PubMed

HDL superphospholipidation enhances key steps in reverse cholesterol transport.

Tchoua U, Gillard BK, Pownall HJ.

Atherosclerosis. 2009 Oct 12. [Epub ahead of print]PMID: 19892352 [PubMed - as supplied by publisher]Related articles

Mechanism of LDL Binding and Release Probed By Structure-Based Mutagenesis of the LDL Receptor.

Huang S, Henry L, Ho YK, Pownall HJ, Rudenko G.

J Lipid Res. 2009 Aug 11. [Epub ahead of print]PMID: 19674976 [PubMed - as supplied by publisher]Related articlesFree article

Apolipoproteins A-I, A-II and E are independently distributed among intracellular and newly secreted HDL of human hepatoma cells.

Gillard BK, Lin HY, Massey JB, Pownall HJ.

Biochim Biophys Acta. 2009 Dec;1791(12):1125-32. Epub 2009 Jul 25.PMID: 19635584 [PubMed - in process]Related articles

Apolipoprotein modulation of streptococcal serum opacity factor activity against human plasma high-density lipoproteins.

Rosales C, Gillard BK, Courtney HS, Blanco-Vaca F, Pownall HJ.

Biochemistry. 2009 Aug 25;48(33):8070-6.PMID: 19618959 [PubMed - indexed for MEDLINE]Related articles

The adipocyte IKK/NFkappaB pathway: a therapeutic target for insulin resistance.

Ruan H, Pownall HJ.

Curr Opin Investig Drugs. 2009 Apr;10(4):346-52. Review.PMID: 19337955 [PubMed - indexed for MEDLINE]Related articles

Disruption of human plasma high-density lipoproteins by streptococcal serum opacity factor requires labile apolipoprotein A-I.

Han M, Gillard BK, Courtney HS, Ward K, Rosales C, Khant H, Ludtke SJ, Pownall HJ.

Biochemistry. 2009 Feb 24;48(7):1481-7.PMID: 19191587 [PubMed - indexed for MEDLINE]Related articles

Mass spectrometric determination of apolipoprotein molecular stoichiometry in reconstituted high density lipoprotein particles.

Massey JB, Pownall HJ, Macha S, Morris J, Tubb MR, Silva RA.

J Lipid Res. 2009 Jun;50(6):1229-36. Epub 2009 Jan 28.PMID: 19179308 [PubMed - indexed for MEDLINE]Related articles

Properties of the products formed by the activity of serum opacity factor against human plasma high-density lipoproteins.

Pownall HJ, Courtney HS, Gillard BK, Massey JB.

Chem Phys Lipids. 2008 Nov;156(1-2):45-51. Epub 2008 Sep 16.PMID: 18838065 [PubMed - indexed for MEDLINE]Related articles

Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions.

Li Y, Choi H, Zhou Z, Nolasco L, Pownall HJ, Voorberg J, Moake JL, Dong JF.

J Thromb Haemost. 2008 Jul;6(7):1135-43. Epub 2008 Jul 1.PMID: 18433456 [PubMed - indexed for MEDLINE]Related articlesFree article

Cholesterol is a determinant of the structures of discoidal high density lipoproteins formed by the solubilization of phospholipid membranes by apolipoprotein A-I.

Massey JB, Pownall HJ.

Biochim Biophys Acta. 2008 May;1781(5):245-53. Epub 2008 Mar 21.PMID: 18406360 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum opacity factor unmasks human plasma high-density lipoprotein instability via selective delipidation and apolipoprotein A-I desorption.

Gillard BK, Courtney HS, Massey JB, Pownall HJ.

Biochemistry. 2007 Nov 13;46(45):12968-78. Epub 2007 Oct 17.PMID: 17941651 [PubMed - indexed for MEDLINE]Related articles

Shear-induced disulfide bond formation regulates adhesion activity of von Willebrand factor.

Choi H, Aboulfatova K, Pownall HJ, Cook R, Dong JF.

J Biol Chem. 2007 Dec 7;282(49):35604-11. Epub 2007 Oct 9.PMID: 17925407 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain uptake and utilization of fatty acids, lipids & lipoproteins: recommendations for future research.

Katz R, Hamilton JA, Pownall HJ, Deckelbaum RJ, Hillard CJ, Leboeuf RC, Watkins PA.

