PubMed

Prolonged follow-up after initial therapy with 2-chlorodeoxyadenosine in patients with indolent non-Hodgkin lymphoma: results of Cancer and Leukemia Group B Study 9153.

Blum KA, Johnson JL, Niedzwiecki D, Piro LD, Saven A, Peterson BA, Byrd JC, Cheson BD; Cancer and Leukemia Group B Study 9153.

Cancer. 2006 Dec 15;107(12):2817-25.PMID: 17120198 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced survival associated with vitiligo expression during maintenance biotherapy for metastatic melanoma.

Boasberg PD, Hoon DS, Piro LD, Martin MA, Fujimoto A, Kristedja TS, Bhachu S, Ye X, Deck RR, O'Day SJ.

J Invest Dermatol. 2006 Dec;126(12):2658-63. Epub 2006 Aug 31.PMID: 16946711 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptosis, Bcl-2 antisense, and cancer therapy.

Piro LD.

Oncology (Williston Park). 2004 Nov;18(13 Suppl 10):5-10. Review.PMID: 15651171 [PubMed - indexed for MEDLINE]Related articles

Extended Rituximab (anti-CD20 monoclonal antibody) therapy for relapsed or refractory low-grade or follicular non-Hodgkin's lymphoma.

Piro LD, White CA, Grillo-López AJ, Janakiraman N, Saven A, Beck TM, Varns C, Shuey S, Czuczman M, Lynch JW, Kolitz JE, Jain V.

Ann Oncol. 1999 Jun;10(6):655-61.PMID: 10442187 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term follow-up of patients with hairy cell leukemia after cladribine treatment.

Saven A, Burian C, Koziol JA, Piro LD.

Blood. 1998 Sep 15;92(6):1918-26.PMID: 9731048 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced charges and costs associated with outpatient autologous stem cell transplantation.

Meisenberg BR, Ferran K, Hollenbach K, Brehm T, Jollon J, Piro LD.

Bone Marrow Transplant. 1998 May;21(9):927-32.PMID: 9613786 [PubMed - indexed for MEDLINE]Related articlesFree article

2-chlorodeoxyadenosine administration to patients with the myeloid blast phase of chronic myelogenous leukemia.

Gollard R, Miller WE, Piro LD, Saven A.

Leuk Lymphoma. 1997 Dec;28(1-2):183-5.PMID: 9498718 [PubMed - indexed for MEDLINE]Related articles

Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.

Krajewski S, Gascoyne RD, Zapata JM, Krajewska M, Kitada S, Chhanabhai M, Horsman D, Berean K, Piro LD, Fugier-Vivier I, Liu YJ, Wang HG, Reed JC.

Blood. 1997 May 15;89(10):3817-25.PMID: 9160689 [PubMed - indexed for MEDLINE]Related articlesFree article

Outpatient high-dose chemotherapy with autologous stem-cell rescue for hematologic and nonhematologic malignancies.

Meisenberg BR, Miller WE, McMillan R, Callaghan M, Sloan C, Brehm T, Kosty MP, Kroener J, Longmire R, Saven A, Piro LD.

J Clin Oncol. 1997 Jan;15(1):11-7.PMID: 8996119 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine: a potent antimetabolite with major activity in the treatment of indolent lymphoproliferative disorders.

Saven A, Piro LD.

Hematol Cell Ther. 1996 Dec;38 Suppl 2:S93-101. Review.PMID: 9137962 [PubMed - indexed for MEDLINE]Related articles

Prolonged, complete remission after 2-chlorodeoxyadenosine therapy in a patient with refractory essential mixed cryoglobulinemia.

Lee TC, Miller WE, Curd JG, Piro LD, Saven A.

Mayo Clin Proc. 1996 Oct;71(10):966-8.PMID: 8820771 [PubMed - indexed for MEDLINE]Related articles

New perspectives on the approach to chronic lymphocytic leukemia.

Goodman MG, Spinosa JC, Saven A, Piro LD, Wormsley S.

Leuk Lymphoma. 1996 Jun;22(1-2):1-10. Review.PMID: 8724523 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetic study of oral and bolus intravenous 2-chlorodeoxyadenosine in patients with malignancy.

Saven A, Cheung WK, Smith I, Moyer M, Johannsen T, Rose E, Gollard R, Kosty M, Miller WE, Piro LD.

J Clin Oncol. 1996 Mar;14(3):978-83.PMID: 8622049 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine treatment of lymphoma.

Saven A, Piro LD.

Cancer Treat Res. 1996;85:15-26. Review. No abstract available. PMID: 9043772 [PubMed - indexed for MEDLINE]Related articles

Purine nucleoside therapy of low-grade follicular lymphoma.

Piro LD.

Ann Oncol. 1996;7 Suppl 6:S41-7. Review.PMID: 9010578 [PubMed - indexed for MEDLINE]Related articles

Cladribine in the treatment of low-grade non-Hodgkin's lymphoma.

