PubMed

Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography.

Fischer MD, Huber G, Beck SC, Tanimoto N, Muehlfriedel R, Fahl E, Grimm C, Wenzel A, Remé CE, van de Pavert SA, Wijnholds J, Pacal M, Bremner R, Seeliger MW.

PLoS One. 2009 Oct 19;4(10):e7507.PMID: 19838301 [PubMed - in process]Related articlesFree article

Cooperative phagocytes: resident microglia and bone marrow immigrants remove dead photoreceptors in retinal lesions.

Joly S, Francke M, Ulbricht E, Beck S, Seeliger M, Hirrlinger P, Hirrlinger J, Lang KS, Zinkernagel M, Odermatt B, Samardzija M, Reichenbach A, Grimm C, Remé CE.

Am J Pathol. 2009 Jun;174(6):2310-23. Epub 2009 May 12.PMID: 19435787 [PubMed - indexed for MEDLINE]Related articles

Müller cell response to blue light injury of the rat retina.

Iandiev I, Wurm A, Hollborn M, Wiedemann P, Grimm C, Remé CE, Reichenbach A, Pannicke T, Bringmann A.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3559-67. Epub 2008 Apr 30.PMID: 18450590 [PubMed - indexed for MEDLINE]Related articlesFree article

Localization of glial aquaporin-4 and Kir4.1 in the light-injured murine retina.

Iandiev I, Pannicke T, Hollborn M, Wiedemann P, Reichenbach A, Grimm C, Remé CE, Bringmann A.

Neurosci Lett. 2008 Apr 4;434(3):317-21. Epub 2008 Feb 16.PMID: 18328627 [PubMed - indexed for MEDLINE]Related articles

R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal.

Samardzija M, von Lintig J, Tanimoto N, Oberhauser V, Thiersch M, Remé CE, Seeliger M, Grimm C, Wenzel A.

Hum Mol Genet. 2008 Jan 15;17(2):281-92. Epub 2007 Oct 12.PMID: 17933883 [PubMed - indexed for MEDLINE]Related articlesFree article

Rpe65 as a modifier gene for inherited retinal degeneration.

Samardzija M, Wenzel A, Naash M, Remé CE, Grimm C.

Eur J Neurosci. 2006 Feb;23(4):1028-34.PMID: 16519667 [PubMed - indexed for MEDLINE]Related articles

Continuous expression of the homeobox gene Pax6 in the ageing human retina.

Stanescu D, Iseli HP, Schwerdtfeger K, Ittner LM, Remé CE, Hafezi F.

Eye (Lond). 2007 Jan;21(1):90-3. Epub 2005 Oct 28.PMID: 16254589 [PubMed - indexed for MEDLINE]Related articles

The dark side of light: rhodopsin and the silent death of vision the proctor lecture.

Remé CE.

Invest Ophthalmol Vis Sci. 2005 Aug;46(8):2671-82. No abstract available. PMID: 16043837 [PubMed - indexed for MEDLINE]Related articlesFree article

[Survival factors in the treatment of hereditary retinal degeneration]

Frigg R, Wenzel A, Grimm C, Remé CE.

Ophthalmologe. 2005 Aug;102(8):757-63. Review. German. PMID: 15990984 [PubMed - indexed for MEDLINE]Related articles

The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light.

Wenzel A, Oberhauser V, Pugh EN Jr, Lamb TD, Grimm C, Samardzija M, Fahl E, Seeliger MW, Remé CE, von Lintig J.

J Biol Chem. 2005 Aug 19;280(33):29874-84. Epub 2005 Jun 16.PMID: 15961402 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration.

Wenzel A, Grimm C, Samardzija M, Remé CE.

Prog Retin Eye Res. 2005 Mar;24(2):275-306. Epub 2004 Nov 11. Review.PMID: 15610977 [PubMed - indexed for MEDLINE]Related articles

The nob mutation does not protect against light-induced retinal degeneration.

Pardue MT, Grimm C, Wenzel A, Remé CE.

