PubMed

Non-hepatitis virus associated mixed essential cryoglobulinemia.

Annear NM, Cook HT, Atkins M, Pusey CD, Salama AD.

Kidney Int. 2009 Nov 4. [Epub ahead of print]PMID: 19890273 [PubMed - as supplied by publisher]Related articles

Kallikreins: unravelling the genetics of autoimmune glomerulonephritis.

Behmoaras J, Cook HT, Pusey CD.

Nephrol Dial Transplant. 2009 Oct;24(10):2987-9. Epub 2009 Aug 7. No abstract available. PMID: 19666659 [PubMed - in process]Related articles

Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized trial.

de Groot K, Harper L, Jayne DR, Flores Suarez LF, Gregorini G, Gross WL, Luqmani R, Pusey CD, Rasmussen N, Sinico RA, Tesar V, Vanhille P, Westman K, Savage CO; EUVAS (European Vasculitis Study Group).

Ann Intern Med. 2009 May 19;150(10):670-80.PMID: 19451574 [PubMed - indexed for MEDLINE]Related articlesFree article

Urinary monocyte chemoattractant protein-1 (MCP-1) and connective tissue growth factor (CCN2) as prognostic markers for progression of diabetic nephropathy.

Tam FW, Riser BL, Meeran K, Rambow J, Pusey CD, Frankel AH.

Cytokine. 2009 Jul;47(1):37-42. Epub 2009 May 5.PMID: 19409809 [PubMed - indexed for MEDLINE]Related articles

Mucosal tolerance induced by an immunodominant peptide from rat alpha3(IV)NC1 in established experimental autoimmune glomerulonephritis.

Reynolds J, Abbott DS, Karegli J, Evans DJ, Pusey CD.

Am J Pathol. 2009 Jun;174(6):2202-10. Epub 2009 Apr 30.PMID: 19406992 [PubMed - indexed for MEDLINE]Related articles

Rituximab is effective in the treatment of refractory ophthalmic Wegener's granulomatosis.

Taylor SR, Salama AD, Joshi L, Pusey CD, Lightman SL.

Arthritis Rheum. 2009 May;60(5):1540-7.PMID: 19404964 [PubMed - indexed for MEDLINE]Related articles

P2X7 deficiency attenuates renal injury in experimental glomerulonephritis.

Taylor SR, Turner CM, Elliott JI, McDaid J, Hewitt R, Smith J, Pickering MC, Whitehouse DL, Cook HT, Burnstock G, Pusey CD, Unwin RJ, Tam FW.

J Am Soc Nephrol. 2009 Jun;20(6):1275-81. Epub 2009 Apr 23.PMID: 19389853 [PubMed - indexed for MEDLINE]Related articles

Shining a LAMP on pauci-immune focal segmental glomerulonephritis.

Salama AD, Pusey CD.

Kidney Int. 2009 Jul;76(1):15-7. Epub 2009 Apr 22. Review.PMID: 19387471 [PubMed - indexed for MEDLINE]Related articles

Lymphocytes from P2X7-deficient mice exhibit enhanced P2X7 responses.

Taylor SR, Gonzalez-Begne M, Sojka DK, Richardson JC, Sheardown SA, Harrison SM, Pusey CD, Tam FW, Elliott JI.

J Leukoc Biol. 2009 Jun;85(6):978-86. Epub 2009 Mar 10.PMID: 19276178 [PubMed - indexed for MEDLINE]Related articles

Renal & ocular targets for therapy in Wegener's granulomatosis.

Joshi L, Hamour S, Salama AD, Pusey CD, Lightman S, Taylor SR.

Inflamm Allergy Drug Targets. 2009 Mar;8(1):70-9. Review.PMID: 19275695 [PubMed - indexed for MEDLINE]Related articles

Experimental autoimmune vasculitis: an animal model of anti-neutrophil cytoplasmic autoantibody-associated systemic vasculitis.

