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Pancreatic duct replication is increased with obesity and type 2 diabetes in humans.

Butler AE, Galasso R, Matveyenko A, Rizza RA, Dry S, Butler PC.

Diabetologia. 2009 Oct 21. [Epub ahead of print]PMID: 19844672 [PubMed - as supplied by publisher]Related articles

Application of isotopic techniques using constant specific activity or enrichment to the study of carbohydrate metabolism.

Vella A, Rizza RA.

Diabetes. 2009 Oct;58(10):2168-74. No abstract available. PMID: 19794073 [PubMed - indexed for MEDLINE]Related articles

MINIMAL MODEL ASSESSMENT OF HEPATIC INSULIN EXTRACTION DURING AN ORAL TEST FROM STANDARD INSULIN KINETIC PARAMETERS.

Campioni M, Toffolo GM, Basu R, Rizza RA, Cobelli C.

Am J Physiol Endocrinol Metab. 2009 Aug 11. [Epub ahead of print]PMID: 19671837 [PubMed - as supplied by publisher]Related articles

Fatty acid metabolism in the elderly: effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women.

Koutsari C, Ali AH, Nair KS, Rizza RA, O'Brien P, Khosla S, Jensen MD.

J Clin Endocrinol Metab. 2009 Sep;94(9):3414-23. Epub 2009 Jun 30.PMID: 19567532 [PubMed - indexed for MEDLINE]Related articles

Additional evidence that transaldolase exchange, isotope discrimination during the triose-isomerase reaction, or both occur in humans: effects of type 2 diabetes.

Basu R, Chandramouli V, Schumann W, Basu A, Landau BR, Rizza RA.

Diabetes. 2009 Jul;58(7):1539-43. Epub 2009 Apr 14.PMID: 19366865 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of type 2 diabetes on insulin secretion, insulin action, glucose effectiveness, and postprandial glucose metabolism.

Basu A, Dalla Man C, Basu R, Toffolo G, Cobelli C, Rizza RA.

Diabetes Care. 2009 May;32(5):866-72. Epub 2009 Feb 5.PMID: 19196896 [PubMed - indexed for MEDLINE]Related articlesFree article

Prandial insulin and the systemic appearance of meal-derived glucose in people with type 1 diabetes.

Vella A, Shah P, Basu A, Rizza RA.

Diabetes Care. 2008 Nov;31(11):2230-1. No abstract available. PMID: 18955720 [PubMed - indexed for MEDLINE]Related articlesFree article

Dipeptidyl peptidase-4 inhibition by vildagliptin and the effect on insulin secretion and action in response to meal ingestion in type 2 diabetes.

Dalla Man C, Bock G, Giesler PD, Serra DB, Ligueros Saylan M, Foley JE, Camilleri M, Toffolo G, Cobelli C, Rizza RA, Vella A.

Diabetes Care. 2009 Jan;32(1):14-8. Epub 2008 Oct 17.PMID: 18931099 [PubMed - in process]Related articlesFree article

Liver is the site of splanchnic cortisol production in obese nondiabetic humans.

Basu R, Basu A, Grudzien M, Jung P, Jacobson P, Johnson M, Singh R, Sarr M, Rizza RA.

Diabetes. 2009 Jan;58(1):39-45. Epub 2008 Oct 13. Erratum in: Diabetes. 2009 Aug;58(8):1936. PMID: 18852327 [PubMed - indexed for MEDLINE]Related articlesFree article

Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements.

Henderson GC, Dhatariya K, Ford GC, Klaus KA, Basu R, Rizza RA, Jensen MD, Khosla S, O'Brien P, Nair KS.

FASEB J. 2009 Feb;23(2):631-41. Epub 2008 Sep 30.PMID: 18827019 [PubMed - indexed for MEDLINE]Related articles

Relationship between pancreatic vesicular monoamine transporter 2 (VMAT2) and insulin expression in human pancreas.

Saisho Y, Harris PE, Butler AE, Galasso R, Gurlo T, Rizza RA, Butler PC.

J Mol Histol. 2008 Oct;39(5):543-51. Epub 2008 Sep 13.PMID: 18791800 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of pioglitazone and metformin on NEFA-induced insulin resistance in type 2 diabetes.