J Mol Neurosci. 2007 Sep;33(1):146-50.PMID: 17901559 [PubMed - indexed for MEDLINE]Related articles

Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study.

Volcik K, Ballantyne CM, Pownall HJ, Sharrett AR, Boerwinkle E.

J Stud Alcohol Drugs. 2007 Jul;68(4):485-92.PMID: 17568951 [PubMed - indexed for MEDLINE]Related articlesFree article

Speciation of human plasma high-density lipoprotein (HDL): HDL stability and apolipoprotein A-I partitioning.

Pownall HJ, Hosken BD, Gillard BK, Higgins CL, Lin HY, Massey JB.

Biochemistry. 2007 Jun 26;46(25):7449-59. Epub 2007 May 27.PMID: 17530866 [PubMed - indexed for MEDLINE]Related articles

Dynamics of dense electronegative low density lipoproteins and their preferential association with lipoprotein phospholipase A(2).

Gaubatz JW, Gillard BK, Massey JB, Hoogeveen RC, Huang M, Lloyd EE, Raya JL, Yang CY, Pownall HJ.

J Lipid Res. 2007 Feb;48(2):348-57. Epub 2006 Nov 13.PMID: 17102149 [PubMed - indexed for MEDLINE]Related articlesFree article

Pro-apoptotic low-density lipoprotein subfractions in type II diabetes.

Yang CY, Chen HH, Huang MT, Raya JL, Yang JH, Chen CH, Gaubatz JW, Pownall HJ, Taylor AA, Ballantyne CM, Jenniskens FA, Smith CV.

Atherosclerosis. 2007 Aug;193(2):283-91. Epub 2006 Oct 9.PMID: 17030034 [PubMed - indexed for MEDLINE]Related articles

Electronegative LDLs from familial hypercholesterolemic patients are physicochemically heterogeneous but uniformly proapoptotic.

Chen HH, Hosken BD, Huang M, Gaubatz JW, Myers CL, Macfarlane RD, Pownall HJ, Yang CY.

J Lipid Res. 2007 Jan;48(1):177-84. Epub 2006 Oct 2.PMID: 17015886 [PubMed - indexed for MEDLINE]Related articlesFree article

Detergent-mediated phospholipidation of plasma lipoproteins increases HDL cholesterophilicity and cholesterol efflux via SR-BI.

Pownall HJ.

Biochemistry. 2006 Sep 26;45(38):11514-22.PMID: 16981711 [PubMed - indexed for MEDLINE]Related articlesFree article

Structures of biologically active oxysterols determine their differential effects on phospholipid membranes.

Massey JB, Pownall HJ.

Biochemistry. 2006 Sep 5;45(35):10747-58.PMID: 16939227 [PubMed - indexed for MEDLINE]Related articles

Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance.

Liao D, Tan H, Hui R, Li Z, Jiang X, Gaubatz J, Yang F, Durante W, Chan L, Schafer AI, Pownall HJ, Yang X, Wang H.

Circ Res. 2006 Sep 15;99(6):598-606. Epub 2006 Aug 24.PMID: 16931800 [PubMed - indexed for MEDLINE]Related articlesFree article

Heart positive: design of a randomized controlled clinical trial of intensive lifestyle intervention, niacin and fenofibrate for HIV lipodystrophy/dyslipidemia.

Samson SL, Pownall HJ, Scott LW, Ballantyne CM, Smith EO, Sekhar RV, Balasubramanyam A.

Contemp Clin Trials. 2006 Dec;27(6):518-30. Epub 2006 Jul 21.PMID: 16914390 [PubMed - indexed for MEDLINE]Related articles

Sustained elevations in NEFA induce cyclooxygenase-2 activity and potentiate THP-1 macrophage foam cell formation.

Lloyd EE, Gaubatz JW, Burns AR, Pownall HJ.

Atherosclerosis. 2007 May;192(1):49-55. Epub 2006 Jul 25.PMID: 16870193 [PubMed - indexed for MEDLINE]Related articles

N-Glycosylation is required for secretion-competent human plasma phospholipid transfer protein.

Qu SJ, Fan HZ, Gillard BK, Pownall HJ.

Protein J. 2006 Feb;25(2):167-73.PMID: 16862459 [PubMed - indexed for MEDLINE]Related articles

The unique role of apolipoprotein A-I in HDL remodeling and metabolism.

