PubMed

Genetic Effects on Postprandial Variations of Inflammatory Markers in Healthy Individuals.

Cheng YC, Kao WH, Mitchell BD, Sharrett AR, Ryan KA, Vogel RA, Shuldiner AR, Pollin TI.

Obesity (Silver Spring). 2009 Nov 12. [Epub ahead of print]PMID: 19910936 [PubMed - as supplied by publisher]Related articles

National Institutes of Health State-of-the-Science Conference Statement: Family History and Improving Health.

Berg AO, Baird MA, Botkin JR, Driscoll DA, Fishman PA, Guarino PD, Hiatt RA, Jarvik GP, Millon-Underwood S, Morgan TM, Mulvihill JJ, Pollin TI, Schimmel SR, Stefanek ME, Vollmer WM, Williams JK.

Ann Intern Med. 2009 Nov 2. [Epub ahead of print] No abstract available. PMID: 19884615 [PubMed - as supplied by publisher]Related articlesFree article

NIH State-of-the-Science Conference Statement: Family History and Improving Health.

Baird MA, Berg AO, Botkin JR, Driscoll DA, Fishman PA, Guarino PD, Hiatt RA, Jarvik GP, Millon-Underwood S, Morgan TM, Mulvihill JJ, Pollin TI, Schimmel SR, Stefanek ME, Vollmer WM, Williams JK.

NIH Consens State Sci Statements. 2009 Aug 26;26(1). [Epub ahead of print]PMID: 19721470 [PubMed - as supplied by publisher]Related articlesFree article

Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.

Shuldiner AR, O'Connell JR, Bliden KP, Gandhi A, Ryan K, Horenstein RB, Damcott CM, Pakyz R, Tantry US, Gibson Q, Pollin TI, Post W, Parsa A, Mitchell BD, Faraday N, Herzog W, Gurbel PA.

JAMA. 2009 Aug 26;302(8):849-57.PMID: 19706858 [PubMed - indexed for MEDLINE]Related articles

Glucokinase regulatory protein gene polymorphism affects postprandial lipemic response in a dietary intervention study.

Shen H, Pollin TI, Damcott CM, McLenithan JC, Mitchell BD, Shuldiner AR.

Hum Genet. 2009 Oct;126(4):567-74. Epub 2009 Jun 13.PMID: 19526250 [PubMed - indexed for MEDLINE]Related articles

Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study.

Ling H, Waterworth DM, Stirnadel HA, Pollin TI, Barter PJ, Kesäniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Cohen JC, Grundy SM, Mooser VE, Mitchell BD.

Obesity (Silver Spring). 2009 Apr;17(4):737-44. Epub 2009 Jan 22.PMID: 19165155 [PubMed - indexed for MEDLINE]Related articles

Scavenger receptor class B type I protein as an independent predictor of high-density lipoprotein cholesterol levels in subjects with hyperalphalipoproteinemia.

West M, Greason E, Kolmakova A, Jahangiri A, Asztalos B, Pollin TI, Rodriguez A.

J Clin Endocrinol Metab. 2009 Apr;94(4):1451-7. Epub 2009 Jan 21.PMID: 19158204 [PubMed - indexed for MEDLINE]Related articles

A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection.

Pollin TI, Damcott CM, Shen H, Ott SH, Shelton J, Horenstein RB, Post W, McLenithan JC, Bielak LF, Peyser PA, Mitchell BD, Miller M, O'Connell JR, Shuldiner AR.

Science. 2008 Dec 12;322(5908):1702-5.PMID: 19074352 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigating parent of origin effects in studies of type 2 diabetes and obesity.

Rampersaud E, Mitchell BD, Naj AC, Pollin TI.

Curr Diabetes Rev. 2008 Nov;4(4):329-39. Review.PMID: 18991601 [PubMed - indexed for MEDLINE]Related articles

Physical activity and the association of common FTO gene variants with body mass index and obesity.

