PubMed

Sequence variation in SORL1 and dementia risk in Swedes.

Reynolds CA, Hong MG, Eriksson UK, Blennow K, Johansson B, Malmberg B, Berg S, Gatz M, Pedersen NL, Bennet AM, Prince JA.

Neurogenetics. 2009 Aug 4. [Epub ahead of print]PMID: 19653016 [PubMed - as supplied by publisher]Related articles

A survey of ABCA1 sequence variation confirms association with dementia.

Reynolds CA, Hong MG, Eriksson UK, Blennow K, Bennet AM, Johansson B, Malmberg B, Berg S, Wiklund F, Gatz M, Pedersen NL, Prince JA.

Hum Mutat. 2009 Sep;30(9):1348-54.PMID: 19606474 [PubMed - indexed for MEDLINE]Related articles

Strategies and issues in the detection of pathway enrichment in genome-wide association studies.

Hong MG, Pawitan Y, Magnusson PK, Prince JA.

Hum Genet. 2009 Aug;126(2):289-301. Epub 2009 May 1.PMID: 19408013 [PubMed - indexed for MEDLINE]Related articles

Transcriptome-wide assessment of human brain and lymphocyte senescence.

Hong MG, Myers AJ, Magnusson PK, Prince JA.

PLoS One. 2008 Aug 20;3(8):e3024.PMID: 18714388 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic susceptibility sets for Alzheimer's disease identified from diverse candidate loci.

Corder EH, Blennow K, Prince JA.

Rejuvenation Res. 2008 Jun;11(3):667-79.PMID: 18593285 [PubMed - indexed for MEDLINE]Related articles

Evidence that the gene encoding insulin degrading enzyme influences human lifespan.

Hong MG, Reynolds C, Gatz M, Johansson B, Palmer JC, Gu HF, Blennow K, Kehoe PG, de Faire U, Pedersen NL, Prince JA.

Hum Mol Genet. 2008 Aug 1;17(15):2370-8. Epub 2008 Apr 30.PMID: 18448515 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenotype selection for detecting variable genes: a survey of cardiovascular quantitative traits and TNF locus polymorphism.

Hong MG, Bennet AM, de Faire U, Prince JA.

Eur J Hum Genet. 2007 Jun;15(6):685-93. Epub 2007 Mar 14.PMID: 17356550 [PubMed - indexed for MEDLINE]Related articlesFree article

Retrospective analysis of coagulation factor II receptor (F2R) sequence variation and coronary heart disease in hypertensive patients.

Gigante B, Bellis A, Visconti R, Marino M, Morisco C, Trimarco V, Galasso G, Piscione F, De Luca N, Prince JA, de Faire U, Trimarco B.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):1213-9. Epub 2007 Mar 8.PMID: 17347481 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of APOE with Parkinson disease age-at-onset in women.

Buchanan DD, Silburn PA, Prince JA, Mellick GD.

Neurosci Lett. 2007 Jan 16;411(3):185-8. Epub 2006 Nov 17.PMID: 17113231 [PubMed - indexed for MEDLINE]Related articles

Neither sequence variation in the IL-10 gene promoter nor presence of IL-10 protein in the cerebral cortex is associated with Alzheimer's disease.

Culpan D, Prince JA, Matthews S, Palmer L, Hughes A, Love S, Kehoe PG, Wilcock GK.

Neurosci Lett. 2006 Nov 13;408(2):141-5. Epub 2006 Sep 14.PMID: 16973274 [PubMed - indexed for MEDLINE]Related articles

Positive association between risk for late-onset Alzheimer disease and genetic variation in IDE.

Björk BF, Katzov H, Kehoe P, Fratiglioni L, Winblad B, Prince JA, Graff C.

Neurobiol Aging. 2007 Sep;28(9):1374-80. Epub 2006 Jul 31.PMID: 16876916 [PubMed - indexed for MEDLINE]Related articles

The cathepsin D rs17571 polymorphism: effects on CSF tau concentrations in Alzheimer disease.

Riemenschneider M, Blennow K, Wagenpfeil S, Andreasen N, Prince JA, Laws SM, Förstl H, Kurz A.

Hum Mutat. 2006 Jun;27(6):532-7.PMID: 16652347 [PubMed - indexed for MEDLINE]Related articles

Longitudinal memory performance during normal aging: twin association models of APOE and other Alzheimer candidate genes.

