PubMed

DNA repair in human fibroblasts, as reflected by host-cell reactivation of a transfected UV-irradiated luciferase gene, is not related to donor age.

Merkle TJ, O'Brien K, Brooks PJ, Tarone RE, Robbins JH.

Mutat Res. 2004 Oct 4;554(1-2):9-17.PMID: 15450399 [PubMed - indexed for MEDLINE]Related articles

Adult-onset xeroderma pigmentosum neurological disease--observations in an autopsy case.

Robbins JH, Kraemer KH, Merchant SN, Brumback RA.

Clin Neuropathol. 2002 Jan-Feb;21(1):18-23.PMID: 11846040 [PubMed - indexed for MEDLINE]Related articles

A 32P-postlabeling assay for the oxidative DNA lesion 8,5'-cyclo-2'-deoxyadenosine in mammalian tissues: evidence that four type II I-compounds are dinucleotides containing the lesion in the 3' nucleotide.

Randerath K, Zhou GD, Somers RL, Robbins JH, Brooks PJ.

J Biol Chem. 2001 Sep 21;276(38):36051-7. Epub 2001 Jul 13.PMID: 11454870 [PubMed - indexed for MEDLINE]Related articlesFree article

Cockayne syndrome and xeroderma pigmentosum.

Rapin I, Lindenbaum Y, Dickson DW, Kraemer KH, Robbins JH.

Neurology. 2000 Nov 28;55(10):1442-9. Review.PMID: 11185579 [PubMed - indexed for MEDLINE]Related articles

The oxidative DNA lesion 8,5'-(S)-cyclo-2'-deoxyadenosine is repaired by the nucleotide excision repair pathway and blocks gene expression in mammalian cells.

Brooks PJ, Wise DS, Berry DA, Kosmoski JV, Smerdon MJ, Somers RL, Mackie H, Spoonde AY, Ackerman EJ, Coleman K, Tarone RE, Robbins JH.

J Biol Chem. 2000 Jul 21;275(29):22355-62.PMID: 10801836 [PubMed - indexed for MEDLINE]Related articlesFree article

DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and cockayne syndrome resemble xeroderma pigmentosum cells.

Moriwaki S, Stefanini M, Lehmann AR, Hoeijmakers JH, Robbins JH, Rapin I, Botta E, Tanganelli B, Vermeulen W, Broughton BC, Kraemer KH.

J Invest Dermatol. 1996 Oct;107(4):647-53.PMID: 8823375 [PubMed - indexed for MEDLINE]Related articles

Fluorescent light-induced chromatid breaks distinguish Alzheimer disease cells from normal cells in tissue culture.

Parshad RP, Sanford KK, Price FM, Melnick LK, Nee LE, Schapiro MB, Tarone RE, Robbins JH.

Proc Natl Acad Sci U S A. 1996 May 14;93(10):5146-50.PMID: 8643543 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene specific DNA repair of damage induced in familial Alzheimer disease cells by ultraviolet irradiation or by nitrogen mustard.

Link CJ Jr, Robbins JH, Bohr VA.

Mutat Res. 1995 Mar;336(2):115-21.PMID: 7885382 [PubMed - indexed for MEDLINE]Related articles

Gene-specific DNA repair in xeroderma pigmentosum complementation groups A, C, D, and F. Relation to cellular survival and clinical features.

Evans MK, Robbins JH, Ganges MB, Tarone RE, Nairn RS, Bohr VA.

J Biol Chem. 1993 Mar 5;268(7):4839-47.PMID: 8444862 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinically asymptomatic xeroderma pigmentosum neurological disease in an adult: evidence for a neurodegeneration in later life caused by defective DNA repair.

Robbins JH, Brumback RA, Moshell AN.

Eur Neurol. 1993;33(3):188-90.PMID: 8467834 [PubMed - indexed for MEDLINE]Related articles

Skin cancer and chromosomal aberrations induced by ultraviolet radiation. Evidence for lack of correlation in xeroderma pigmentosum variant and group E patients.

Seguin LR, Ganges MB, Tarone RE, Robbins JH.

Cancer Genet Cytogenet. 1992 Jun;60(2):111-6.PMID: 1606553 [PubMed - indexed for MEDLINE]Related articles

Xeroderma pigmentosum complementation group H is withdrawn and reassigned to group D.

Robbins JH.