Piro LD.

Semin Hematol. 1996 Jan;33(1 Suppl 1):34-9. Review. No abstract available. PMID: 8714615 [PubMed - indexed for MEDLINE]Related articles

The optimal management of hairy cell leukaemia.

Gollard R, Lee TC, Piro LD, Saven A.

Drugs. 1995 Jun;49(6):921-31. Review.PMID: 7543840 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine activity in patients with untreated chronic lymphocytic leukemia.

Saven A, Lemon RH, Kosty M, Beutler E, Piro LD.

J Clin Oncol. 1995 Mar;13(3):570-4.PMID: 7884417 [PubMed - indexed for MEDLINE]Related articles

Immunomorphologic analysis of bone marrow biopsies after treatment with 2-chlorodeoxyadenosine for hairy cell leukemia.

Ellison DJ, Sharpe RW, Robbins BA, Spinosa JC, Leopard JD, Saven A, Piro LD.

Blood. 1994 Dec 15;84(12):4310-5.PMID: 7994047 [PubMed - indexed for MEDLINE]Related articlesFree article

Loxoribine induces chronic lymphocytic leukemia B cells to traverse the cell cycle.

Goodman MG, Wormsley SB, Spinosa JC, Piro LD.

Blood. 1994 Nov 15;84(10):3457-64.PMID: 7949100 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of monoclonal immunoglobulins and quantitative immunoglobulin abnormalities in hairy cell leukemia and chronic lymphocytic leukemia.

Hansen DA, Robbins BA, Bylund DJ, Piro LD, Saven A, Ellison DJ.

Am J Clin Pathol. 1994 Nov;102(5):580-5.PMID: 7942620 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine-induced complete remissions in Langerhans-cell histiocytosis.

Saven A, Foon KA, Piro LD.

Ann Intern Med. 1994 Sep 15;121(6):430-2. No abstract available. PMID: 7914398 [PubMed - indexed for MEDLINE]Related articlesFree article

Complete hematologic remissions in chronic-phase, Philadelphia-chromosome-positive, chronic myelogenous leukemia after 2-chlorodeoxyadenosine.

Saven A, Piro LD, Lemon RH, Figueroa ML, Kosty M, Ellison DJ, Beutler E.

Cancer. 1994 Jun 15;73(12):2953-63.PMID: 7911068 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine: a newer purine analog active in the treatment of indolent lymphoid malignancies.

Saven A, Piro LD.

Ann Intern Med. 1994 May 1;120(9):784-91. Review.PMID: 7908507 [PubMed - indexed for MEDLINE]Related articlesFree article

Purine metabolism of lymphocytes. Targets for chemotherapy drug development.

Carrera CJ, Saven A, Piro LD.

Hematol Oncol Clin North Am. 1994 Apr;8(2):357-81. Review.PMID: 8040145 [PubMed - indexed for MEDLINE]Related articles

The Scripps Clinic experience with 2-chlorodeoxyadenosine in the treatment of hairy cell leukemia.

Piro LD, Ellison DJ, Saven A.

Leuk Lymphoma. 1994;14 Suppl 1:121-5.PMID: 7820043 [PubMed - indexed for MEDLINE]Related articles

The newer purine analogs. Significant therapeutic advance in the management of lymphoid malignancies.

Saven A, Piro LD.

Cancer. 1993 Dec 1;72(11 Suppl):3470-83. Review.PMID: 7902205 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine: treatment of hairy cell leukemia, chronic lymphocytic leukemia, and lymphocytic lymphoma.

Piro LD.

Semin Hematol. 1993 Oct;30(4 Suppl 6):28-30. Review. No abstract available. PMID: 7908756 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine to treat refractory histiocytosis X.

Saven A, Figueroa ML, Piro LD, Rosenblatt JD.

N Engl J Med. 1993 Sep 2;329(10):734-5. No abstract available. PMID: 8102196 [PubMed - indexed for MEDLINE]Related articles

Complete remissions in hairy cell leukemia with 2-chlorodeoxyadenosine after failure with 2'-deoxycoformycin.

Saven A, Piro LD.

Ann Intern Med. 1993 Aug 15;119(4):278-83.PMID: 8101069 [PubMed - indexed for MEDLINE]Related articlesFree article

Diagnostic application of two-color flow cytometry in 161 cases of hairy cell leukemia.

Robbins BA, Ellison DJ, Spinosa JC, Carey CA, Lukes RJ, Poppema S, Saven A, Piro LD.

Blood. 1993 Aug 15;82(4):1277-87.PMID: 7688993 [PubMed - indexed for MEDLINE]Related articlesFree article

2-Chlorodeoxyadenosine dose escalation in nonhematologic malignancies.

