PubMed

Role of seminiferous tubular development in determining the FSH versus LH responsiveness to GnRH in early sexual maturation.

Pitteloud N, Thambundit A, Dwyer AA, Falardeau JL, Plummer L, Caronia LM, Hayes FJ, Lee H, Boepple PA, Crowley WF Jr.

Neuroendocrinology. 2009;90(3):260-8. Epub 2009 Oct 15.PMID: 19829004 [PubMed - in process]Related articles

Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism.

Raivio T, Sidis Y, Plummer L, Chen H, Ma J, Mukherjee A, Jacobson-Dickman E, Quinton R, Van Vliet G, Lavoie H, Hughes VA, Dwyer A, Hayes FJ, Xu S, Sparks S, Kaiser UB, Mohammadi M, Pitteloud N.

J Clin Endocrinol Metab. 2009 Nov;94(11):4380-90. Epub 2009 Oct 9.PMID: 19820032 [PubMed - in process]Related articles

GNRH1 mutations in patients with idiopathic hypogonadotropic hypogonadism.

Chan YM, de Guillebon A, Lang-Muritano M, Plummer L, Cerrato F, Tsiaras S, Gaspert A, Lavoie HB, Wu CH, Crowley WF Jr, Amory JK, Pitteloud N, Seminara SB.

Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11703-8. Epub 2009 Jun 30.PMID: 19567835 [PubMed - indexed for MEDLINE]Related articles

A crystallographic snapshot of tyrosine trans-phosphorylation in action.

Chen H, Xu CF, Ma J, Eliseenkova AV, Li W, Pollock PM, Pitteloud N, Miller WT, Neubert TA, Mohammadi M.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19660-5. Epub 2008 Dec 5.PMID: 19060208 [PubMed - indexed for MEDLINE]Related articlesFree article

CHD7 mutations in patients initially diagnosed with Kallmann syndrome--the clinical overlap with CHARGE syndrome.

Jongmans MC, van Ravenswaaij-Arts CM, Pitteloud N, Ogata T, Sato N, Claahsen-van der Grinten HL, van der Donk K, Seminara S, Bergman JE, Brunner HG, Crowley WF Jr, Hoefsloot LH.

Clin Genet. 2009 Jan;75(1):65-71. Epub 2008 Nov 17.PMID: 19021638 [PubMed - indexed for MEDLINE]Related articles

Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice.

Falardeau J, Chung WC, Beenken A, Raivio T, Plummer L, Sidis Y, Jacobson-Dickman EE, Eliseenkova AV, Ma J, Dwyer A, Quinton R, Na S, Hall JE, Huot C, Alois N, Pearce SH, Cole LW, Hughes V, Mohammadi M, Tsai P, Pitteloud N.

J Clin Invest. 2008 Aug;118(8):2822-31.PMID: 18596921 [PubMed - indexed for MEDLINE]Related articlesFree article

New genes controlling human reproduction and how you find them.

Crowley WF Jr, Pitteloud N, Seminara S.

Trans Am Clin Climatol Assoc. 2008;119:29-37; discussion 37-8. Review.PMID: 18596868 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations in prokineticin 2 and prokineticin receptor 2 genes in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum.

Cole LW, Sidis Y, Zhang C, Quinton R, Plummer L, Pignatelli D, Hughes VA, Dwyer AA, Raivio T, Hayes FJ, Seminara SB, Huot C, Alos N, Speiser P, Takeshita A, Van Vliet G, Pearce S, Crowley WF Jr, Zhou QY, Pitteloud N.

J Clin Endocrinol Metab. 2008 Sep;93(9):3551-9. Epub 2008 Jun 17.PMID: 18559922 [PubMed - indexed for MEDLINE]Related articlesFree article

The relative role of gonadal sex steroids and gonadotropin-releasing hormone pulse frequency in the regulation of follicle-stimulating hormone secretion in men.

Pitteloud N, Dwyer AA, DeCruz S, Lee H, Boepple PA, Crowley WF Jr, Hayes FJ.

J Clin Endocrinol Metab. 2008 Jul;93(7):2686-92. Epub 2008 Apr 29.PMID: 18445673 [PubMed - indexed for MEDLINE]Related articlesFree article

Relative roles of inhibin B and sex steroids in the negative feedback regulation of follicle-stimulating hormone in men across the full spectrum of seminiferous epithelium function.