Rampersaud E, Mitchell BD, Pollin TI, Fu M, Shen H, O'Connell JR, Ducharme JL, Hines S, Sack P, Naglieri R, Shuldiner AR, Snitker S.

Arch Intern Med. 2008 Sep 8;168(16):1791-7. Erratum in: Arch Intern Med. 2009 Mar 9;169(5):453. PMID: 18779467 [PubMed - indexed for MEDLINE]Related articlesFree article

Osteoporosis-pseudoglioma syndrome: description of 9 new cases and beneficial response to bisphosphonates.

Streeten EA, McBride D, Puffenberger E, Hoffman ME, Pollin TI, Donnelly P, Sack P, Morton H.

Bone. 2008 Sep;43(3):584-90. Epub 2008 May 7.PMID: 18602879 [PubMed - indexed for MEDLINE]Related articles

Autosome-wide linkage analysis of hip structural phenotypes in the Old Order Amish.

Streeten EA, Beck TJ, O'Connell JR, Rampersand E, McBride DJ, Takala SL, Pollin TI, Uusi-Rasi K, Mitchell BD, Shuldiner AR.

Bone. 2008 Sep;43(3):607-12. Epub 2008 Apr 25.PMID: 18555766 [PubMed - indexed for MEDLINE]Related articlesFree article

Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.

Moore AF, Jablonski KA, McAteer JB, Saxena R, Pollin TI, Franks PW, Hanson RL, Shuldiner AR, Knowler WC, Altshuler D, Florez JC; Diabetes Prevention Program Research Group.

Diabetes. 2008 Sep;57(9):2503-10. Epub 2008 Jun 10.PMID: 18544707 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin levels and genotype: a potential regulator of life span in humans.

Atzmon G, Pollin TI, Crandall J, Tanner K, Schechter CB, Scherer PE, Rincon M, Siegel G, Katz M, Lipton RB, Shuldiner AR, Barzilai N.

J Gerontol A Biol Sci Med Sci. 2008 May;63(5):447-53.PMID: 18511746 [PubMed - indexed for MEDLINE]Related articles

The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study.

Mitchell BD, McArdle PF, Shen H, Rampersaud E, Pollin TI, Bielak LF, Jaquish C, Douglas JA, Roy-Gagnon MH, Sack P, Naglieri R, Hines S, Horenstein RB, Chang YP, Post W, Ryan KA, Brereton NH, Pakyz RE, Sorkin J, Damcott CM, O'Connell JR, Mangano C, Corretti M, Vogel R, Herzog W, Weir MR, Peyser PA, Shuldiner AR.

Am Heart J. 2008 May;155(5):823-8. Epub 2008 Mar 5.PMID: 18440328 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigations of the Y chromosome, male founder structure and YSTR mutation rates in the Old Order Amish.

Pollin TI, McBride DJ, Agarwala R, Schäffer AA, Shuldiner AR, Mitchell BD, O'Connell JR.

Hum Hered. 2008;65(2):91-104. Epub 2007 Sep 26.PMID: 17898540 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of TLR4 polymorphisms with symptomatic respiratory syncytial virus infection in high-risk infants and young children.

Awomoyi AA, Rallabhandi P, Pollin TI, Lorenz E, Sztein MB, Boukhvalova MS, Hemming VG, Blanco JC, Vogel SN.

J Immunol. 2007 Sep 1;179(5):3171-7.PMID: 17709532 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide linkage scan of insulin level derived traits: the Amish Family Diabetes Study.

Hsueh WC, Silver KD, Pollin TI, Bell CJ, O'Connell JR, Mitchell BD, Shuldiner AR.

Diabetes. 2007 Oct;56(10):2643-8. Epub 2007 Jul 23.PMID: 17646211 [PubMed - indexed for MEDLINE]Related articlesFree article

Accounting for relatedness in family based genetic association studies.

McArdle PF, O'Connell JR, Pollin TI, Baumgarten M, Shuldiner AR, Peyser PA, Mitchell BD.