Hum Genet. 1991 Dec;88(2):242. No abstract available. PMID: 1757099 [PubMed - indexed for MEDLINE]Related articles

Evidence for defective repair of cyclobutane pyrimidine dimers with normal repair of other DNA photoproducts in a transcriptionally active gene transfected into Cockayne syndrome cells.

Barrett SF, Robbins JH, Tarone RE, Kraemer KH.

Mutat Res. 1991 Nov;255(3):281-91.PMID: 1719400 [PubMed - indexed for MEDLINE]Related articles

Neurological disease in xeroderma pigmentosum. Documentation of a late onset type of the juvenile onset form.

Robbins JH, Brumback RA, Mendiones M, Barrett SF, Carl JR, Cho S, Denckla MB, Ganges MB, Gerber LH, Guthrie RA, et al.

Brain. 1991 Jun;114 ( Pt 3):1335-61.PMID: 2065254 [PubMed - indexed for MEDLINE]Related articles

Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.

Papathanasiou MA, Kerr NC, Robbins JH, McBride OW, Alamo I Jr, Barrett SF, Hickson ID, Fornace AJ Jr.

Mol Cell Biol. 1991 Feb;11(2):1009-16.PMID: 1990262 [PubMed - indexed for MEDLINE]Related articlesFree article

No lack of complementation for unscheduled DNA synthesis between xeroderma pigmentosum complementation groups D and H.

Robbins JH.

Hum Genet. 1989 Dec;84(1):99-101. No abstract available. PMID: 2606486 [PubMed - indexed for MEDLINE]Related articles

A childhood neurodegeneration due to defective DNA repair: a novel concept of disease based on studies xeroderma pigmentosum.

Robbins JH.

J Child Neurol. 1989 Apr;4(2):143-6. Review. No abstract available. PMID: 2654275 [PubMed - indexed for MEDLINE]Related articles

Radiosensitive Down syndrome lymphoblastoid lines have normal ionizing-radiation-induced inhibition of DNA synthesis.

Ganges MB, Tarone RE, Jiang HX, Hauser C, Robbins JH.

Mutat Res. 1988 Nov;194(3):251-6.PMID: 2972926 [PubMed - indexed for MEDLINE]Related articles

Xeroderma pigmentosum. Defective DNA repair causes skin cancer and neurodegeneration.

Robbins JH.

JAMA. 1988 Jul 15;260(3):384-8. No abstract available. PMID: 3379749 [PubMed - indexed for MEDLINE]Related articles

Ultraviolet light-induced chromosomal aberrations in cultured cells from Cockayne syndrome and complementation group C xeroderma pigmentosum patients: lack of correlation with cancer susceptibility.

Seguin LR, Tarone RE, Liao KH, Robbins JH.

Am J Hum Genet. 1988 Mar;42(3):468-75.PMID: 3348214 [PubMed - indexed for MEDLINE]Related articlesFree article

Alzheimer's disease fibroblasts have normal repair of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage determined by the alkaline elution technique.

Kinsella TJ, Dobson PP, Fornace AJ Jr, Barrett SF, Ganges MB, Robbins JH.

Biochem Biophys Res Commun. 1987 Dec 16;149(2):355-61.PMID: 3426578 [PubMed - indexed for MEDLINE]Related articles

Radiation sensitivity of fibroblast strains from patients with Usher's syndrome, Duchenne muscular dystrophy, and Huntington's disease.

Nove J, Tarone RE, Little JB, Robbins JH.

Mutat Res. 1987 Jul;184(1):29-38.PMID: 2955220 [PubMed - indexed for MEDLINE]Related articles

Incorrect priority claim for the DNA-damage hypothesis.

Robbins JH.

Arch Neurol. 1987 Jun;44(6):579-83. No abstract available. PMID: 3579674 [PubMed - indexed for MEDLINE]Related articles

Parkinson's disease, twins, and the DNA-damage hypothesis.

Robbins JH.

Ann Neurol. 1987 Apr;21(4):412. No abstract available. PMID: 3579227 [PubMed - indexed for MEDLINE]Related articles

Ionizing-radiation-induced damage in the DNA of cultured human cells. Identification of 8,5-cyclo-2-deoxyguanosine.

Dizdaroglu M, Dirksen ML, Jiang HX, Robbins JH.

Biochem J. 1987 Feb 1;241(3):929-32.PMID: 3496079 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of DNA-damaging agents on Down syndrome cells: implications for defective DNA-repair mechanisms.