Pownall HJ, Ehnholm C.

Curr Opin Lipidol. 2006 Jun;17(3):209-13. Review.PMID: 16680023 [PubMed - indexed for MEDLINE]Related articles

Role of oxysterol structure on the microdomain-induced microsolubilization of phospholipid membranes by apolipoprotein A-I.

Massey JB, Pownall HJ.

Biochemistry. 2005 Nov 1;44(43):14376-84.PMID: 16245954 [PubMed - indexed for MEDLINE]Related articles

Modulation of angiogenic processes in cultured endothelial cells by low density lipoproteins subfractions from patients with familial hypercholesterolemia.

Tai MH, Kuo SM, Liang HT, Chiou KR, Lam HC, Hsu CM, Pownall HJ, Chen HH, Huang MT, Yang CY.

Atherosclerosis. 2006 Jun;186(2):448-57. Epub 2005 Sep 26.PMID: 16185697 [PubMed - indexed for MEDLINE]Related articles

The polar nature of 7-ketocholesterol determines its location within membrane domains and the kinetics of membrane microsolubilization by apolipoprotein A-I.

Massey JB, Pownall HJ.

Biochemistry. 2005 Aug 2;44(30):10423-33.PMID: 16042420 [PubMed - indexed for MEDLINE]Related articles

Remodeling of human plasma lipoproteins by detergent perturbation.

Pownall HJ.

Biochemistry. 2005 Jul 19;44(28):9714-22.PMID: 16008356 [PubMed - indexed for MEDLINE]Related articles

Severely dysregulated disposal of postprandial triacylglycerols exacerbates hypertriacylglycerolemia in HIV lipodystrophy syndrome.

Sekhar RV, Jahoor F, Pownall HJ, Rehman K, Gaubatz J, Iyer D, Balasubramanyam A.

Am J Clin Nutr. 2005 Jun;81(6):1405-10.PMID: 15941894 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhancing reverse cholesterol transport: the case for phosphatidylcholine therapy.

Pownall HJ, Ehnholm C.

Curr Opin Lipidol. 2005 Jun;16(3):265-8. No abstract available. PMID: 15891386 [PubMed - indexed for MEDLINE]Related articles

Plasma factors required for human apolipoprotein A-II dimerization.

Gillard BK, Chen YS, Gaubatz JW, Massey JB, Pownall HJ.

Biochemistry. 2005 Jan 18;44(2):471-9.PMID: 15641771 [PubMed - indexed for MEDLINE]Related articles

Pathophysiology of dyslipidemia and increased cardiovascular risk in HIV lipodystrophy: a model of 'systemic steatosis'.

Balasubramanyam A, Sekhar RV, Jahoor F, Jones PH, Pownall HJ.

Curr Opin Lipidol. 2004 Feb;15(1):59-67. Review.PMID: 15166810 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular implications of HIV-associated dyslipidemic lipodystrophy.

Sekhar RV, Jahoor F, Pownall HJ, Ballantyne CM, Balasubramanyam A.

Curr Atheroscler Rep. 2004 May;6(3):173-9. Review.PMID: 15068741 [PubMed - indexed for MEDLINE]Related articles

Structure of triglyceride-rich human low-density lipoproteins according to cryoelectron microscopy.

Sherman MB, Orlova EV, Decker GL, Chiu W, Pownall HJ.

Biochemistry. 2003 Dec 23;42(50):14988-93.PMID: 14674775 [PubMed - indexed for MEDLINE]Related articles

Energy translocation across cell membranes and membrane models.

Pownall HJ, Hamilton JA.

Acta Physiol Scand. 2003 Aug;178(4):357-65. Review.PMID: 12864740 [PubMed - indexed for MEDLINE]Related articles

Troglitazone antagonizes tumor necrosis factor-alpha-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-kappaB.

Ruan H, Pownall HJ, Lodish HF.

J Biol Chem. 2003 Jul 25;278(30):28181-92. Epub 2003 May 5.PMID: 12732648 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-density lipoprotein in hypercholesterolemic human plasma induces vascular endothelial cell apoptosis by inhibiting fibroblast growth factor 2 transcription.