Hum Hered. 2007;64(4):234-42. Epub 2007 Jun 14.PMID: 17570925 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that Rho guanine nucleotide exchange factor 11 (ARHGEF11) on 1q21 is a type 2 diabetes susceptibility gene in the Old Order Amish.

Fu M, Sabra MM, Damcott C, Pollin TI, Ma L, Ott S, Shelton JC, Shi X, Reinhart L, O'Connell J, Mitchell BD, Baier LJ, Shuldiner AR.

Diabetes. 2007 May;56(5):1363-8. Epub 2007 Mar 16.PMID: 17369523 [PubMed - indexed for MEDLINE]Related articlesFree article

Omentin plasma levels and gene expression are decreased in obesity.

de Souza Batista CM, Yang RZ, Lee MJ, Glynn NM, Yu DZ, Pray J, Ndubuizu K, Patil S, Schwartz A, Kligman M, Fried SK, Gong DW, Shuldiner AR, Pollin TI, McLenithan JC.

Diabetes. 2007 Jun;56(6):1655-61. Epub 2007 Feb 28.PMID: 17329619 [PubMed - indexed for MEDLINE]Related articlesFree article

Meta-analysis of genome-wide linkage studies of quantitative lipid traits in families ascertained for type 2 diabetes.

Malhotra A, Elbein SC, Ng MC, Duggirala R, Arya R, Imperatore G, Adeyemo A, Pollin TI, Hsueh WC, Chan JC, Rotimi C, Hanson RL, Hasstedt SJ, Wolford JK.

Diabetes. 2007 Mar;56(3):890-6.PMID: 17327462 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait loci for BMD identified by autosome-wide linkage scan to chromosomes 7q and 21q in men from the Amish Family Osteoporosis Study.

Streeten EA, McBride DJ, Pollin TI, Ryan K, Shapiro J, Ott S, Mitchell BD, Shuldiner AR, O'Connell JR.

J Bone Miner Res. 2006 Sep;21(9):1433-42.PMID: 16939402 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.

Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, Mitchell BD, Shuldiner AR.

Diabetes. 2006 Sep;55(9):2654-9.PMID: 16936218 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.

Zeggini E, Damcott CM, Hanson RL, Karim MA, Rayner NW, Groves CJ, Baier LJ, Hale TC, Hattersley AT, Hitman GA, Hunt SE, Knowler WC, Mitchell BD, Ng MC, O'Connell JR, Pollin TI, Vaxillaire M, Walker M, Wang X, Whittaker P, Xiang K, Jia W, Chan JC, Froguel P, Deloukas P, Shuldiner AR, Elbein SC, McCarthy MI; International Type 2 Diabetes 1q Consortium.

Diabetes. 2006 Sep;55(9):2541-8. Erratum in: Diabetes. 2006 Nov;55(11):3197. Kunsun, Xiang [corrected to Xiang, Kunsan]. PMID: 16936202 [PubMed - indexed for MEDLINE]Related articlesFree article

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program.

Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, Knowler WC, Nathan DM, Altshuler D; Diabetes Prevention Program Research Group.

N Engl J Med. 2006 Jul 20;355(3):241-50.PMID: 16855264 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications.

Yang RZ, Lee MJ, Hu H, Pollin TI, Ryan AS, Nicklas BJ, Snitker S, Horenstein RB, Hull K, Goldberg NH, Goldberg AP, Shuldiner AR, Fried SK, Gong DW.

PLoS Med. 2006 Jun;3(6):e287.PMID: 16737350 [PubMed - indexed for MEDLINE]Related articlesFree article

Does having children extend life span? A genealogical study of parity and longevity in the Amish.

McArdle PF, Pollin TI, O'Connell JR, Sorkin JD, Agarwala R, Schäffer AA, Streeten EA, King TM, Shuldiner AR, Mitchell BD.

