PubMed

FOXP3 forkhead domain mutation and regulatory T cells in the IPEX syndrome.

d'Hennezel E, Ben-Shoshan M, Ochs HD, Torgerson TR, Russell LJ, Lejtenyi C, Noya FJ, Jabado N, Mazer B, Piccirillo CA.

N Engl J Med. 2009 Oct 22;361(17):1710-3. No abstract available. PMID: 19846862 [PubMed - indexed for MEDLINE]Related articles

Control of type 1 diabetes by CD4+Foxp3+ regulatory T cells: lessons from mouse models and implications for human disease.

Sgouroudis E, Piccirillo CA.

Diabetes Metab Res Rev. 2009 Mar;25(3):208-18. Review.PMID: 19214972 [PubMed - indexed for MEDLINE]Related articles

Tolerance, immune regulation, and autoimmunity: cells and cytokines that make a difference.

Pelanda R, Piccirillo CA.

Curr Opin Immunol. 2008 Dec;20(6):629-31. Epub 2008 Nov 17. No abstract available. PMID: 18977298 [PubMed - indexed for MEDLINE]Related articles

Impact of protective IL-2 allelic variants on CD4+ Foxp3+ regulatory T cell function in situ and resistance to autoimmune diabetes in NOD mice.

Sgouroudis E, Albanese A, Piccirillo CA.

J Immunol. 2008 Nov 1;181(9):6283-92.PMID: 18941219 [PubMed - indexed for MEDLINE]Related articlesFree article

CD4+Foxp3+ regulatory T cells in the control of autoimmunity: in vivo veritas.

Piccirillo CA, d'Hennezel E, Sgouroudis E, Yurchenko E.

Curr Opin Immunol. 2008 Dec;20(6):655-62. Epub 2008 Oct 28.PMID: 18926906 [PubMed - indexed for MEDLINE]Related articles

The role of T-regulatory cells and Toll-like receptors in the pathogenesis of human inflammatory bowel disease.

Himmel ME, Hardenberg G, Piccirillo CA, Steiner TS, Levings MK.

Immunology. 2008 Oct;125(2):145-53. Review.PMID: 18798918 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulatory T cells in health and disease.

Piccirillo CA.

Cytokine. 2008 Sep;43(3):395-401. Epub 2008 Aug 22. Review.PMID: 18722786 [PubMed - indexed for MEDLINE]Related articles

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction.

Tang Q, Adams JY, Penaranda C, Melli K, Piaggio E, Sgouroudis E, Piccirillo CA, Salomon BL, Bluestone JA.

Immunity. 2008 May;28(5):687-97. Epub 2008 May 8.PMID: 18468463 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell line-dependent internalization pathways and intracellular trafficking determine transfection efficiency of nanoparticle vectors.

Douglas KL, Piccirillo CA, Tabrizian M.

Eur J Pharm Biopharm. 2008 Mar;68(3):676-87. Epub 2007 Sep 15.PMID: 17945472 [PubMed - indexed for MEDLINE]Related articles

Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes.

Tritt M, Sgouroudis E, d'Hennezel E, Albanese A, Piccirillo CA.

Diabetes. 2008 Jan;57(1):113-23. Epub 2007 Oct 10.PMID: 17928397 [PubMed - indexed for MEDLINE]Related articlesFree article

T regulatory cells control numbers of NK cells and CD8alpha+ immature dendritic cells in the lymph node paracortex.

Giroux M, Yurchenko E, St-Pierre J, Piccirillo CA, Perreault C.

J Immunol. 2007 Oct 1;179(7):4492-502.PMID: 17878345 [PubMed - indexed for MEDLINE]Related articlesFree article

TGF-beta1 modulates Foxp3 expression and regulatory activity in distinct CD4+ T cell subsets.

Pyzik M, Piccirillo CA.

J Leukoc Biol. 2007 Aug;82(2):335-46. Epub 2007 May 2.PMID: 17475784 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional dynamics of naturally occurring regulatory T cells in health and autoimmunity.

Levings MK, Allan S, d'Hennezel E, Piccirillo CA.