Chen CH, Jiang T, Yang JH, Jiang W, Lu J, Marathe GK, Pownall HJ, Ballantyne CM, McIntyre TM, Henry PD, Yang CY.

Circulation. 2003 Apr 29;107(16):2102-8. Epub 2003 Apr 14.PMID: 12695302 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural and functional determinants of human plasma phospholipid transfer protein activity as revealed by site-directed mutagenesis of charged amino acids.

Ponsin G, Qu SJ, Fan HZ, Pownall HJ.

Biochemistry. 2003 Apr 22;42(15):4444-51.PMID: 12693940 [PubMed - indexed for MEDLINE]Related articles

Isolation, characterization, and functional assessment of oxidatively modified subfractions of circulating low-density lipoproteins.

Yang CY, Raya JL, Chen HH, Chen CH, Abe Y, Pownall HJ, Taylor AA, Smith CV.

Arterioscler Thromb Vasc Biol. 2003 Jun 1;23(6):1083-90. Epub 2003 Apr 10.PMID: 12689919 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation.

Wang H, Jiang X, Yang F, Gaubatz JW, Ma L, Magera MJ, Yang X, Berger PB, Durante W, Pownall HJ, Schafer AI.

Blood. 2003 May 15;101(10):3901-7. Epub 2002 Dec 27.PMID: 12506016 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients.

Morrisett JD, Abdel-Fattah G, Hoogeveen R, Mitchell E, Ballantyne CM, Pownall HJ, Opekun AR, Jaffe JS, Oppermann S, Kahan BD.

J Lipid Res. 2002 Aug;43(8):1170-80.PMID: 12177161 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic basis of HIV-lipodystrophy syndrome.

Sekhar RV, Jahoor F, White AC, Pownall HJ, Visnegarwala F, Rodriguez-Barradas MC, Sharma M, Reeds PJ, Balasubramanyam A.

Am J Physiol Endocrinol Metab. 2002 Aug;283(2):E332-7.PMID: 12110539 [PubMed - indexed for MEDLINE]Related articlesFree article

Alcohol: lipid metabolism and cardioprotection.

Pownall HJ.

Curr Atheroscler Rep. 2002 Mar;4(2):107-12. Review.PMID: 11822973 [PubMed - indexed for MEDLINE]Related articles

Isolation, quantitation, and characterization of a stable complex formed by Lp[a] binding to triglyceride-rich lipoproteins.

Gaubatz JW, Hoogeveen RC, Hoffman AS, Ghazzaly KG, Pownall HJ, Guevara J Jr, Koschinsky ML, Morrisett JD.

J Lipid Res. 2001 Dec;42(12):2058-68.PMID: 11734579 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of sirolimus on the metabolism of apoB100- containing lipoproteins in renal transplant patients.

Hoogeveen RC, Ballantyne CM, Pownall HJ, Opekun AR, Hachey DL, Jaffe JS, Oppermann S, Kahan BD, Morrisett JD.

Transplantation. 2001 Oct 15;72(7):1244-50.PMID: 11602850 [PubMed - indexed for MEDLINE]Related articles

Cellular transport of nonesterified fatty acids.

Pownall HJ.

J Mol Neurosci. 2001 Apr-Jun;16(2-3):109-15; discussion 151-7. Review.PMID: 11478365 [PubMed - indexed for MEDLINE]Related articles

Effects of high-density lipoprotein(2) on cholesterol transport and acyl-coenzyme A:cholesterol acyltransferase activity in P388D1 macrophages.

Li L, Pownall HJ.

Biochim Biophys Acta. 2001 Jan 15;1530(1):111-22.PMID: 11341963 [PubMed - indexed for MEDLINE]Related articles

Overexpression of 1-acyl-glycerol-3-phosphate acyltransferase-alpha enhances lipid storage in cellular models of adipose tissue and skeletal muscle.

Ruan H, Pownall HJ.

Diabetes. 2001 Feb;50(2):233-40.PMID: 11272131 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of acyl-coenzyme A:cholesterol acyltransferase (ACAT) synthesis, degradation, and translocation by high-density lipoprotein(2) at a low concentration.

Li L, Pownall HJ.

Arterioscler Thromb Vasc Biol. 2000 Dec;20(12):2636-42.PMID: 11116065 [PubMed - indexed for MEDLINE]Related articlesFree article