Adv Exp Med Biol. 2003;533:327-30. No abstract available. PMID: 15180280 [PubMed - indexed for MEDLINE]Related articles

New retinal light damage QTL in mice with the light-sensitive RPE65 LEU variant.

Danciger M, Lyon J, Worrill D, Hoffman S, Lem J, Reme CE, Wenzel A, Grimm C.

Mamm Genome. 2004 Apr;15(4):277-83.PMID: 15112105 [PubMed - indexed for MEDLINE]Related articles

The dangers of seeing light in the dark.

Remé CE, Wenzel A.

Nat Genet. 2003 Oct;35(2):115-6. No abstract available. PMID: 14517534 [PubMed - indexed for MEDLINE]Related articles

The genetic modifier Rpe65Leu(450): effect on light damage susceptibility in c-Fos-deficient mice.

Wenzel A, Grimm C, Samardzija M, Remé CE.

Invest Ophthalmol Vis Sci. 2003 Jun;44(6):2798-802.PMID: 12766089 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased light damage susceptibility at night does not correlate with RPE65 levels and rhodopsin regeneration in rats.

Beatrice J, Wenzel A, Remé CE, Grimm C.

Exp Eye Res. 2003 Jun;76(6):695-700.PMID: 12742352 [PubMed - indexed for MEDLINE]Related articles

Why study rod cell death in retinal degenerations and how?

Remé CE, Grimm C, Hafezi F, Iseli HP, Wenzel A.

Doc Ophthalmol. 2003 Jan;106(1):25-9. Review.PMID: 12675482 [PubMed - indexed for MEDLINE]Related articles

Light damage susceptibility and RPE65 in rats.

Iseli HP, Wenzel A, Hafezi F, REme CE, Grimm C.

Exp Eye Res. 2002 Oct;75(4):407-13.PMID: 12387788 [PubMed - indexed for MEDLINE]Related articles

Evidence for two apoptotic pathways in light-induced retinal degeneration.

Hao W, Wenzel A, Obin MS, Chen CK, Brill E, Krasnoperova NV, Eversole-Cire P, Kleyner Y, Taylor A, Simon MI, Grimm C, Remé CE, Lem J.

Nat Genet. 2002 Oct;32(2):254-60. Epub 2002 Sep 3.PMID: 12219089 [PubMed - indexed for MEDLINE]Related articles

HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration.

Grimm C, Wenzel A, Groszer M, Mayser H, Seeliger M, Samardzija M, Bauer C, Gassmann M, Remé CE.

Nat Med. 2002 Jul;8(7):718-24. Epub 2002 Jun 17.PMID: 12068288 [PubMed - indexed for MEDLINE]Related articles

Fra-1 substitutes for c-Fos in AP-1-mediated signal transduction in retinal apoptosis.

Wenzel A, Iseli HP, Fleischmann A, Hafezi F, Grimm C, Wagner EF, Remé CE.

J Neurochem. 2002 Mar;80(6):1089-94.PMID: 11953459 [PubMed - indexed for MEDLINE]Related articles

Localization of organic anion transport protein 2 in the apical region of rat retinal pigment epithelium.

Gao B, Wenzel A, Grimm C, Vavricka SR, Benke D, Meier PJ, Remè CE.

Invest Ophthalmol Vis Sci. 2002 Feb;43(2):510-4.PMID: 11818398 [PubMed - indexed for MEDLINE]Related articlesFree article

New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis.

Seeliger MW, Grimm C, Ståhlberg F, Friedburg C, Jaissle G, Zrenner E, Guo H, Remé CE, Humphries P, Hofmann F, Biel M, Fariss RN, Redmond TM, Wenzel A.

Nat Genet. 2001 Sep;29(1):70-4.PMID: 11528395 [PubMed - indexed for MEDLINE]Related articles

AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun.

Grimm C, Wenzel A, Behrens A, Hafezi F, Wagner EF, Remé CE.