Adv Immunol. 2006;92:119-55. Review.PMID: 17145303 [PubMed - indexed for MEDLINE]Related articles

Ubiquitous expression of mRFP-1 in vivo by site-directed transgenesis.

Yurchenko E, Friedman H, Hay V, Peterson A, Piccirillo CA.

Transgenic Res. 2007 Feb;16(1):29-40. Epub 2006 Nov 1.PMID: 17077985 [PubMed - indexed for MEDLINE]Related articles

Effects of alginate inclusion on the vector properties of chitosan-based nanoparticles.

Douglas KL, Piccirillo CA, Tabrizian M.

J Control Release. 2006 Oct 27;115(3):354-61. Epub 2006 Sep 6.PMID: 17045691 [PubMed - indexed for MEDLINE]Related articles

CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence.

Yurchenko E, Tritt M, Hay V, Shevach EM, Belkaid Y, Piccirillo CA.

J Exp Med. 2006 Oct 30;203(11):2451-60. Epub 2006 Oct 2.PMID: 17015634 [PubMed - indexed for MEDLINE]Related articlesFree article

The TGF-beta1/Foxp3 regulatory axis in immune self-tolerance: implications for health and disease.

Pyzik M, Piccirillo CA.

Inflamm Allergy Drug Targets. 2006 Sep;5(3):167-77. Review.PMID: 16918480 [PubMed - indexed for MEDLINE]Related articles

Development and function of naturally occurring CD4+CD25+ regulatory T cells.

Toda A, Piccirillo CA.

J Leukoc Biol. 2006 Sep;80(3):458-70. Epub 2006 Jun 29. Review.PMID: 16809644 [PubMed - indexed for MEDLINE]Related articlesFree article

Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens.

Suffia IJ, Reckling SK, Piccirillo CA, Goldszmid RS, Belkaid Y.

J Exp Med. 2006 Mar 20;203(3):777-88. Epub 2006 Mar 13.PMID: 16533885 [PubMed - indexed for MEDLINE]Related articlesFree article

Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C.

Manigold T, Shin EC, Mizukoshi E, Mihalik K, Murthy KK, Rice CM, Piccirillo CA, Rehermann B.

Blood. 2006 Jun 1;107(11):4424-32. Epub 2006 Feb 14.PMID: 16478885 [PubMed - indexed for MEDLINE]Related articlesFree article

TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation.

Kullberg MC, Hay V, Cheever AW, Mamura M, Sher A, Letterio JJ, Shevach EM, Piccirillo CA.

Eur J Immunol. 2005 Oct;35(10):2886-95.PMID: 16180248 [PubMed - indexed for MEDLINE]Related articles

Control of type 1 autoimmune diabetes by naturally occurring CD4+CD25+ regulatory T lymphocytes in neonatal NOD mice.

Piccirillo CA, Tritt M, Sgouroudis E, Albanese A, Pyzik M, Hay V.

Ann N Y Acad Sci. 2005 Jun;1051:72-87. Review.PMID: 16126946 [PubMed - indexed for MEDLINE]Related articles

CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

Antony PA, Piccirillo CA, Akpinarli A, Finkelstein SE, Speiss PJ, Surman DR, Palmer DC, Chan CC, Klebanoff CA, Overwijk WW, Rosenberg SA, Restifo NP.

J Immunol. 2005 Mar 1;174(5):2591-601.PMID: 15728465 [PubMed - indexed for MEDLINE]Related articlesFree article

Role for CD4(+) CD25(+) regulatory T cells in reactivation of persistent leishmaniasis and control of concomitant immunity.

Mendez S, Reckling SK, Piccirillo CA, Sacks D, Belkaid Y.

J Exp Med. 2004 Jul 19;200(2):201-10.PMID: 15263027 [PubMed - indexed for MEDLINE]Related articlesFree article

Cornerstone of peripheral tolerance: naturally occurring CD4+CD25+ regulatory T cells.

Piccirillo CA, Thornton AM.