Basu R, Basu A, Chandramouli V, Norby B, Dicke B, Shah P, Cohen O, Landau BR, Rizza RA.

Diabetologia. 2008 Nov;51(11):2031-40. Epub 2008 Sep 4.PMID: 18769904 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of labeled oral minimal model to measure hepatic insulin sensitivity.

Man CD, Toffolo G, Basu R, Rizza RA, Cobelli C.

Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1152-9. Epub 2008 Sep 2.PMID: 18765681 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma C5 glucose-to-2H2O ratio does not provide an accurate assessment of gluconeogenesis during hyperinsulinemic-euglycemic clamps in either nondiabetic or diabetic humans.

Basu R, Chandramouli V, Dicke B, Landau BR, Rizza RA.

Diabetes. 2008 Jul;57(7):1800-4. Epub 2008 Apr 16.PMID: 18420484 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans.

Meier JJ, Butler AE, Saisho Y, Monchamp T, Galasso R, Bhushan A, Rizza RA, Butler PC.

Diabetes. 2008 Jun;57(6):1584-94. Epub 2008 Mar 11.PMID: 18334605 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of dipeptidyl peptidase-4 inhibition on gastric volume, satiation and enteroendocrine secretion in type 2 diabetes: a double-blind, placebo-controlled crossover study.

Vella A, Bock G, Giesler PD, Burton DB, Serra DB, Saylan ML, Deacon CF, Foley JE, Rizza RA, Camilleri M.

Clin Endocrinol (Oxf). 2008 Nov;69(5):737-44. Epub 2008 Mar 10.PMID: 18331607 [PubMed - indexed for MEDLINE]Related articles

A model of glucose production during a meal.

Dalla Man C, Toffolo G, Basu R, Rizza RA, Cobelli C.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:5647-50.PMID: 17946713 [PubMed - indexed for MEDLINE]Related articles

Mixed meal simulation model of glucose-insulin system.

Dalla Man C, Rizza RA, Cobelli C.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:307-10.PMID: 17946394 [PubMed - indexed for MEDLINE]Related articles

Evidence that processes other than gluconeogenesis may influence the ratio of deuterium on the fifth and third carbons of glucose: implications for the use of 2H2O to measure gluconeogenesis in humans.

Bock G, Schumann WC, Basu R, Burgess SC, Yan Z, Chandramouli V, Rizza RA, Landau BR.

Diabetes. 2008 Jan;57(1):50-5. Epub 2007 Oct 12.PMID: 17934142 [PubMed - indexed for MEDLINE]Related articlesFree article

Meal simulation model of the glucose-insulin system.

Dalla Man C, Rizza RA, Cobelli C.

IEEE Trans Biomed Eng. 2007 Oct;54(10):1740-9.PMID: 17926672 [PubMed - indexed for MEDLINE]Related articles

Comparison of the effects of pioglitazone and metformin on hepatic and extra-hepatic insulin action in people with type 2 diabetes.

Basu R, Shah P, Basu A, Norby B, Dicke B, Chandramouli V, Cohen O, Landau BR, Rizza RA.

Diabetes. 2008 Jan;57(1):24-31. Epub 2007 Oct 3.PMID: 17914032 [PubMed - indexed for MEDLINE]Related articlesFree article

Splanchnic spillover of extracellular lipase-generated fatty acids in overweight and obese humans.

Nelson RH, Basu R, Johnson CM, Rizza RA, Miles JM.

Diabetes. 2007 Dec;56(12):2878-84. Epub 2007 Sep 19.PMID: 17881612 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type-2 diabetes.

Saisho Y, Butler AE, Meier JJ, Monchamp T, Allen-Auerbach M, Rizza RA, Butler PC.

Clin Anat. 2007 Nov;20(8):933-42.PMID: 17879305 [PubMed - indexed for MEDLINE]Related articlesFree article

Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis.

Butler AE, Galasso R, Meier JJ, Basu R, Rizza RA, Butler PC.

Diabetologia. 2007 Nov;50(11):2323-31. Epub 2007 Sep 6.PMID: 17805509 [PubMed - indexed for MEDLINE]Related articles

Beneficial effects of GLP-1 on endothelial function in humans: dampening by glyburide but not by glimepiride.

Basu A, Charkoudian N, Schrage W, Rizza RA, Basu R, Joyner MJ.

Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1289-95. Epub 2007 Aug 21.PMID: 17711996 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycemic variation and hypoglycemia in patients with well-controlled type 1 diabetes on a multiple daily insulin injection program with use of glargine and ultralente as basal insulin.

Kudva YC, Basu A, Jenkins GD, Pons GM, Vogelsang DA, Rizza RA, Smith SA, Isley WL.

Endocr Pract. 2007 May-Jun;13(3):244-50.PMID: 17599855 [PubMed - indexed for MEDLINE]Related articles

Progression from newly acquired impaired fasting glucose to type 2 diabetes: response to Nichols et al.

Dinneen SF, Rizza RA.

Diabetes Care. 2007 Jul;30(7):e79; author reply e80. No abstract available. PMID: 17596502 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects.

Basu R, Pajvani UB, Rizza RA, Scherer PE.

Diabetes. 2007 Aug;56(8):2174-7. Epub 2007 May 18.PMID: 17513700 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men.

Basu R, Dalla Man C, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA.

Diabetes Care. 2007 Aug;30(8):1972-8. Epub 2007 May 11.PMID: 17496236 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of an effect of pioglitazone or glipizide on lipoprotein-associated phospholipase A2 in type 2 diabetes.

Basu A, Jensen MD, McCann F, Nandy D, Mukhopadhyay D, McConnell JP, Rizza RA.

Endocr Pract. 2007 Mar-Apr;13(2):147-52.PMID: 17490928 [PubMed - indexed for MEDLINE]Related articles

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes.

Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA, Butler PC.

Diabetes. 2007 Aug;56(8):2016-27. Epub 2007 May 2.PMID: 17475933 [PubMed - indexed for MEDLINE]Related articlesFree article

GIM, simulation software of meal glucose-insulin model.

Dalla Man C, Raimondo DM, Rizza RA, Cobelli C.

J Diabetes Sci Technol. 2007 May;1(3):323-30.PMID: 19885087 [PubMed]Free article

Hematopoietic stem cells derived from adult donors are not a source of pancreatic beta-cells in adult nondiabetic humans.

Butler AE, Huang A, Rao PN, Bhushan A, Hogan WJ, Rizza RA, Butler PC.

Diabetes. 2007 Jul;56(7):1810-6. Epub 2007 Apr 24.PMID: 17456852 [PubMed - indexed for MEDLINE]Related articlesFree article

Contribution of hepatic and extrahepatic insulin resistance to the pathogenesis of impaired fasting glucose: role of increased rates of gluconeogenesis.

Bock G, Chittilapilly E, Basu R, Toffolo G, Cobelli C, Chandramouli V, Landau BR, Rizza RA.

Diabetes. 2007 Jun;56(6):1703-11. Epub 2007 Mar 23.PMID: 17384334 [PubMed - indexed for MEDLINE]Related articlesFree article

Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women.

Basu R, Dalla Man C, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA.

Diabetes. 2007 Mar;56(3):753-66. Erratum in: Diabetes. 2007 May;56(5):1486. PMID: 17327446 [PubMed - indexed for MEDLINE]Related articlesFree article

Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: a randomized trial.

Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, O'Brien PC, Johnson MG, Williams AR, Cutshall SM, Mundy LM, Rizza RA, McMahon MM.

Ann Intern Med. 2007 Feb 20;146(4):233-43.PMID: 17310047 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of dipeptidyl peptidase-4 inhibition on gastrointestinal function, meal appearance, and glucose metabolism in type 2 diabetes.

Vella A, Bock G, Giesler PD, Burton DB, Serra DB, Saylan ML, Dunning BE, Foley JE, Rizza RA, Camilleri M.

Diabetes. 2007 May;56(5):1475-80. Epub 2007 Feb 15.PMID: 17303799 [PubMed - indexed for MEDLINE]Related articlesFree article

Prediction of postprandial glycemic exposure: utility of fasting and 2-h glucose measurements alone and in combination with assessment of body composition, fitness, and strength.

Cohen O, Basu R, Bock G, Dalla Man C, Campioni M, Basu A, Toffolo G, Cobelli C, Rizza RA.

Diabetes Care. 2006 Dec;29(12):2708-13.PMID: 17130209 [PubMed - indexed for MEDLINE]Related articlesFree article

Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11beta hydroxysteroid dehydrogenase type 1 activity.

