 Jan;29(1):134. No abstract available. PMID: 18668889 [PubMed - as supplied by publisher]Related articlesFree article