Boepple PA, Hayes FJ, Dwyer AA, Raivio T, Lee H, Crowley WF Jr, Pitteloud N.

J Clin Endocrinol Metab. 2008 May;93(5):1809-14. Epub 2008 Feb 12.PMID: 18270253 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of luteinizing hormone secretion by testosterone in men requires aromatization for its pituitary but not its hypothalamic effects: evidence from the tandem study of normal and gonadotropin-releasing hormone-deficient men.

Pitteloud N, Dwyer AA, DeCruz S, Lee H, Boepple PA, Crowley WF Jr, Hayes FJ.

J Clin Endocrinol Metab. 2008 Mar;93(3):784-91. Epub 2007 Dec 11.PMID: 18073301 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism.

Pitteloud N, Zhang C, Pignatelli D, Li JD, Raivio T, Cole LW, Plummer L, Jacobson-Dickman EE, Mellon PL, Zhou QY, Crowley WF Jr.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17447-52. Epub 2007 Oct 24.PMID: 17959774 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of idiopathic hypogonadotropic hypogonadism.

Raivio T, Falardeau J, Dwyer A, Quinton R, Hayes FJ, Hughes VA, Cole LW, Pearce SH, Lee H, Boepple P, Crowley WF Jr, Pitteloud N.

N Engl J Med. 2007 Aug 30;357(9):863-73.PMID: 17761590 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism.

Yialamas MA, Dwyer AA, Hanley E, Lee H, Pitteloud N, Hayes FJ.

J Clin Endocrinol Metab. 2007 Nov;92(11):4254-9. Epub 2007 Aug 28.PMID: 17726076 [PubMed - indexed for MEDLINE]Related articlesFree article

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism.

Pitteloud N, Quinton R, Pearce S, Raivio T, Acierno J, Dwyer A, Plummer L, Hughes V, Seminara S, Cheng YZ, Li WP, Maccoll G, Eliseenkova AV, Olsen SK, Ibrahimi OA, Hayes FJ, Boepple P, Hall JE, Bouloux P, Mohammadi M, Crowley W.

J Clin Invest. 2007 Feb;117(2):457-63. Epub 2007 Jan 18.PMID: 17235395 [PubMed - indexed for MEDLINE]Related articlesFree article

Coding sequence analysis of GNRHR and GPR54 in patients with congenital and adult-onset forms of hypogonadotropic hypogonadism.

Cerrato F, Shagoury J, Kralickova M, Dwyer A, Falardeau J, Ozata M, Van Vliet G, Bouloux P, Hall JE, Hayes FJ, Pitteloud N, Martin KA, Welt C, Seminara SB.

Eur J Endocrinol. 2006 Nov;155 Suppl 1:S3-S10.PMID: 17074994 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes.

Pitteloud N, Meysing A, Quinton R, Acierno JS Jr, Dwyer AA, Plummer L, Fliers E, Boepple P, Hayes F, Seminara S, Hughes VA, Ma J, Bouloux P, Mohammadi M, Crowley WF Jr.

Mol Cell Endocrinol. 2006 Jul 25;254-255:60-9. Epub 2006 Jun 9.PMID: 16764984 [PubMed - indexed for MEDLINE]Related articles

Neuroendocrine, gonadal, placental, and obstetric phenotypes in patients with IHH and mutations in the G-protein coupled receptor, GPR54.

Pallais JC, Bo-Abbas Y, Pitteloud N, Crowley WF Jr, Seminara SB.

Mol Cell Endocrinol. 2006 Jul 25;254-255:70-7. Epub 2006 Jun 6.PMID: 16757106 [PubMed - indexed for MEDLINE]Related articles

Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism.

Pitteloud N, Acierno JS Jr, Meysing A, Eliseenkova AV, Ma J, Ibrahimi OA, Metzger DL, Hayes FJ, Dwyer AA, Hughes VA, Yialamas M, Hall JE, Grant E, Mohammadi M, Crowley WF Jr.

Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6281-6. Epub 2006 Apr 10.PMID: 16606836 [PubMed - indexed for MEDLINE]Related articlesFree article

Testis morphology in patients with idiopathic hypogonadotropic hypogonadism.

Kumar PA, Pitteloud N, Andrews PA, Dwyer A, Hayes F, Crowley WF Jr, Dym M.