Reynolds CA, Prince JA, Feuk L, Brookes AJ, Gatz M, Pedersen NL.

Behav Genet. 2006 Mar;36(2):185-94. Epub 2006 Jan 10.PMID: 16402284 [PubMed - indexed for MEDLINE]Related articles

Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-beta 1-42 and plasma apolipoprotein levels.

Katzov H, Bennet AM, Höglund K, Wiman B, Lütjohann D, Brookes AJ, Andreasen N, Blennow K, De Faire U, Prince JA.

J Hum Genet. 2006;51(3):171-9. Epub 2005 Dec 22.PMID: 16372134 [PubMed - indexed for MEDLINE]Related articles

Towards compendia of negative genetic association studies: an example for Alzheimer disease.

Blomqvist ME, Reynolds C, Katzov H, Feuk L, Andreasen N, Bogdanovic N, Blennow K, Brookes AJ, Prince JA.

Hum Genet. 2006 Mar;119(1-2):29-37. Epub 2005 Dec 8.PMID: 16341549 [PubMed - indexed for MEDLINE]Related articles

Methylenetetrahydrofolate reductase genetic polymorphisms in patients with cataract.

Zetterberg M, Tasa G, Prince JA, Palmér M, Juronen E, Veromann S, Teesalu P, Karlsson JO, Blennow K, Zetterberg H.

Am J Ophthalmol. 2005 Nov;140(5):932-4.PMID: 16310481 [PubMed - indexed for MEDLINE]Related articles

Association of TNF-alpha serum levels and TNFA promoter polymorphisms with risk of myocardial infarction.

Bennet AM, van Maarle MC, Hallqvist J, Morgenstern R, Frostegård J, Wiman B, Prince JA, de Faire U.

Atherosclerosis. 2006 Aug;187(2):408-14. Epub 2005 Oct 21.PMID: 16243340 [PubMed - indexed for MEDLINE]Related articles

Genetic association of CDC2 with cerebrospinal fluid tau in Alzheimer's disease.

Johansson A, Zetterberg H, Hampel H, Buerger K, Prince JA, Minthon L, Wahlund LO, Blennow K.

Dement Geriatr Cogn Disord. 2005;20(6):367-74. Epub 2005 Sep 29.PMID: 16192727 [PubMed - indexed for MEDLINE]Related articles

Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease.

Lehmann DJ, Cortina-Borja M, Warden DR, Smith AD, Sleegers K, Prince JA, van Duijn CM, Kehoe PG.

Am J Epidemiol. 2005 Aug 15;162(4):305-17. Epub 2005 Jul 20. Review.PMID: 16033878 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel single nucleotide polymorphism of the neuropeptide Y (NPY) gene associated with alcohol dependence.

Mottagui-Tabar S, Prince JA, Wahlestedt C, Zhu G, Goldman D, Heilig M.

Alcohol Clin Exp Res. 2005 May;29(5):702-7.PMID: 15897713 [PubMed - indexed for MEDLINE]Related articles

Mutation screening of a haplotype block around the insulin degrading enzyme gene and association with Alzheimer's disease.

Feuk L, McCarthy S, Andersson B, Prince JA, Brookes AJ.

Am J Med Genet B Neuropsychiatr Genet. 2005 Jul 5;136B(1):69-71.PMID: 15858821 [PubMed - indexed for MEDLINE]Related articles

Genetic association analysis: lessons from the study of Alzheimers disease.

Brookes AJ, Prince JA.

Mutat Res. 2005 Jun 3;573(1-2):152-9. Review.PMID: 15829244 [PubMed - indexed for MEDLINE]Related articles

Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.

Blomqvist ME, Chalmers K, Andreasen N, Bogdanovic N, Wilcock GK, Cairns NJ, Feuk L, Brookes AJ, Love S, Blennow K, Kehoe PG, Prince JA.

Neurobiol Aging. 2005 Jun;26(6):795-802.PMID: 15718037 [PubMed - indexed for MEDLINE]Related articles

A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer disease and obesity.

Katzov H, Bennet AM, Kehoe P, Wiman B, Gatz M, Blennow K, Lenhard B, Pedersen NL, de Faire U, Prince JA.

Hum Mol Genet. 2004 Nov 1;13(21):2647-57. Epub 2004 Sep 14.PMID: 15367486 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels.

Gu HF, Efendic S, Nordman S, Ostenson CG, Brismar K, Brookes AJ, Prince JA.