Tarone RE, Liao KH, Robbins JH.

Prog Clin Biol Res. 1987;246:93-113. Review. No abstract available. PMID: 2958883 [PubMed - indexed for MEDLINE]Related articles

Alzheimer disease fibroblasts are hypersensitive to the lethal effects of a DNA-damaging chemical.

Scudiero DA, Polinsky RJ, Brumback RA, Tarone RE, Nee LE, Robbins JH.

Mutat Res. 1986 Jan-Feb;159(1-2):125-31.PMID: 3941662 [PubMed - indexed for MEDLINE]Related articles

Cockayne syndrome: clinicopathologic and tissue culture studies of affected siblings.

Leech RW, Brumback RA, Miller RH, Otsuka F, Tarone RE, Robbins JH.

J Neuropathol Exp Neurol. 1985 Sep;44(5):507-19.PMID: 4031953 [PubMed - indexed for MEDLINE]Related articles

Parkinson's disease and Alzheimer's disease: hypersensitivity to X rays in cultured cell lines.

Robbins JH, Otsuka F, Tarone RE, Polinsky RJ, Brumback RA, Nee LE.

J Neurol Neurosurg Psychiatry. 1985 Sep;48(9):916-23.PMID: 3876409 [PubMed - indexed for MEDLINE]Related articlesFree article

The Cockayne syndrome--an inherited multisystem disorder with cutaneous photosensitivity and defective repair of DNA. Comparison with xeroderma pigmentosum.

Otsuka F, Robbins JH.

Am J Dermatopathol. 1985 Aug;7(4):387-92. No abstract available. PMID: 3842793 [PubMed - indexed for MEDLINE]Related articles

Hypersensitivity to ionizing radiation in cultured cells from Down syndrome patients.

Otsuka F, Tarone RE, Seguin LR, Robbins JH.

J Neurol Sci. 1985 May-Jun;69(1-2):103-12.PMID: 3159854 [PubMed - indexed for MEDLINE]Related articles

Hypersensitivity to DNA-damaging agents in abiotrophies: a new explanation for degeneration of neurons, photoreceptors, and muscle in Alzheimer, Parkinson and Huntington diseases, retinitis pigmentosa, and Duchenne muscular dystrophy.

Robbins JH, Brumback RA, Polinsky RJ, Wirtschafter JD, Tarone RE, Scudiero DA, Otsuka F.

Basic Life Sci. 1985;35:315-44. No abstract available. PMID: 2933027 [PubMed - indexed for MEDLINE]Related articles

A sensitive assay for detecting hypersensitivity to ionizing radiation in lymphoblastoid lines from patients with Duchenne muscular dystrophy and primary neuronal degenerations.

Tarone RE, Otsuka F, Robbins JH.

J Neurol Sci. 1984 Sep;65(3):367-81.PMID: 6333487 [PubMed - indexed for MEDLINE]Related articles

Use of lymphoblastoid cell lines to evaluate the hypersensitivity to ultraviolet radiation in Cockayne syndrome.

Otsuka F, Tarone RE, Cayeux S, Robbins JH.

J Invest Dermatol. 1984 May;82(5):480-4.PMID: 6096450 [PubMed - indexed for MEDLINE]Related articles

Hypersensitivity to DNA-damaging agents in cultured cells from patients with Usher's syndrome and Duchenne muscular dystrophy.

Robbins JH, Scudiero DA, Otsuka F, Tarone RE, Brumback RA, Wirtschafter JD, Polinsky RJ, Barrett SF, Moshell AN, Scarpinato RG, et al.

J Neurol Neurosurg Psychiatry. 1984 Apr;47(4):391-8.PMID: 6726265 [PubMed - indexed for MEDLINE]Related articlesFree article

Statistical methods for in vitro cell survival assays.

Tarone RE, Scudiero DA, Robbins JH.

Mutat Res. 1983 Sep;111(1):79-96.PMID: 6621576 [PubMed - indexed for MEDLINE]Related articles

Evidence that lack of deoxyribonucleic acid repair causes death of neurons in xeroderma pigmentosum.

Robbins JH, Polinsky RJ, Moshell AN.

Ann Neurol. 1983 Jun;13(6):682-4.PMID: 6881931 [PubMed - indexed for MEDLINE]Related articles

Host cell reactivation by fibroblasts from patients with pigmentary degeneration of the retina.

