PubMed

PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression.

Gauthier BR, Wiederkehr A, Baquié M, Dai C, Powers AC, Kerr-Conte J, Pattou F, MacDonald RJ, Ferrer J, Wollheim CB.

Cell Metab. 2009 Aug;10(2):110-8.PMID: 19656489 [PubMed - indexed for MEDLINE]Related articles

Bioluminescence Imaging in Mouse Models Quantifies beta Cell Mass in the Pancreas and After Islet Transplantation.

Virostko J, Radhika A, Poffenberger G, Chen Z, Brissova M, Gilchrist J, Coleman B, Gannon M, Jansen ED, Powers AC.

Mol Imaging Biol. 2009 Jun 23. [Epub ahead of print]PMID: 19548035 [PubMed - as supplied by publisher]Related articles

Molecular imaging of the pancreas in small animal models.

Virostko J, Powers AC.

Gastroenterology. 2009 Feb;136(2):407-9. Epub 2008 Dec 25. Review. No abstract available. PMID: 19105957 [PubMed - indexed for MEDLINE]Related articles

Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets.

Nyman LR, Wells KS, Head WS, McCaughey M, Ford E, Brissova M, Piston DW, Powers AC.

J Clin Invest. 2008 Nov;118(11):3790-7. Epub 2008 Oct 9.PMID: 18846254 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin therapy versus cell-based therapy for type 1 diabetes mellitus: what lies ahead?

Powers AC.

Nat Clin Pract Endocrinol Metab. 2008 Dec;4(12):664-5. Epub 2008 Sep 30. No abstract available. PMID: 18825138 [PubMed - indexed for MEDLINE]Related articles

Revascularization of transplanted islets: can it be improved?

Brissova M, Powers AC.

Diabetes. 2008 Sep;57(9):2269-71. Review. No abstract available. PMID: 18753672 [PubMed - indexed for MEDLINE]Related articlesFree article

Factor XI protein in human pancreas and kidney.

Cheng Q, Kantz J, Poffenberger G, Powers AC, Gailani D.

Thromb Haemost. 2008 Jul;100(1):158-60. No abstract available. PMID: 18612554 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose metabolism in vivo in four commonly used inbred mouse strains.

Berglund ED, Li CY, Poffenberger G, Ayala JE, Fueger PT, Willis SE, Jewell MM, Powers AC, Wasserman DH.

Diabetes. 2008 Jul;57(7):1790-9. Epub 2008 Apr 8.PMID: 18398139 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of luminescent source reconstruction using single-view spectrally resolved bioluminescence images.

Virostko J, Powers AC, Jansen ED.

Appl Opt. 2007 May 1;46(13):2540-7.PMID: 17429468 [PubMed - indexed for MEDLINE]Related articles

Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of beta-cells.

Tweedie E, Artner I, Crawford L, Poffenberger G, Thorens B, Stein R, Powers AC, Gannon M.

Diabetes. 2006 Dec;55(12):3264-70.PMID: 17130469 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function.

Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC.

Diabetes. 2006 Nov;55(11):2974-85.PMID: 17065333 [PubMed - indexed for MEDLINE]Related articlesFree article

Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression.

Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV.

Dev Biol. 2006 Oct 15;298(2):616-31. Epub 2006 Jul 26.PMID: 16962573 [PubMed - indexed for MEDLINE]Related articles

In vivo monitoring of pancreatic beta-cells in a transgenic mouse model.

Smith SJ, Zhang H, Clermont AO, Powers AC, Kaufman DB, Purchio AF, West DB.

Mol Imaging. 2006 Apr-Jun;5(2):65-75.PMID: 16954020 [PubMed - indexed for MEDLINE]Related articles

Polymer scaffolds as synthetic microenvironments for extrahepatic islet transplantation.

Blomeier H, Zhang X, Rives C, Brissova M, Hughes E, Baker M, Powers AC, Kaufman DB, Shea LD, Lowe WL Jr.

Transplantation. 2006 Aug 27;82(4):452-9.PMID: 16926587 [PubMed - indexed for MEDLINE]Related articlesFree article

Current status of imaging pancreatic islets.

Virostko J, Jansen ED, Powers AC.

Curr Diab Rep. 2006 Aug;6(4):328-32.PMID: 16879787 [PubMed - indexed for MEDLINE]Related articles

A novel method of monitoring response to islet transplantation: bioluminescent imaging of an NF-kB transgenic mouse model.

Roth DJ, Jansen ED, Powers AC, Wang TG.

Transplantation. 2006 Apr 27;81(8):1185-90.PMID: 16641606 [PubMed - indexed for MEDLINE]Related articles

Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice.

Wetzel JD, Barton ES, Chappell JD, Baer GS, Mochow-Grundy M, Rodgers SE, Shyr Y, Powers AC, Thomas JW, Dermody TS.

J Virol. 2006 Mar;80(6):3078-82.PMID: 16501117 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation of islet-like hormone-producing cells in vitro from adult human pancreas.

Atouf F, Choi Y, Fowler MJ, Poffenberger G, Vobecky J, Ta M, Chapman GB, Powers AC, Lumelsky NL.