Cell Death Differ. 2001 Aug;8(8):859-67.PMID: 11526439 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptosis in the Retina: The Silent Death of Vision.

Remé CE, Grimm C, Hafezi F, Wenzel A, Williams TP.

News Physiol Sci. 2000 Jun;15:120-124.PMID: 11390893 [PubMed - as supplied by publisher]Related articlesFree article

Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor.

Wenzel A, Grimm C, Seeliger MW, Jaissle G, Hafezi F, Kretschmer R, Zrenner E, Remé CE.

Invest Ophthalmol Vis Sci. 2001 Jun;42(7):1653-9.PMID: 11381074 [PubMed - indexed for MEDLINE]Related articlesFree article

The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration.

Wenzel A, Reme CE, Williams TP, Hafezi F, Grimm C.

J Neurosci. 2001 Jan 1;21(1):53-8.PMID: 11150319 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression in the mouse retina: the effect of damaging light.

Grimm C, Wenzel A, Hafezi F, Remé CE.

Mol Vis. 2000 Dec 13;6:252-60.PMID: 11134582 [PubMed - indexed for MEDLINE]Related articlesFree article

Fra-1 replaces c-Fos-dependent functions in mice.

Fleischmann A, Hafezi F, Elliott C, Remé CE, Rüther U, Wagner EF.

Genes Dev. 2000 Nov 1;14(21):2695-700.PMID: 11069886 [PubMed - indexed for MEDLINE]Related articlesFree article

Blue light's effects on rhodopsin: photoreversal of bleaching in living rat eyes.

Grimm C, Remé CE, Rol PO, Williams TP.

Invest Ophthalmol Vis Sci. 2000 Nov;41(12):3984-90.PMID: 11053303 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular ophthalmology: an update on animal models for retinal degenerations and dystrophies.

Hafezi F, Grimm C, Simmen BC, Wenzel A, Remé CE.

Br J Ophthalmol. 2000 Aug;84(8):922-7. Review. No abstract available. PMID: 10906106 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration.

Grimm C, Wenzel A, Hafezi F, Yu S, Redmond TM, Remé CE.

Nat Genet. 2000 May;25(1):63-6.PMID: 10802658 [PubMed - indexed for MEDLINE]Related articles

[Photoreceptor renewal and the pigment epithelium of the retina--congratulations to a pioneer in retinal research: Richard W. Young]

Remé CE.

Klin Monbl Augenheilkd. 2000 Mar;216(3):129-32. German. PMID: 10773975 [PubMed - indexed for MEDLINE]Related articles

[Therapeutic strategies in RP (retinitis pigmentosa): light at the end of the tunnel?]

Abegg M, Hafezi F, Wenzel A, Grimm C, Remé CE.

Klin Monbl Augenheilkd. 2000 Feb;216(2):83-9. Review. German. PMID: 10730223 [PubMed - indexed for MEDLINE]Related articles

The retina of c-fos-/- mice: electrophysiologic, morphologic and biochemical aspects.

Kueng-Hitz N, Grimm C, Lansel N, Hafezi F, He L, Fox DA, Remé CE, Niemeyer G, Wenzel A.

Invest Ophthalmol Vis Sci. 2000 Mar;41(3):909-16.PMID: 10711713 [PubMed - indexed for MEDLINE]Related articlesFree article

c-fos controls the "private pathway" of light-induced apoptosis of retinal photoreceptors.

Wenzel A, Grimm C, Marti A, Kueng-Hitz N, Hafezi F, Niemeyer G, Remé CE.

J Neurosci. 2000 Jan 1;20(1):81-8.PMID: 10627584 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinal photoreceptors are apoptosis-competent in the absence of JunD/AP-1.

Hafezi F, Grimm C, Wenzel A, Abegg M, Yaniv M, Remé CE.

Cell Death Differ. 1999 Oct;6(10):934-6. No abstract available. PMID: 10617374 [PubMed - indexed for MEDLINE]Related articlesFree article

Photoreceptor autophagy: effects of light history on number and opsin content of degradative vacuoles.