Lytle CD, Tarone RE, Barrett SF, Wirtschafter JD, Dupuy JM, Robbins JH.

Photochem Photobiol. 1983 May;37(5):503-8. No abstract available. PMID: 6878443 [PubMed - indexed for MEDLINE]Related articles

Radiosensitivity in alzheimer disease and Parkinson disease.

Robbins JH, Otsuka F, Tarone RE, Polinsky RJ, Brumback RA, Moshell AN, Nee LE, Ganges MB, Cayeux SJ.

Lancet. 1983 Feb 26;1(8322):468-9. No abstract available. PMID: 6131182 [PubMed - indexed for MEDLINE]Related articles

Lymphoblastoid lines and skin fibroblasts from patients with tuberous sclerosis are abnormally sensitive to ionizing radiation and to a radiomimetic chemical.

Scudiero DA, Moshell AN, Scarpinato RG, Meyer SA, Clatterbuck BE, Tarone RE, Robbins JH.

J Invest Dermatol. 1982 Mar;78(3):234-8.PMID: 7057056 [PubMed - indexed for MEDLINE]Related articles

Hypersensitivity to N-methyl-N'-nitro-N-nitrosoguanidine in fibroblasts from patients with Huntington disease, familial dysautonomia, and other primary neuronal degenerations.

Scudiero DA, Meyer SA, Clatterbuck BE, Tarone RE, Robbins JH.

Proc Natl Acad Sci U S A. 1981 Oct;78(10):6451-5.PMID: 6458814 [PubMed - indexed for MEDLINE]Related articlesFree article

A simple and rapid method for evaluating the survival of xeroderma pigmentosum lymphoid lines after irradiation with ultraviolet light.

Moshell AN, Tarone RE, Newfield SA, Andrews AD, Robbins JH.

In Vitro. 1981 Apr;17(4):299-307.PMID: 6263790 [PubMed - indexed for MEDLINE]Related articles

The post-UV colony-forming ability of normal fibroblast strains and of the xeroderma pigmentosum group G strain.

Barrett SF, Tarone RE, Moshell AN, Ganges MB, Robbins JH.

J Invest Dermatol. 1981 Jan;76(1):59-62.PMID: 7462668 [PubMed - indexed for MEDLINE]Related articles

Human fibroblast strain with normal survival but abnormal postreplication repair after ultraviolet light irradiation.

Doniger J, Barrett SF, Robbins JH.

Cancer Res. 1980 Aug;40(8 Pt 1):2736-9.PMID: 7388823 [PubMed - indexed for MEDLINE]Related articlesFree article

Radiosensitivity in Huntington's disease: implications for pathogenesis and presymptomatic diagnosis.

Moshell AN, Tarone RE, Barrett SF, Robbins JH.

Lancet. 1980 Jan 5;1(8158):9-11.PMID: 6101401 [PubMed - indexed for MEDLINE]Related articles

Yearly review: new forms of diseases with DNA repair defects.

Robbins JH.

Photochem Photobiol. 1979 Dec;30(6):739-41. Review. No abstract available. PMID: 394167 [PubMed - indexed for MEDLINE]Related articles

DNA repair processes protect human beings from premature solar skin damage: evidence from studies on xeroderma pigmentosum.

Robbins JH, Moshell AN.

J Invest Dermatol. 1979 Jul;73(1):102-7.PMID: 448168 [PubMed - indexed for MEDLINE]Related articles

Significance of repair of human DNA: evidence from studies of xeroderma pigmentosum.

Robbins JH.

J Natl Cancer Inst. 1978 Sep;61(3):645-56. No abstract available. PMID: 278844 [PubMed - indexed for MEDLINE]Related articles

Normal pressure hydrocephalus. Recognition and relationship to neurological abnormalities in Cockayne's syndrome.

Brumback RA, Yoder FW, Andrews AD, Peck GL, Robbins JH.

Arch Neurol. 1978 Jun;35(6):337-45.PMID: 655905 [PubMed - indexed for MEDLINE]Related articles

Ultraviolet light-induced sister chromatid exchanges in xeroderma pigmentosum and in Cockayne's syndrome lymphocyte cell lines.

Cheng WS, Tarone RE, Andrews AD, Whang-Peng JS, Robbins JH.

Cancer Res. 1978 Jun;38(6):1601-9. No abstract available. PMID: 647673 [PubMed - indexed for MEDLINE]Related articlesFree article