Diabetes. 2004 Aug;53(8):2137-42.PMID: 15277398 [PubMed - indexed for MEDLINE]Related articlesFree article

APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of Abeta42.

Prince JA, Zetterberg H, Andreasen N, Marcusson J, Blennow K.

Neurology. 2004 Jun 8;62(11):2116-8.PMID: 15184629 [PubMed - indexed for MEDLINE]Related articles

Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease.

Blomqvist ME, Silburn PA, Buchanan DD, Andreasen N, Blennow K, Pedersen NL, Brookes AJ, Mellick GD, Prince JA.

Neurogenetics. 2004 Jun;5(2):115-9. Epub 2004 Apr 16.PMID: 15088150 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in CTNNA3 encoding alpha-3 catenin and Alzheimer's disease.

Blomqvist ME, Andreasen N, Bogdanovic N, Blennow K, Brookes AJ, Prince JA.

Neurosci Lett. 2004 Apr 1;358(3):220-2.PMID: 15039120 [PubMed - indexed for MEDLINE]Related articles

Variants of CYP46A1 may interact with age and APOE to influence CSF Abeta42 levels in Alzheimer's disease.

Johansson A, Katzov H, Zetterberg H, Feuk L, Johansson B, Bogdanovic N, Andreasen N, Lenhard B, Brookes AJ, Pedersen NL, Blennow K, Prince JA.

Hum Genet. 2004 May;114(6):581-7. Epub 2004 Mar 18.PMID: 15034781 [PubMed - indexed for MEDLINE]Related articles

Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism.

Katzov H, Chalmers K, Palmgren J, Andreasen N, Johansson B, Cairns NJ, Gatz M, Wilcock GK, Love S, Pedersen NL, Brookes AJ, Blennow K, Kehoe PG, Prince JA.

Hum Mutat. 2004 Apr;23(4):358-67.PMID: 15024730 [PubMed - indexed for MEDLINE]Related articles

Common variants of ACE contribute to variable age-at-onset of Alzheimer's disease.

Kehoe PG, Katzov H, Andreasen N, Gatz M, Wilcock GK, Cairns NJ, Palmgren J, de Faire U, Brookes AJ, Pedersen NL, Blennow K, Prince JA.

Hum Genet. 2004 Apr;114(5):478-83. Epub 2004 Feb 17.PMID: 14986105 [PubMed - indexed for MEDLINE]Related articles

A novel screen for nuclear mitochondrial gene associations with Parkinson's disease.

Mellick GD, Silburn PA, Prince JA, Brookes AJ.

J Neural Transm. 2004 Feb;111(2):191-9. Epub 2003 Dec 12.PMID: 14767722 [PubMed - indexed for MEDLINE]Related articles

Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction.

Bennet AM, Prince JA, Fei GZ, Lyrenäs L, Huang Y, Wiman B, Frostegård J, Faire U.

Atherosclerosis. 2003 Dec;171(2):359-67.PMID: 14644408 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in a haplotype block spanning IDE influences Alzheimer disease.

Prince JA, Feuk L, Gu HF, Johansson B, Gatz M, Blennow K, Brookes AJ.

Hum Mutat. 2003 Nov;22(5):363-71.PMID: 14517947 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial activity in the mapping of functional brain changes in schizophrenia.

Prince JA, Oreland L.

Restor Neurol Neurosci. 1998 Jun;12(2-3):185-93.PMID: 12671314 [PubMed]Related articles

Haplotypes extending across ACE are associated with Alzheimer's disease.

Kehoe PG, Katzov H, Feuk L, Bennet AM, Johansson B, Wiman B, de Faire U, Cairns NJ, Wilcock GK, Brookes AJ, Blennow K, Prince JA.

Hum Mol Genet. 2003 Apr 15;12(8):859-67.PMID: 12668609 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased frequency of a new polymorphism in the cell division cycle 2 (cdc2) gene in patients with Alzheimer's disease and frontotemporal dementia.

Johansson A, Hampel H, Faltraco F, Buerger K, Minthon L, Bogdanovic N, Sjögren M, Zetterberg H, Forsell L, Lilius L, Wahlund LO, Rymo L, Prince JA, Blennow K.

Neurosci Lett. 2003 Apr 3;340(1):69-73.PMID: 12648761 [PubMed - indexed for MEDLINE]Related articles

Further evidence for role of a promoter variant in the TNFRSF6 gene in Alzheimer disease.