Little MA, Smyth L, Salama AD, Mukherjee S, Smith J, Haskard D, Nourshargh S, Cook HT, Pusey CD.

Am J Pathol. 2009 Apr;174(4):1212-20. Epub 2009 Mar 5.PMID: 19264905 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein load impairs factor H binding promoting complement-dependent dysfunction of proximal tubular cells.

Buelli S, Abbate M, Morigi M, Moioli D, Zanchi C, Noris M, Zoja C, Pusey CD, Zipfel PF, Remuzzi G.

Kidney Int. 2009 May;75(10):1050-9. Epub 2009 Feb 25.PMID: 19242507 [PubMed - indexed for MEDLINE]Related articles

Identification of a nephritogenic immunodominant B and T cell epitope in experimental autoimmune glomerulonephritis.

Reynolds J, Haxby J, Juggapah JK, Evans DJ, Pusey CD.

Clin Exp Immunol. 2009 Feb;155(2):311-9. Epub 2008 Nov 25.PMID: 19040602 [PubMed - indexed for MEDLINE]Related articles

Rituximab is effective in the treatment of refractory Churg-Strauss syndrome and is associated with diminished T-cell interleukin-5 production.

Pepper RJ, Fabre MA, Pavesio C, Gaskin G, Jones RB, Jayne D, Pusey CD, Salama AD.

Rheumatology (Oxford). 2008 Jul;47(7):1104-5. Epub 2008 May 20. No abstract available. PMID: 18492710 [PubMed - indexed for MEDLINE]Related articles

Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility.

Behmoaras J, Bhangal G, Smith J, McDonald K, Mutch B, Lai PC, Domin J, Game L, Salama A, Foxwell BM, Pusey CD, Cook HT, Aitman TJ.

Nat Genet. 2008 May;40(5):553-9.PMID: 18443593 [PubMed - indexed for MEDLINE]Related articlesFree article

Transplantation of human fetal mesenchymal stem cells improves glomerulopathy in a collagen type I alpha 2-deficient mouse.

Guillot PV, Cook HT, Pusey CD, Fisk NM, Harten S, Moss J, Shore I, Bou-Gharios G.

J Pathol. 2008 Apr;214(5):627-36.PMID: 18266309 [PubMed - indexed for MEDLINE]Related articles

A case of treated ANCA-associated vasculitis with recurrent renal failure.

Salama AD, Cook HT, Pusey CD, Pepper RJ.

Clin J Am Soc Nephrol. 2008 Mar;3(2):637-45. Epub 2008 Jan 16. No abstract available. PMID: 18199842 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon-beta reduces proteinuria in experimental glomerulonephritis.

Satchell SC, Buchatska O, Khan SB, Bhangal G, Tasman CH, Saleem MA, Baker DP, Lobb RR, Smith J, Cook HT, Mathieson PW, Pusey CD.

J Am Soc Nephrol. 2007 Nov;18(11):2875-84. Epub 2007 Oct 17.PMID: 17942968 [PubMed - indexed for MEDLINE]Related articlesFree article

Platelet-derived growth factor reorganizes the actin cytoskeleton through 3-phosphoinositide-dependent and 3-phosphoinositide-independent mechanisms in human mesangial cells.

Harper L, Kashiwagi Y, Pusey CD, Hendry BM, Domin J.

Nephron Physiol. 2007;107(2):p45-56. Epub 2007 Sep 5.PMID: 17804914 [PubMed - indexed for MEDLINE]Related articles

A patient with suspected miscarriage is found to have hypertension, renal failure, and thrombocytopenia: case outcome.

Laing CM, Roberts R, Lightstone L, Graham A, Cook TH, Summers S, Pusey CD.