Hum Reprod. 2006 Apr;21(4):1033-40. Epub 2006 Jan 5.PMID: 16396935 [PubMed - indexed for MEDLINE]Related articlesFree article

Kallmann syndrome in a 47,XXX patient.

Corssmit EP, Seminara SB, Pitteloud N, Fliers E.

Am J Med Genet A. 2005 Nov 15;139(1):52-3. No abstract available. PMID: 16222664 [PubMed - indexed for MEDLINE]Related articles

Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men.

Pitteloud N, Mootha VK, Dwyer AA, Hardin M, Lee H, Eriksson KF, Tripathy D, Yialamas M, Groop L, Elahi D, Hayes FJ.

Diabetes Care. 2005 Jul;28(7):1636-42.PMID: 15983313 [PubMed - indexed for MEDLINE]Related articlesFree article

Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men.

Pitteloud N, Hardin M, Dwyer AA, Valassi E, Yialamas M, Elahi D, Hayes FJ.

J Clin Endocrinol Metab. 2005 May;90(5):2636-41. Epub 2005 Feb 15.PMID: 15713702 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversible kallmann syndrome, delayed puberty, and isolated anosmia occurring in a single family with a mutation in the fibroblast growth factor receptor 1 gene.

Pitteloud N, Acierno JS Jr, Meysing AU, Dwyer AA, Hayes FJ, Crowley WF Jr.

J Clin Endocrinol Metab. 2005 Mar;90(3):1317-22. Epub 2004 Dec 21.PMID: 15613419 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute stress masking the biochemical phenotype of partial androgen insensitivity syndrome in a patient with a novel mutation in the androgen receptor.

Pitteloud N, Villegas J, Dwyer AA, Crowley WF Jr, McPhaul MJ, Hayes FJ.

J Clin Endocrinol Metab. 2004 Mar;89(3):1053-8.PMID: 15001585 [PubMed - indexed for MEDLINE]Related articlesFree article

Predictors of outcome of long-term GnRH therapy in men with idiopathic hypogonadotropic hypogonadism.

Pitteloud N, Hayes FJ, Dwyer A, Boepple PA, Lee H, Crowley WF Jr.

J Clin Endocrinol Metab. 2002 Sep;87(9):4128-36.PMID: 12213860 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of prior pubertal development, biochemical markers of testicular maturation, and genetics in elucidating the phenotypic heterogeneity of idiopathic hypogonadotropic hypogonadism.

Pitteloud N, Hayes FJ, Boepple PA, DeCruz S, Seminara SB, MacLaughlin DT, Crowley WF Jr.

J Clin Endocrinol Metab. 2002 Jan;87(1):152-60.PMID: 11788640 [PubMed - indexed for MEDLINE]Related articlesFree article

Importance of inhibin B in the regulation of FSH secretion in the human male.

Hayes FJ, Pitteloud N, DeCruz S, Crowley WF Jr, Boepple PA.

J Clin Endocrinol Metab. 2001 Nov;86(11):5541-6.PMID: 11701733 [PubMed - indexed for MEDLINE]Related articlesFree article

The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormone receptor.

Pitteloud N, Boepple PA, DeCruz S, Valkenburgh SB, Crowley WF Jr, Hayes FJ.

J Clin Endocrinol Metab. 2001 Jun;86(6):2470-5.PMID: 11397842 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence, phenotypic spectrum, and modes of inheritance of gonadotropin-releasing hormone receptor mutations in idiopathic hypogonadotropic hypogonadism.

Beranova M, Oliveira LM, Bédécarrats GY, Schipani E, Vallejo M, Ammini AC, Quintos JB, Hall JE, Martin KA, Hayes FJ, Pitteloud N, Kaiser UB, Crowley WF Jr, Seminara SB.

J Clin Endocrinol Metab. 2001 Apr;86(4):1580-8.PMID: 11297587 [PubMed - indexed for MEDLINE]Related articlesFree article

Characteristics of Caucasian type 2 diabetic patients during ketoacidosis and at follow-up.

Pitteloud N, Philippe J.

Schweiz Med Wochenschr. 2000 Apr 22;130(16):576-82.PMID: 10842773 [PubMed - indexed for MEDLINE]Related articles

Ketoacidosis during gestational diabetes. Case report.

Pitteloud N, Binz K, Caulfield A, Philippe J.

Diabetes Care. 1998 Jun;21(6):1031-2. No abstract available. PMID: 9614632 [PubMed - indexed for MEDLINE]Related articlesFree article