Remé CE, Wolfrum U, Imsand C, Hafezi F, Williams TP.

Invest Ophthalmol Vis Sci. 1999 Sep;40(10):2398-404.PMID: 10476808 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors.

Hafezi F, Marti A, Grimm C, Wenzel A, Remé CE.

Vision Res. 1999 Jul;39(15):2511-8.PMID: 10396620 [PubMed - indexed for MEDLINE]Related articles

Retinal degeneration in the rd mouse in the absence of c-fos.

Hafezi F, Abegg M, Grimm C, Wenzel A, Munz K, Stürmer J, Farber DB, Remé CE.

Invest Ophthalmol Vis Sci. 1998 Nov;39(12):2239-44.PMID: 9804131 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptotic cell death in retinal degenerations.

Remé CE, Grimm C, Hafezi F, Marti A, Wenzel A.

Prog Retin Eye Res. 1998 Oct;17(4):443-64. Review.PMID: 9777646 [PubMed - indexed for MEDLINE]Related articles

[HPETE, an arachidonic acid metabolite, induces apoptosis in rat retina in vitro]

Hafezi F, Reinboth JJ, Wenzel A, Munz K, Remé CE.

Klin Monbl Augenheilkd. 1998 Jun;212(6):469-72. German. PMID: 9715468 [PubMed - indexed for MEDLINE]Related articles

Lipofuscin in the retina: quantitative assay for an unprecedented autofluorescent compound (pyridinium bis-retinoid, A2-E) of ocular age pigment.

Reinboth JJ, Gautschi K, Munz K, Eldred GE, Remé CE.

Exp Eye Res. 1997 Nov;65(5):639-43.PMID: 9367643 [PubMed - indexed for MEDLINE]Related articles

Light-induced cell death of retinal photoreceptors in the absence of p53.

Marti A, Hafezi F, Lansel N, Hegi ME, Wenzel A, Grimm C, Niemeyer G, Remé CE.

Invest Ophthalmol Vis Sci. 1998 Apr;39(5):846-9.PMID: 9538895 [PubMed - indexed for MEDLINE]Related articlesFree article

Light-induced apoptosis: differential timing in the retina and pigment epithelium.

Hafezi F, Marti A, Munz K, Remé CE.

Exp Eye Res. 1997 Jun;64(6):963-70.PMID: 9301477 [PubMed - indexed for MEDLINE]Related articles

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo.

Hafezi F, Steinbach JP, Marti A, Munz K, Wang ZQ, Wagner EF, Aguzzi A, Remé CE.

Nat Med. 1997 Mar;3(3):346-9.PMID: 9055866 [PubMed - indexed for MEDLINE]Related articles

Bright light therapy in focus: lamp emission spectra and ocular safety.

Remé CE, Rol P, Grothmann K, Kaase H, Terman M.

Technol Health Care. 1996 Dec;4(4):403-13.PMID: 9042691 [PubMed - indexed for MEDLINE]Related articles

Light elicits the release of docosahexaenoic acid from membrane phospholipids in the rat retina in vitro.

Reinboth JJ, Clausen M, Remé CE.

Exp Eye Res. 1996 Sep;63(3):277-84.PMID: 8943700 [PubMed - indexed for MEDLINE]Related articles

Light damage in the rat retina: glial fibrillary acidic protein accumulates in Müller cells in correlation with photoreceptor damage.

de Raad S, Szczesny PJ, Munz K, Remé CE.

Ophthalmic Res. 1996;28(2):99-107.PMID: 8792360 [PubMed - indexed for MEDLINE]Related articles

Lipid mediators in the rat retina: light exposure and trauma elicit leukotriene B4 release in vitro.

Reinboth JJ, Gautschi K, Clausen M, Remé CE.

Curr Eye Res. 1995 Nov;14(11):1001-8.PMID: 8585927 [PubMed - indexed for MEDLINE]Related articles