BMJ. 2007 Jul 28;335(7612):205-6; discussion 206-8. Review. No abstract available. PMID: 17656546 [PubMed - indexed for MEDLINE]Related articles

Chances of renal recovery for dialysis-dependent ANCA-associated glomerulonephritis.

de Lind van Wijngaarden RA, Hauer HA, Wolterbeek R, Jayne DR, Gaskin G, Rasmussen N, Noël LH, Ferrario F, Waldherr R, Bruijn JA, Bajema IM, Hagen EC, Pusey CD; EUVAS.

J Am Soc Nephrol. 2007 Jul;18(7):2189-97. Erratum in: J Am Soc Nephrol. 2007 Dec;18(12):3206. Pusey, Charles D [added]. PMID: 17596637 [PubMed - indexed for MEDLINE]Related articlesFree article

Randomized trial of plasma exchange or high-dosage methylprednisolone as adjunctive therapy for severe renal vasculitis.

Jayne DR, Gaskin G, Rasmussen N, Abramowicz D, Ferrario F, Guillevin L, Mirapeix E, Savage CO, Sinico RA, Stegeman CA, Westman KW, van der Woude FJ, de Lind van Wijngaarden RA, Pusey CD; European Vasculitis Study Group.

J Am Soc Nephrol. 2007 Jul;18(7):2180-8. Epub 2007 Jun 20.PMID: 17582159 [PubMed - indexed for MEDLINE]Related articlesFree article

Results of endoscopic surgery and intralesional steroid therapy for airway compromise due to tracheobronchial Wegener's granulomatosis.

Nouraei SA, Obholzer R, Ind PW, Salama AD, Pusey CD, Porter F, Howard DJ, Sandhu GS.

Thorax. 2008 Jan;63(1):49-52. Epub 2007 Jun 15.PMID: 17573443 [PubMed - indexed for MEDLINE]Related articles

FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity.

Fanciulli M, Norsworthy PJ, Petretto E, Dong R, Harper L, Kamesh L, Heward JM, Gough SC, de Smith A, Blakemore AI, Froguel P, Owen CJ, Pearce SH, Teixeira L, Guillevin L, Graham DS, Pusey CD, Cook HT, Vyse TJ, Aitman TJ.

Nat Genet. 2007 Jun;39(6):721-3. Epub 2007 May 21.PMID: 17529978 [PubMed - indexed for MEDLINE]Related articlesFree article

Genes expressed by both mesangial cells and bone marrow-derived cells underlie genetic susceptibility to crescentic glomerulonephritis in the rat.

Smith J, Lai PC, Behmoaras J, Roufosse C, Bhangal G, McDaid JP, Aitman T, Tam FW, Pusey CD, Cook HT.

J Am Soc Nephrol. 2007 Jun;18(6):1816-23. Epub 2007 May 2.PMID: 17475818 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis and suppresses monocyte chemoattractant protein-1 but not IL-1beta or IL-6.

Sheryanna A, Bhangal G, McDaid J, Smith J, Manning A, Foxwell BM, Feldmann M, Cook HT, Pusey CD, Tam FW.

J Am Soc Nephrol. 2007 Apr;18(4):1167-79. Epub 2007 Feb 21.PMID: 17314328 [PubMed - indexed for MEDLINE]Related articlesFree article

Urinary proteomic profiles distinguish between active and inactive lupus nephritis.

Mosley K, Tam FW, Edwards RJ, Crozier J, Pusey CD, Lightstone L.

Rheumatology (Oxford). 2006 Dec;45(12):1497-504. Epub 2006 Oct 17.PMID: 17046860 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in experimental and human glomerulonephritis.

Turner CM, Tam FW, Lai PC, Tarzi RM, Burnstock G, Pusey CD, Cook HT, Unwin RJ.

Nephrol Dial Transplant. 2007 Feb;22(2):386-95. Epub 2006 Oct 13.PMID: 17040997 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell therapy for renal regeneration--time for some joined-up thinking?

Poulsom R, Prodromidi EI, Pusey CD, Cook HT.