Cell Transplant. 2005;14(10):735-48.PMID: 16454348 [PubMed - indexed for MEDLINE]Related articles

Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo?

Nunemaker CS, Zhang M, Wasserman DH, McGuinness OP, Powers AC, Bertram R, Sherman A, Satin LS.

Diabetes. 2005 Dec;54(12):3517-22.PMID: 16306370 [PubMed - indexed for MEDLINE]Related articlesFree article

Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene.

Park SY, Wang X, Chen Z, Powers AC, Magnuson MA, Head WS, Piston DW, Bell GI.

Genesis. 2005 Oct;43(2):80-6.PMID: 16108006 [PubMed - indexed for MEDLINE]Related articles

Proteomic exploration of pancreatic islets in mice null for the alpha2A adrenergic receptor.

Hu X, Friedman D, Hill S, Caprioli R, Nicholson W, Powers AC, Hunter L, Limbird LE.

J Mol Endocrinol. 2005 Aug;35(1):73-88.PMID: 16087723 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy.

Brissova M, Fowler MJ, Nicholson WE, Chu A, Hirshberg B, Harlan DM, Powers AC.

J Histochem Cytochem. 2005 Sep;53(9):1087-97. Epub 2005 May 27.PMID: 15923354 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging.

Fowler M, Virostko J, Chen Z, Poffenberger G, Radhika A, Brissova M, Shiota M, Nicholson WE, Shi Y, Hirshberg B, Harlan DM, Jansen ED, Powers AC.

Transplantation. 2005 Apr 15;79(7):768-76.PMID: 15818318 [PubMed - indexed for MEDLINE]Related articles

Factors influencing quantification of in vivo bioluminescence imaging: application to assessment of pancreatic islet transplants.

Virostko J, Chen Z, Fowler M, Poffenberger G, Powers AC, Jansen ED.

Mol Imaging. 2004 Oct;3(4):333-42.PMID: 15802050 [PubMed - indexed for MEDLINE]Related articles

Diabetes referrals at a Veterans Administration tertiary facility: who are the patients and why are they referred?

Nguyen CV, Powers AC, Greenspan DL, Elasy TA.

Diabetes Care. 2005 Feb;28(2):423-4. No abstract available. PMID: 15677805 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis.

Brissova M, Blaha M, Spear C, Nicholson W, Radhika A, Shiota M, Charron MJ, Wright CV, Powers AC.

Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E707-14. Epub 2004 Nov 23.PMID: 15562255 [PubMed - indexed for MEDLINE]Related articlesFree article

Ascorbic acid recycling by cultured beta cells: effects of increased glucose metabolism.

Steffner RJ, Wu L, Powers AC, May JM.

Free Radic Biol Med. 2004 Nov 15;37(10):1612-21.PMID: 15477012 [PubMed - indexed for MEDLINE]Related articles

Compartmentalization of transport and phosphorylation of glucose in a hepatoma cell line.

Whitesell RR, Ardehali H, Beechem JM, Powers AC, Van der Meer W, Perriott LM, Granner DK.

Biochem J. 2005 Mar 1;386(Pt 2):245-53.PMID: 15473866 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets.

Brissova M, Fowler M, Wiebe P, Shostak A, Shiota M, Radhika A, Lin PC, Gannon M, Powers AC.

Diabetes. 2004 May;53(5):1318-25.PMID: 15111502 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines.

Wu L, Nicholson W, Knobel SM, Steffner RJ, May JM, Piston DW, Powers AC.

J Biol Chem. 2004 Mar 26;279(13):12126-34. Epub 2003 Dec 19.PMID: 14688272 [PubMed - indexed for MEDLINE]Related articlesFree article

A fall in portal vein insulin does not cause the alpha-cell response to mild, non-insulin-induced hypoglycemia in conscious dogs.

Gustavson SM, Nishizawa M, Farmer B, Neal D, Brissova M, Powers AC, Cherrington AD.

Metabolism. 2003 Nov;52(11):1418-25.PMID: 14624400 [PubMed - indexed for MEDLINE]Related articles

Engineering physiologically regulated insulin secretion in non-beta cells by expressing glucagon-like peptide 1 receptor.

Wu L, Nicholson W, Wu CY, Xu M, McGaha A, Shiota M, Powers AC.

Gene Ther. 2003 Sep;10(19):1712-20.PMID: 12923570 [PubMed - indexed for MEDLINE]Related articles

Impact of medical student research in the development of physician-scientists.

Solomon SS, Tom SC, Pichert J, Wasserman D, Powers AC.

J Investig Med. 2003 May;51(3):149-56.PMID: 12769197 [PubMed - indexed for MEDLINE]Related articles

Assessment of insulin secretion in the mouse.

Brissova M, Nicholson WE, Shiota M, Powers AC.

Methods Mol Med. 2003;83:23-45. No abstract available. PMID: 12619713 [PubMed - indexed for MEDLINE]Related articles

Pancreatic islet beta-cells transiently metabolize pyruvate.

Rocheleau JV, Head WS, Nicholson WE, Powers AC, Piston DW.

J Biol Chem. 2002 Aug 23;277(34):30914-20. Epub 2002 Jun 17.PMID: 12070148 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion.