J Gerontol A Biol Sci Med Sci. 2006 Feb;61(2):190-5.PMID: 16510865 [PubMed - indexed for MEDLINE]Related articles

Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish.

Steinle NI, Pollin TI, O'Connell JR, Mitchell BD, Shuldiner AR.

J Clin Endocrinol Metab. 2005 Dec;90(12):6672-7. Epub 2005 Oct 4.PMID: 16204371 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish.

Damcott CM, Ott SH, Pollin TI, Reinhart LJ, Wang J, O'connell JR, Mitchell BD, Shuldiner AR.

Diabetes. 2005 Jul;54(7):2245-50.PMID: 15983228 [PubMed - indexed for MEDLINE]Related articlesFree article

The relationship between parity and bone mineral density in women characterized by a homogeneous lifestyle and high parity.

Streeten EA, Ryan KA, McBride DJ, Pollin TI, Shuldiner AR, Mitchell BD.

J Clin Endocrinol Metab. 2005 Aug;90(8):4536-41. Epub 2005 May 17.PMID: 15899951 [PubMed - indexed for MEDLINE]Related articlesFree article

The exon 1 Cys7Gly polymorphism within the betacellulin gene is associated with type 2 diabetes in African Americans.

Silver K, Tolea M, Wang J, Pollin TI, Yao F, Mitchell BD.

Diabetes. 2005 Apr;54(4):1179-84.PMID: 15793259 [PubMed - indexed for MEDLINE]Related articlesFree article

Exploring the genetics of longevity in the Old Order Amish.

Sorkin J, Post W, Pollin TI, O'Connell JR, Mitchell BD, Shuldiner AR.

Mech Ageing Dev. 2005 Feb;126(2):347-50.PMID: 15621217 [PubMed - indexed for MEDLINE]Related articles

Linkage of plasma adiponectin levels to 3q27 explained by association with variation in the APM1 gene.

Pollin TI, Tanner K, O'connell JR, Ott SH, Damcott CM, Shuldiner AR, McLenithan JC, Mitchell BD.

Diabetes. 2005 Jan;54(1):268-74.PMID: 15616038 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in both promoters of hepatocyte nuclear factor 4-alpha are associated with type 2 diabetes in the Amish.

Damcott CM, Hoppman N, Ott SH, Reinhart LJ, Wang J, Pollin TI, O'Connell JR, Mitchell BD, Shuldiner AR.

Diabetes. 2004 Dec;53(12):3337-41.PMID: 15561969 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphism in the calsequestrin 1 (CASQ1) gene on chromosome 1q21 is associated with type 2 diabetes in the old order Amish.

Fu M, Damcott CM, Sabra M, Pollin TI, Ott SH, Wang J, Garant MJ, O'Connell JR, Mitchell BD, Shuldiner AR.

Diabetes. 2004 Dec;53(12):3292-9.PMID: 15561962 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in the lamin A/C gene: associations with metabolic syndrome.

Steinle NI, Kazlauskaite R, Imumorin IG, Hsueh WC, Pollin TI, O'Connell JR, Mitchell BD, Shuldiner AR.

Arterioscler Thromb Vasc Biol. 2004 Sep;24(9):1708-13. Epub 2004 Jun 17.PMID: 15205219 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide scan of serum lipid levels in the Old Order Amish.

Pollin TI, Hsueh WC, Steinle NI, Snitker S, Shuldiner AR, Mitchell BD.

Atherosclerosis. 2004 Mar;173(1):89-96.PMID: 15177127 [PubMed - indexed for MEDLINE]Related articles

Hepatic lipase genotype, diabetes risk, and implications for preventative medicine.

Shuldiner AR, Hoppman N, Pollin TI.

J Clin Endocrinol Metab. 2004 May;89(5):2015-8. Review. No abstract available. PMID: 15126513 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced incidence of hip fracture in the Old Order Amish.