Nephrol Dial Transplant. 2006 Dec;21(12):3349-53. Epub 2006 Oct 5. Review. No abstract available. PMID: 17023491 [PubMed - indexed for MEDLINE]Related articlesFree article

A nephritogenic peptide induces intermolecular epitope spreading on collagen IV in experimental autoimmune glomerulonephritis.

Chen L, Hellmark T, Pedchenko V, Hudson BG, Pusey CD, Fox JW, Bolton WK.

J Am Soc Nephrol. 2006 Nov;17(11):3076-81. Epub 2006 Sep 27.PMID: 17005930 [PubMed - indexed for MEDLINE]Related articlesFree article

Strain susceptibility to active induction and passive transfer of experimental autoimmune glomerulonephritis in the rat.

Reynolds J, Albouainain A, Duda MA, Evans DJ, Pusey CD.

Nephrol Dial Transplant. 2006 Dec;21(12):3398-408. Epub 2006 Sep 23.PMID: 16998225 [PubMed - indexed for MEDLINE]Related articlesFree article

Drug insight: rituximab in renal disease and transplantation.

Salama AD, Pusey CD.

Nat Clin Pract Nephrol. 2006 Apr;2(4):221-30. Review.PMID: 16932428 [PubMed - indexed for MEDLINE]Related articles

Bone marrow-derived cells contribute to podocyte regeneration and amelioration of renal disease in a mouse model of Alport syndrome.

Prodromidi EI, Poulsom R, Jeffery R, Roufosse CA, Pollard PJ, Pusey CD, Cook HT.

Stem Cells. 2006 Nov;24(11):2448-55. Epub 2006 Jul 27.PMID: 16873763 [PubMed - indexed for MEDLINE]Related articlesFree article

Is there a role for TNF-alpha in anti-neutrophil cytoplasmic antibody-associated vasculitis? Lessons from other chronic inflammatory diseases.

Feldmann M, Pusey CD.

J Am Soc Nephrol. 2006 May;17(5):1243-52. Epub 2006 Apr 19. Review.PMID: 16624928 [PubMed - indexed for MEDLINE]Related articlesFree article

The continuing challenge of anti-neutrophil cytoplasm antibody-associated systemic vasculitis and glomerulonephritis.

Pusey CD.

J Am Soc Nephrol. 2006 May;17(5):1221-3. Epub 2006 Apr 19. Review. No abstract available. PMID: 16624927 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of L-carnitine administration on erythrocyte survival in haemodialysis patients.

Arduini A, Bonomini M, Clutterbuck EJ, Laffan MA, Pusey CD.

Nephrol Dial Transplant. 2006 Sep;21(9):2671-2. Epub 2006 Apr 12. No abstract available. PMID: 16611680 [PubMed - indexed for MEDLINE]Related articlesFree article

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans.

Aitman TJ, Dong R, Vyse TJ, Norsworthy PJ, Johnson MD, Smith J, Mangion J, Roberton-Lowe C, Marshall AJ, Petretto E, Hodges MD, Bhangal G, Patel SG, Sheehan-Rooney K, Duda M, Cook PR, Evans DJ, Domin J, Flint J, Boyle JJ, Pusey CD, Cook HT.

Nature. 2006 Feb 16;439(7078):851-5.PMID: 16482158 [PubMed - indexed for MEDLINE]Related articles

Intravital microscopy in the study of ANCA-associated systemic vasculitis.

Little MA, Pusey CD, Nourshargh S.

Clin Nephrol. 2005 Dec;64(6):465-70. Review.PMID: 16370161 [PubMed - indexed for MEDLINE]Related articles

Anti-proteinase 3 antibody binding to neutrophils as demonstrated by confocal microscopy.

Ambrose LR, Little MA, Nourshargh S, Pusey CD.