Brissova M, Shiota M, Nicholson WE, Gannon M, Knobel SM, Piston DW, Wright CV, Powers AC.

J Biol Chem. 2002 Mar 29;277(13):11225-32. Epub 2002 Jan 7.PMID: 11781323 [PubMed - indexed for MEDLINE]Related articlesFree article

Practical management of diabetes in critically ill patients.

Boord JB, Graber AL, Christman JW, Powers AC.

Am J Respir Crit Care Med. 2001 Nov 15;164(10 Pt 1):1763-7. Review. No abstract available. PMID: 11734423 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose uptake and metabolism by cultured human skeletal muscle cells: rate-limiting steps.

Perriott LM, Kono T, Whitesell RR, Knobel SM, Piston DW, Granner DK, Powers AC, May JM.

Am J Physiol Endocrinol Metab. 2001 Jul;281(1):E72-80.PMID: 11404224 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative analysis of epitope recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different autoimmune disorders.

Powers AC, Bavik K, Tremble J, Daw K, Scherbaum WA, Banga JP.

Clin Exp Immunol. 1999 Dec;118(3):349-56.PMID: 10594551 [PubMed - indexed for MEDLINE]Related articlesFree article

Different functional domains of GLUT2 glucose transporter are required for glucose affinity and substrate specificity.

Wu L, Fritz JD, Powers AC.

Endocrinology. 1998 Oct;139(10):4205-12.PMID: 9751501 [PubMed - indexed for MEDLINE]Related articlesFree article

Permeability assessment of capsules for islet transplantation.

Powers AC, Brissová M, Lacík I, Anilkumar AV, Shahrokhi K, Wang TG.

Ann N Y Acad Sci. 1997 Dec 31;831:208-16.PMID: 9616712 [PubMed - indexed for MEDLINE]Related articles

Control and measurement of permeability for design of microcapsule cell delivery system.

Brissová M, Lacík I, Powers AC, Anilkumar AV, Wang T.

J Biomed Mater Res. 1998 Jan;39(1):61-70.PMID: 9429097 [PubMed - indexed for MEDLINE]Related articles

New capsule with tailored properties for the encapsulation of living cells.

Lacík I, Brissová M, Anilkumar AV, Powers AC, Wang T.

J Biomed Mater Res. 1998 Jan;39(1):52-60.PMID: 9429096 [PubMed - indexed for MEDLINE]Related articles

Human B cells secreting immunoglobulin G to glutamic acid decarboxylase-65 from a nondiabetic patient with multiple autoantibodies and Graves' disease: a comparison with those present in type 1 diabetes.

Tremble J, Morgenthaler NG, Vlug A, Powers AC, Christie MR, Scherbaum WA, Banga JP.

J Clin Endocrinol Metab. 1997 Aug;82(8):2664-70.PMID: 9253351 [PubMed - indexed for MEDLINE]Related articlesFree article

An encapsulation system for the immunoisolation of pancreatic islets.

Wang T, Lacík I, Brissová M, Anilkumar AV, Prokop A, Hunkeler D, Green R, Shahrokhi K, Powers AC.

Nat Biotechnol. 1997 Apr;15(4):358-62.PMID: 9094138 [PubMed - indexed for MEDLINE]Related articles

Gene-based neurotransmitter modulation in cerebellar granule neurons.

Fritz JD, Utz AL, Hale NM, Wu L, Powers AC, Verdoorn TA, Robertson D.

J Neurochem. 1997 Jan;68(1):204-12.PMID: 8978727 [PubMed - indexed for MEDLINE]Related articles

Evaluation of microcapsule permeability via inverse size exclusion chromatography.

Brissová M, Petro M, Lacík I, Powers AC, Wang T.

Anal Biochem. 1996 Nov 1;242(1):104-11.PMID: 8923972 [PubMed - indexed for MEDLINE]Related articles

Glucose transport activity and ligand binding (cytochalasin B, IAPS-forskolin) of chimeric constructs of GLUT2 and GLUT4 expressed in COS-7-cells.

Wandel S, Buchs A, Schürmann A, Summers SA, Powers AC, Shanahan MF, Joost HG.

Biochim Biophys Acta. 1996 Oct 2;1284(1):56-62.PMID: 8865815 [PubMed - indexed for MEDLINE]Related articles

Murine monoclonal glutamic acid decarboxylase (GAD)65 antibodies recognize autoimmune-associated GAD epitope regions targeted in patients with type 1 diabetes mellitus and stiff-man syndrome.

Ziegler B, Schlosser M, Lühder F, Strebelow M, Augstein P, Northemann W, Powers AC, Ziegler M.

Acta Diabetol. 1996 Sep;33(3):225-31.PMID: 8904930 [PubMed - indexed for MEDLINE]Related articles

Prediabetic markers in children with stress hyperglycemia.

Bhisitkul DM, Vinik AI, Morrow AL, She JX, Shults J, Powers AC, Maclaren NK.

Arch Pediatr Adolesc Med. 1996 Sep;150(9):936-41.PMID: 8790124 [PubMed - indexed for MEDLINE]Related articles