Basu R, Edgerton DS, Singh RJ, Cherrington A, Rizza RA.

Diabetes. 2006 Nov;55(11):3013-9.PMID: 17065337 [PubMed - indexed for MEDLINE]Related articlesFree article

DHEA in elderly women and DHEA or testosterone in elderly men.

Nair KS, Rizza RA, O'Brien P, Dhatariya K, Short KR, Nehra A, Vittone JL, Klee GG, Basu A, Basu R, Cobelli C, Toffolo G, Dalla Man C, Tindall DJ, Melton LJ 3rd, Smith GE, Khosla S, Jensen MD.

N Engl J Med. 2006 Oct 19;355(16):1647-59.PMID: 17050889 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased islet beta cell replication adjacent to intrapancreatic gastrinomas in humans.

Meier JJ, Butler AE, Galasso R, Rizza RA, Butler PC.

Diabetologia. 2006 Nov;49(11):2689-96. Epub 2006 Sep 23.PMID: 17016695 [PubMed - indexed for MEDLINE]Related articles

Modeling chronic glycemic exposure variables as correlates and predictors of microvascular complications of diabetes.

Dyck PJ, Davies JL, Clark VM, Litchy WJ, Dyck PJ, Klein CJ, Rizza RA, Pach JM, Klein R, Larson TS, Melton LJ 3rd, O'Brien PC.

Diabetes Care. 2006 Oct;29(10):2282-8.PMID: 17003307 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of duration of type 2 diabetes mellitus on insulin secretion.

Zangeneh F, Arora PS, Dyck PJ, Bekris L, Lernmark A, Achenbach SJ, Oberg AL, Rizza RA.

Endocr Pract. 2006 Jul-Aug;12(4):388-93.PMID: 16939949 [PubMed - indexed for MEDLINE]Related articles

Incretin effect potentiates beta-cell responsivity to glucose as well as to its rate of change: OGTT and matched intravenous study.

Campioni M, Toffolo G, Shuster LT, Service FJ, Rizza RA, Cobelli C.

Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E54-60. Epub 2006 Jul 25.PMID: 16868229 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of age and sex on postprandial glucose metabolism: differences in glucose turnover, insulin secretion, insulin action, and hepatic insulin extraction.

Basu R, Dalla Man C, Campioni M, Basu A, Klee G, Toffolo G, Cobelli C, Rizza RA.

Diabetes. 2006 Jul;55(7):2001-14. Erratum in: Diabetes. 2006 Sep;55(9):2665. PMID: 16804069 [PubMed - indexed for MEDLINE]Related articlesFree article

Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association.

Eckel RH, Kahn R, Robertson RM, Rizza RA.

Diabetes Care. 2006 Jul;29(7):1697-9. No abstract available. PMID: 16801605 [PubMed - indexed for MEDLINE]Related articlesFree article

Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association.

Eckel RH, Kahn R, Robertson RM, Rizza RA.

Circulation. 2006 Jun 27;113(25):2943-6. No abstract available. PMID: 16801475 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinically confirmed type 2 diabetes mellitus and colorectal cancer risk: a population-based, retrospective cohort study.

Limburg PJ, Vierkant RA, Fredericksen ZS, Leibson CL, Rizza RA, Gupta AK, Ahlquist DA, Melton LJ 3rd, Sellers TA, Cerhan JR.

Am J Gastroenterol. 2006 Aug;101(8):1872-9. Epub 2006 Jun 22.PMID: 16790032 [PubMed - indexed for MEDLINE]Related articles

Renal amino acid, fat and glucose metabolism in type 1 diabetic and non-diabetic humans: effects of acute insulin withdrawal.

Moller N, Jensen MD, Rizza RA, Andrews JC, Nair KS.

Diabetologia. 2006 Aug;49(8):1901-8. Epub 2006 May 23.PMID: 16718465 [PubMed - indexed for MEDLINE]Related articles

Relationship between beta-cell mass and fasting blood glucose concentration in humans.

Ritzel RA, Butler AE, Rizza RA, Veldhuis JD, Butler PC.

Diabetes Care. 2006 Mar;29(3):717-8. No abstract available. PMID: 16505537 [PubMed - indexed for MEDLINE]Related articlesFree article