Kidney Int. 2005 Dec;68(6):2912-3. No abstract available. PMID: 16316379 [PubMed - indexed for MEDLINE]Related articles

Therapeutic effect of anti-TNF-alpha antibodies in an experimental model of anti-neutrophil cytoplasm antibody-associated systemic vasculitis.

Little MA, Bhangal G, Smyth CL, Nakada MT, Cook HT, Nourshargh S, Pusey CD.

J Am Soc Nephrol. 2006 Jan;17(1):160-9. Epub 2005 Nov 23.PMID: 16306166 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-11 reduces renal injury and glomerular NF-kappa B activity in murine experimental glomerulonephritis.

Lai PC, Smith J, Bhangal G, Chaudhry KA, Chaudhry AN, Keith JC Jr, Tam FW, Pusey CD, Cook HT.

Nephron Exp Nephrol. 2005;101(4):e146-54. Epub 2005 Aug 30.PMID: 16131809 [PubMed - indexed for MEDLINE]Related articles

Glomerulonephritis due to antineutrophil cytoplasm antibody-associated vasculitis: an update on approaches to management.

Little MA, Pusey CD.

Nephrology (Carlton). 2005 Aug;10(4):368-76. Review.PMID: 16109084 [PubMed - indexed for MEDLINE]Related articles

Microscopic polyangiitis.

Smyth L, Gaskin G, Pusey CD.

Semin Respir Crit Care Med. 2004 Oct;25(5):523-33.PMID: 16088496 [PubMed]Related articles

Antineutrophil cytoplasm antibodies directed against myeloperoxidase augment leukocyte-microvascular interactions in vivo.

Little MA, Smyth CL, Yadav R, Ambrose L, Cook HT, Nourshargh S, Pusey CD.

Blood. 2005 Sep 15;106(6):2050-8. Epub 2005 Jun 2.PMID: 15933057 [PubMed - indexed for MEDLINE]Related articlesFree article

Antibody blockade of TNF-alpha reduces inflammation and scarring in experimental crescentic glomerulonephritis.

Khan SB, Cook HT, Bhangal G, Smith J, Tam FW, Pusey CD.

Kidney Int. 2005 May;67(5):1812-20.PMID: 15840028 [PubMed - indexed for MEDLINE]Related articles

Nasal administration of recombinant rat alpha3(IV)NC1 prevents the development of experimental autoimmune glomerulonephritis in the WKY rat.

Reynolds J, Prodromidi EI, Juggapah JK, Abbott DS, Holthaus KA, Kalluri R, Pusey CD.

J Am Soc Nephrol. 2005 May;16(5):1350-9. Epub 2005 Apr 6.PMID: 15814836 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapidly progressive glomerulonephritis: current and evolving treatment strategies.

Little MA, Pusey CD.

J Nephrol. 2004 Nov-Dec;17 Suppl 8:S10-9. Review.PMID: 15599880 [PubMed - indexed for MEDLINE]Related articles

Glomerular T cells are of restricted clonality and express multiple CDR3 motifs across different Vbeta T-cell receptor families in experimental autoimmune glomerulonephritis.

Walters G, Habib AM, Reynolds J, Wu H, Knight JF, Pusey CD.

Nephron Exp Nephrol. 2004;98(3):e71-81.PMID: 15528947 [PubMed - indexed for MEDLINE]Related articles

Clinical features and outcome of patients with both ANCA and anti-GBM antibodies.

Levy JB, Hammad T, Coulthart A, Dougan T, Pusey CD.

Kidney Int. 2004 Oct;66(4):1535-40.PMID: 15458448 [PubMed - indexed for MEDLINE]Related articles

Blockade of the CD154-CD40 costimulatory pathway prevents the development of experimental autoimmune glomerulonephritis.

Reynolds J, Khan SB, Allen AR, Benjamin CD, Pusey CD.

Kidney Int. 2004 Oct;66(4):1444-52.PMID: 15458437 [PubMed - indexed for MEDLINE]Related articles