Streeten EA, McBride DJ, Lodge AL, Pollin TI, Stinchcomb DG, Agarwala R, Schäffer AA, Shapiro JR, Shuldiner AR, Mitchell BD.

J Bone Miner Res. 2004 Feb;19(2):308-13. Epub 2003 Dec 16.PMID: 14969401 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies in Type 1 and Type 2 diabetes in the Old Order Amish of Lancaster County, Pennsylvania.

Miura J, Pollin TI, Hu Y, Harashima SI, Notkins AL, Shuldiner AR.

Diabetologia. 2003 Jul;46(7):1024-5. Epub 2003 Jun 18. No abstract available. PMID: 12819905 [PubMed - indexed for MEDLINE]Related articles

A genome-wide scan for autoimmune thyroiditis in the Old Order Amish: replication of genetic linkage on chromosome 5q11.2-q14.3.

Allen EM, Hsueh WC, Sabra MM, Pollin TI, Ladenson PW, Silver KD, Mitchell BD, Shuldiner AR.

J Clin Endocrinol Metab. 2003 Mar;88(3):1292-6.PMID: 12629121 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24.

Hsueh WC, St Jean PL, Mitchell BD, Pollin TI, Knowler WC, Ehm MG, Bell CJ, Sakul H, Wagner MJ, Burns DK, Shuldiner AR.

Diabetes. 2003 Feb;52(2):550-7.PMID: 12540634 [PubMed - indexed for MEDLINE]Related articlesFree article

Eating behavior in the Old Order Amish: heritability analysis and a genome-wide linkage analysis.

Steinle NI, Hsueh WC, Snitker S, Pollin TI, Sakul H, St Jean PL, Bell CJ, Mitchell BD, Shuldiner AR.

Am J Clin Nutr. 2002 Jun;75(6):1098-106.PMID: 12036819 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between obesity and a polymorphism in the beta(1)-adrenoceptor gene (Gly389Arg ADRB1) in Caucasian women.

Dionne IJ, Garant MJ, Nolan AA, Pollin TI, Lewis DG, Shuldiner AR, Poehlman ET.

Int J Obes Relat Metab Disord. 2002 May;26(5):633-9.PMID: 12032746 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor.

Mentuccia D, Proietti-Pannunzi L, Tanner K, Bacci V, Pollin TI, Poehlman ET, Shuldiner AR, Celi FS.

Diabetes. 2002 Mar;51(3):880-3.PMID: 11872697 [PubMed - indexed for MEDLINE]Related articlesFree article

Heritability of life span in the Old Order Amish.

Mitchell BD, Hsueh WC, King TM, Pollin TI, Sorkin J, Agarwala R, Schäffer AA, Shuldiner AR.

Am J Med Genet. 2001 Sep 1;102(4):346-52.PMID: 11503162 [PubMed - indexed for MEDLINE]Related articles

Genome-wide scan of obesity in the Old Order Amish.

Hsueh WC, Mitchell BD, Schneider JL, St Jean PL, Pollin TI, Ehm MG, Wagner MJ, Burns DK, Sakul H, Bell CJ, Shuldiner AR.

J Clin Endocrinol Metab. 2001 Mar;86(3):1199-205.PMID: 11238509 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of an interactive effect of beta3- and alpha2b-adrenoceptor gene polymorphisms on fat mass in Caucasian women.

Dionne IJ, Turner AN, Tchernof A, Pollin TI, Avrithi D, Gray D, Shuldiner AR, Poehlman ET.

Diabetes. 2001 Jan;50(1):91-5.PMID: 11147800 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk of abnormal pregnancy outcome in carriers of balanced reciprocal translocations involving the Miller-Dieker syndrome (MDS) critical region in chromosome 17p13.3.

Pollin TI, Dobyns WB, Crowe CA, Ledbetter DH, Bailey-Wilson JE, Smith AC.

Am J Med Genet. 1999 Aug 6;85(4):369-75.PMID: 10398263 [PubMed - indexed for MEDLINE]Related articles