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COVID-19 outbreak: history, mechanism, transmission, structural studies and therapeutics.
Yesudhas D, Srivastava A, Gromiha MM. Yesudhas D, et al. Infection. 2021 Apr;49(2):199-213. doi: 10.1007/s15010-020-01516-2. Epub 2020 Sep 4. Infection. 2021. PMID: 32886331 Free PMC article.
We survey the history and mechanism of coronaviruses, and the structural characteristics of the spike protein and its key residues responsible for human transmissions. METHODS: We have carried out a systematic review to summarize the origin, transmission and etiolog …
We survey the history and mechanism of coronaviruses, and the structural characteristics of the spike protein and its key resi …
Metabolic Cardiomyopathies and Cardiac Defects in Inherited Disorders of Carbohydrate Metabolism: A Systematic Review.
Conte F, Sam JE, Lefeber DJ, Passier R. Conte F, et al. Int J Mol Sci. 2023 May 11;24(10):8632. doi: 10.3390/ijms24108632. Int J Mol Sci. 2023. PMID: 37239976 Free PMC article. Review.
In this systematic review, we offer a comprehensive overview of IMDs linked to carbohydrate metabolism presenting that present with cardiomyopathies, arrhythmogenic disorders and/or structural cardiac defects. We identified 58 IMDs presenting with cardiac complications: 3 …
In this systematic review, we offer a comprehensive overview of IMDs linked to carbohydrate metabolism presenting that present with cardiomy …
Skin care interventions in infants for preventing eczema and food allergy.
Kelleher MM, Cro S, Cornelius V, Lodrup Carlsen KC, Skjerven HO, Rehbinder EM, Lowe AJ, Dissanayake E, Shimojo N, Yonezawa K, Ohya Y, Yamamoto-Hanada K, Morita K, Axon E, Surber C, Cork M, Cooke A, Tran L, Van Vogt E, Schmitt J, Weidinger S, McClanahan D, Simpson E, Duley L, Askie LM, Chalmers JR, Williams HC, Boyle RJ. Kelleher MM, et al. Cochrane Database Syst Rev. 2021 Feb 5;2(2):CD013534. doi: 10.1002/14651858.CD013534.pub2. Cochrane Database Syst Rev. 2021. PMID: 33545739 Free PMC article. Updated.
Engineered Nanoparticles with Antimicrobial Property.
Reshma VG, Syama S, Sruthi S, Reshma SC, Remya NS, Mohanan PV. Reshma VG, et al. Curr Drug Metab. 2017;18(11):1040-1054. doi: 10.2174/1389200218666170925122201. Curr Drug Metab. 2017. PMID: 28952436 Review.
METHODS: A systematic review of the existing scientific literature is being attempted here which includes the properties and applications of a few nano structured materials for antimicrobial therapy and also the mechanism of action of nanomaterials as antimicrobial agents. …
METHODS: A systematic review of the existing scientific literature is being attempted here which includes the properties and applications of …
Thrombolysis (different doses, routes of administration and agents) for acute ischaemic stroke.
Wardlaw JM, Koumellis P, Liu M. Wardlaw JM, et al. Cochrane Database Syst Rev. 2013 May 31;2013(5):CD000514. doi: 10.1002/14651858.CD000514.pub3. Cochrane Database Syst Rev. 2013. PMID: 23728633 Free PMC article. Review.
DATA COLLECTION AND ANALYSIS: Two review authors independently assessed trial eligibility and quality, and extracted the data using a structured proforma. We cross-checked and resolved discrepancies by discussion to reach consensus. ...
DATA COLLECTION AND ANALYSIS: Two review authors independently assessed trial eligibility and quality, and extracted the data using a str
Systematic review on outcomes used in clinical research on autosomal recessive polycystic kidney disease-are patient-centered outcomes our blind spot?
Gimpel C, Liebau MC, Schaefer F. Gimpel C, et al. Pediatr Nephrol. 2021 Dec;36(12):3841-3851. doi: 10.1007/s00467-021-05192-8. Epub 2021 Aug 12. Pediatr Nephrol. 2021. PMID: 34386850 Free PMC article.
DATA SOURCES AND STUDY ELIGIBILITY CRITERIA: A systematic MEDLINE literature search identified 367 ARPKD studies published since 1990; however, of these 134 were excluded because they did not report any clinical outcomes (e.g. only histopathological, genetic, protein st
DATA SOURCES AND STUDY ELIGIBILITY CRITERIA: A systematic MEDLINE literature search identified 367 ARPKD studies published since 1990; howev …
TRP Channels Interactome as a Novel Therapeutic Target in Breast Cancer.
Saldías MP, Maureira D, Orellana-Serradell O, Silva I, Lavanderos B, Cruz P, Torres C, Cáceres M, Cerda O. Saldías MP, et al. Front Oncol. 2021 Jun 10;11:621614. doi: 10.3389/fonc.2021.621614. eCollection 2021. Front Oncol. 2021. PMID: 34178620 Free PMC article.
Ion channels are the main regulators of cellular functions, conducting ions selectively through a pore-forming structure located in the plasma membrane, protein-protein interactions one of their main regulatory mechanisms. ...
Ion channels are the main regulators of cellular functions, conducting ions selectively through a pore-forming structure located in t …
Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis.
Obonyo NG, Sela DP, Raman S, Rachakonda R, Schneider B, Hoe LES, Fanning JP, Bassi GL, Maitland K, Suen JY, Fraser JF. Obonyo NG, et al. Syst Rev. 2023 Nov 22;12(1):221. doi: 10.1186/s13643-023-02385-0. Syst Rev. 2023. PMID: 37990333 Free PMC article.
OBJECTIVE: This study aimed to systematically review the literature on resuscitation-associated and resuscitation-induced endotheliopathy. METHODS: A predetermined structured search of literature published over an 11-year and 6-month period (1 January 2011 to 31 July 2023) …
OBJECTIVE: This study aimed to systematically review the literature on resuscitation-associated and resuscitation-induced endotheliopathy. M …