Saven A, Kawasaki H, Carrera CJ, Waltz T, Copeland B, Zyroff J, Kosty M, Carson DA, Beutler E, Piro LD.

J Clin Oncol. 1993 Apr;11(4):671-8.PMID: 8097527 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine for patients with B-cell chronic lymphocytic leukemia resistant to fludarabine.

Saven A, Lemon RH, Piro LD.

N Engl J Med. 1993 Mar 18;328(11):812-3. No abstract available. PMID: 8094889 [PubMed - indexed for MEDLINE]Related articles

Relationship of deoxycytidine kinase and cytoplasmic 5'-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine.

Kawasaki H, Carrera CJ, Piro LD, Saven A, Kipps TJ, Carson DA.

Blood. 1993 Feb 1;81(3):597-601.PMID: 8094016 [PubMed - indexed for MEDLINE]Related articlesFree article

2-Chlorodeoxyadenosine in the treatment of hairy cell leukemia.

Saven A, Piro LD.

Cancer Invest. 1993;11(5):559-64. Review. No abstract available. PMID: 8104670 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine: a new nucleoside agent effective in the treatment of lymphoid malignancies.

Saven A, Piro LD.

Leuk Lymphoma. 1993;10 Suppl:43-9. Review. No abstract available. PMID: 8097654 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine in the treatment of hairy cell leukemia and chronic lymphocytic leukemia.

Saven A, Piro LD.

Leuk Lymphoma. 1993;11 Suppl 2:109-14. Review.PMID: 7907251 [PubMed - indexed for MEDLINE]Related articles

Hairy cell leukemia: new understanding of biology and treatment.

Saven A, Piro LD, Carrera CJ, Carson DA, Beutler E.

Cancer Treat Res. 1993;64:15-34. Review. No abstract available. PMID: 7680875 [PubMed - indexed for MEDLINE]Related articles

Lymphocytic leukemias: new insights into biology and therapy.

Foon KA, Piro LD.

Leukemia. 1992 Nov;6 Suppl 4:26-32. Review. No abstract available. PMID: 1434827 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine: drug development priorities.

Piro LD.

J Clin Oncol. 1992 Oct;10(10):1507-10. No abstract available. PMID: 1357106 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T-cell lymphoma.

Saven A, Carrera CJ, Carson DA, Beutler E, Piro LD.

Blood. 1992 Aug 1;80(3):587-92.PMID: 1353380 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of hairy cell leukemia.

Saven A, Piro LD.

Blood. 1992 Mar 1;79(5):1111-20. Review. No abstract available. PMID: 1371410 [PubMed - indexed for MEDLINE]Related articlesFree article

2-Chlorodeoxyadenosine treatment of low-grade lymphomas.

Kay AC, Saven A, Carrera CJ, Carson DA, Thurston D, Beutler E, Piro LD.

J Clin Oncol. 1992 Mar;10(3):371-7.PMID: 1346801 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine treatment of lymphoid malignancies.

Piro LD.

Blood. 1992 Feb 15;79(4):843-5. No abstract available. PMID: 1346575 [PubMed - indexed for MEDLINE]Related articlesFree article

2-Chlorodeoxyadenosine chemotherapy triggers programmed cell death in normal and malignant lymphocytes.

Carrera CJ, Piro LD, Saven A, Beutler E, Terai C, Carson DA.

Adv Exp Med Biol. 1991;309A:15-8. No abstract available. PMID: 1686349 [PubMed - indexed for MEDLINE]Related articles

Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy.

Carrera CJ, Terai C, Lotz M, Curd JG, Piro LD, Beutler E, Carson DA.

J Clin Invest. 1990 Nov;86(5):1480-8.PMID: 1700795 [PubMed - indexed for MEDLINE]Related articlesFree article

Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine.

Piro LD, Carrera CJ, Carson DA, Beutler E.

N Engl J Med. 1990 Apr 19;322(16):1117-21.PMID: 1969613 [PubMed - indexed for MEDLINE]Related articles

Activity of 2-chloro-2'-deoxyadenosine in chronic lymphocytic leukemia, hairy cell leukemia, and autoimmune hemolytic anemia.

Carson DA, Piro LD, Wasson DB, Carrera CJ, Beutler E.

Adv Exp Med Biol. 1989;253A:427-31. Review. No abstract available. PMID: 2576181 [PubMed - indexed for MEDLINE]Related articles

Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo.

Carrera CJ, Yamanaka H, Piro LD, Lotz M, Carson DA.

Adv Exp Med Biol. 1989;253B:219-25.PMID: 2575348 [PubMed - indexed for MEDLINE]Related articles

2-Chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukemia.

Piro LD, Carrera CJ, Beutler E, Carson DA.

Blood. 1988 Sep;72(3):1069-73.PMID: 2901280 [PubMed - indexed for MEDLINE]Related articlesFree article