Trends Immunol. 2004 Jul;25(7):374-80. Review. No abstract available. PMID: 15207505 [PubMed - indexed for MEDLINE]Related articles

Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.

Thornton AM, Donovan EE, Piccirillo CA, Shevach EM.

J Immunol. 2004 Jun 1;172(11):6519-23.PMID: 15153463 [PubMed - indexed for MEDLINE]Related articlesFree article

Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance.

Piccirillo CA, Shevach EM.

Semin Immunol. 2004 Apr;16(2):81-8. Review.PMID: 15036231 [PubMed - indexed for MEDLINE]Related articles

The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells.

Hesse M, Piccirillo CA, Belkaid Y, Prufer J, Mentink-Kane M, Leusink M, Cheever AW, Shevach EM, Wynn TA.

J Immunol. 2004 Mar 1;172(5):3157-66.PMID: 14978122 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation requirements for the induction of CD4+CD25+ T cell suppressor function.

Thornton AM, Piccirillo CA, Shevach EM.

Eur J Immunol. 2004 Feb;34(2):366-76.PMID: 14768041 [PubMed - indexed for MEDLINE]Related articles

Control of T cell activation by CD4+CD25+ suppressor T cells.

Shevach EM, Piccirillo CA, Thornton AM, McHugh RS.

Novartis Found Symp. 2003;252:24-36; discussion 36-44, 106-14. Review.PMID: 14609210 [PubMed - indexed for MEDLINE]Related articles

Immune modulation by plasmid DNA-mediated cytokine gene transfer.

Piccirillo CA, Prud'homme GJ.

Curr Pharm Des. 2003;9(1):83-94. Review.PMID: 12570678 [PubMed - indexed for MEDLINE]Related articles

Gene therapy with plasmids encoding cytokine- or cytokine receptor--IgG chimeric proteins.

Piccirillo CA, Prud'homme GJ.

Methods Mol Biol. 2003;215:153-70. No abstract available. PMID: 12512296 [PubMed - indexed for MEDLINE]Related articles

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity.

Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL.

Nature. 2002 Dec 5;420(6915):502-7.PMID: 12466842 [PubMed - indexed for MEDLINE]Related articles

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness.

Piccirillo CA, Letterio JJ, Thornton AM, McHugh RS, Mamura M, Mizuhara H, Shevach EM.

J Exp Med. 2002 Jul 15;196(2):237-46.PMID: 12119348 [PubMed - indexed for MEDLINE]Related articlesFree article

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor.

McHugh RS, Whitters MJ, Piccirillo CA, Young DA, Shevach EM, Collins M, Byrne MC.

Immunity. 2002 Feb;16(2):311-23.PMID: 11869690 [PubMed - indexed for MEDLINE]Related articles

Control of T-cell activation by CD4+ CD25+ suppressor T cells.

Shevach EM, McHugh RS, Piccirillo CA, Thornton AM.

Immunol Rev. 2001 Aug;182:58-67. Review.PMID: 11722623 [PubMed - indexed for MEDLINE]Related articles

Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells.

Piccirillo CA, Shevach EM.

J Immunol. 2001 Aug 1;167(3):1137-40.PMID: 11466326 [PubMed - indexed for MEDLINE]Related articlesFree article

The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases.

Prud'homme GJ, Piccirillo CA.

J Autoimmun. 2000 Feb;14(1):23-42. Review.PMID: 10648114 [PubMed - indexed for MEDLINE]Related articles

Prevention of experimental allergic encephalomyelitis by intramuscular gene transfer with cytokine-encoding plasmid vectors.

Piccirillo CA, Prud'homme GJ.

Hum Gene Ther. 1999 Aug 10;10(12):1915-22.PMID: 10466625 [PubMed - indexed for MEDLINE]Related articles

TGF-beta1 somatic gene therapy prevents autoimmune disease in nonobese diabetic mice.

Piccirillo CA, Chang Y, Prud'homme GJ.

J Immunol. 1998 Oct 15;161(8):3950-6.PMID: 9780163 [PubMed - indexed for MEDLINE]Related articlesFree article