Feuk L, Prince JA, Blennow K, Brookes AJ.

Hum Mutat. 2003 Jan;21(1):53-60.PMID: 12497631 [PubMed - indexed for MEDLINE]Related articles

Towards high-throughput genotyping of SNPs by dynamic allele-specific hybridization.

Prince JA, Brookes AJ.

Expert Rev Mol Diagn. 2001 Sep;1(3):352-8.PMID: 11901841 [PubMed - indexed for MEDLINE]Related articles

Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.

Prince JA, Feuk L, Sawyer SL, Gottfries J, Ricksten A, Nägga K, Bogdanovic N, Blennow K, Brookes AJ.

Eur J Hum Genet. 2001 Jun;9(6):437-44.PMID: 11436125 [PubMed - indexed for MEDLINE]Related articlesFree article

SNP association studies in Alzheimer's disease highlight problems for complex disease analysis.

Emahazion T, Feuk L, Jobs M, Sawyer SL, Fredman D, St Clair D, Prince JA, Brookes AJ.

Trends Genet. 2001 Jul;17(7):407-13. Review.PMID: 11418222 [PubMed - indexed for MEDLINE]Related articles

Robust and accurate single nucleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): design criteria and assay validation.

Prince JA, Feuk L, Howell WM, Jobs M, Emahazion T, Blennow K, Brookes AJ.

Genome Res. 2001 Jan;11(1):152-62.PMID: 11156624 [PubMed - indexed for MEDLINE]Related articlesFree article

apolipoprotein-E dependent role for the FAS receptor in early onset Alzheimer's disease: finding of a positive association for a polymorphism in the TNFRSF6 gene.

Feuk L, Prince JA, Breen G, Emahazion T, Carothers A, St Clair D, Brookes AJ.

Hum Genet. 2000 Oct;107(4):391-6.PMID: 11129341 [PubMed - indexed for MEDLINE]Related articles

No association between the alpha2-macroglobulin (A2M) deletion and Alzheimer's disease, and no change in A2M mRNA, protein, or protein expression.

Blennow K, Ricksten A, Prince JA, Brookes AJ, Emahazion T, Wasslavik C, Bogdanovic N, Andreasen N, Båtsman S, Marcusson J, Nägga K, Wallin A, Regland B, Olofsson H, Hesse C, Davidsson P, Minthon L, Jansson A, Palmqvist L, Rymo L.

J Neural Transm. 2000;107(8-9):1065-79.PMID: 11041282 [PubMed - indexed for MEDLINE]Related articles

Putamen mitochondrial energy metabolism is highly correlated to emotional and intellectual impairment in schizophrenics.

Prince JA, Harro J, Blennow K, Gottfries CG, Oreland L.

Neuropsychopharmacology. 2000 Mar;22(3):284-92.PMID: 10693156 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of 167 polymorphisms in 88 genes from candidate neurodegeneration pathways.

Emahazion T, Jobs M, Howell WM, Siegfried M, Wyöni PI, Prince JA, Brookes AJ.

Gene. 1999 Oct 1;238(2):315-24.PMID: 10570959 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial function is differentially altered in the basal ganglia of chronic schizophrenics.

Prince JA, Blennow K, Gottfries CG, Karlsson I, Oreland L.

Neuropsychopharmacology. 1999 Sep;21(3):372-9.PMID: 10457534 [PubMed - indexed for MEDLINE]Related articlesFree article

A cell culture model of cerebral ischemia as a convenient system to screen for neuroprotective drugs.

Ekblom J, Garpenstrand H, Tottmar O, Prince JA, Oreland L.

J Neural Transm Suppl. 1998;52:93-8.PMID: 9564612 [PubMed - indexed for MEDLINE]Related articles

Normalization of cytochrome-c oxidase activity in the rat brain by neuroleptics after chronic treatment with PCP or methamphetamine.

Prince JA, Yassin MS, Oreland L.

Neuropharmacology. 1997 Nov-Dec;36(11-12):1665-78.PMID: 9517438 [PubMed - indexed for MEDLINE]Related articles

A histochemical demonstration of altered cytochrome oxidase activity in the rat brain by neuroleptics.

Prince JA, Yassin MS, Oreland L.

Eur Neuropsychopharmacol. 1998 Feb;8(1):1-6.PMID: 9452933 [PubMed - indexed for MEDLINE]Related articles